LOCUS       NM_028263               1775 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus fibroblast growth factor binding protein 3 (Fgfbp3),
            mRNA.
ACCESSION   NM_028263
VERSION     NM_028263.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1775)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1775)
  AUTHORS   Sampath Kumar,A., Tian,L., Bolondi,A., Hernandez,A.A., Stickels,R.,
            Kretzmer,H., Murray,E., Wittler,L., Walther,M., Barakat,G.,
            Haut,L., Elkabetz,Y., Macosko,E.Z., Guignard,L., Chen,F. and
            Meissner,A.
  TITLE     Spatiotemporal transcriptomic maps of whole mouse embryos at the
            onset of organogenesis
  JOURNAL   Nat Genet 55 (7), 1176-1185 (2023)
   PUBMED   37414952
REFERENCE   3  (bases 1 to 1775)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1775)
  AUTHORS   Tassi,E., Garman,K.A., Schmidt,M.O., Ma,X., Kabbara,K.W., Uren,A.,
            Tomita,Y., Goetz,R., Mohammadi,M., Wilcox,C.S., Riegel,A.T.,
            Carlstrom,M. and Wellstein,A.
  TITLE     Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts
            carbohydrate and lipid metabolism
  JOURNAL   Sci Rep 8 (1), 15973 (2018)
   PUBMED   30374109
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1775)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   6  (bases 1 to 1775)
  AUTHORS   Kang,P., Lee,H.K., Glasgow,S.M., Finley,M., Donti,T., Gaber,Z.B.,
            Graham,B.H., Foster,A.E., Novitch,B.G., Gronostajski,R.M. and
            Deneen,B.
  TITLE     Sox9 and NFIA coordinate a transcriptional regulatory cascade
            during the initiation of gliogenesis
  JOURNAL   Neuron 74 (1), 79-94 (2012)
   PUBMED   22500632
REFERENCE   7  (bases 1 to 1775)
  AUTHORS   Yamanaka,Y., Kitano,A., Takao,K., Prasansuklab,A., Mushiroda,T.,
            Yamazaki,K., Kumada,T., Shibata,M., Takaoka,Y., Awaya,T., Kato,T.,
            Abe,T., Iwata,N., Miyakawa,T., Nakamura,Y., Nakahata,T. and
            Heike,T.
  TITLE     Inactivation of fibroblast growth factor binding protein 3 causes
            anxiety-related behaviors
  JOURNAL   Mol Cell Neurosci 46 (1), 200-212 (2011)
   PUBMED   20851768
  REMARK    GeneRIF: These results demonstrate that FGF-BP3 is a potent
            mediator of anxiety-related behaviors in mice and suggest that
            distinct pathways regulate emotional behaviors.
REFERENCE   8  (bases 1 to 1775)
  AUTHORS   Kumada,T., Yamanaka,Y., Kitano,A., Shibata,M., Awaya,T., Kato,T.,
            Okawa,K., Abe,T., Oshima,N., Nakahata,T. and Heike,T.
  TITLE     Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic
            reticulum, is required for early embryonic development
  JOURNAL   Dev Dyn 239 (8), 2233-2245 (2010)
   PUBMED   20568244
REFERENCE   9  (bases 1 to 1775)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   10 (bases 1 to 1775)
  AUTHORS   Jukkola,T., Lahti,L., Naserke,T., Wurst,W. and Partanen,J.
