LOCUS       NM_022009               4071 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus flightless I actin binding protein (Flii), transcript
            variant 1, mRNA.
ACCESSION   NM_022009 XM_916455 XM_924269
VERSION     NM_022009.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4071)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4071)
  AUTHORS   Gonuguntla,S., Humphrey,R.K., Gorantla,A., Hao,E. and Jhala,U.S.
  TITLE     Stress-induced pseudokinase TRB3 augments IL1beta signaling by
            interacting with Flightless homolog 1
  JOURNAL   J Biol Chem 299 (8), 104803 (2023)
   PUBMED   37172723
  REMARK    GeneRIF: Stress-induced pseudokinase TRB3 augments IL1beta
            signaling by interacting with Flightless homolog 1.
REFERENCE   3  (bases 1 to 4071)
  AUTHORS   Kuwabara,Y., York,A.J., Lin,S.C., Sargent,M.A., Grimes,K.M.,
            Pirruccello,J.P. and Molkentin,J.D.
  TITLE     A human FLII gene variant alters sarcomeric actin thin filament
            length and predisposes to cardiomyopathy
  JOURNAL   Proc Natl Acad Sci U S A 120 (19), e2213696120 (2023)
   PUBMED   37126682
REFERENCE   4  (bases 1 to 4071)
  AUTHORS   Mills,S.J., Ahangar,P., Thomas,H.M., Hofma,B.R., Murray,R.Z. and
            Cowin,A.J.
  TITLE     Flightless I Negatively Regulates Macrophage Surface TLR4, Delays
            Early Inflammation, and Impedes Wound Healing
  JOURNAL   Cells 11 (14), 2192 (2022)
   PUBMED   35883634
  REMARK    GeneRIF: Flightless I Negatively Regulates Macrophage Surface TLR4,
            Delays Early Inflammation, and Impedes Wound Healing.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4071)
  AUTHORS   Kopecki,Z. and Cowin,A.J.
  TITLE     Flightless I: an actin-remodelling protein and an important
            negative regulator of wound repair
  JOURNAL   Int J Biochem Cell Biol 40 (8), 1415-1419 (2008)
   PUBMED   17526423
  REMARK    Review article
REFERENCE   6  (bases 1 to 4071)
  AUTHORS   Campbell,H.D., Fountain,S., McLennan,I.S., Berven,L.A.,
            Crouch,M.F., Davy,D.A., Hooper,J.A., Waterford,K., Chen,K.S.,
            Lupski,J.R., Ledermann,B., Young,I.G. and Matthaei,K.I.
  TITLE     Fliih, a gelsolin-related cytoskeletal regulator essential for
            early mammalian embryonic development
  JOURNAL   Mol Cell Biol 22 (10), 3518-3526 (2002)
   PUBMED   11971982
  REMARK    GeneRIF: performs an essential function in early embryonic
            development
REFERENCE   7  (bases 1 to 4071)
  AUTHORS   Davy,D.A., Campbell,H.D., Fountain,S., de Jong,D. and Crouch,M.F.
  TITLE     The flightless I protein colocalizes with actin- and
            microtubule-based structures in motile Swiss 3T3 fibroblasts:
            evidence for the involvement of PI 3-kinase and Ras-related small
            GTPases
  JOURNAL   J Cell Sci 114 (Pt 3), 549-562 (2001)
   PUBMED   11171324
REFERENCE   8  (bases 1 to 4071)
  AUTHORS   Davy,D.A., Ball,E.E., Matthaei,K.I., Campbell,H.D. and Crouch,M.F.
  TITLE     The flightless I protein localizes to actin-based structures during
            embryonic development
  JOURNAL   Immunol Cell Biol 78 (4), 423-429 (2000)
   PUBMED   10947868
REFERENCE   9  (bases 1 to 4071)
  AUTHORS   Campbell,H.D., Fountain,S., Young,I.G., Weitz,S., Lichter,P. and
            Hoheisel,J.D.
  TITLE     Fliih, the murine homologue of the Drosophila melanogaster
            flightless I gene: nucleotide sequence, chromosomal mapping and
            overlap with Llglh
  JOURNAL   DNA Seq 11 (1-2), 29-40 (2000)
   PUBMED   10902907
REFERENCE   10 (bases 1 to 4071)
  AUTHORS   Probst,F.J., Chen,K.S., Zhao,Q., Wang,A., Friedman,T.B.,
            Lupski,J.R. and Camper,S.A.
