LOCUS       NM_033522                886 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus Fer3 like bHLH transcription factor (Ferd3l), mRNA.
ACCESSION   NM_033522
VERSION     NM_033522.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Miozzo,F., Valencia-Alarcon,E.P., Stickley,L., Majcin Dorcikova,M.,
            Petrelli,F., Tas,D., Loncle,N., Nikonenko,I., Bou Dib,P. and
            Nagoshi,E.
  TITLE     Maintenance of mitochondrial integrity in midbrain dopaminergic
            neurons governed by a conserved developmental transcription factor
  JOURNAL   Nat Commun 13 (1), 1426 (2022)
   PUBMED   35301315
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  AUTHORS   Toledo,E.M., Yang,S., Gyllborg,D., van Wijk,K.E., Sinha,I.,
            Varas-Godoy,M., Grigsby,C.L., Lonnerberg,P., Islam,S.,
            Steffensen,K.R., Linnarsson,S. and Arenas,E.
  TITLE     Srebf1 Controls Midbrain Dopaminergic Neurogenesis
  JOURNAL   Cell Rep 31 (5), 107601 (2020)
   PUBMED   32375051
REFERENCE   3  (bases 1 to 886)
  AUTHORS   Metzakopian,E., Bouhali,K., Alvarez-Saavedra,M., Whitsett,J.A.,
            Picketts,D.J. and Ang,S.L.
  TITLE     Genome-wide characterisation of Foxa1 binding sites reveals several
            mechanisms for regulating neuronal differentiation in midbrain
            dopamine cells
  JOURNAL   Development 142 (7), 1315-1324 (2015)
   PUBMED   25804738
REFERENCE   4  (bases 1 to 886)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 886)
  AUTHORS   Mansour,A.A., Khazanov-Zisman,S., Netser,Y., Klar,A. and
            Ben-Arie,N.
  TITLE     Nato3 plays an integral role in dorsoventral patterning of the
            spinal cord by segregating floor plate/p3 fates via Nkx2.2
            suppression and Foxa2 maintenance
  JOURNAL   Development 141 (3), 574-584 (2014)
   PUBMED   24401371
  REMARK    GeneRIF: Nato3 induces ectopic Foxa2-positive cells and indirectly
            downregulates Nkx2.2 expression.
REFERENCE   6  (bases 1 to 886)
  AUTHORS   Ono,Y., Nakatani,T., Minaki,Y. and Kumai,M.
  TITLE     The basic helix-loop-helix transcription factor Nato3 controls
            neurogenic activity in mesencephalic floor plate cells
  JOURNAL   Development 137 (11), 1897-1906 (2010)
   PUBMED   20460368
  REMARK    GeneRIF: in the developing mesencephalon, loss of Nato3 did not
            affect floor plate (FP) differentiation, but led to loss of
            neurogenic activity in the medial subpopulation of mesFP cells by
            suppressing proneural gene expression and inducing cell cycle
            arrest
REFERENCE   7  (bases 1 to 886)
  AUTHORS   Stevens,J.D., Roalson,E.H. and Skinner,M.K.
  TITLE     Phylogenetic and expression analysis of the basic helix-loop-helix
            transcription factor gene family: genomic approach to cellular
            differentiation
  JOURNAL   Differentiation 76 (9), 1006-1022 (2008)
   PUBMED   18557763
REFERENCE   8  (bases 1 to 886)
  AUTHORS   Svard,J., Heby-Henricson,K., Persson-Lek,M., Rozell,B., Lauth,M.,
            Bergstrom,A., Ericson,J., Toftgard,R. and Teglund,S.
  TITLE     Genetic elimination of Suppressor of fused reveals an essential
            repressor function in the mammalian Hedgehog signaling pathway
  JOURNAL   Dev Cell 10 (2), 187-197 (2006)
   PUBMED   16459298
  REMARK    Erratum:[Dev Cell. 2006 Mar;10(3):409. Henricson, Karin Heby
            [corrected to Heby-Henricson, Karin]]
REFERENCE   9  (bases 1 to 886)
  AUTHORS   Verzi,M.P., Anderson,J.P., Dodou,E., Kelly,K.K., Greene,S.B.,
            North,B.J., Cripps,R.M. and Black,B.L.
