LOCUS       NM_177091               5122 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus fibronectin type III domain containing 7 (Fndc7),
            transcript variant 1, mRNA.
ACCESSION   NM_177091
VERSION     NM_177091.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5122)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5122)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK054241.1, AL671894.20, AK053989.1, AK160805.1 and BG069833.2.
            
            On Oct 1, 2009 this sequence version replaced NM_177091.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK053989.1, BC113188.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AK054241.1         2-87
            87-353              AL671894.20        60554-60820         c
            354-1062            AK053989.1         217-925
            1063-1063           AL671894.20        47429-47429         c
            1064-2515           AK053989.1         927-2378
            2516-5117           AK160805.1         234-2835
            5118-5122           BG069833.2         1-5                 c
FEATURES             Location/Qualifiers
     source          1..5122
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 47.84 cM"
     gene            1..5122
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="fibronectin type III domain containing 7"
                     /db_xref="GeneID:320181"
                     /db_xref="MGI:MGI:2443535"
     exon            1..365
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..2516
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; fibronectin type III domain-containing protein
                     7"
                     /codon_start=1
                     /product="fibronectin type III domain-containing protein 7
                     isoform 1 precursor"
                     /protein_id="NP_796065.2"
                     /db_xref="CCDS:CCDS17769.1"
                     /db_xref="GeneID:320181"
                     /db_xref="MGI:MGI:2443535"
                     /translation="MAGRPEKCFSLIRFTLLCLKMVISSKTAPEIPTIDQAYSKISNS
                     ITVEWTTVPGATSYLLTAEDGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQS
                     QASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENT
                     TNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKA
                     SVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSK
                     SCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSL
                     TQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAW
                     SPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCS
                     SHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCR
                     MGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAG
                     AVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSY
                     SSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDIT
                     NIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR"
     exon            366..384
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            385..639
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            640..900
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1158
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1413
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1671
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1926
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1927..2181
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2182..2442