  TITLE     A physical map of the mouse shaker-2 region contains many of the
            genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2)
  JOURNAL   Genomics 55 (3), 348-352 (1999)
   PUBMED   10049592
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BB857715.1, AK014400.1,
            AK049365.1 and AW047188.1.
            
            On Oct 9, 2014 this sequence version replaced NM_022009.1.
            
            Summary: This gene encodes a protein with gelsolin-like repeats and
            an N-terminal leucine-rich repeat domain. The protein is similar to
            a Drosophila protein involved in early embryogenesis and the
            structural organization of indirect flight muscle. This protein may
            act as an actin-remodelling protein as well as a transcriptional
            coactivator. Homozygous knockout mice show embryonic lethality.
            This protein may act to regulate wound repair. Alternative splicing
            results in multiple transcript variants encoding different
            isoforms. [provided by RefSeq, Oct 2014].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027744.1, AF287264.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BB857715.1         3-44
            43-216              AK014400.1         2-175
            217-947             AK049365.1         177-907
            948-2309            AK014400.1         907-2268
            2310-3440           AK049365.1         2270-3400
            3441-3496           AK014400.1         3400-3455
            3497-4054           AK049365.1         3457-4014
            4055-4071           AW047188.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..4071
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.81 cM"
     gene            1..4071
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /note="flightless I actin binding protein"
                     /db_xref="GeneID:14248"
                     /db_xref="MGI:MGI:1342286"
     exon            1..137
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..3890
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein flightless-1 homolog; cytoskeletal
                     actin-modulating protein; flightless I homolog"
                     /codon_start=1
                     /product="protein flightless-1 homolog isoform 1"
                     /protein_id="NP_071292.1"
                     /db_xref="CCDS:CCDS24795.1"
                     /db_xref="GeneID:14248"
                     /db_xref="MGI:MGI:1342286"
                     /translation="MEATGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTG
                     LCYLPEELAALQKLEHLSVSHNHLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFK
                     LDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNGIDSIPNQLFINLTDLLYLDLSE
                     NRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMMALQTLHLRNTQRTQSNLPTS
                     LEGLSNLSDVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIAELSLCIDQWVHLETLNL
                     SRNQLTSLPSAICKLTKLKKLYLNSNKLDFDGLPSGIGKLTSLEEFMAANNNLELIPE
                     SLCRCPKLKKLVLNKNRLVTLPEAIHFLTEIQVLDVRENPSLVMPPKPADRTAEWYNI
                     DFSLQNQLRLAGASPATVAAAAAVGSGSKDPLARKMRLRRRKDSAQDVQAKQVLKGMS
                     DVAQEKNKNQEESIDARAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIEN
                     FVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAV
                     NLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRV
                     YGKKNIKLEPVPLKGSSLDPRFVFLLDQGLDIYVWRGAQATLSNTTKARLFAEKINKN
                     ERKGKAEITLLVQGQEPPGFWDVLGGEPSEIKNHVPDDFWPPQPKLYKVGLGLGYLEL
                     PQINYKLSVEHKKRPKVELMPGMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRA
                     AALKLGQELCGMLHRPRHTVVSRSLEGTEAQVFKAKFKNWDDVLTVDYTRNAEAVLQG
                     QGLSGKVKRDTEKTDQMKADLTALFLPRQPPMPLAEAEQLMEEWNEDLDGMEGFVLEG
