LOCUS       NM_178887               4764 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus fibrinogen C domain containing 1 (Fibcd1), mRNA.
ACCESSION   NM_178887
VERSION     NM_178887.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4764)
  AUTHORS   Choi,J.S., Ayupe,A.C., Beckedorff,F., Catanuto,P., McCartan,R.,
            Levay,K. and Park,K.K.
  TITLE     Single-nucleus RNA sequencing of developing superior colliculus
            identifies neuronal diversity and candidate mediators of circuit
            assembly
  JOURNAL   Cell Rep 42 (9), 113037 (2023)
   PUBMED   37624694
REFERENCE   2  (bases 1 to 4764)
  AUTHORS   Bhattacharya,S., Maupin,A.J., Schlosser,A.G., Fuchtbauer,E.M.,
            Gloria,Y.C., Weber,A.N.R., Holmskov,U., Moeller,J.B. and
            Templeton,S.P.
  TITLE     The role of FIBCD1 in response to Aspergillus fumigatus in lung
            epithelial cells
  JOURNAL   PLoS One 18 (3), e0282347 (2023)
   PUBMED   36888604
  REMARK    GeneRIF: The role of FIBCD1 in response to Aspergillus fumigatus in
            lung epithelial cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4764)
  AUTHORS   Fell,C.W., Hagelkruys,A., Cicvaric,A., Horrer,M., Liu,L.,
            Li,J.S.S., Stadlmann,J., Polyansky,A.A., Mereiter,S., Tejada,M.A.,
            Kokotovic,T., Achuta,V.S., Scaramuzza,A., Twyman,K.A., Morrow,M.M.,
            Juusola,J., Yan,H., Wang,J., Burmeister,M., Choudhury,B.,
            Andersen,T.L., Wirnsberger,G., Holmskov,U., Perrimon,N.,
            Zagrovic,B., Monje,F.J., Moeller,J.B., Penninger,J.M. and Nagy,V.
  TITLE     FIBCD1 is an endocytic GAG receptor associated with a novel
            neurodevelopmental disorder
  JOURNAL   EMBO Mol Med 14 (9), e15829 (2022)
   PUBMED   35916241
  REMARK    GeneRIF: FIBCD1 is an endocytic GAG receptor associated with a
            novel neurodevelopmental disorder.
REFERENCE   4  (bases 1 to 4764)
  AUTHORS   Bhattacharya,S., Amarsaikhan,N., Maupin,A.J., Schlosser,A.,
            Fuchtbauer,E.M., Holmskov,U., Moeller,J.B. and Templeton,S.P.
  TITLE     FIBCD1 Deficiency Decreases Disease Severity in a Murine Model of
            Invasive Pulmonary Aspergillosis
  JOURNAL   Immunohorizons 5 (12), 983-993 (2021)
   PUBMED   34937773
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4764)
  AUTHORS   Moeller,J.B., Leonardi,I., Schlosser,A., Flamar,A.L., Bessman,N.J.,
            Putzel,G.G., Thomsen,T., Hammond,M., Jepsen,C.S., Skjodt,K.,
            Fuchtbauer,E.M., Farber,D.L., Sorensen,G.L., Iliev,I.D.,
            Holmskov,U. and Artis,D.
  TITLE     Modulation of the fungal mycobiome is regulated by the
            chitin-binding receptor FIBCD1
  JOURNAL   J Exp Med 216 (12), 2689-2700 (2019)
   PUBMED   31601676
  REMARK    GeneRIF: these results identify FIBCD1 as a previously unrecognized
            microbial pattern recognition receptor through which intestinal
            epithelial cells can recognize and control fungal colonization,
            limit fungal dysbiosis, and dampen intestinal inflammation.
REFERENCE   6  (bases 1 to 4764)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   7  (bases 1 to 4764)
  AUTHORS   Lee,K., Tan,J., Morris,M.B., Rizzoti,K., Hughes,J., Cheah,P.S.,
            Felquer,F., Liu,X., Piltz,S., Lovell-Badge,R. and Thomas,P.Q.
  TITLE     Congenital hydrocephalus and abnormal subcommissural organ
            development in Sox3 transgenic mice
  JOURNAL   PLoS One 7 (1), e29041 (2012)
   PUBMED   22291885
REFERENCE   8  (bases 1 to 4764)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC060634.1, AK084379.1, AK046338.1 and AI448887.1.