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2472
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2534
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2535..5122
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3455..3460
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="hexamer: AAGAAA"
     regulatory      3496..3501
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="hexamer: AACAAA"
     polyA_site      3497
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="major polyA site"
     polyA_site      3541
                     /gene="Fndc7"
                     /gene_synonym="E230011A21Rik"
                     /note="major polyA site"
ORIGIN      
        1 attgtacata cttccttgaa accaaggtca caggagcttc tctggcctgc ttggcatgac
       61 tctcctagat tctttttttt tttttttctt ttcagtcttt gcagtacctg tccctgccag
      121 tccccagtgc ccctagttac aggtgagcgc tggtgctctc caaaggagag gcaacttcca
      181 gagtttgttt ccagctttgc ggccacttca ctctacagct ttcagtgctg agcttctggg
      241 agccaaaaag gactcagttc accgctgtgt ttttgtgctg tacgaaggct gcggctaaca
      301 agatggctgg aagacctgag aagtgttttt ctttgattag attcactctc ctctgtctga
      361 aaatggttat ttcatctaaa acagctcctg aaataccaac tattgatcag gcctattcaa
      421 aaatcagcaa tagtatcacc gtagaatgga ctaccgtgcc aggggccaca agttacttgc
      481 tcacagctga agatgggaac acaatcattg agaccacagt ggctaattcc ccagggacgg
      541 tgacaggcct gaaggctgca accttgtacc aaatcaccat cagatccatc agcgcctctg
      601 gacaaagcca ggcatcatct ccaaagcagg caaagacagt gttggctgcc ccagttctgg
      661 aggttagctc tccaagtcca gactcaatcc ttgtgagctg ggacgccgta tacatggcga
      721 tcggattctc cgtgtctgtt atgcgagcca acggcttggg tagaatttgg aaagagaata
      781 ctacaaacac ctccctgacc ttcagcagtc tggatgccgg aactctctac actataaagg
      841 cctacgcgtg gaatgccaat ggaatccccg gggatgactc cacccgcaat cagagaacca
      901 gtcctcgtgc ccctgccaac attcaagtct tctttgacag cggggcccta aaggcgtctg
      961 tttcgtggac cccgacagaa ggagcgttca actacactgt ggtggcatcg agtgattctt
     1021 cccagcgcag ctgcagcacc actctcagct cctgtagcat tagttccttg cagtgtggaa
     1081 cagagtacct gatttctgtc tcagcaaata acgatgctgg gtccagcaag tcctgctctg
     1141 caccaaccct gaagactgtt gcttgtgcac ctggaagggt gatgatccag gaagagcccc
     1201 ctggtcactt gtctgtggct tggtccaatg tggagctggg tgactattat gtggctttcg
     1261 tgaagagtga tgacggcttg gaggtacact gcaatacctc cctcacccag tgcaacttct
     1321 tgtctgagtg tggcttcacg tacttcatta gtgtgtttgc ctataacaag gcagggcaga
     1381 gtcctctggg cgatgtattc aattacacta cagctccgtg ttgtcctaat gacattagcc
     1441 cagtgttggt gtccagtgac agggtggaaa ttgcctggtc tcctgtgcgt ggtgctgaac
     1501 tctatgaaac caaggccata gctgggtata gcattgtgga gtgcaacgac accgctcctg
     1561 cttgcactct ctctgccttg gattgtgaca ccaagtacaa cgtcacagtg tattccttca
     1621 gtgaggtccg aggcagcaat ctgtcatgct cttcccactt tatcaccaca gctccttgca
     1681 gtcctgaaat aaaaaatatt tcgaaggatg cattctccat gatcaatgtg cactggcggt
     1741 cgactaatga aggcgccact tacacggtga cggcccaggg caagaagggg ctgttccagt
     1801 gcagcagcac cggggagacc tgcaggatgg ggggcctgcc ctgcggctcc atgttctctg
     1861 tcactgctgt ggccgagact caggcgggaa agagcctgcc cagctacagc gtgcccctgg
     1921 aaacagtgcc ctgctgtcca gctggtctga cagcagctca ggtcacccag tctataatca
     1981 acgtgagctg gactgctggg gcagtggctc aaacctatgc tgcagtgctg gagtcataca
     2041 tcggacagtc taagtgtcac acccatcaaa accactgcct tctgggatgc atcacatgtg
     2101 gcatcaacta cacggtggcg ttaaaagcca ttagttccac gggactgact gcagattgtg
     2161 cctatcaaag ttactcttct agtgtctgtt gcccactggg ggtcaaatta tataggctgg
     2221 gccctaatgg catccggatc tactggcgag cctccagggg cgctgccaat tatagcaccg
