LOCUS       NM_080433               2304 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus Fez family zinc finger 2 (Fezf2), mRNA.
ACCESSION   NM_080433
VERSION     NM_080433.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2304)
  AUTHORS   Barao,S., Xu,Y., Llongueras,J.P., Vistein,R., Goff,L.,
            Nielsen,K.J., Bae,B.I., Smith,R.S., Walsh,C.A., Stein-O'Brien,G.
            and Muller,U.
  TITLE     Conserved transcriptional regulation by BRN1 and BRN2 in
            neocortical progenitors drives mammalian neural specification and
            neocortical expansion
  JOURNAL   Nat Commun 15 (1), 8043 (2024)
   PUBMED   39271675
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2304)
  AUTHORS   Tudi,A., Yao,M., Tang,F., Zhou,J., Li,A., Gong,H., Jiang,T. and
            Li,X.
  TITLE     Subregion preference in the long-range connectome of pyramidal
            neurons in the medial prefrontal cortex
  JOURNAL   BMC Biol 22 (1), 95 (2024)
   PUBMED   38679719
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2304)
  AUTHORS   Szelenyi,E.R., Fisenne,D., Knox,J.E., Harris,J.A., Gornet,J.A.,
            Palaniswamy,R., Kim,Y., Venkataraju,K.U. and Osten,P.
  TITLE     Distributed X chromosome inactivation in brain circuitry is
            associated with X-linked disease penetrance of behavior
  JOURNAL   Cell Rep 43 (4), 114068 (2024)
   PUBMED   38614085
REFERENCE   4  (bases 1 to 2304)
  AUTHORS   Ushio,A., Matsuda-Lennikov,M., Kalle-Youngoue,F., Shimizu,A.,
            Abdelmaksoud,A., Kelly,M.C., Ishimaru,N. and Takahama,Y.
  TITLE     Functionally diverse thymic medullary epithelial cells interplay to
            direct central tolerance
  JOURNAL   Cell Rep 43 (4), 114072 (2024)
   PUBMED   38581680
REFERENCE   5  (bases 1 to 2304)
  AUTHORS   Lammers,S., Barrera,V., Brennecke,P., Miller,C., Yoon,J.,
            Balolong,J., Anderson,M.S., Ho Sui,S., Steinmetz,L.M., von
            Andrian,U.H. and Rattay,K.
  TITLE     Ehf and Fezf2 regulate late medullary thymic epithelial cell and
            thymic tuft cell development
  JOURNAL   Front Immunol 14, 1277365 (2024)
   PUBMED   38420512
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2304)
  AUTHORS   Arlotta,P., Molyneaux,B.J., Chen,J., Inoue,J., Kominami,R. and
            Macklis,J.D.
  TITLE     Neuronal subtype-specific genes that control corticospinal motor
            neuron development in vivo
  JOURNAL   Neuron 45 (2), 207-221 (2005)
   PUBMED   15664173
REFERENCE   7  (bases 1 to 2304)
  AUTHORS   Hirata,T., Suda,Y., Nakao,K., Narimatsu,M., Hirano,T. and Hibi,M.
  TITLE     Zinc finger gene fez-like functions in the formation of subplate
            neurons and thalamocortical axons
  JOURNAL   Dev Dyn 230 (3), 546-556 (2004)
   PUBMED   15188439
  REMARK    GeneRIF: Fezl functions in the formation of subplate neurons and
            thalamocortical axons.
REFERENCE   8  (bases 1 to 2304)
  AUTHORS   Yang,Z., Liu,N. and Lin,S.
  TITLE     A zebrafish forebrain-specific zinc finger gene can induce ectopic
            dlx2 and dlx6 expression
  JOURNAL   Dev Biol 231 (1), 138-148 (2001)
   PUBMED   11180958
REFERENCE   9  (bases 1 to 2304)
  AUTHORS   Hashimoto,H., Yabe,T., Hirata,T., Shimizu,T., Bae,Y., Yamanaka,Y.,
            Hirano,T. and Hibi,M.
  TITLE     Expression of the zinc finger gene fez-like in zebrafish forebrain
  JOURNAL   Mech Dev 97 (1-2), 191-195 (2000)
   PUBMED   11025224
REFERENCE   10 (bases 1 to 2304)
  AUTHORS   Matsuo-Takasaki,M., Lim,J.H., Beanan,M.J., Sato,S.M. and
            Sargent,T.D.
  TITLE     Cloning and expression of a novel zinc finger gene, Fez,
            transcribed in the forebrain of Xenopus and mouse embryos
  JOURNAL   Mech Dev 93 (1-2), 201-204 (2000)
   PUBMED   10781957
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU703203.1, AK019996.1, AI325906.1 and BM963196.1.