            
            On Dec 28, 2007 this sequence version replaced NM_178887.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060634.1, AK046338.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               BC060634.1         1-369
            370-597             AK084379.1         335-562
            598-3503            BC060634.1         598-3503
            3504-3576           AK046338.1         3466-3538
            3577-4747           AK046338.1         3540-4710
            4748-4764           AI448887.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..4764
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 21.89 cM"
     gene            1..4764
                     /gene="Fibcd1"
                     /note="fibrinogen C domain containing 1"
                     /db_xref="GeneID:98970"
                     /db_xref="MGI:MGI:2138953"
     exon            1..295
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             224..1603
                     /gene="Fibcd1"
                     /codon_start=1
                     /product="fibrinogen C domain-containing protein 1"
                     /protein_id="NP_849218.2"
                     /db_xref="CCDS:CCDS50564.1"
                     /db_xref="GeneID:98970"
                     /db_xref="MGI:MGI:2138953"
                     /translation="MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLA
                     VAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLT
                     DSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLR
                     KGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKA
                     DLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTD
                     GGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLE
                     DFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDS
                     DHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEM
                     KIRPVREDR"
     exon            296..769
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            770..929
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1066
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1163
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1343
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..4751
                     /gene="Fibcd1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1703
                     /gene="Fibcd1"
     regulatory      4724..4729
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fibcd1"
                     /note="hexamer: AATAAA"
     polyA_site      4746
                     /gene="Fibcd1"
                     /note="major polyA site"
ORIGIN      
        1 gcgggacgcg gggacggcgc ggcgcgggcg gctctcggag gctcgcgccc gcgctcccag
       61 caatcacacg cgctcacacg cagcctagct ggcggccgcc gctcccgggc caccccggat
      121 ccccggcacc gaggggacct cctgcgagtg caacgcaccc tgtgcacccc tcgcctcctt
      181 tgcactcgcc cttgccccgc aaccccgctg gtcttgctgg aagatggtcc acgagcggtg
      241 gaagaccgtg ggcagcgcgt cccaacttga ggaccgaccg cgcgacaaac cgcagcgagc
      301 aagctgcagt tatgtcctgt gcacggtgct cctgtccctt gcggtgctgc tggcggtggc
      361 tgtcaccggt gtggttctct tcctgaacca cacccacaca ccaggcacgg cgcccccacc
      421 catcgtcagc acggggactg ccggagccaa cagtgccctg gtcactgtgg agagggctga
      481 cagctcccac ctcagccttc tcatcgaccc tcgctgcccc gacctcactg acagcttcgc
      541 ccgcctggaa ggcatccagg cctccatcct tcgggcactg agtgagcacc aggcacagcc
      601 gaggctggac ggtgcccccg agctgctgga cgcactggct gaccagctgc cccggctgct
      661 aacccgggcc tctgagctgc aggctgaatg tgctgggctg cgcaagggac acagcctgct
      721 gggccagggc ctcagcaccc tgcagagtga acagggtcgc ctcatccagc ttctctctga
      781 gagtcaaggt cacatggctc acctggtgaa ctcagtcagt gatgtcctgg aggctctgca
      841 gagggagcgg ggcctaggcc ggccccgtgt caaggctgac cttcagaggg ccccttcccg
      901 gggagcccgg ccccgaggct gtgctaatgg ctctcggccg cgggactgcc tggatgttct
      961 cctgagtgga cagcaggatg atggtgtcta ctctatcttc cccactcact acccagctgg
     1021 cttccaggtc tactgtgaca tgcgcactga tggtggaggc tggacggtat ttcagcgccg
     1081 ggaagatggc tctgtgaact ttttccgagg ttgggaggcg taccgggagg gcttcggcaa
     1141 gctcacagga gagcactggc tggggctcaa gcggattcac gccctgacca cacaagcagc
     1201 atacgagctt cacgtggacc tagaagactt tgacaacggc accgcctatg cccactacgg
     1261 gagttttggt gtgggcttgt tctctgtgga ccccgaggag gatgggtacc cactcacggt
