LOCUS       NM_173753               6281 bp    mRNA    linear   ROD 17-JUL-2024
DEFINITION  Mus musculus folliculin interacting protein 1 (Fnip1), mRNA.
ACCESSION   NM_173753 XM_109657
VERSION     NM_173753.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6281)
  AUTHORS   Mao,Y., Jin,Z., Yang,J., Xu,D., Zhao,L., Kiram,A., Yin,Y., Zhou,D.,
            Sun,Z., Xiao,L., Zhou,Z., Yang,L., Fu,T., Xu,Z., Jia,Y., Chen,X.,
            Niu,F.N., Li,X., Zhu,Z. and Gan,Z.
  TITLE     Muscle-bone cross-talk through the FNIP1-TFEB-IGF2 axis is
            associated with bone metabolism in human and mouse
  JOURNAL   Sci Transl Med 16 (750), eadk9811 (2024)
   PUBMED   38838134
  REMARK    GeneRIF: Muscle-bone cross-talk through the FNIP1-TFEB-IGF2 axis is
            associated with bone metabolism in human and mouse.
REFERENCE   2  (bases 1 to 6281)
  AUTHORS   Xiao,L., Yin,Y., Sun,Z., Liu,J., Jia,Y., Yang,L., Mao,Y., Peng,S.,
            Xie,Z., Fang,L., Li,J., Xie,X. and Gan,Z.
  TITLE     AMPK phosphorylation of FNIP1 (S220) controls mitochondrial
            function and muscle fuel utilization during exercise
  JOURNAL   Sci Adv 10 (6), eadj2752 (2024)
   PUBMED   38324677
  REMARK    GeneRIF: AMPK phosphorylation of FNIP1 (S220) controls
            mitochondrial function and muscle fuel utilization during exercise.
REFERENCE   3  (bases 1 to 6281)
  AUTHORS   Sun,Z., Yang,L., Kiram,A., Yang,J., Yang,Z., Xiao,L., Yin,Y.,
            Liu,J., Mao,Y., Zhou,D., Yu,H., Zhou,Z., Xu,D., Jia,Y., Ding,C.,
            Guo,Q., Wang,H., Li,Y., Wang,L., Fu,T., Hu,S. and Gan,Z.
  TITLE     FNIP1 abrogation promotes functional revascularization of ischemic
            skeletal muscle by driving macrophage recruitment
  JOURNAL   Nat Commun 14 (1), 7136 (2023)
   PUBMED   37932296
  REMARK    GeneRIF: FNIP1 abrogation promotes functional revascularization of
            ischemic skeletal muscle by driving macrophage recruitment.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6281)
  AUTHORS   Shillingford,J.M. and Shayman,J.A.
  TITLE     Functional TFEB activation characterizes multiple models of renal
            cystic disease and loss of polycystin-1
  JOURNAL   Am J Physiol Renal Physiol 324 (4), F404-F422 (2023)
   PUBMED   36794754
REFERENCE   5  (bases 1 to 6281)
  AUTHORS   Yin,Y., Xu,D., Mao,Y., Xiao,L., Sun,Z., Liu,J., Zhou,D., Xu,Z.,
            Liu,L., Fu,T., Ding,C., Guo,Q., Sun,W., Zhou,Z., Yang,L., Jia,Y.,
            Chen,X. and Gan,Z.
  TITLE     FNIP1 regulates adipocyte browning and systemic glucose homeostasis
            in mice by shaping intracellular calcium dynamics
  JOURNAL   J Exp Med 219 (5) (2022)
   PUBMED   35412553
  REMARK    GeneRIF: FNIP1 regulates adipocyte browning and systemic glucose
            homeostasis in mice by shaping intracellular calcium dynamics.
REFERENCE   6  (bases 1 to 6281)
  AUTHORS   Petit,C.S., Roczniak-Ferguson,A. and Ferguson,S.M.
  TITLE     Recruitment of folliculin to lysosomes supports the amino
            acid-dependent activation of Rag GTPases
  JOURNAL   J Cell Biol 202 (7), 1107-1122 (2013)
   PUBMED   24081491
REFERENCE   7  (bases 1 to 6281)
  AUTHORS   Betschinger,J., Nichols,J., Dietmann,S., Corrin,P.D., Paddison,P.J.
            and Smith,A.