                     RKFTRLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKTEDKEGKASAEAREGEEAAAE
                     AEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENP
                     KFLSHFKRKFIIHRGKRKVTQGTLQPTLYQIRTNGSALCTRCIQINTDSSLLNSEFCF
                     ILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDASYSKQVINEGEEPENFF
                     WVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQ
                     EVYMWVGTQTSQVEIKLSLKACQVYIQHTRSKEHERPRRLRLVRKGNEQRAFTRCFHA
                     WSTFRQAPA"
     exon            138..248
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            249..320
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            321..401
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            402..487
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            488..649
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            650..753
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            754..929
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1087
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1172
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1320
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1457
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1670
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1850
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1933
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            1934..2008
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..2092
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2093..2264
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2369
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2370..2561
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2562..2750
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2890
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            2891..3131
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3132..3286
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3287..3347
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3476
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3477..3583
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3584..3689
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3690..3755
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..4060
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4030..4035
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /note="hexamer: ATTAAA"
     polyA_site      4060
                     /gene="Flii"
                     /gene_synonym="3632430F08Rik; Fliih"
                     /note="major polyA site"
ORIGIN      
        1 ggggccggcg ctgacccagc ccgcggctct cggccgcccc gcgtcctccc tgcccgtaag
       61 agagctgcgc caccatggag gccaccgggg tgctgccgtt cgtgcgcggc gtggacctca
      121 gcggcaacga cttcaagggt ggctacttcc ctgagaatgt taaggctatg accagcctgc
      181 gatggctaaa gctgaatcgc acaggcctct gctacctgcc tgaagaactt gcggctctgc
      241 agaagctgga gcacctgtct gtgagccaca accatctgac cacgcttcac ggcgaactgt
      301 ctagcctgcc ttcgcttcgg gccattgtag ctcgggccaa cagcctgaag aattccggag
      361 tccctgatga catcttcaag ctggatgatc tctctgttct ggacttgagc cataaccagt
      421 tgacagaatg cccacgggag ctggagaatg ccaagaacat gctggtgctc aacctcagcc
      481 acaacggcat cgactccatc cccaaccagc tgttcatcaa ccttacggac ttgctgtacc
      541 tggacctcag tgaaaaccgc ctagagagcc ttccccctca aatgcgccgc ctcgtgcacc
      601 ttcagacact ggtgctgaat ggaaacccgc tgctacatgc acagctccgg cagctcccag
      661 ccatgatggc cctacagacc ctgcatctga ggaacactca acgcacccag agcaacctcc
      721 ccaccagcct ggagggcctg agcaaccttt cagatgtgga cctgtcgtgc aatgacttga
      781 caagggtgcc ggagtgcctg tacaccctcc ccagcctgcg ccgcctcaac ctcagtagca
      841 accagattgc agagctgtcc ctgtgcatcg accagtgggt gcacctggag accttgaatc
      901 tgtcccggaa ccagctcacc tccctgcctt cagccatctg caagctcacc aagctgaaga
