LOCUS       NM_181420               2028 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Mus musculus fructosamine 3 kinase related protein (Fn3krp), mRNA.
ACCESSION   NM_181420
VERSION     NM_181420.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2028)
  AUTHORS   Delplanque,J., Delpierre,G., Opperdoes,F.R. and Van Schaftingen,E.
  TITLE     Tissue distribution and evolution of fructosamine 3-kinase and
            fructosamine 3-kinase-related protein
  JOURNAL   J Biol Chem 279 (45), 46606-46613 (2004)
   PUBMED   15331600
  REMARK    GeneRIF: fructosamine 3-kinase and fructosamine 3-kinase-related
            protein have roles in repairing damage caused by ribose 5-phosphate
REFERENCE   2  (bases 1 to 2028)
  AUTHORS   Collard,F., Wiame,E., Bergans,N., Fortpied,J., Vertommen,D.,
            Vanstapel,F., Delpierre,G. and Van Schaftingen,E.
  TITLE     Fructosamine 3-kinase-related protein and deglycation in human
            erythrocytes
  JOURNAL   Biochem J 382 (Pt 1), 137-143 (2004)
   PUBMED   15137908
REFERENCE   3  (bases 1 to 2028)
  AUTHORS   Collard,F., Delpierre,G., Stroobant,V., Matthijs,G. and Van
            Schaftingen,E.
  TITLE     A mammalian protein homologous to fructosamine-3-kinase is a
            ketosamine-3-kinase acting on psicosamines and ribulosamines but
            not on fructosamines
  JOURNAL   Diabetes 52 (12), 2888-2895 (2003)
   PUBMED   14633848
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663088.10.
            
            On Jul 15, 2009 this sequence version replaced NM_181420.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032265.1, AY360466.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               AL663088.10        110942-111172
            232-383             AL663088.10        114495-114646
            384-475             AL663088.10        115124-115215
            476-558             AL663088.10        116190-116272
            559-681             AL663088.10        118614-118736
            682-2028            AL663088.10        118991-120337
FEATURES             Location/Qualifiers
     source          1..2028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 85.37 cM"
     gene            1..2028
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /note="fructosamine 3 kinase related protein"
                     /db_xref="GeneID:238024"
                     /db_xref="MGI:MGI:2679256"
     exon            1..231
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1020
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /EC_number="2.7.1.172"
                     /note="ortholog of human fructosamine-3-kinase-related
                     protein FN3KRP; FN3K-related protein; protein-psicosamine
                     3-kinase FN3KRP"
                     /codon_start=1
                     /product="ketosamine-3-kinase"
                     /protein_id="NP_852085.2"
                     /db_xref="CCDS:CCDS25775.1"
                     /db_xref="GeneID:238024"
                     /db_xref="MGI:MGI:2679256"
                     /translation="METLLKRELGCSSVKATGHSGGGCISQGQSYDTDKGRVFVKVNS
                     KAEARRMFEGEMASLTAILKTGTVKVPKPIKVVDAPGGGSMLVMEHLDMRYLSSHATK
                     LGTQLADLHLENKRLGERLLKEAGTVGKGGEQAERQYVDQFGFDVVTCCGYLPQVNDW
                     QKNWVEFYARQRIQPQMDMVEKKSGDREALELWSALQLKIPDLFRDLEIVPALLHGDL
                     WGGNVAEDSSGPIIFDPASFYGHSEYELAIAGMFGGFSSSFYSAYHSKIPKTPGFEKR
                     LQLYQLFHYLNHWNHFGSGYRGSSLNIMRNLSK"
