LOCUS       NM_001166368             634 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus FK506 binding protein 2 (Fkbp2), transcript variant 2,
            mRNA.
ACCESSION   NM_001166368
VERSION     NM_001166368.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   2  (bases 1 to 634)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   3  (bases 1 to 634)
  AUTHORS   Walensky,L.D., Gascard,P., Fields,M.E., Blackshaw,S., Conboy,J.G.,
            Mohandas,N. and Snyder,S.H.
  TITLE     The 13-kD FK506 binding protein, FKBP13, interacts with a novel
            homologue of the erythrocyte membrane cytoskeletal protein 4.1
  JOURNAL   J Cell Biol 141 (1), 143-153 (1998)
   PUBMED   9531554
REFERENCE   4  (bases 1 to 634)
  AUTHORS   Poon,M., Marx,S.O., Gallo,R., Badimon,J.J., Taubman,M.B. and
            Marks,A.R.
  TITLE     Rapamycin inhibits vascular smooth muscle cell migration
  JOURNAL   J Clin Invest 98 (10), 2277-2283 (1996)
   PUBMED   8941644
REFERENCE   5  (bases 1 to 634)
  AUTHORS   Hendrickson,B.A., Zhang,W., Craig,R.J., Jin,Y.J., Bierer,B.E.,
            Burakoff,S. and DiLella,A.G.
  TITLE     Structural organization of the genes encoding human and murine
            FK506-binding protein (FKBP) 13 and comparison to FKBP1
  JOURNAL   Gene 134 (2), 271-275 (1993)
   PUBMED   7505249
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120557.12, DV655383.1 and CF949699.1.
            
            On Jan 31, 2018 this sequence version replaced NM_001166368.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI555826.1, DV655383.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC120557.12        18514-18516
            4-628               DV655383.1         1-625
            629-632             CF949699.1         445-448
            633-634             AC120557.12        21240-21241
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.12 cM"
     gene            1..634
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /note="FK506 binding protein 2"
                     /db_xref="GeneID:14227"
                     /db_xref="MGI:MGI:95542"
     exon            1..71
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     exon            72..240
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..498
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /EC_number="5.2.1.8"
                     /note="peptidyl-prolyl cis-trans isomerase FKBP2;
                     rotamase; 13 kDa FKBP; PPIase FKBP2; immunophilin FKBP13;
                     13 kDa FK506-binding protein"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase FKBP2
                     precursor"
                     /protein_id="NP_001159840.1"
                     /db_xref="CCDS:CCDS29515.1"
                     /db_xref="GeneID:14227"
                     /db_xref="MGI:MGI:95542"
                     /translation="MRLSWILTILSICLSALAAATGAEGKRKLQIGVKKRVDHCPIKS
                     RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKL
                     VIPSELGYGERGAPPKIPGGATLVFEVELLKIERRSEL"
     exon            241..353
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     exon            354..400
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     exon            401..436
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     exon            437..634
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      607..612
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /note="hexamer: AACAAA"
     polyA_site      632
                     /gene="Fkbp2"
                     /gene_synonym="mFKBP13; mFKBP2"
                     /note="major polyA site"
ORIGIN      
        1 gtagcgacga agacgcgcct gcgcagaagt gacagcacga gcgggattgg ctccgggggc
       61 gcggcgagga gagacatgag gctgagctgg atcctgacaa tactgtccat ttgcctgagt
      121 gccctggcag cagccacggg ggccgaaggc aaacggaagc tgcagattgg agtgaagaaa
      181 cgtgtggacc actgtcctat caagtctaga aagggagatg tcttacacat gcactacacg
      241 ggaaagctag aagatgggac ggagtttgac agcagcctac cacagaacca gccctttgtt
      301 ttctcccttg gcactggcca ggttatcaag ggctgggacc aggggctgct ggggatgtgt
      361 gaaggggaaa agcggaagtt ggtgatccca tccgagctgg ggtatggaga gcggggagcc
      421 cccccaaaga tcccaggtgg agcaaccctg gtgtttgagg tggagctgct caagattgag
      481 agacgctcag aactgtagca ggctgcagag ggctaggagg cccccccgtc agggaccaga
      541 actgtagcag gctgcagagg gctaggaggc ccccatcagg gaccagactg tttaaaaaca
      601 aaaacaaaca aaaaaacctt taaaaccccc aaga
//
