LOCUS       NM_172682               4392 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus FHF complex subunit HOOK interacting protein 1A
            (Fhip1a), mRNA.
ACCESSION   NM_172682
VERSION     NM_172682.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4392)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4392)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4392)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   4  (bases 1 to 4392)
  AUTHORS   Boyle,M.P., Bernard,A., Thompson,C.L., Ng,L., Boe,A., Mortrud,M.,
            Hawrylycz,M.J., Jones,A.R., Hevner,R.F. and Lein,E.S.
  TITLE     Cell-type-specific consequences of Reelin deficiency in the mouse
            neocortex, hippocampus, and amygdala
  JOURNAL   J Comp Neurol 519 (11), 2061-2089 (2011)
   PUBMED   21491433
REFERENCE   5  (bases 1 to 4392)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV659303.1, DV651332.1, AK036881.1 and AI481830.1.
            
            On Oct 17, 2007 this sequence version replaced NM_172682.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-609               DV659303.1         1-609
            610-1014            DV651332.1         1-405
            1015-4385           AK036881.1         1-3371
            4386-4392           AI481830.1         1-7                 c
FEATURES             Location/Qualifiers
     source          1..4392
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 37.83 cM"
     gene            1..4392
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /note="FHF complex subunit HOOK interacting protein 1A"
                     /db_xref="GeneID:229488"
                     /db_xref="MGI:MGI:2444746"
     exon            1..121
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            122..345
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..3486
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /note="protein FAM160A1; family with sequence similarity
                     160, member A1"
                     /codon_start=1
                     /product="FHF complex subunit HOOK-interacting protein 1A"
                     /protein_id="NP_766270.2"
                     /db_xref="CCDS:CCDS17442.2"
                     /db_xref="GeneID:229488"
                     /db_xref="MGI:MGI:2444746"
                     /translation="MMSSVSTESKLQQAVSLKGVDPETCMIVFKNHWAQVVKILEKHD
                     PLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVCENIMEKLF
                     LWSLRREFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTATPAVEG
                     KLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGTVGQQARDA
                     LLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEDWHCILKDDW
                     LLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMT
                     TTAYLDLFLRSISEPALLEIFLRFILLHRHENVHILDTLTSRINTPFRLCVVSLALFR
                     TLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGI
                     TLTLGNQERDYILWSKCMHDGSGSEEQLLPETPCSPSSPSPPPPPAPAACIVEYGKAL
                     DISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPDPETFLQSLSEESRENSGHPEARL
                     PQQSVRTSGQTKDKSQSELEWDDSYDTGISSGADVGSPGPDDEVETPAPPAPIDPPKH
                     IQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDTEDTTEPQKDTSEPQGDTLEPL
                     EDTSEQQEDTSEQLEDTSELQEDTAEPQGDTADPTAEAQPKLQPEAQSLPTSNGPLSS
                     PDPETESQPSRESSDLCQNTFSEAKPENEPGVALALDSELIATTFEAEPQSELAVVST
