LOCUS       NM_001267846            9817 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus fidgetin (Fign), transcript variant 2, mRNA.
ACCESSION   NM_001267846
VERSION     NM_001267846.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9817)
  AUTHORS   Ogujiofor,O.W., Pop,I.V., Espinosa,F., Durodoye,R.O.,
            Viacheslavov,M.L., Jarvis,R., Landy,M.A., Gurumurthy,C.B. and
            Lai,H.C.
  TITLE     An Atoh1 CRE Knock-In Mouse Labels Motor Neurons Involved in Fine
            Motor Control
  JOURNAL   eNeuro 8 (1) (2021)
   PUBMED   33468540
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9817)
  AUTHORS   Tenney,A.P., Livet,J., Belton,T., Prochazkova,M., Pearson,E.M.,
            Whitman,M.C., Kulkarni,A.B., Engle,E.C. and Henderson,C.E.
  TITLE     Etv1 Controls the Establishment of Non-overlapping Motor
            Innervation of Neighboring Facial Muscles during Development
  JOURNAL   Cell Rep 29 (2), 437-452 (2019)
   PUBMED   31597102
REFERENCE   3  (bases 1 to 9817)
  AUTHORS   Matamoros,A.J., Tom,V.J., Wu,D., Rao,Y., Sharp,D.J. and Baas,P.W.
  TITLE     Knockdown of Fidgetin Improves Regeneration of Injured Axons by a
            Microtubule-Based Mechanism
  JOURNAL   J Neurosci 39 (11), 2011-2024 (2019)
   PUBMED   30647150
  REMARK    GeneRIF: Knockdown of fidgetin improves regeneration of injured
            axons by a microtubule-based mechanism.
REFERENCE   4  (bases 1 to 9817)
  AUTHORS   Suzuki,A., Abdallah,N., Gajera,M., Jun,G., Jia,P., Zhao,Z. and
            Iwata,J.
  TITLE     Genes and microRNAs associated with mouse cleft palate: A
            systematic review and bioinformatics analysis
  JOURNAL   Mech Dev 150, 21-27 (2018)
   PUBMED   29475039
REFERENCE   5  (bases 1 to 9817)
  AUTHORS   Wang,D., Wang,F., Shi,K.H., Tao,H., Li,Y., Zhao,R., Lu,H., Duan,W.,
            Qiao,B., Zhao,S.M., Wang,H. and Zhao,J.Y.
  TITLE     Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is
            Associated With Reduced Congenital Heart Disease Susceptibility
  JOURNAL   Circulation 135 (18), 1733-1748 (2017)
   PUBMED   28302752
REFERENCE   6  (bases 1 to 9817)
  AUTHORS   Stubbs,L., Huxley,C., Hogan,B., Evans,T., Fried,M., Duboule,D. and
            Lehrach,H.
  TITLE     The HOX-5 and surfeit gene clusters are linked in the proximal
            portion of mouse chromosome 2
  JOURNAL   Genomics 6 (4), 645-650 (1990)
   PUBMED   1971250
REFERENCE   7  (bases 1 to 9817)
  AUTHORS   Iakovlev,M.I., Platonov,E.S. and Koniukhov,B.V.
  TITLE     [Influence of mutant genes on crystallin synthesis in the forming
            mouse lens. II. Fidget and ocular retardation genes]
  JOURNAL   Ontogenez 8 (2), 115-120 (1977)
   PUBMED   904847
REFERENCE   8  (bases 1 to 9817)
  AUTHORS   Konyukhov,B.V. and Sazhina,M.V.
  TITLE     The cell cycle and retinal histogenesis fidget mutant mice
  JOURNAL   Dev Biol 54 (1), 13-22 (1976)
   PUBMED   1001817
REFERENCE   9  (bases 1 to 9817)
  AUTHORS   Wallace,M.E.
  TITLE     Hydronephrosis in the mouse: the effects of the short-ear gene, sex
            and ureteral vascular system
  JOURNAL   Am J Anat 147 (1), 1932 (1976)
   PUBMED   970345
REFERENCE   10 (bases 1 to 9817)
  AUTHORS   Johnson,D.R.
