LOCUS       NM_175370               1575 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus flagellum associated containing coiled-coil domains 1
            (Flacc1), transcript variant 3, mRNA.
ACCESSION   NM_175370
VERSION     NM_175370.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Chotiner,J.Y., Leu,N.A. and Wang,P.J.
  TITLE     FLACC1 is testis-specific but dispensable for fertility in mice
  JOURNAL   Mol Reprod Dev 87 (12), 1199-1201 (2020)
   PUBMED   33156557
  REMARK    GeneRIF: FLACC1 is testis-specific but dispensable for fertility in
            mice.
            GeneRIF: FLACC1 is dispensable for viability and fertility in
            mouse.
REFERENCE   2  (bases 1 to 1575)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   3  (bases 1 to 1575)
  AUTHORS   Choi,E. and Cho,C.
  TITLE     Expression of a sperm flagellum component encoded by the Als2cr12
            gene
  JOURNAL   Gene Expr Patterns 11 (5-6), 327-333 (2011)
   PUBMED   21402173
  REMARK    GeneRIF: the expression of the Als2cr12 gene at the
            transcriptional, protein and cellular levels.
REFERENCE   4  (bases 1 to 1575)
  AUTHORS   Choi,E., Lee,J., Oh,J., Park,I., Han,C., Yi,C., Kim,D.H., Cho,B.N.,
            Eddy,E.M. and Cho,C.
  TITLE     Integrative characterization of germ cell-specific genes from mouse
            spermatocyte UniGene library
  JOURNAL   BMC Genomics 8, 256 (2007)
   PUBMED   17662146
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133373.1 and AK077190.1.
            
            On Jul 16, 2015 this sequence version replaced NM_175370.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077190.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                AK133373.1         1-34
            35-1575             AK077190.1         3-1543
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 29.15 cM"
     gene            1..1575
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /note="flagellum associated containing coiled-coil domains
                     1"
                     /db_xref="GeneID:108812"
                     /db_xref="MGI:MGI:1918359"
     exon            1..88
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            89..233
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..1272
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /note="isoform b is encoded by transcript variant 3;
                     amyotrophic lateral sclerosis 2 chromosomal region
                     candidate gene 12 protein homolog; amyotrophic lateral
                     sclerosis 2 (juvenile) chromosome region, candidate 12;
                     amyotrophic lateral sclerosis 2 chromosome region 12;
                     flagellum-associated coiled-coil domain-containing protein
                     1"
                     /codon_start=1
                     /product="flagellum-associated coiled-coil
                     domain-containing protein 1 isoform b"
                     /protein_id="NP_780579.1"
                     /db_xref="CCDS:CCDS35581.1"
                     /db_xref="GeneID:108812"
                     /db_xref="MGI:MGI:1918359"
                     /translation="MDPNPFIYCTCCDCCKLGQPKLIKTPYPLPKHPTGKFKPVLPPP
                     ISKEHNSLLSQPGKSTVSPRDKVQSGNTESSKAPSEVIQVSPGYTLIRNREQISVTLG
                     DEMFNRKKHLESDVLSKVKFSRTDIISDLQEQIAELMAIIEQMNRDQQSALKLLSKDL
                     DLRCSNMKQKFETESRELKETHREELERLENNYKEALKAEKALAEEKLDKMSKEYKYL
                     KSMFHVFQDSIYEEMEDKWLRRKAEWEKDEKMEREKILLQQKCRIIKKFELQSEEKKK
                     KMNESISAVSDNFAREKEELLRQHDEDILQIQELRKSKEILEAELRAQATVLETLNTN
                     LFQCQKELERQKTIAANLEKLFQTKLAEAEEKHKYNIKTPTEENNCLRC"
     exon            234..311
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            312..357
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            358..491
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            492..585
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            586..647
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            648..745
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            746..798
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            799..898
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1002
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1065
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1155
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1265
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1575
                     /gene="Flacc1"
                     /gene_synonym="4933405P16Rik; 4933425F06Rik; Als2cr12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gataaaagaa acaaaccatc ctggggcaca agtcaggctc agtcaaagga ctagctagag
       61 ggtgaattcc tcctcaaggg actttcagga gcccctggcc tagcaagact gccttgtacc
      121 atggacccca atcctttcat ctactgtacc tgctgtgact gctgcaaatt gggacaacca
      181 aagctaatca agacccctta tccacttcca aagcacccca cggggaagtt taagccagtt
      241 ttacctccac caatttcaaa agaacacaac tcactcctgt cccaaccagg aaaatctact
      301 gtttccccaa gggacaaggt ccagtcagga aacacagaga gcagcaaagc accttctgaa
      361 gtgattcaag tgtcacctgg ctatacactc attcgaaatc gagaacagat atcagtcacc
      421 ttgggagatg agatgttcaa caggaaaaag cacttggaat cagatgtctt gagcaaagtc
      481 aaattttcca ggactgatat catttctgac cttcaggagc aaattgctga gttgatggca
      541 ataatagaac agatgaacag agaccagcag tctgccctga aactgctctc caaagatctg
      601 gatctccgct gttccaacat gaagcagaag tttgaaaccg agagcaggga actcaaagag
      661 actcacagag aggagctcga gaggttagag aacaactaca aggaggccct gaaggcagaa
      721 aaggccttgg ccgaagagaa actagataag atgagcaagg aatataagta tctgaagagt
      781 atgttccatg tgtttcagga tagcatttac gaggaaatgg aagacaagtg gctgagacga
      841 aaggccgaat gggagaaaga tgagaagatg gagcgggaaa agatcctgct acaacaaaaa
      901 tgtagaataa taaaaaagtt tgagttacag tcggaagaaa aaaagaagaa aatgaatgag
      961 tccatcagtg ctgtttctga taacttcgct cgagagaaag aggagctcct aagacaacat
     1021 gatgaagaca tcctgcaaat acaggagctg agaaaatcca aagagatctt ggaggctgag
     1081 ttgcgggcac aagctactgt tctggagacc ctgaacacaa accttttcca atgccagaaa
     1141 gaactcgaga gacagaaaac tattgcggca aatctagaga aattgttcca gacaaagctt
     1201 gctgaagctg aagaaaagca taagtacaac ataaagaccc cgacagaaga aaataactgc
     1261 ctcagatgtt aaccacaacc acatatgagg aaacttcaga agtttctgag aagtcctcat
     1321 ctgccagtcc caacatgtat gagtctgacg ttcctgaaca caacagcaac aaaaagcaag
     1381 catcgtaggt aactaactgc tcctggggct gagcgacact gccctgggag gaagctacgg
     1441 actcttctgg agagacgcac gggaaggctg agctcttgag ttgttctgta cttttgtcat
     1501 ttttcacaat ttgctttctt ccaatggata gaaatatttg aattcttatc ctaattatat
     1561 cttggctctc cattg
//