  TITLE     N-twist, an evolutionarily conserved bHLH protein expressed in the
            developing CNS, functions as a transcriptional inhibitor
  JOURNAL   Dev Biol 249 (1), 174-190 (2002)
   PUBMED   12217327
REFERENCE   10 (bases 1 to 886)
  AUTHORS   Segev,E., Halachmi,N., Salzberg,A. and Ben-Arie,N.
  TITLE     Nato3 is an evolutionarily conserved bHLH transcription factor
            expressed in the CNS of Drosophila and mouse
  JOURNAL   Mech Dev 106 (1-2), 197-202 (2001)
   PUBMED   11472856
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF517121.1.
            
            On Jun 19, 2003 this sequence version replaced NM_033522.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF517121.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="129/Sv"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 14.79 cM"
     gene            1..886
                     /gene="Ferd3l"
                     /gene_synonym="bHLHa31; fer3; Mnato3; N-twist; Nato;
                     Nato3; Ntwist; Ptfb"
                     /note="Fer3 like bHLH transcription factor"
                     /db_xref="GeneID:114712"
                     /db_xref="MGI:MGI:2150010"
     exon            1..886
                     /gene="Ferd3l"
                     /gene_synonym="bHLHa31; fer3; Mnato3; N-twist; Nato;
                     Nato3; Ntwist; Ptfb"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..572
                     /gene="Ferd3l"
                     /gene_synonym="bHLHa31; fer3; Mnato3; N-twist; Nato;
                     Nato3; Ntwist; Ptfb"
                     /note="neuronal twist; nephew of atonal 3; Fer3-like;
                     basic helix-loop-helix protein N-twist; pancreas-specific
                     transcription factor b"
                     /codon_start=1
                     /product="fer3-like protein"
                     /protein_id="NP_277057.1"
                     /db_xref="CCDS:CCDS25878.1"
                     /db_xref="GeneID:114712"
                     /db_xref="MGI:MGI:2150010"
                     /translation="MAAYPESCLDATVLNFVADLSLASPRHPLLCEFPPGVPFGDRTL
                     GYREGRPGRLSQFDERYQEVEGDEVEYEDPEEEEEEGEGRGRVASLLGRPKRKRVITY
                     AQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLQ
                     SKEEKEAS"
ORIGIN      
        1 accaaggagc tctatcggca gctatgccat tcctgcaaga aaatcggtga gatagacgct
       61 gagtgatggc cgcctatcca gagagctgct tggatgctac cgtgctgaac ttcgtagcag
      121 atctctctct ggcctctccc agacaccctc ttctctgcga gttcccacct ggggtccctt
      181 ttggggaccg aacactgggg tacagagagg gaagacctgg gagactgtcg cagtttgatg
      241 aaagatatca ggaagtagag ggggacgaag tggaatatga ggacccagaa gaggaggaag
      301 aggagggaga ggggcgcggc agagtagcat ccttgctggg ccgccccaaa agaaaaagag
      361 ttattactta tgcccagcgc caggccgcca acattcgcga gaggaagagg atgttcaacc
      421 taaacgaggc cttcgaccag ctgcgcagaa aggtacccac cttcgcttat gagaagagac
      481 tgtcgaggat cgagaccctc cgcttggcca tcgtctacat ttccttcatg accgagctcc
      541 tgcagagcaa ggaggaaaag gaggccagct gagcggggag gggtgagccc aagagacact
      601 cccccgcctc atcgtgcttg gcggggtgcg tctggaaggc agaggggccg ctggccttct
      661 gaggcggggt ttgagatggt aaactcccca ctcgcggcag ctctgcagtg aataagttgg
      721 ggatccggca caataagggt ctagctgggc aggttgggag ttcccggggt caaggattta
      781 gggagttaga gcttcttgct tggagcaggt gggaaactgg tctgctcctc cacggacctc
      841 tggtgatctc tcctccttgc tccttttcaa cagtagaaat aataaa
//