     2281 acctctatgg ttccaaaggc atctttacat gtgccccaca tgccggtcta agtttctgtg
     2341 acatcaccaa catcccctgt ggggacgttt acaccgtgat ggtctcacca gttgctgaaa
     2401 caggactgaa gcttactttc tgcccaaaaa aaatatactc agttacctgt tctggcagta
     2461 ctcttggaat ggtgatttac agagggaaga ggaacgatac agcgagcccc aggtaaatac
     2521 agatactcca caagggtccc tgtgttgtta gtgagcagcc atggaaactc gctattagaa
     2581 cacaatgtac cgtaggatag gcaaagctcc tttgcgcttt aaaggaggaa ctcagactgt
     2641 ttggagagga caaggtcaag tgtgtcgttg gctgcaaaga agttcaagat gagctgtgga
     2701 gaggagggga ctccacagag gaaaggccca gaaagtcccc tggaaggttg ccagactgag
     2761 tcagcacact gtcacagcct ggatgcataa aagccacgct tagcagaaac ttgtttgggg
     2821 gcttcatatc cagacacacc acagaatgtc gcctatccca aagccacgta gcccaggctg
     2881 gccttgaagt ctcagtcctt ctgcctcaac ctcccaacgt gtcgggttac gggcatccac
     2941 cattatgctc catcacaaac tttaatactt cctggccagg ggtctctcaa aagcttccct
     3001 acagcatcct ctccgcagaa gtatggaatt gcacaccctc agtcaagcca tcctccagag
     3061 gacagcattc gcccccaaga caggcctttg ttgaggcctt taagcttgag tctagagcag
     3121 ctgctgctag ggcaactgtg tggtaacaaa cgccttcggc ccaggttccc ggggaagctg
     3181 agctgcctgc agacttcact gagtcagaga gcgccatgtg agcagacatc tgccagagcc
     3241 tttgggaaag cagaagcgta ggtctgtggc tggaaagact gtcatcacgc tctcggagtg
     3301 agcaaagacg tcaggcggag cagcagccaa gggcaaagag tctcagactg tgacaggctg
     3361 acatgcacac acagcctttc agggttcatg gatctcgcag tctgttctct atgctctgcg
     3421 cacattgtaa tggcttcctt ccgcgatccg agagaagaaa acggtggata tataacatca
     3481 atctgttgta cctagaacaa atgtttgtct gtctgatgcc agaaaagtaa ttttaaaata
     3541 gcatgagtat gatttgtgtc acgagttctc aaaggcatgg ctgtagtgtg tgaaagggtg
     3601 gctcagtggt taagagaaca ggctgttctt gcagaagact cgagttccat tccgagccct
     3661 ctcatggcag cttataaaca tctgtaacac tggtttgggg tgagggtggt ggcggtgggg
     3721 gtgggccata ccctctgtct tctggcctct gagagcatca ggcaccaaat ggtgcacacg
     3781 caggaaactt agacacgagg ccagcaagga agagagcgca aacttcctct cctgcatctt
     3841 ctttccatgt atgagggcac atgccggtaa tctcaaccct caggagtctg aggcaggagg
     3901 atcatgaatt caaggccagc ttggcacaca tcctgaaatg tctcaacaaa caaatcaggg
     3961 atgcaaaaac gtttcgctga caaagagatt ttattactat caagtatcca cttttaaaaa
     4021 atttatgttt tattttacat agatgaatgt gctgccagaa tgtatgtctg tgcaccacat
     4081 gggtgcctgt ggagaccgga agaggacatg aaatcccttg ggatgggagt tacaggtggt
     4141 tatgagccgc cttataggca ctgggaactg agctcagggt ctctgcaaga gcagcaggtg
     4201 ctcttaatca atgagccatc tctccagccc ctgtttattt tttatggttt catacacata
     4261 tactttgcat tctgaacact cacccctcca cacacacaca cacatctcta ctacctctgc
     4321 ccgatccccc ccaccctcca ccaatctcgc ttgtgttcct ggatgtttcg tttagtgtcc
     4381 cagaaagatt tgccaggacc atctgtgggg tgtgatgggc tcagcagagg acacccaagt
     4441 aaagaccaca tccctcctct cagaggatcg actgatagcc catgcttcag aggtaaaggg
     4501 tggggtctca taagcccctg gataaagaga tctttcccag agacaagcca gttctaaaag
     4561 tggagttaaa tgtctcaagt acacaaatgg aagggggttg agttttgttc acttaaaaaa
     4621 attttttttt gttttgtttt tgccagtcag aatagtgcac acctttaatg ctagcactca
     4681 ggaggcaaag ataggtggat gtctgagttt aaggctagcc tggtctacct agggaactcc
     4741 aggcccgaaa aagctagcta gtgagaccct gtctcaaaaa aaaaaaatgt ttttagctgg
     4801 gtacagagat gtataccttt aatcccagct cttaggaggc agagtcaggt ggatctccat
     4861 gagttcgagg ccagcctgga ctagacagtg agttacagga cagccagggt tatagagaga
     4921 cctgtctcaa aaacaaacaa caaccaatct agccagtagt gccgcagacc tttgatccca
     4981 gcaatcagga ggcagaggca ggcagatctc tgaaatcgag gctagtctag tctacaaagc
     5041 aaattctagg acaaacaggg ctatataaag aaaccttgtc ttaaaaaaaa taaaataaaa
     5101 taaaaataga acagaacaaa ac
//