                     ESEDFIAQYDQIIQELDSGTEGLTEQSIPISEPSLLTQQEERREECKEEEDDDFDSLM
                     AATPAVEAGSSPFGVGEDTAFSSRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNL
                     LLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPG
                     LLIQAQQYLLFRVDMSDMAPAALTKDPIQEISRPESDKTLLDGPPRVLQPFLGNRAKV
                     TRAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC"
     exon            346..972
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1131
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1218
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1386
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1466
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1657
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..2914
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            2915..3093
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3094..3232
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     exon            3233..4388
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4366..4371
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /note="hexamer: GATAAA"
     polyA_site      4388
                     /gene="Fhip1a"
                     /gene_synonym="9930021J17Rik; Fam160a1"
                     /note="major polyA site"
ORIGIN      
        1 gtcttgttgg ttggttgtgg tttgttaaga agttatgtgc aaagaagaag caagaagagc
       61 ttagatatcc tcacagcaaa gagcaaacct gcttcaagga actcaatgcc cttaatcagc
      121 agttttggaa aatgaccatg aagactgaag aaattacatt tttaacatga tacttggagt
      181 taatgactgc ttatggcatt ttcttgaaaa ttaaatatga cttaaaagcg tcaaaggttt
      241 atgatgtcat cggtttctac agaaagcaaa ctccagcagg ctgtgagcct gaagggagtt
      301 gacccagaaa catgcatgat tgtgtttaag aaccactggg cacaggttgt gaaaatctta
      361 gagaagcatg accccttgaa gaacacccag gcaaaatatg ggtccatccc cccagatgag
      421 gccagtgctg tgcagaacta tgtagaacac atgcttttcc tgctaatcga agagcaagcc
      481 aaggatgctg cgatggggcc aatcctggaa tttgtggtct gcgagaacat catggaaaag
      541 ctcttccttt ggagcttgag acgagaattc actgatgaaa ccaaacttga gcagctaaag
      601 atgtatgaga tgctggtcac tcagtcctac cagcctctgc tgcaccacaa gcccatcctg
      661 aagcccctca tgatgttgct gagctcctgt tcggggacag ccaccccagc tgtggaggga
      721 aagctagttg tcctgctcaa tcagctctgc tccatccttg ccaaagatcc atccatcctg
      781 gaactcttct tccacaccag tgaggaccaa ggggctgcca acttcctcat tttctctctt
      841 ctgataccct tcattcatcg agagggcaca gtaggccagc aagcaagaga tgctttgcta
      901 tttatcatgt ctctctctgc tgagaacagc atggtggcca atcacattgt ggaaaatacc
      961 tacttctgtc ccgtgcttgc aacgggactc agtggcctgt actcttcgct gcccacaaag
     1021 ctggaagaga agggtgagga ctggcactgc attctgaagg acgactggct cctgctgcct
     1081 gccctcgtgc agttcatgaa ctcgctggag ttctgtaacg cagtcatcca ggtggctcac
     1141 cccttgatcc gcactcagct cgtcagctac atttacaatg gatttttggt accagtattg
     1201 gctcctgcac tccataaggt gacggtggag gaggtcatga ccacaacagc atacctggac
     1261 ctcttcctgc gcagcatctc tgagccggcg ctcctggaga tcttcctccg cttcatcctc
     1321 ttgcaccggc atgagaacgt tcacatcctg gacaccctca ccagccggat caacacccct
     1381 tttcggcttt gtgtggtgtc cttggcgctg ttcagaactc tcatcggctt acactgtgaa
     1441 gatgtgatgt tacagctagt tttaaggtat ctggtcccct gcaatcacat gatgctgagt
     1501 caaaggtggg ctgtgaagga gagagactgt tactccgtgt ccgctgccaa gctgcttgcc
     1561 ttgacccctg tctgttgtgc cagtggcatc actttgacac ttgggaacca agaaagggat
     1621 tatattctct ggtccaagtg tatgcatgat ggctcaggat ctgaggagca gctgctgcca