     exon            232..383
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     exon            384..475
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     exon            476..558
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     exon            559..681
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     exon            682..2028
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1016..1021
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /note="hexamer: AATGAA"
     polyA_site      1037
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /note="major polyA site"
     regulatory      1961..1966
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /note="hexamer: AATAAT"
     polyA_site      1984
                     /gene="Fn3krp"
                     /gene_synonym="FN3K-RP"
                     /note="major polyA site"
ORIGIN      
        1 aatcccgtca ctggtctgtg tctaccccgc cccgcccctg tacccgcttc tgctccaggc
       61 ctgaactggg tcggctgggg aactgctctc atggagaccc tgcttaagcg ggagctgggc
      121 tgcagctcgg tcaaagctac gggtcactcg ggaggcgggt gcattagcca gggccagagt
      181 tatgacacgg acaaaggacg agtgtttgtg aaagtgaact ccaaggcaga ggctagaaga
      241 atgtttgagg gtgagatggc aagcttaact gccattctga agacgggtac agtcaaggta
      301 cctaagccca tcaaggttgt cgatgcccca ggaggtggga gcatgctcgt gatggagcat
      361 ttggacatgc ggtatctgag cagtcatgcc accaagcttg ggacccagct tgcagatcta
      421 caccttgaga acaagaggct tggagagagg ctgctaaagg aggctggcac tgtggggaaa
      481 ggaggtgaac aggcagagcg gcagtatgtg gaccagtttg ggtttgatgt agtgacatgc
      541 tgtggatacc tcccccaggt aaatgactgg cagaagaatt gggtcgaatt ctatgccagg
      601 cagcgcattc agccccagat ggacatggtg gagaagaagt ctggggaccg ggaagctctt
      661 gagctgtggt ctgctctgca gttgaagatt cctgacctgt tccgtgatct ggaaattgtg
      721 cccgccttac tccatggaga cctctgggga gggaatgtag cagaagattc ctctgggccc
      781 atcatttttg acccagcatc cttctatgga cactcagaat atgagctggc aatagcgggc
      841 atgtttggcg gcttcagtag ctccttttac tctgcatacc acagcaaaat ccctaaaacc
      901 ccaggatttg agaagcgctt acagttgtat cagctctttc actatctgaa ccactggaat
      961 cattttggat ctgggtacag gggatcctct ctaaacataa tgaggaatct cagcaaatga
     1021 actggcttcc caccagaggg aagagtctct tgtgggtgtg ttgggtctcc taataagatg
     1081 actctccatc tagatcaagt cttagcatca tacgcatcac tgtgaacgga gggaagtgcg
     1141 tggggtcagg tgacctgact ccaacgattt ggtcaaggag gttatgattc ttcatagtca
     1201 ctctcctcat gaatccttcc catttattcc atggtaggac ttgcttaaga tcccttgttt
     1261 ctttctcttt ttctcctccc ttttttccta ttctctcata tattacatcc tgactgcagt
     1321 ttcccctccc tctctcctca gaatctcctc tgccacgccc cccagggaca tcaaccaagc
     1381 acagtataac aagctacaat aagccaggca cataacatca catccaggct ggataaggca
     1441 acccaggagg agggaacggg aacgggaacg ggtcgcacag taggcaagag tcagggacac
     1501 cctccattcc cactgttagg attcccacac gaacaccaag ctactcagcc ataacatatg
     1561 cagaggactt gctcagactc ctacaggctc ctgatcactg caagccccca gtaccggtca
     1621 gttgattctg tgggctgtaa actgtgaagt atgggttctc tcagaggaaa ggttatgaaa
     1681 ttctgttgtg tgcatagtaa gactgcctgg ctaaattagg cctcactggc gatagaacag
     1741 acttactgaa gtttaggtat agtgagccac actccactgc caaggtagag aactgtgagt
     1801 gactgttggt gtggtgaagg gtgttgacca tgcagggaag tggccaatgt gcccacttcc
     1861 catctcttcc ttgcgcattg tcagcatttc tgagtgattc acagtgatgt tttatgatgg
     1921 ttagacttct ggacatggac tcatcttgtg agaagatttg aataatgacc aattctaaaa
     1981 tcaataacgt tccatttgct tatgtagcac ttctggaccc tgctataa
//