  TITLE     Exit from pluripotency is gated by intracellular redistribution of
            the bHLH transcription factor Tfe3
  JOURNAL   Cell 153 (2), 335-347 (2013)
   PUBMED   23582324
REFERENCE   8  (bases 1 to 6281)
  AUTHORS   Baba,M., Keller,J.R., Sun,H.W., Resch,W., Kuchen,S., Suh,H.C.,
            Hasumi,H., Hasumi,Y., Kieffer-Kwon,K.R., Gonzalez,C.G.,
            Hughes,R.M., Klein,M.E., Oh,H.F., Bible,P., Southon,E.,
            Tessarollo,L., Schmidt,L.S., Linehan,W.M. and Casellas,R.
  TITLE     The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dube
            syndrome is required for murine B-cell development
  JOURNAL   Blood 120 (6), 1254-1261 (2012)
   PUBMED   22709692
REFERENCE   9  (bases 1 to 6281)
  AUTHORS   Park,H., Staehling,K., Tsang,M., Appleby,M.W., Brunkow,M.E.,
            Margineantu,D., Hockenbery,D.M., Habib,T., Liggitt,H.D., Carlson,G.
            and Iritani,B.M.
  TITLE     Disruption of Fnip1 reveals a metabolic checkpoint controlling B
            lymphocyte development
  JOURNAL   Immunity 36 (5), 769-781 (2012)
   PUBMED   22608497
REFERENCE   10 (bases 1 to 6281)
  AUTHORS   Hasumi,H., Baba,M., Hong,S.B., Hasumi,Y., Huang,Y., Yao,M.,
            Valera,V.A., Linehan,W.M. and Schmidt,L.S.
  TITLE     Identification and characterization of a novel
            folliculin-interacting protein FNIP2
  JOURNAL   Gene 415 (1-2), 60-67 (2008)
   PUBMED   18403135
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY239060.1, BC079892.1 and AL596127.12.
            
            On Dec 16, 2009 this sequence version replaced NM_173753.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079892.1, AK122574.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                BY239060.1         1-10
            11-4102             BC079892.1         1-4092
            4103-6281           AL596127.12        182549-184727
FEATURES             Location/Qualifiers
     source          1..6281
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 32.13 cM"
     gene            1..6281
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /note="folliculin interacting protein 1"
                     /db_xref="GeneID:216742"
                     /db_xref="MGI:MGI:2444668"
     exon            1..210
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..3616
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /codon_start=1
                     /product="folliculin-interacting protein 1"
                     /protein_id="NP_776114.2"
                     /db_xref="CCDS:CCDS24698.1"
                     /db_xref="GeneID:216742"
                     /db_xref="MGI:MGI:2444668"
                     /translation="MAPTLFQKLFSKRSGLGAPGRDARDPDCAFSWPLPEFDPSQIRL
                     IVYQDCERRGRNVLFDSSVKRKNEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSSSLDS
                     SITLSSDGKDQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLS
                     KVFTARTGSSICGSLNTLQDSLEFINQDSNTLKADSSTVSNGLLGNIGLSQFCSPRRA
                     FSEQGPLRLIRSASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLFITPFPSPNSS
                     LTRSCASSYQRRWRRSQTTSLENGVFPRWSVEESFNLSDESCGPNPGIVRKKKIAIGV
                     IFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAYNR
                     ILDALTEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENASKNQ
                     FLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVGMLAKTHPYNPLWAQLGD
                     LYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPG
                     TVITTTLEKGEIEESEYVLITMHRNKSSLLFKESEETRTPNCNCKYCSHPVLGQNTEN
                     VSQPEREDTQDNSKELLGISDECQKISPPDCQEENAVDVQQYRDKLRTCLDTKLETVV
                     CTGSAPADKCVLSETCLEPREESWQNKELLDSDNHTGTAMRPTGIVVEKKPPDKNVPS
                     AFSCEVTQTKVTFLIGDSMSPDSDTELRSQAVVDQINRHHSEPLKEDRGVADKHQESK
                     ITKDQSEDSDTQNIVSGESCELPCWSHSDPESMSLFDEYFNDDSIETRTIDDVPVKTS
                     TDSKEYCCMLEYPKRLYTKTNKQKSELCKCIETVHQDSCNACFPQQDQRNSLSILVPH
                     GDKESSDKKNAVGTEWDIPRNESSDSALGDSESEDTGPDIRRQAGGYCGGDQEDWTEE
                     DEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGNDERLRQCLVSDL
                     SHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHS
                     TLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDL
                     PLLAAVASTHSPYVAQILL"
     exon            211..337
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            338..472
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            473..573
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            574..648
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            649..740
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            741..824
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            825..896
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1032
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1234
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1320
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1467
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1637
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..3054
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3055..3223
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3224..3421
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..3537
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3538..6281
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6254..6259
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6276
                     /gene="Fnip1"
                     /gene_synonym="A730024A03Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaagtgacta atttctgtca tatgactgag gcgcccatgg gggtggcggg gtggcggtag
       61 gagcgggggg cctcctgcga gctcccagcc gagcgacccc agtcttgcgg cggccagcat
      121 ggcccccacc ctgttccaga agctcttcag caagcggagc ggattaggcg cgccgggacg
      181 agacgcccgc gacccggact gcgcgttcag ttggcccttg ccagaatttg acccaagtca
      241 gattcgactg atcgtatatc aagactgtga aagacgaggg agaaatgtat tgtttgactc
      301 cagtgttaag agaaaaaatg aggacacatc agtatcgaag ctctgtaatg atgctcaagt
      361 caaggtcttt gggaagtgct gccagctgaa gccaggagga gatagttctt cctctttgga
      421 tagctctatc actttatctt ctgatggaaa agaccagtgt cccaaatacc agggttctcg
      481 gtgttcttct gatgccaata tgcttggaga gatgatgttt ggctcagtag caatgagcta
      541 caaaggatcc accttaaaaa ttcatcagat ccgctcgcct ccacagctta tgcttagcaa
      601 agttttcacc gcacggactg gcagtagtat ctgtgggagt ctcaatactc tgcaggacag
      661 tcttgaattc atcaatcagg acagtaatac attgaaagct gatagcagca cagttagtaa
      721 tgggctgctt ggaaatatag gtctttcaca gttctgcagc cccaggcggg ctttctctga
      781 gcagggtccg ctccgcctga tcaggagtgc ctctttcttt gcagttcaca gcaacccaat
      841 ggacatgcca ggaagagaac tgaatgagga cagagacagc ggcatagcac gttctgcatc