  TITLE     FGF regulated gene-expression and neuronal differentiation in the
            developing midbrain-hindbrain region
  JOURNAL   Dev Biol 297 (1), 141-157 (2006)
   PUBMED   16782087
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC055778.1.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus based on the presence of an upstream translation start
            codon that is conserved in rodent species.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055778.1, AK167949.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1775              BC055778.1         1-1775
FEATURES             Location/Qualifiers
     source          1..1775
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 32.01 cM"
     gene            1..1775
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="fibroblast growth factor binding protein 3"
                     /db_xref="GeneID:72514"
                     /db_xref="MGI:MGI:1919764"
     exon            1..28
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /inference="alignment:Splign:2.1.0"
     exon            29..1756
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1231..1236
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="hexamer: ATTAAA"
     polyA_site      1260
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="major polyA site"
     regulatory      1401..1406
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="hexamer: AATAAA"
     polyA_site      1427
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="major polyA site"
     regulatory      1712..1717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
                     /note="hexamer: AACAAA"
     polyA_site      1754
                     /gene="Fgfbp3"
                     /gene_synonym="2610306H15Rik; Fgf-bp3"
ORIGIN      
        1 agggcccttc cacctcttct agaattcgat cctaggatgc tccttgcctc ctgttgcctg
       61 cgctgaggtc ccaggaatcc cagagtggca tggccaacgc gggcatgagt cctccgaggc
      121 cgcgggcgtc gctctccccg ctgacgctgc tgttgctgct gggaggctgc ctcctctcgg
      181 ctgccgggag ggacaagggg gcagcaggca gggaagtgac ccgggcctcc cgacccacgg
      241 tcggctcctc cggtcgcttc gtgagtccag agcagcacgc gtgcagctgg cagctcttgg
      301 tacccgcccc ggggacgccg actggcggag agctggcctt gcgctgccag accccgggcg
      361 gggcgagtct gcattgcgcc taccgcgggc atccggagcg ctgcgcggcc accggcgccc
      421 ggcgcgcgca ctactggaga cggctgctgg gcgcgctgcg caggagacca cggccctgcc
      481 tggaccccgc gccgctgccg ccacgcctgt gcgcccgcaa gacggctggc tcagacctgc
      541 actcgcccgc tcaccccagc ctacccgcgc gtcccagcga gccgccccgg tccagggcgc
      601 ggagcccggc tcggtcgcga cagtcggtgc ggtccccaag ctcccagccg gaaaagaagc
      661 ccttgctagt gaagtccaac tcgggcggga ggaaagcggg ctcagaccca gttccggagc
      721 ctcctgcggc ggccggattc caacccaatg ggctggacca gaatgccgag ctcactgaga
      781 cctactgcac cgagaagtgg cattcccttt gcaacttctt tgtcaacttc tggaatggct
      841 gaggctgcgg gctggcaagg ggcactaggg gtaggtgctg agaagcagag ggtagcgcag
      901 ccgaggcggg agatgtcctt ggacagggaa ccgggatgga gaataagcta gtcggctagt
      961 cgggattcca aaatgggtca ggggtcaggg taagaagaat ctgaagcagc tggagagggc
     1021 ttttgttttt tattttatgt ttatttttat tttttaaagc atctcagctc tgatttaaga
     1081 gcagaagaaa aagtggaaac aaatagattt atatcaagta tgggaaaatt gtagactagg
     1141 gagagaagct gagactagca agaatgaagt gactaaagag gtgagaatct ttcctaggaa
     1201 gtgggataca atgtatatca acacattttc attaaatgta actgtgagta agaacctgaa
     1261 ccatgttgaa tatttcaaga tcttcttggt tttcaacttg agaaaatgaa tacccaccca
     1321 cccccctttc tggattgtta tgaactctgg gtgtgactgg catcacactt tctatgtaga
     1381 ttaaaacctt ataggtaaat aataaatcta cgactggatt atcaggacaa ttgcttttca
     1441 gtccctttgc tactttttaa ctgaattttg agcctactgt ccagaaaagt tcattaacta
     1501 cctaaaatca gaagtgaatt ttagaagttc agtgctctct agatctccaa atacaaacaa
     1561 aaactccaag cctttaaatt ttgattactc tttttaaaat cagctaaaat gtaaacacgt
     1621 atctgggtca tttggccctt catctcttct gtgattaaat ttaaaatgtg tgtgtttttt
     1681 aaatatgttg taacaactgt ctttaattaa aaacaaaaaa aaaaactgat tggatttaaa
     1741 gagttgtaaa atgatgaaaa aaaaaaaaaa aaaaa
//
