LOCUS       NM_001357994            3374 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus FLYWCH-type zinc finger 1 (Flywch1), transcript
            variant 2, mRNA.
ACCESSION   NM_001357994
VERSION     NM_001357994.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3374)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3374)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3374)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (bases 1 to 3374)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122821.4 and AI849618.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.3277.1,
                                           SRR1660817.146453.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AC122821.4         91910-92097
            189-531             AC122821.4         100194-100536
            532-960             AC122821.4         100918-101346
            961-1470            AC122821.4         102396-102905
            1471-1734           AC122821.4         103045-103308
            1735-1998           AC122821.4         106702-106965
            1999-2289           AC122821.4         107568-107858
            2290-3313           AC122821.4         109649-110672
            3314-3374           AI849618.1         1-61                c
FEATURES             Location/Qualifiers
     source          1..3374
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.04 cM"
     gene            1..3374
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /note="FLYWCH-type zinc finger 1"
                     /db_xref="GeneID:224613"
                     /db_xref="MGI:MGI:2442638"
     exon            1..188
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            189..531
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..2312
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /note="isoform 1 is encoded by transcript variant 2;
                     FLYWCH-type zinc finger-containing protein 1"
                     /codon_start=1
                     /product="FLYWCH-type zinc finger-containing protein 1
                     isoform 1"
                     /protein_id="NP_001344923.1"
                     /db_xref="GeneID:224613"
                     /db_xref="MGI:MGI:2442638"
                     /translation="MPLPEPSEQDCESLRAGQEPSVGARKPQESSNLVPARDKERPKP
                     TDVASQETSSTATLPNNTLQVAPVKKQGRIIHRKRSRVDAVPPQPLEFLKTPFGGRLL
                     VHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTEMRDHCHPPEKEGLDRK
                     KRHRGRPPSSALPEGAEVQEDEVSLWLYPVEPEPTPQPSIETPEEEQGYRSLALQSLP
                     PKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGGKVYWTCREHAVHGCRS
                     RAITQGQRVTVMRSHCHSPDIEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDSLL
                     QGVDSLFYRRGQGTLTLSRSKSKSKSKSRSKSKSKSRSRSRKRAKKQQESSQEPPEED
                     QDVDPRGPEFLKTPLGGNFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGR
                     QVTVMRSHCHPPDLLGLETLRQREKRPGPSQWDGPEGPEFLKTPLGGSFLVYESFLYR
                     REKATGDKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGGLEALRQRENFPN
                     LTHWEGPEPLQPLEFLRTSLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRA
                     ITQGRRVMVMRSHCHPPDLAGLEALRQREKAPSAAKKKKKKKKKKKGKSKSKN"
     exon            532..960
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1470
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1734
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1998
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2289
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..3358
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3331..3336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /note="hexamer: AATAAA"
     polyA_site      3356
                     /gene="Flywch1"
                     /gene_synonym="E030034P13Rik; mKIAA1552"
                     /note="major polyA site"
ORIGIN      
        1 aggcgtctcg cgggggcgcg cgcgcgggca cgggctcgct ccccaggggg cagttggcgg
       61 cgggagcggg cggcggggtc gtggttccta gagcagcccc ggctgctagg ccggcgcctg