      901 tctgagcagc ttgttcatca ccccattccc ctccccaaac tcttcactta cccgaagctg
      961 tgctagcagc taccagcgac gttggcgacg tagccaaaca acaagtttgg aaaatggggt
     1021 gtttcctaga tggtctgtag aagaaagctt taatctgtca gatgaaagtt gtggccctaa
     1081 tccaggaatt gtgaggaaaa agaagattgc aattggggta atcttttcat tatccaaaga
     1141 tgaagatgaa aataacaaat tcaatgaatt ctttttttca cattttcctc tctttgaaag
     1201 ccacatgaac aaattaaaaa gtgcaataga acaggcaatg aaaatgagcc ggagatcagc
     1261 tgatgccagc cagagaagtt tggcatacaa tcgaatactt gatgccctga ctgagttcag
     1321 aacaacaatt tgtaatcttt atacaatgcc aagaattggg gaacctgtct ggcttacaat
     1381 gatgtcaggg actccagaga agaaccagct ttgccatcgt ttcatgaagg aattcacctt
     1441 tctaatggaa aatgcctcca aaaatcaatt cttgccagct ctcattactg cagttttgac
     1501 caatcatctt gcctgggttc caacagtcat gccaaatgga cagccaccta taaaaatatt
     1561 tttagaaaaa cattcctctc agagtgtggg catgttggca aagactcatc catataaccc
     1621 tctttgggca caacttggag atttgtatgg cgctattgga tctcctgtac ggttagcaag
     1681 aactgtagtc gttggcaaac gacaagacct ggtccagaga ctgctttatt ttcttactta
     1741 cttcatcaga tgctctgaac ttcaagaaac ccatctttta gaaaatggag aagatgaagc
     1801 cattgttatg ccaggcacag tgattactac cactttagaa aagggggaaa tagaggaatc
     1861 agagtatgtg ctaatcacaa tgcatagaaa caaaagcagc ttgctcttta aagagtcaga
     1921 agagacaaga actcccaact gtaactgtaa atattgcagt catccagtcc ttgggcaaaa
     1981 tacagagaat gtgtcacaac cagaaagaga agatactcaa gacaactcta aggaattgct
     2041 aggaatttca gatgaatgcc aaaagatttc tcctcctgac tgccaagaag aaaatgctgt
     2101 tgatgttcaa cagtacagag ataaattaag aacttgcctt gacaccaagt tagagacagt
     2161 tgtttgtaca ggatctgctc cagccgacaa atgtgtgttg tcagagacat gcttggaacc
     2221 aagagaagaa tcctggcaga ataaggaatt gctggattca gataatcaca caggcacagc
     2281 aatgagaccc acaggaatag ttgttgaaaa gaaacctcca gataagaatg tgcccagtgc
     2341 attttcctgt gaggtaactc agacaaaggt tacgttcttg attggagatt ctatgtcacc
     2401 tgattcagat actgaacttc ggagtcaggc tgtggtggat cagattaaca gacatcacag
     2461 cgaaccacta aaggaagaca gaggagtggc tgataagcat caagaaagta aaataactaa
     2521 ggaccaatct gaagactctg acacacagaa catagtttct ggagagtcct gtgagcttcc
     2581 ttgttggagt cattcagatc cagaaagcat gagcttgttt gatgaatatt ttaatgatga
     2641 ttcaattgaa accaggacta ttgatgatgt tccagttaaa acaagtacag atagtaaaga
     2701 gtattgctgt atgttggagt atccaaaaag attgtataca aaaactaaca aacagaaaag
     2761 tgaactttgt aaatgtatag aaacagttca tcaagattca tgtaatgcct gctttcctca
     2821 gcaggaccag aggaattccc tctccattct tgtcccccat ggggataaag agagttcaga
     2881 caaaaaaaat gctgtaggaa ctgaatggga cattccaaga aatgaaagtt cagatagtgc
     2941 ccttggagat agtgagagtg aagacacagg cccggacata aggagacaag ctggcggtta
     3001 ctgtggaggg gaccaggaag actggacaga agaggatgag ataccttttc ctgggtcaaa
     3061 attgattgaa gtgagtgctg ttcagcccaa cattgccaac tttggaagat ctttgctggg
     3121 tggctactgc tcatcttatg ttcctgactt tgttcttcaa ggaattggaa atgatgagag
     3181 gctccgtcag tgcctggtat cagatttgtc tcatgctgtg cagcatccag tgttagatga
     3241 accaatagca gaagctgtct gtattatagc tgatatggat aaatggactg ttcaagtggc
     3301 cagcagtcag agacgagtaa cagataataa attgggaaag gaggtgttgg tctctagtct
     3361 tgtttccaac ctgcttcatt ccactcttca gctttataaa cataatttat ctccaaactt
     3421 ttgtgtaatg caccttgaag accggttaca ggagttatac ttcaagagca aaatgctgtc
     3481 tgagtacctg aggggacaga tgcgtgttca tgtcaaggag ctaggagtgg ttcttgggat
     3541 tgaatccagt gaccttcctc ttctggctgc ggtagcaagc acccactctc catacgttgc
