LOCUS       NM_030610               1543 bp    mRNA    linear   ROD 31-DEC-2024
DEFINITION  Mus musculus fibroblast growth factor 20 (Fgf20), mRNA.
ACCESSION   NM_030610
VERSION     NM_030610.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1543)
  AUTHORS   Jin,Z., Liu,Z., Pan,J., Wang,S., Cui,M., He,C., Lin,M., Liu,X.,
            Yu,X. and Gong,F.
  TITLE     FGF20 modulates gut microbiota to mitigate dextran sodium
            sulfate-induced ulcerative colitis in mouse models
  JOURNAL   Int Immunopharmacol 142 (Pt A), 113044 (2024)
   PUBMED   39217880
  REMARK    GeneRIF: FGF20 modulates gut microbiota to mitigate dextran sodium
            sulfate-induced ulcerative colitis in mouse models.
REFERENCE   2  (bases 1 to 1543)
  AUTHORS   Dlugosova,S., Spoutil,F., Madureira Trufen,C.E., Melike Ogan,B.,
            Prochazkova,M., Fedosieieva,O., Nickl,P., Aranaz Novaliches,G.,
            Sedlacek,R. and Prochazka,J.
  TITLE     Skeletal dysmorphology and mineralization defects in Fgf20 KO mice
  JOURNAL   Front Endocrinol (Lausanne) 15, 1286365 (2024)
   PUBMED   39129916
  REMARK    GeneRIF: Skeletal dysmorphology and mineralization defects in Fgf20
            KO mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1543)
  AUTHORS   Adkins-Threats,M., Arimura,S., Huang,Y.Z., Divenko,M., To,S.,
            Mao,H., Zeng,Y., Hwang,J.Y., Burclaff,J.R., Jain,S. and Mills,J.C.
  TITLE     Metabolic regulator ERRgamma governs gastric stem cell
            differentiation into acid-secreting parietal cells
  JOURNAL   Cell Stem Cell 31 (6), 886-903 (2024)
   PUBMED   38733994
REFERENCE   4  (bases 1 to 1543)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 1543)
  AUTHORS   Villeneuve,C., Hashmi,A., Ylivinkka,I., Lawson-Keister,E.,
            Miroshnikova,Y.A., Perez-Gonzalez,C., Myllymaki,S.M., Bertillot,F.,
            Yadav,B., Zhang,T., Matic Vignjevic,D., Mikkola,M.L., Manning,M.L.
            and Wickstrom,S.A.
  TITLE     Mechanical forces across compartments coordinate cell shape and
            fate transitions to generate tissue architecture
  JOURNAL   Nat Cell Biol 26 (2), 207-218 (2024)
   PUBMED   38302719
REFERENCE   6  (bases 1 to 1543)
  AUTHORS   Hayashi,T., Ray,C.A. and Bermingham-McDonogh,O.
  TITLE     Fgf20 is required for sensory epithelial specification in the
            developing cochlea
  JOURNAL   J Neurosci 28 (23), 5991-5999 (2008)
   PUBMED   18524904
  REMARK    GeneRIF: Fgf20 is expressed at the right time and place to mediate
            sensory cell specification and is the likely activator/ligand of
            fibroblast growth factor (FGF) receptor 1 during cochlear
            development.
REFERENCE   7  (bases 1 to 1543)
  AUTHORS   Lavine,K.J., Yu,K., White,A.C., Zhang,X., Smith,C., Partanen,J. and
            Ornitz,D.M.
  TITLE     Endocardial and epicardial derived FGF signals regulate myocardial
            proliferation and differentiation in vivo
  JOURNAL   Dev Cell 8 (1), 85-95 (2005)
   PUBMED   15621532
REFERENCE   8  (bases 1 to 1543)
  AUTHORS   van der Walt,J.M., Noureddine,M.A., Kittappa,R., Hauser,M.A.,
            Scott,W.K., McKay,R., Zhang,F., Stajich,J.M., Fujiwara,K.,
            Scott,B.L., Pericak-Vance,M.A., Vance,J.M. and Martin,E.R.
  TITLE     Fibroblast growth factor 20 polymorphisms and haplotypes strongly
            influence risk of Parkinson disease
  JOURNAL   Am J Hum Genet 74 (6), 1121-1127 (2004)
   PUBMED   15122513
REFERENCE   9  (bases 1 to 1543)
  AUTHORS   Wright,T.J., Hatch,E.P., Karabagli,H., Karabagli,P.,
            Schoenwolf,G.C. and Mansour,S.L.