  TITLE     The interfrontal bone and mutant genes in the mouse
  JOURNAL   J Anat 121 (Pt 3), 507-513 (1976)
   PUBMED   1018005
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC059266.1 and AL928553.8.
            
            Transcript Variant: This variant (2) has an additional exon in the
            5' coding region, which results in a downstream in-frame start
            codon, compared to variant 1. The resulting isoform (2) has a
            shorter N-terminus, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059266.1, BU706640.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-998               BC059266.1         1-998
            999-9817            AL928553.8         43784-52602         c
FEATURES             Location/Qualifiers
     source          1..9817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 37.19 cM"
     gene            1..9817
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /note="fidgetin"
                     /db_xref="GeneID:60344"
                     /db_xref="MGI:MGI:1890647"
     exon            1..197
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /inference="alignment:Splign:2.1.0"
     exon            198..367
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /inference="alignment:Splign:2.1.0"
     exon            368..425
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /inference="alignment:Splign:2.1.0"
     exon            426..9817
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /inference="alignment:Splign:2.1.0"
     CDS             434..2680
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="fidgetin isoform 2"
                     /protein_id="NP_001254775.1"
                     /db_xref="GeneID:60344"
                     /db_xref="MGI:MGI:1890647"
                     /translation="MQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWA
                     NDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSL
                     NSEAVYPMNCVPDVITASKAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSH
                     TVPSLHAGLPSQEYAPGYNGSYLHSTYSSQATPALPSPHPSPLHSSGLLQPPPPPPPP
                     PALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPP
                     TTVPGYTYQGHGLTPIAPSALTNNSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQ
                     SPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFSSQSSRALTPPS
                     YSTAKNSLGSRSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAATSSNHSVDEQL
                     KNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP
                     RSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCR
                     QPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEE
                     IDESLRRYFMKRLLIPLPDSTARHQIIVQLLTQHNYCLNDKEFALLVQRTEGFSGLDV
                     AHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEW
                     NKMFGCSQ"
     regulatory      4696..4701
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /note="hexamer: AATAAA"
     polyA_site      4717
                     /gene="Fign"
                     /gene_synonym="Fgn; fi; fidget"