     1321 ggctgactac tccggcaccg caggtgactc cctcctgaag cacagtggca tgaggtttac
     1381 caccaaggac cgggacagcg accactcgga gaacaactgt gccgccttct accgaggagc
     1441 ctggtggtac cgcaactgtc acacatccaa cctcaatggc cagtacctgc gtggtgcaca
     1501 cgcctcctac gcagacggcg tcgagtggtc ctcttggacg ggatggcagt attcactcaa
     1561 gttctcggag atgaagatcc ggccggtccg tgaggaccgc tagactggcc cactgcccag
     1621 tgccagcgtc ctctggttat gtctagtccc tacacatctc atcccatgcc cactgctgca
     1681 agaacatgct ctgcccacct gtgcatggct ggtctgctct ttagtaggga tggcccaggg
     1741 tcagccctga aactcagctt cctgagccag tgacactcct tccccaacca ggtccctgtc
     1801 tatcaagtga catgctcttt ggttcctacc agcggagctg gcacctggca accccaaatc
     1861 ccacctgccc aggctttggt ccctgtgctt tgtctgctgc atcctggtaa ggcagcatct
     1921 cccattcttc ctggcttggc aaaaacatcc agaattgggg gcaggcagca ccttggtccc
     1981 ctccatcaga tcaaagtgga aggctcagac cttctcacct ctgacacctg tctgccctaa
     2041 ccccaatccc tcagggcctg gagaccctac ctcttatcag aggaccttgt gcagctgcca
     2101 cagctctctc tcatttgtgg ccaactgggc cgtggcacag ctgtctacaa agccccaagg
     2161 ccaagaccag acccctaggc cacccttccc tgggtctcca cagacctggg ggtttttatt
     2221 cttctggttg ctttcagagc tcatctgctc tttcccacct caaacaaggt ccacctgccc
     2281 tcctgcagag cacccatggg tcctgcccca catcatctgc ctgtggggca agggtgggac
     2341 tggcctaagc cagtgaggac ctcctggggt gaggctgtgc caggcttttg tgttctgccg
     2401 acctccatgg actgactcta ggatcttctc agaagccagc cagccctggg actcagcatg
     2461 gcccaagact accatctctg cagagagact gccccctgct ggctatcacg gacactgcca
     2521 tcagggtcta acaggtgggg tggggtggag gggagggcag gagacagagc cctcaaacag
     2581 gttggacatc tggacatttc cttgtccagc cttctcaaca cctgcacggg tgatcccgca
     2641 ggaaggcagg ctgcagcccc gccctcagct acctgcttgg cagctgagat gctcttctga
     2701 aagcctgaca ggggctttaa aagaactgga tggtaagatg gcaatggtga cctcctctgt
     2761 ctggaggcag aggcccatgc ctttcctttc tgccagactt gtaccaaagc ctgaagccac
     2821 cgatgaactg tgtgacctgc tcagtccctc acattgggcc tcgggtcttc agcaaggatc
     2881 tgtagcacct gtgagagtca aagccgtcct aggtgctgga caggactggt tatggtcccg
     2941 cgctggtggc acgaaacatg agtagagtag ccaaggttct gatgggacaa gggatacata
     3001 ggaaagtccc ctcccattcc ctctctgtcc ctgacacctg gcacctagct tcattgcaga
     3061 ggtgtgtggg agcttaaaca catcctggca gacactaccc acccccgagg ctggtgctaa
     3121 agtggcttct gttgccagct gccgctgtaa gcgctgctca gaagtgccaa gcgctttctg
     3181 atgtggtatc aaacaaactc cgtcgagtga agcaacagat tcacacatgc aagtgtggga
     3241 caggagggct gtgggccagg gctgggctgc agaatgcagg agctgaagct cagcccatca
     3301 gggcagctgg tgaagggtga catgcatccc tgtctggtca cattggaaat gacagccctt
     3361 cagcccagcc actgccccag ggacaccaag ctctctccca agccaggcta gtactctagg
     3421 gggtgtggtt ttgtcaaacg ctggccgagt gggcaggagt tagtagggag agaccaggtc
     3481 aacagtcctt caccttcctg gtgtgcaccc tccaagggca ggcgggagca ctgtccctgg
     3541 gagcactatt cctgcacact gggccacagc ctccagccct ggctttcatt cactggtctg
     3601 atgtctgtgt aggtggctgc cacctgtgat cagtgaccac gggaagcagg aatgctggga
     3661 agtttggggg gcaggacagg tccactaaga agacataatg tcagtgggct gtggtccctg
     3721 ataccccaga cctactttgg tttgtcaatg gaatgactaa ccagggtgag tctatgaagt
     3781 cacctggcag agccacactg cttatcttct tgggaagagt ctccacatct cacacgaggg
     3841 tcttggcact gtggctgtct ctactttgca aagcatcgaa aatctttcca agcctaggtt
     3901 ggctttgtgg attctaccaa aggcctcata gctgggtaca cctgggtcgt gccagtggcc
     3961 acctagacag catgcaggga gcagacagtg ccttgggtcc cctgcaaacc tgggctggtg
     4021 agtgaccagt tagagctgtg agcctctcct gtggcattag tggctcgtgc gtgtgggaca
     4081 ctagtgtttg taggtgggag tgtcatctcc agctcctggc tcttccctgc ccctcatctg
     4141 tgtcacccca agcctccagg tggagaacga gccatctgtg gccatggtca ctgcaggact
     4201 tggcccacaa ccagcacttc tagaagatag cagggccttg gataaccaga aagtctatga
     4261 gcaacagatg ccgtcctcaa gatgacttga ctctgaggtg ggagatatgt atgagctagg
     4321 cccacagctg ccctgagccc tgtgatctaa ggagcaacat gccagcagaa gtctcatgga
     4381 acccagaagt gtgatgaagc aacatggacc caaagtgccc gggggcctct caaagcctca
     4441 ttccttcatc tgcctttggc gcaggttgcc cgaggttctg gtggcccagc aactgcaggg
     4501 atccataaat ccagaggcca ggattcaggc tcagtggctg tgagtggggg tccgacctga
     4561 ggctagctgt gccaagcaga gcaggtgtgc atgctgtcag atacaatggg gccctggggc
     4621 tggaagcagc tctgagggtc agtgcagcac cccatgggca aacagtgggc ctagttgcta
     4681 cttggggctg tgtgcacccg gtgtcttgtg tacccttgtc ttcaataaag tctcgtggtg
     4741 acccagcacc aaaaaaaaaa aaaa
//