  TITLE     Expression of mouse fibroblast growth factor and fibroblast growth
            factor receptor genes during early inner ear development
  JOURNAL   Dev Dyn 228 (2), 267-272 (2003)
   PUBMED   14517998
REFERENCE   10 (bases 1 to 1543)
  AUTHORS   Hajihosseini,M.K. and Heath,J.K.
  TITLE     Expression patterns of fibroblast growth factors-18 and -20 in
            mouse embryos is suggestive of novel roles in calvarial and limb
            development
  JOURNAL   Mech Dev 113 (1), 79-83 (2002)
   PUBMED   11900978
  REMARK    GeneRIF: expression of FGF20 in calvarial and limb development
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160537.6.
            
            On Aug 29, 2022 this sequence version replaced NM_030610.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052233.1, SRR7345562.4251831.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-598               AC160537.6         32374-32971
            599-702             AC160537.6         38179-38282
            703-1543            AC160537.6         39388-40228
FEATURES             Location/Qualifiers
     source          1..1543
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 23.89 cM"
     gene            1..1543
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /note="fibroblast growth factor 20"
                     /db_xref="GeneID:80857"
                     /db_xref="MGI:MGI:1891346"
     exon            1..598
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            599..702
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            703..1543
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1525..1530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /note="hexamer: AATAAA"
     polyA_site      1543
                     /gene="Fgf20"
                     /gene_synonym="Fgf4a"
                     /note="major polyA site"
ORIGIN      
        1 gatctgatca gtttgctgag ctggagcctc agcccccagc tccagcccca aatcagcagc
       61 ctcagctcta gatgtttctg caaggccagc agccagcatc ctcctaccca aggagagaag
      121 atcaatctaa gagggtgcac tgcaccgtcc ccacagggac ctcacaggag taacccagcc
      181 ttaacttttt tggtacctat ttggctataa tttttctgca ttcgcctcgc cacccttgct
      241 acacttttta ttggcggtgc agagggaagt ctcctgtttt ctggaatttc agtcatcctg
      301 tccggcccgt ccatggctcc cttgaccgaa gtcggggctt tcttgggcgg cctggagggc
      361 ttgagccagc aggtggggtc gcacttcttg ctgcctcctg caggggagag gccaccgctg
      421 ttaggggagc ggcggggcgc gttggagagg ggcgcccgcg gcgggcccgg ttccgtggag
      481 ctggcgcacc tgcacggcat cctgcgccgc cggcagctct actgccgcac cggcttccac
      541 ctgcagatcc tgcccgacgg caccgtgcag ggcacccggc aggatcacag tctcttcggt
      601 atcctggaat tcatcagtgt ggcagtggga ctggtcagta tcagaggtgt ggacagtggc
      661 ctgtaccttg ggatgaatga caaaggagaa ctttatggat cagagaaatt gacttctgaa
      721 tgcatcttca gggaacaatt tgaagagaac tggtataata cctattcgtc caacatatat
      781 aaacatggag acacgggtcg caggtatttt gtagcactta acaaggatgg aactccaaga
      841 gatggtgcca ggtccaaaag acatcaaaag tttacccact ttttaccaag accagtagac
      901 ccagaaagag ttccagaatt atacaaagac ctactgatgt acacttgatg aatctagagc
      961 cattgtttaa aaatcacagt tcctgctgtt aaataacacc gaagaagacg ttcaggatat
     1021 tacgggagtc tgcttttcac tgaaagactc tatttgggaa gaaaattgag agtaaggaat
     1081 taacttgaag caaagcaaga tcattctccg taagtggatt gtagttcctt agacacgttg
     1141 tttcagtctt accagtagac tgacgatgct gaaatcagtt catctgcgga taatgtgaac
     1201 cttgctgctg acgccgcatg tctctggata atgtttactt ggacagttat cttaaaaata
     1261 gatacttcat gttgaagaag tggattgaga tgacataatt actgcctcat aaattctgag
     1321 gaccttgtag aaaggttaga acgttataca taaaacaaaa atcaaaatac tagatgactt
     1381 tgatctacaa accacaccac actgagatgg gacttttctt ttagaagaat ggacctattt
     1441 atactttttt caatttacaa atatttatta tatatattta tttattaaag agtttatttt
     1501 tactagtata tgaagactat acaaaataaa acaaacaaaa aga
//