                     /note="major polyA site"
ORIGIN      
        1 ggcatgctgg ctccttccaa gcagctgttt tgggtttgaa attccaacat ggcagaggct
       61 gcagtccgtc ttcccttcaa aaacttggaa tgatttcaaa tcataggcac cttcacttaa
      121 ccctagcttc cattcatcag caaacacatc ggatcgatgc tacgctaacc tatcgggagc
      181 tcgctctgcg cgtccaggtt aaatgaatac ctgacgaaag ggcccacgtt tcaaggcagt
      241 gacatttgat agctgagagg aaaagtggct ttaatgaaaa gcaacctttg gaattcctgc
      301 ttgtgagaaa tccaattcag ctttttgtgc taccagcaag aaatgatcag tagcaccagt
      361 gtttatggtc ccaggtcttt atgtatggac acaaagaatg atagaattct aggtcttggg
      421 aggaggcttg aagatgcagt ggacgccgga gcatgcccag tggccagaac agcactttga
      481 catcacctcg accactcggt ctcccgccca caaagttgaa gcctatagag gtcatttaca
      541 gcgcacctac cagtatgcct gggcgaatga tgacatatct gctctgactg cgtccaacct
      601 tctgaaaaaa tatgcagaga agtattctgg cattttggaa ggtcccgtag accgacctgt
      661 actcagcaat tattcagaca caccatcagg actcgtgaat ggtcggaaaa atgatagcga
      721 accctggcag ccttccttga attcagaagc cgtttatcct atgaactgtg tcccggatgt
      781 catcactgcc agcaaagctg gtgtcagctc agccctccct ccagtagacg tctcggcaag
      841 tatagggagc tcccctgggg tggccagcaa cctgacagag ccaagttact caagtagtac
      901 ctgtggaagc cacacagtac ctagtcttca tgcggggctc ccatctcagg aatatgctcc
      961 gggatacaac ggctcatatt tgcattctac ctacagcagc caggccacac ctgcacttcc
     1021 ttcgcctcat ccgtccccgt tgcatagttc tgggcttttg cagccaccac cccctcctcc
     1081 tcccccacca gccctggtcc caggctacaa cgggacttcc aatctctcca gttacagtta
     1141 tccctctgct agctatcctc ctcagactgc cgtggggtct gggtacagcc ctggcggagc
     1201 accccctcct ccttcagcat acctgccttc aggaattcct gctcccaccc ctctgccccc
     1261 cactaccgtt cctggctaca cctaccaagg tcatggtttg acacccattg caccctctgc
     1321 tctgaccaac aattcagcaa gttctctcaa aaggaaagct ttctatatgg cagggcaagg
     1381 agacatggac tccagttacg gaaattacag ctatggccaa cagagatcga cacagagtcc
     1441 tatgtaccga atgcccgaca acagcatttc aaactcgaat cgggggaatg gctttgacag
     1501 aaatgctgaa acatcatcct tagcatttaa gccaacaaag cagctgatgc cctctgagca
     1561 gcaaaggaaa ttcagcagcc agtccagtag ggctctgacc cctccttcct atagtactgc
     1621 taaaaattca ttgggatcaa ggtccagtga atcctttggg aagtatacgt cgccagtcat
     1681 gagtgagcac ggagacgacc atcggcagct cctcgctcat ccaatacaag gtcccggact
     1741 ccgtgcagct acctcatcca accactctgt ggacgagcaa ctgaagaata ctgacacaca
     1801 cctcattgac ctggtcacca atgagatcat cacccaagga cctcctgtgg actggagcga
     1861 catagctggt cttgacctgg tgaaggcggt tattaaggag gaggttttgt ggccagtgct
     1921 gaggtcagat gcattcagtg ggctgaccgc cttacctaga agcatccttc tcttcggacc
     1981 tcggggtaca ggcaaaacac ttttgggcag atgcatagct agtcagctag gggccacgtt
     2041 tttcaaaatt gccggttccg gactcgttgc aaagtggata ggagaagcgg agaaaatcat
     2101 ccacgcctct tttcttgtgg ccaggtgtcg ccagccctcg gtgatttttg ttagtgacat
     2161 tgacatgctt ctctcctctc aagtgagcga ggaacacagt ccagtcagtc ggatgagaac
     2221 cgaatttctg atgcagctgg acactgtact gacttcggct gaggaccaaa tcgtagtcat
     2281 ttgtgccacc agtaaaccag aagaaataga tgaatctctt cggaggtact tcatgaaaag
     2341 acttttaatc ccacttcctg acagcacagc gaggcaccag ataatagtac agctgctcac