      121 cgttggcgga cactcacacg aaggatcggg tggctcagcc gccggagagg cagggcccgc
      181 tgccgtcgga cggaggctct ggactcccac attctgaaga gagacccatc tgccagaggg
      241 ctgaaggtgg ccttgagggc catgctctgg gtctcaggat gcccctgcct gagcccagtg
      301 agcaggactg tgagagcctg agagctggcc aggagccatc tgttggagcc aggaagcctc
      361 aagagtcctc caatctggtc ccggccaggg ataaagagag acccaagccg acagatgtcg
      421 cgtcccagga gacgtctagc actgcaaccc taccgaacaa tactctccag gttgcaccag
      481 tcaagaagca aggacggata attcaccgga aacgtagtag ggtagatgca gttcctcccc
      541 agcctctgga gttcctgaag accccatttg ggggccgcct tctggtgcac aagtcattcc
      601 tgtacaagca agagaaggct gtgggggaca aggtgtactg gaaatgccgc cagcactcag
      661 agctaagctg ccggggacgg gccatcaccc gtggctttcg agtcacagag atgcgggacc
      721 actgtcaccc acctgagaag gagggcctgg acaggaaaaa gcgccacagg ggaaggccgc
      781 ccagctcagc cctgcctgag ggcgctgaag tccaagaaga tgaagtgagc ctatggttgt
      841 accctgtgga gccagaacct actcctcagc caagcattga aaccccagag gaggagcagg
      901 ggtaccggtc cctggcactg cagagcctgc ctcccaagaa acgccctaca ccaggagtgg
      961 tacggtatcg gcctcttgag ttcctgaaga cttgctatgg gggtaccttc ctggttcacc
     1021 agtccttcct ctacaagcgg gaaaagacgg taggaggcaa ggtgtactgg acctgccggg
     1081 aacatgcagt ccatggctgc cgtagccgag ccatcaccca gggccagcgt gtgacagtga
     1141 tgcgcagcca ttgccactca cctgacatag aaggcttgca ggcccggcga cagcaggaga
     1201 agaccataaa gaagatacag gcaaggcgaa ttggggctgg ggacttggag gattgcgatg
     1261 acatagagga ctcactgctg caaggagtgg acagcctgtt ctaccgaaga gggcagggca
     1321 cactgactct cagtaggtcc aagtccaagt ccaagtccaa atccaggtcc aagtccaagt
     1381 ccaagtccag gtccaggtct agaaaacgag caaagaagca gcaggaatcc tcgcaggagc
     1441 cccccgagga ggaccaggat gtagacccca gaggcccaga gttcctaaaa acccctctag
     1501 ggggcaactt cctggtgtat gagtccttcc tctacagacg ggagaaagtg gctggtgaga
     1561 aggtgtactg gacctgccgg gaccaggcac gcatgggttg tcgcagccgc gccatcactc
     1621 agggcaggca ggtgactgtg atgcgaagcc actgtcatcc accagacctg ttaggattgg
     1681 agactctgag gcagcgggag aaacgcccag gcccctctca gtgggatggc ccagaagggc
     1741 ctgagttcct aaagacccct ctaggaggca gcttcctggt atatgagtcc ttcctctaca
     1801 gacgggaaaa agcaactggt gataaggtgt actggacctg ccgggaccag gcacgcatgg
     1861 gctgtcgcag ccgagctatc acacagggcc agcgggtgat ggtcatgcgc aggcactgcc
     1921 acccaccgga catgggtggc ctggaagccc ttcggcagag ggagaacttc cctaacctga
     1981 cccactggga aggcccagag cccctgcagc cactggagtt cctgcggaca tcccttggag
     2041 gccgcttcct ggtgtatgag tccttcctgt acaggaagga gaaggctgct ggtgagaaag
     2101 tgtactggat gtgtcgagac caggctcggc tgggctgccg cagccgagcc atcacccagg
     2161 gccggcgggt catggtgatg cggagccact gccacccacc tgacctggct ggcctggagg
     2221 ccctgcggca gcgggagaag gcccccagtg cagccaagaa gaaaaagaag aagaagaaga
     2281 agaagaaagg aaaatcaaag agcaaaaact gagcagccag tcctgctgaa gtgagtcttc
     2341 tctggagcaa cagaggagca gctggcaccc caaatgcttc ccatccttgc aggcgtttcc
     2401 catccttcag atgcacttga tgacaactct tccaaagcac ccaggactgt cacatttcct
     2461 cagaggtctc ccaggaggag tgcttggact ttgggtggta accaagctgg atgggtggcc
     2521 tgcaggcctg tcccatgctg ctcttaccat cctgacctta gacagctgtg gagaactgtg
     2581 tctggatgat atacctctgc cctgctctgc tctccaggcc tcagcaccat ctgctttcag
     2641 agcacactgc cttgctcaga gctttccagt gggcgtgatc ccgtgtgcgc tccatgaagt
     2701 tcagcaaaat gcagtcaccc caagccagga tatgtgcagg aacttcttgc caccctctga
     2761 agacagtgca agtcacagca gggtttgttt tgctttgtgg catcttttag gggcaggtgt
     2821 gaggcctgcc tgctctttag tctcttgctg cttgctaagg ctcacccagc tctgactgtg
     2881 gcagagcgga acaggctaaa ggcttcgctc tacctccctg gcagacttgg caccctgcgt
     2941 tctttcccaa cttaaacctg tgtccacagt tcttgggagc cagcccagat gtcaggagga
     3001 ggtgacacca tgtaggcatg ctctagtggc agcggcacca ctgagggttg ctcacctggt
     3061 gtcgcatgat gcaccaggtc agttagatgg catcaaagcc acctcctgta gaagagttta
     3121 gcaggactca ggagccatgc cagcagtggc actctaatgt ccccaggaac ggcagaattt
     3181 cctgcgtgct gcaccctggc cagagctgtc ctcatcatgt catagagctg catgctcctc
     3241 tcccttagca aacaagccgt ggaacagcca cccctgtggg atagtaatgg cctggtgcct
     3301 gccgctgtct tctgctcatc tgattccctc aataaaccct gtgtagtctc atggtacaaa
     3361 aaaaaaaaaa aaaa
//