     3601 tcagatactc ctttaacatg tctagaggct aactttgttt aaagttgaat agaaaccaag
     3661 gagacaggcg ctgtatctgt ggagctgttg ctgttctgtg atgtttgttt tgtgcattac
     3721 gctttaggtg aacgcatcac cctgcgctgc ggtctgtgta gaccaaatga ctttttattt
     3781 ttaactggac atctgagcag tggtagattt ttcaactaag tgaaactaaa tcaaaataat
     3841 tgggggtatg tagaggggtg gaatttgcaa aagccaaagt gtaacttaga attttctgtg
     3901 aatatacagg aatttcatac aaactctata aaatgtcaca actcatgaat agcaatagtt
     3961 gtctcatgat caaatgtcag aaatcttcaa ttcactgatt tttaattttt aattctatgg
     4021 tacagaaatc tacaagacct tgatttgttt gttgttttgc aattcagatc aacttatttc
     4081 tagttattta agtatttttt ttattaaaaa caactgttaa ttatgagaaa ctcagaatga
     4141 gtgaagatgt catgtgccca tcccaagtgt acatatgtat ctattttttt aaaaaagcag
     4201 gggtagaaat acaatattga taaaaatgcc tttttaaaaa aatatttttt catctagtat
     4261 tgtatataat gttgaaatac taccttctga tgatttttct gtttcacgca ttctaaaatg
     4321 tatttaagcc aatctttttg aggctcaagg ttctagattc cctaaggata ctacttttta
     4381 ccatttgttt tctaagaata agctaattct tatcaatatt tacatattaa tttaataaat
     4441 aaaaattaag attaaaaagt gcaccaaagc aatggcaaaa atactgtatt ttttaaatat
     4501 gctcaggtgg ccacaaactt cagtatcgac cattataaac ccatatgagc agaatatttc
     4561 ctaacaatcc tcaatttaca ctagtagaag taatatcttt aaaaactgtt ctttctttaa
     4621 gtgttccttt ctttcaaatg ttgattgctt ttcaaagctt tccccttatc tgtcattgtc
     4681 tttgtatata gtgcagattg ttgcttgtaa gaaaggctaa taaggaacca aactcttgta
     4741 agtaatgtaa ataaaaaggt gggtagatca tgttttcaat atactctact acctcagttt
     4801 acttgaatac tgaattagag cttactctct gcttgtgtgg gctaagatat acataatgct
     4861 agaattaaag ttggtttctg ttttcattga ctaattctaa attgtttagc tcaaaaaaaa
     4921 aaaagagaga aagaaaggaa aaaagaaaga aaagaagaaa ggaaggaaga aagaaagaaa
     4981 gaaagaaaaa catacccccc cccaaaaaaa atcctaccca cgtgttcggt tactgaataa
     5041 ttttattata acatatccat tcttgctatt taaatttttc agtaattaat gaaaaatttc
     5101 tgtggtttat agtcttcaga atcttgaatt tatgtgtctg gttacattta tcttgctctt
     5161 tatgtgtgtt caagagaatt ccaactagaa aagaataaat agaatgtttt aatggaacat
     5221 aaaccccaaa tttagggtat ctacagttgg ccttggttct gtttgttggt tccagttagt
     5281 acctgggtct cccatggatg acttggtgcc aaagggtttt tttatagatg tggagatttt
     5341 gggggttttt gttttgtttt tgatgtcctt gtaacccatt tgttagtgga attgctctgt
     5401 tgtattctgt tgaaattcag tgagtagatt tctgttagaa tttagaatct gggaaagcta
     5461 cgggccattg tacattattt tttgattgtg gctcagaata atatgtatag caggtagata
     5521 atgttttggg atgttttctt gaacatggaa cttttcatag ttctatttga aatctgtcat
     5581 tacttagaaa ttctagtctt taataagtga atggcttgtg cacctaatat tctcaaaact
     5641 cagctttgct ggaaaggtct atagtttctt aaaaactcgc tagtccttat aggattcctg
     5701 agtttgtaat acttttatca tcatattctt tacttactca aagcccaagg aatgagctgc
     5761 tacttcacta cagtgtggct gtgataaatg tgaaaagagt tttggcctgt ttaaaataat
     5821 ttttcaacta cttaatggta cagacaaata tgtgctgcat aataaaaata cctgtttatt
     5881 gttacaggaa attaaaaagg gatcttttat attataggat taaaactaat tttctgtata
     5941 tgttaactaa ttgatttaat tttaagtatc ttgcatttat taatatgtct taattttgaa
     6001 tttgaaaaca tgaagtgcaa taaacatact actacagatt tcattttgtt gcaattggca
     6061 cgcagtgcag atgatcacta acagtttgca taatgcctcc atcggtagct gtcctctgag
     6121 aatgttctgc tttctcttga gttatttaga tgacgaatat atacaatgta catacttgtt
     6181 tgttgttctg aatacatttc tcaaatgtac acctgtatta taataacctc ccagttctag
     6241 gggaaatttg tgcaataaac actcatgtca atttgatggg t
//