     2401 acagcacaat tactgtctca atgacaagga gtttgcactg cttgtccagc gcacagaagg
     2461 cttttctgga ctagacgtgg ctcatttgtg tcaggaagca gcagtgggac ctctccatgc
     2521 tatgccagct acagaccttt cagccattat gcccagccag ttaaggcccg ttacatatca
     2581 agactttgaa aatgctttct gcaagattca gcctagcata tctcaaaaag agcttgatat
     2641 gtatgttgaa tggaacaaaa tgtttggttg cagtcagtga taacatcttt aaaaaaagaa
     2701 aaaaaaatgt aatgaatgtt ggcacacaca taaaacctgc tacataggga atagagcccc
     2761 tttccagtag tgtttcaatt gctaagggta ctggggaaga cgacgattat gttgcatctt
     2821 tagagtcagg gtagctttgg aagaagcagg catccgatga gagcctctga tttggaagcc
     2881 ccagctgaca gaaagcatat acatgtggat gctcggatcg gttcaagcta gacgacactc
     2941 accgagaagc aaggtgcaag tgtgttgatt tcagaaggac atgaacctcg tgtgttgatt
     3001 ccattctgct gttctcgaga tttagttgct gtcaagtgcc tggagtggtg ctttattttg
     3061 tttgtttgtt tgtttgcctc acaattacat tggtggcatg tgctaatata aagagcttta
     3121 acttcaaaca ctattggact aaagagatga acggttgtgt tacaacagaa aaccagattt
     3181 ttttggccat tttaagagca accgtattcc tcaaccctgt ctgttctgaa gtgttagcta
     3241 agagcaggta aaacagggta acggtgatct ggaccttaat ttctgcagtt catttctttt
     3301 aatgttcttg tctgcaaaaa ctcaggaaag tgattgtgat ttgtacagta cctcaaagga
     3361 atgtgttaaa agcactatgt actgctgaga gtaatagggt aggcttcaat gttactttat
     3421 attaaaatgt atgtttacct caacaattgg agaatagcaa ggaaaattat tttgaatgta
     3481 tccagaaaag aaaagaaaaa tactgaagtg tgatacaact gaatatttac agtttaaaag
     3541 tagaagtgga aggatttttt ttttaaagtt ctcttactaa ttatggggaa ttattaacca
     3601 gagcagaaca attactgaag agttcttaat gcattgctct ccatgatgat taagtggaaa
     3661 tgttcataga agttacactg gttaattgaa aagctgtgtc ttcagtttgt gttggtgttt
     3721 agagcagtca gctgcagacc tgtttaagac cctgaaagtg acagaaccta caaactgtat
     3781 ctgccttcta ctgccatggt ggaggtggag gtggaggtgg aggtggaggt ggtggtggtg
     3841 gaggatgttt tggaagctct ctcctaaacc tctaggggaa gagtctattc cactcagagt
     3901 tgctaggctt acagagctat ttcacaaaaa gcagaggata gaaccaaatc aaacatgcaa
     3961 acttaaaaaa aaaaaaaaaa aaaaaaaagc aaccaatcac aggtatctgc agagcacccc
     4021 ccacacgtgc ccctccccca tgccgcatct tgacttcgat cttcagagtg cactttcgct
     4081 tctcatcctc aagcccaccc ccaccccagg ctgtagaact cctacgttca tttctacctc
     4141 agtttcgtta tgtttctttt ggaaagtcaa gtgagaaatt agacgtggac atgtatacca
     4201 caacagagct tgccaaatgt ggggactttt gcgtcctgtt gtgttttctt ccctcctttg
     4261 tctgcttccc ctgtaacacc agtctttatg cattctttca cctctgaaga ctaccacaca
     4321 gcaatgtggc agtcctttct caccctgccc ctctgctcct gcttccacca ggttgttctt
     4381 tgtcttctgt aatgcagtat gtgcaagttt tcattgacag ctggctgaag ttcaccaatg
     4441 tctctctttc actgtcacag tgcaggacag agctttccac agccactgcc tgtgcagaat
     4501 cagagcagcc tagcattttg aatgtatttt cctgtatttt cctgtttttc cctccttttc
     4561 ttttctttac ttttcttttt ctttttttct ttcttttttt ttttattttg tttaaattta
     4621 gagatgcagt aattgttgcg aagcactggc attttgtgta ttcaataagt gatgtacatt
     4681 tttaaggtaa ttttaaataa atgcaatggc agccccatga aaggtctttc tgttattttt
     4741 ttttccttct tttttttttt cctgagctca tctacaagtt aattctctga aacacttaac
     4801 acagagaaac tgaataagaa aatgaactcg tggtatttca aacattttat gatatttgat