     1681 gagacaccct gctcgccctc ttcaccttcc cctcctcccc cacccgcccc agcagcctgc
     1741 attgtggagt atgggaaggc cctggacatc agctacctgc agtatctgtg ggaggcccac
     1801 accaacatcc tccactgcat gagggactgc agagtgtggt cagccctcta tgatggggac
     1861 tcacctgacc ctgagacctt tctgcagagt ctgtcagagg agagccgaga aaactcaggt
     1921 cacccagagg ccagactccc acagcagagt gttaggactt caggacagac aaaggacaag
     1981 agccagtcag agctagaatg ggatgacagc tacgacactg gtatctcttc aggggcagat
     2041 gtgggctccc ccgggcctga tgacgaggtg gagaccccgg ccccaccagc acctattgat
     2101 ccccccaaac acatccaaga gatgaagaag aacgccatcc tcctcttcaa ggggtcctac
     2161 attgaggagt cagacttcca ggatgacgtg atggtataca ggctatgtgc tgagaaggac
     2221 acagaggaca ccacagagcc acagaaggac acttcagagc cgcaggggga caccttggag
     2281 ccactggagg acacttcgga gcagcaggag gacacctcag agcagttgga ggacacctca
     2341 gagctacagg aggacactgc ggagccgcag ggggacactg cagacccaac cgctgaggct
     2401 cagcccaagc tccagccgga agcccagagt ctccccacga gcaatggacc tctctctagt
     2461 cccgatcctg agacagagtc acaacccagc agggagagtt cagacctgtg tcagaacacg
     2521 ttctcagaag ccaagccaga gaatgagcct ggcgtagcct tagcattaga ctcggagttg
     2581 atagccacca cgtttgaggc ggaaccccag tcagaattgg cagttgtcag cacggagagt
     2641 gaagacttca ttgcacagta cgaccagatc attcaagaac tggactctgg cactgagggc
     2701 ttgacggagc agagcatccc tatctcagag ccctcacttc ttacacagca ggaagaaagg
     2761 agggaagagt gcaaagagga ggaggacgat gacttcgact ccctcatggc ggccacgcct
     2821 gccgtggagg ccgggtcatc cccatttggt gttggagagg atactgcctt tagcagccgc
     2881 catcccgtga ggactcagag tacgccgttc acaggcccat tcatcagcgt ggtcctgtca
     2941 aagctggaga acatgctgga gaactctctg catgtcaact tgcttctcat cggcatcatc
     3001 acccagctgg ccagctaccc acagccgctc cttcgctcct tcctcctcaa caccaacatg
     3061 gtcttccagc ccagcgtccg ctcgctctac caggtccttg catcggtgaa aaacaagatc
     3121 gagcagtttg cttctgtgga gagagacttc ccaggcctcc tcatccaagc tcagcagtac
     3181 ctgctcttca gggtggacat gtctgacatg gcccctgcgg cactcaccaa agatcccatt
     3241 caggagatct ccaggccaga aagtgacaag acccttttgg atggccctcc acgtgtgctt
     3301 cagcccttcc taggcaacag agccaaggtg accagggcac ccccaaacct gcctctgcca
     3361 gtgaagaaca ccatgctggc tgctgctctc ttcccagagt tcctgaagga gctggcagcc
     3421 ttggcccaag aacactccat tctgtgttac aagatcctgg gagactttga agactcttgc
     3481 tgttagcttt ttatactact attttcatag agatttggtt ttataaggtt atagtgtctt
     3541 gactgaatgt taaatgcaaa gctgcttatc aaaaatgtct actttgatat ttcctgacaa
     3601 tacttgattt atcggggggt tttggtacac ctcctctctc cagccgggtc tccccttgtt
     3661 acacagaatg tcttgtgagc cggctgtctc cttggcaggc tctttcagct gtgtttcctc
     3721 ttcagatggt ttgtagttgt ctcccatgcc ttggatggag gagacagaga ccctcagttt
     3781 gtagctcaga tgccatggag cgcacacgga ggttctgtga cctctggatg cctggtgggg
     3841 gtcagtgcct cagcagtctc acggaggttc ctccatggtg gcacacacat ggcctagcag
     3901 cctctgcaag aagtgaaatg taagaacgga gctcctcctg ccacatagga cacatcattg
     3961 gctgctctga attttacttc taggacttgc aatctttcca tacctattgc cttaatgttg
     4021 tggggaaaat ccccaagccc cagctgtctg cccaaaactt cgcacacaga gagaatctgg
     4081 aatgcaggat tttttttctt gttgcttgag agctgttcta atcattggag cacaaccaaa
     4141 actcaagaca gccttaattc agtaagattt gcacaaaagg aagcatacct atgcaaactt
     4201 tggatcttag gcatttgatc agatggaaaa aagtgtggtg tcatatactt atgttaaaaa
     4261 cattattgtt taagtatttt atgaaaacaa acgttaactt gtaacgcaaa gaggattttt
     4321 ttgggggggg gttgagggtg tgcagagctt ggaatgggtg caaaagataa aaattctgct
     4381 aactgtaaaa aa
//