            
            On Aug 21, 2009 this sequence version replaced NM_080433.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019996.1, ERR2680377.301178.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BU703203.1         95-131
            38-1617             AK019996.1         2-1581
            1618-1778           AI325906.1         268-428
            1779-2094           AK019996.1         1743-2058
            2095-2304           BM963196.1         268-477
FEATURES             Location/Qualifiers
     source          1..2304
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 6.36 cM"
     gene            1..2304
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /note="Fez family zinc finger 2"
                     /db_xref="GeneID:54713"
                     /db_xref="MGI:MGI:1859823"
     exon            1..279
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /inference="alignment:Splign:2.1.0"
     exon            280..1169
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..1700
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /note="forebrain embryonic zinc finger; forebrain
                     embryonic zinc finger-like protein 2; zinc finger protein
                     312"
                     /codon_start=1
                     /product="fez family zinc finger protein 2"
                     /protein_id="NP_536681.2"
                     /db_xref="CCDS:CCDS26818.1"
                     /db_xref="GeneID:54713"
                     /db_xref="MGI:MGI:1859823"
                     /translation="MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRA
                     PFEPRPAALEADSSQSKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSEFWKSSLRAG
                     GGGGGGSGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPA
                     SGSLYYFNYLDSTAYPPSELLGGHLFPSGLLNAQAPTSLAAHPKLFLLENAKLASLAA
                     DKFPHPASYPHKERLHAPLEQVLKENSALTAERGGVKSHSKLPGGSTDSKPKNFTCEV
                     CGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCG
                     KAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKA
                     FHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRKLHDSVGPTATPSAKDLA
                     RTVQS"
     exon            1170..1304
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1437
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..2304
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2092..2097
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /note="hexamer: AATAAA"
     polyA_site      2102
                     /gene="Fezf2"
                     /gene_synonym="Fez; Fezl; Zfp312"
                     /note="major polyA site"
ORIGIN      
        1 aaaccgctcg cactttcccg aagggagcgc gggcgctagt tgcctccttt aaagtttgag
       61 gggcggtggc ggcggccggc aggcgcgggg gaacgcaggg tcctcaacgg gagtcgcgcc
      121 gccgcccatg tcattccact tcaagtgact tcatgtgatg tcagctgaat gtaaaagaca
      181 gtgatctcac gcggagggga agatgtttgc catcaaaatg tgacagaaga gacacgctgc
      241 atggctcgga acgcatctcc ttggcggtgg gggaaagaga cttagaggag agaggctgtg
      301 ccctggccca gcctggccca gcttggcgcg ccatggccag ctcagcttcc ctggagacca
      361 tggtgccccc ggcctgcccg cgcgctggag cgtcaccggc cacttctaaa acactagctt
      421 tctctatcga gcgcatcatg gccaagacgt ccgagccccg agcgcctttc gagccccggc
      481 ctgctgcgtt agaggcagac agcagccaga gcaagaaact gctcaacctc tgctcgccgc
      541 tgccctgtat gatccctctc cagcctctag gctacgaggt gccgtccaag acgctgctca
      601 gttactcgga gttctggaag agcagcctcc gggcgggcgg cggtggagga ggaggcagcg
      661 gcgggggggc cccagtgtgc ggcgccagcg gcttgtgcaa aaccaactgt ggcgtgtgct
      721 gcaaggccga actgggcctc gcgccttctg cgctgcccgc cggcagggtc atcaaaccgc
      781 aggtcatcaa ccaggctgtg gggctgcctg ccagcggctc tctctactac ttcaactacc
      841 tggactccac cgcttaccca ccttcggagc tcctcggagg ccaccttttc ccatccggcc
      901 tcctcaacgc acaggccccc acttccctgg ctgctcaccc caagcttttt ctgctggaga
      961 acgccaaact ggccagcctg gctgcggaca agttccccca cccagcttcc tatccccata
     1021 aggagcgctt gcatgcgcca ctggagcagg tgctgaagga gaactcggcc ttgacagctg
     1081 aacgaggggg agtcaagagc cacagcaaac taccgggggg ctctactgac agcaaaccca
     1141 aaaacttcac ctgcgaagtg tgcggcaagg tgttcaatgc tcactataac ctcacccgcc
     1201 acatgcctgt ccacaccgga gctagaccgt ttgtgtgcaa agtctgtggc aaaggcttcc
     1261 gccaggccag cactctctgc agacacaaaa ttatccatac ccaggaaaaa ccacataagt
     1321 gtaaccagtg cggcaaagcc ttcaatcgca gctccacgct caacacgcac atccgcatcc
     1381 acgcgggcta caagcccttc gtctgcgagt tttgtggcaa aggctttcac caaaaaggga
     1441 actacaagaa tcacaagctc acccacagcg gcgagaagca gtacaaatgc actatctgta
     1501 acaaggcctt ccatcaggtc tacaatctga ccttccacat gcacacccac aacgacaaga
     1561 agcctttcac gtgtgccact tgcggcaaag gtttttgcag aaactttgac ttaaagaaac
     1621 atgtgcgcaa acttcatgac agcgtgggtc ccaccgccac cccctcagca aaggacctag
     1681 ccaggacagt tcagagctga gagctactgc cttgtccgtt cttcctgccc tgtaccaacc
     1741 caagcagatc tcacgtataa acttatttct aaaattaaaa gaaaaaaaaa ctatagcaga
     1801 gaggctaaaa tctatttatc gaaaccagca tatttttggg gaaatgtaaa cgtgtcctcg
     1861 atgaccggca caaacgcgtg gctcccacct ttgtacattc aggaaacgta tttaaatcca
     1921 gtgcgctgaa acatatttaa ttccaggcct ccgcttctcc tcaggcagcc ggcttttaat
     1981 cccagcctgt caccgtgagc gcccagaaga gcgtgatgcc cctgccatct tcactcaacc
     2041 ttgtaatctc tcctgtacaa gcgaacacgg aatattacat atatatgact caataaatag
     2101 aaccattagt gcgcgtcttc ttttccccat cccctcgcca cgaggtcagc tcaacaaatc
     2161 caaagaagga ggtggaacta agcatttata gcttttcctt tcccaaatgt aactttcttg
     2221 ggacaccggg gccaagctaa ggttaaaccg tactcctggt atgctggtat attaaagcac
     2281 ccaggagcat gggccgaaac actt
//