     4861 tagtaatctt tctctctttt ttttttcccg ttgctaaaac tgagcaaatg aactagaatt
     4921 taatggactg tgaacatcta tcaacttaca ctgttctaaa atagatccca tattttaaaa
     4981 gcagtgcctt tcactaagga gacacaaatg ataatactac ttagatatgt cctctgtttt
     5041 tcacaagtga ataaatgctt tagtcatatt ccggatctac cctatgcact gcccatgata
     5101 aggagattct aatattcact aacttgtgag cccatattga tctcattcac aagtttattc
     5161 tctgtgcagt actgacccat cttctctatt agagctcaca cctcatttcc accaatatgc
     5221 tgtgctcact aataaagtga aaagtaaaaa catctggcac gttttgacaa acccaatcct
     5281 ctttagtcaa ccttcgagaa cccagaatta acccacattg tttggtgtgt ggttttcggg
     5341 acttaatgcc aaatatatga gatgacagtt gtgctttgtt ctcacagtac tgataataaa
     5401 ctgaagtcat acatgttggc tgatagcttt aaatggcttt aaattagttt gagatatgaa
     5461 tgacttaaag attagtttga gatatgaatg gtctgagatc catggattga gcagaagctt
     5521 gaaattacat gtaatttcca cttagcccac ccaggtctag aattatctga tagcaaagca
     5581 ggcaagttga agaaacgaaa cactcacgct ctagcaaggt ttttaactcc atgtgtcagc
     5641 agtgtgaaaa ctccaatgga ctatcataat caggacgtct tttctgccca tccatttgag
     5701 agcttggggg agaacaagtt ccagatctcc agaagtgagc atggatattc agccctagaa
     5761 caaaactagg taattgttgg cctctctttg attgcttggg atttggagga ggctcctaat
     5821 gagtgtaagg tagtgaacca gtcagtcctt tccagttgca ggaggagatc cagccagcct
     5881 cgtttatagc cctcaattcc ttcctcacaa ctgtaataac atttccaaca gggatgaaaa
     5941 ggaggagggg ggaaatactt caggcaaagg atcaatagac attcaagagg cagctcatcg
     6001 tgggtttcta tgggacacta gtgaaaatac tctatgctgc tgacttgttt ctctccaaaa
     6061 tatttagagc attagtgaca atgtggagaa ctttgctgac tgagctggtc aatggaatgt
     6121 gaaggcagta tactttaagg ctatttactc tcacacagaa tgtttatcta ttagtcaatt
     6181 tgtattctac tcaaatgcag atagacgggt ataatgtttt cttgtgcatt tgaaacctat
     6241 caaggagaaa ataaaccatt ccactaaaat acataggcca aacaccatct ggacaagtga
     6301 taaacactat ccagaggcta tactaaatgc aaggtcaatt tacatgggct gcagagcact
     6361 tggctatgca gttttgaaat gtagacttcc aaaaaaaaat tccaaattaa ttcttgcaat
     6421 aggtcattgt aaatttaaat atatttctga gttggaaagg atgttttaga ggcatttaga
     6481 atttctttct ctgaaaatat atacaacctc aagcaggaag gtatttctgt atgcccactc
     6541 tcatgtttct tagcaagaat tgggaatcct gattattaag tccgtattac agagtgaaag
     6601 gcacgtagtt tattgaacta ttgaggccac taaagttctg atatatataa atataaatat
     6661 aagtataatg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tatgagtgtg
     6721 ctgtgtcaac caccacctat ttgaacttta aaatgaaccc attgttttac attatctgga
     6781 ggtaactgct tgcttgcttt tttcctatgt gccaaaatac acatgactcc ttcaaaattc
     6841 tgttcaaata tgactttttt ttttagtaaa accttcagtt ttgaatcatt tgccgatgta
     6901 atgaaacaca ctagcaaaga caaagcgatt agtatttcag atttcaccac cagctatact
     6961 tgtgactaac caacccatga actaaaagct cacagtctgc taagaccttt ggttgacatt
     7021 cgattttgaa cctgccagat gcgtttgtgt gaaccaggga tactgcatct ttaatgaaca
     7081 agtctctcct ctttcccctg tttttaaata caacacaagg ggtgtagcac taggcactgc
     7141 aattgtcaaa gacaattaga ctgaaagcag ggaaatctca cctccctgtc tcagtgatat
     7201 gtagaatgtg ggcagcctgg gtcagccttg ccacagagtg gtgtgagaag atatgaatca
     7261 gtcctataga atgttaaata tttataaaat gggtttgtag tgcgccaagg ttgggagcac
     7321 attcatttct tctttttgtc ttatgaaaca aaaggaaaaa aagcaaaagt ttatttctag