      961 agctgtacct caactccaac aagctggact ttgatgggct gccttctggc atcggcaagc
     1021 tcaccagcct ggaggaattc atggctgcca acaacaacct agaactgatt cctgaaagtc
     1081 tctgcaggtg cccaaaactg aagaaactcg tcctgaataa gaaccgcctg gtgacccttc
     1141 ctgaggccat ccacttcctg acagagatcc aggtcctgga tgttcgagaa aaccccagct
     1201 tggtcatgcc gcccaagcct gctgaccgca ccgccgagtg gtacaacatt gacttctcgc
     1261 tacagaacca gctgaggctg gcgggcgcct ccccggccac agtggctgct gctgcagctg
     1321 tagggagcgg gtccaaggac cccttggctc gcaagatgcg gctacggagg cgcaaggact
     1381 cagcacagga tgtccaggcc aagcaagtgc taaagggcat gtcagatgtt gcccaggaga
     1441 aaaacaaaaa ccaagaggaa agcatagatg cccgggcacc agggggaaag gtacgacgct
     1501 gggaccaggg cctggagaag ccacgccttg actactcgga gttctttacg gaggatgtgg
     1561 gccagctgcc tggtttgacc atctggcaaa ttgagaactt tgtgcctgtt ctggtggaag
     1621 aagccttcca tggcaagttc tacgaggctg actgctacat tgtgctcaag accttcctgg
     1681 atgacagcgg ctccctgaac tgggagatct actactggat tggtggggag gccacacttg
     1741 acaagaaagc ctgttccgcc attcatgcag tcaatctgcg caactacctg ggtgctgagt
     1801 gccgtactgt tcgagaggag atgggtgacg agagtgagga gttcctgcag gtgtttgaca
     1861 atgacatctc ctacattgaa ggcggaacag ccagtggctt ctatactgtg gaagatacac
     1921 actatgttac caggatgtac cgtgtatatg ggaaaaagaa catcaaattg gagcctgtgc
     1981 ccctcaaagg gtcctcacta gatccaaggt ttgtgtttct cctggaccaa gggctggaca
     2041 tttatgtgtg gcggggggcc caggccacac tgagtaacac gactaaggcc aggctctttg
     2101 cagagaaaat aaacaagaat gagcggaaag ggaaggcgga aatcacactc ctggtgcagg
     2161 gccaagagcc cccagggttc tgggatgtgc tgggtggaga gccttctgag atcaagaatc
     2221 atgtgcctga tgacttttgg ccaccccagc ccaagctata caaggtgggc ctgggtctgg
     2281 gctacttgga gcttccgcag atcaactaca agctctcagt ggaacacaaa aaacggccca
     2341 aggtggagct gatgccagga atgaggctgc tgcagagcct actggacaca cgatgcgtgt
     2401 acatcctgga ctgctggtct gatgtattca tctggctggg ccgcaagtcc ccacgcctag
     2461 tgcgtgcagc agcactcaaa cttggccagg agctatgtgg gatgctacac cggccacgac
     2521 atacagtggt cagccgcagc ctggagggca ccgaggccca ggtgttcaag gccaagttca
     2581 agaactggga cgatgtgttg acagtggact acacacggaa tgcagaggct gtgcttcagg
     2641 gccagggcct ctctgggaag gtgaagcgtg acactgagaa gacagaccag atgaaggctg
     2701 acctcactgc actcttccta cctcggcagc cccccatgcc cctggctgag gcagagcagc
     2761 tgatggagga gtggaatgag gacctggatg gcatggaggg cttcgtgctg gagggccgca
     2821 agttcactcg actgccagag gaggagtttg gccacttcta cacacaggac tgctatgtct
     2881 tcctctgcag gtactgggta cctgtggagt acgaggagga agagaagaca gaagacaagg
     2941 aggggaaggc ctcggcagag gccagagaag gggaggaagc agcagcggag gcagaggaga
     3001 agcagccaga ggaggacttt cagtgcatcg tttacttctg gcagggccgg gaggcctcca
     3061 acatgggctg gctgaccttc acattcagtc ttcagaagaa gtttgagagc ctcttccctg
     3121 gcaagctgga ggtagtacgt atgacacagc agcaggagaa ccccaagttc ctatcccatt
     3181 tcaaaagaaa gttcatcatt caccgaggca agaggaaggt gacccagggt actcttcagc
     3241 cgaccctcta tcagatccgc accaacggca gtgccctctg cacccggtgc atccagatta
     3301 acactgactc cagccttctc aactctgagt tctgcttcat cctcaaggtc ccctttgaaa
     3361 gcgaggacaa ccaaggcatt gtgtatgcct gggtaggtcg ggcatcagac cccgacgaag
     3421 ccaagctggc agaggacatc ctgaacacta tgtttgatgc atcctacagc aaacaggtca
     3481 tcaatgaagg cgaggagcca gagaacttct tctgggtagg cattggtgca cagaaaccct
     3541 atgatgacga tgcggagtac atgaagcaca cgaggctctt caggtgctcc aatgagaagg
     3601 gttacttcgc agtgactgag aaatgctctg acttttgcca agatgacctg gcagacgatg
     3661 acatcatgct gctagacaat ggccaagaag tctacatgtg ggttgggacc cagacaagcc
     3721 aagtggagat caaactgagt ctgaaggctt gccaggtata catccagcac acacgctcta
     3781 aagaacatga gcggccacgt cgcctgcgcc tggtccgcaa aggtaatgag cagcgcgcct
     3841 tcacccgctg cttccacgcc tggagcacgt tccgccaagc cccagcctaa gcagtaccta
     3901 tgacctcaga ctccagtgag gaagaggagg actcctcgta cctgcttcag ctagccacag
     3961 cctgcaagca gcacacagcc ccaagcccca ccagtgtgtc cacatgtgtg cagatgtagt
     4021 ttaaaagata ttaaatgctt ttattttcaa tattaaaaaa aaaaaaaaaa a
//