     7381 gcttcttctc tccctaggcc taggtatatt ctctctctct ctctctctct ctctctctct
     7441 ctctctctct ctctctctct ctctctctct cccttcttcc ctccctccct ccctctctcc
     7501 ctccctccct gtctccatcc ctccctccat ttctctcttt ttttcttccc tctcttcctc
     7561 ccttcctttc ctcccctgta tggatctgtg tgtatgagtg attttttttc cttgtggatt
     7621 aaatacagtt gctagagaat attcattttt ttatttgttt tccttttttt ttcatctgac
     7681 tattcagaca ttgttcctta taaccatttc tacctcattg ctacatattg tacatgtagt
     7741 atttatttgt tgtctttttt tgaatgtcat gcatttcgta agaaaaagac tagtccttga
     7801 acttgaacag tctacctcag aaagactgtc tttacactga acagtattag caagctaaat
     7861 ggtaagacgc attagcaaag tgtggcaggg tggataatgc gtgaggactt gggatcctga
     7921 tggactttta attgtaccca caactcaaga ctgcttaaag ggacttgaaa gaaattgtgc
     7981 actgtgtagg tcttcatcaa ggtcccattt agaacctaag aaatacagct ttgtcactgc
     8041 tcgcccatct ctgagaaaca tgttagcatt cccaagtatt ttacactggc aatcagacta
     8101 cttaagacaa acaaatagaa acatgtgtta cattcttttg actgacaccc tcacttccta
     8161 agtttaagag aaacatagta cttaatgatt gctgactgca gtctttggtg gttttaaatg
     8221 ccttcctttt agttctgtga ctcctgatat cagtgaatgg aaacaccacc attgcacagg
     8281 cctgcacaac accaaaataa aataaaccaa aaccaaaacc aaaacaaaac aaaaaaacaa
     8341 aattaaaaat ggcacttccc aaaggaatta acacacatgg agtcatggtg cttcgaagtt
     8401 ccctatatga aaacattttt tttttgtttc ctatttccct ttgtaacatg tatttgttcc
     8461 ttaaagtact gtacaaccaa tggcacattg aattactttg tatggtgtgt tttataattg
     8521 actatttatt ttagcattga ttcttttcct tcaccagctc tatattacag tagcaaaaga
     8581 actcttactt acttaaaaac atgctgaaag gggtccaccc ccccccaccc cccgcccaat
     8641 cgatgaaagg acttttgaag ttgcctctca gcaaagtgtg gatattttac aaaagcaaat
     8701 gaactgtgac aatccacaac tcccacagat gtgaattcag aactgcatct gaaaactccc
     8761 ggtatgcctg acaatctatg ctttaagttt cattaacaaa ttggagtggc atccaatcct
     8821 ttcacaaaca attccgagca ggaatttctt gtctagaggc tgtcttgtag tgattaagag
     8881 agggtttgat tttgtttgtt tactgtatta ggtgaggaat gccatatttc ttgtcagcta
     8941 acagtacttg tctgagacag aattcaaggg gaatttaaaa aaaaaaaagg agaaaaagaa
     9001 acctaactaa ttaaaatttc tgtgcacttt gcttctctga ccatattgat tttatttgct
     9061 taaattgaaa caatacgctg gatttgacca gattttgacc ctttgtgaga agaaaagccc
     9121 tatatagtcc atgtttctct gggttattct agtgctgttt gcttacttct tctgcaaatt
     9181 ctgaatcatt ttttgtgtgt gtgcattatt ttacatctgc tgaagctaaa tgtgttatta
     9241 ttgcactcat taaaaatgaa acaatccatt tctcttggaa aaaaatgaca agctttagat
     9301 gatgaaagct taaattatcc atcacttgca aaatgaattc atataatttg tgaacattat
     9361 taatgtaaat gagacatttc tgcttagatt tttttttatt ttgatgggat cattatatgg
     9421 ttgatcatat gtgtgtagga agctgctgta caattaactt ggagatctga aaatgctttt
     9481 tgtcctcatt gttacagttt caattgtaat ccattgcatc tcattttctt gggtgttggc
     9541 actgtaatat attaaaaaaa aaaatcagtg ctcagtattg taactaactg tccctactga
     9601 atattccttt tcataaatac ttgctaccac agggaaatta agttttcata tagaataact
     9661 agtttcagta gtaagcattg aaaaattaaa aatgtggttc aaggcagata tttttatgaa
     9721 aagttttctc tattgtaaaa tttgttgtat atggctatgc tactatcatg gaataagaaa
     9781 agacaagcgt acctcaaata aaaaaaaatt ctgagtt
//
