LOCUS       NP_001034913             174 aa            linear   ROD 04-FEB-2025
DEFINITION  ferredoxin-2, mitochondrial precursor [Mus musculus].
ACCESSION   NP_001034913 XP_914001 XP_995525
VERSION     NP_001034913.1
DBSOURCE    REFSEQ: accession NM_001039824.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 174)
  AUTHORS   Zhang,J., Zhang,Y., Mohibi,S., Perng,V., Bustamante,M., Shi,Y.,
            Nakajima,K., Chen,M. and Chen,X.
  TITLE     Ferredoxin 2 Is Critical for Tumor Suppression and Lipid
            Homeostasis but Dispensable for Embryonic Development
  JOURNAL   Am J Pathol (2024) In press
   PUBMED   39732391
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (residues 1 to 174)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (residues 1 to 174)
  AUTHORS   Boniecki,M.T., Freibert,S.A., Muhlenhoff,U., Lill,R. and Cygler,M.
  TITLE     Structure and functional dynamics of the mitochondrial Fe/S cluster
            synthesis complex
  JOURNAL   Nat Commun 8 (1), 1287 (2017)
   PUBMED   29097656
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 174)
  AUTHORS   Gakh,O., Ranatunga,W., Smith,D.Y. 4th, Ahlgren,E.C.,
            Al-Karadaghi,S., Thompson,J.R. and Isaya,G.
  TITLE     Architecture of the Human Mitochondrial Iron-Sulfur Cluster
            Assembly Machinery
  JOURNAL   J Biol Chem 291 (40), 21296-21321 (2016)
   PUBMED   27519411
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC061189.1, AK020979.1 and BF318146.1.
            
            On or before May 4, 2006 this sequence version replaced
            XP_995525.1, XP_914001.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK020979.1, AK008401.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.7 cM"
     Protein         1..174
                     /product="ferredoxin-2, mitochondrial precursor"
                     /note="adrenodoxin-like protein, mitochondrial;
                     ferredoxin-1-like protein; ferredoxin-2, mitochondrial;
                     ferredoxin 1-like"
                     /calculated_mol_wt=14398
     transit_peptide 1..43
                     /note="Mitochondrion. /evidence=ECO:0000255; propagated
                     from UniProtKB/Swiss-Prot (Q9CPW2.1)"
                     /calculated_mol_wt=4386
     Region          26..52
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CPW2.1)"
     mat_peptide     44..174
                     /product="Ferredoxin-2, mitochondrial. /id=PRO_0000325953"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CPW2.1)"
                     /calculated_mol_wt=14398
     Region          59..174
                     /region_name="PLN02593"
                     /note="adrenodoxin-like ferredoxin protein"
                     /db_xref="CDD:178203"
     Site            order(92..93,96,99,102..105,141..142)
                     /site_type="active"
                     /note="catalytic loop [active]"
                     /db_xref="CDD:238126"
     Site            order(96,102,105,142)
                     /site_type="other"
                     /note="iron binding site [ion binding]"
                     /db_xref="CDD:238126"
     CDS             1..174
                     /gene="Fdx2"
                     /gene_synonym="B230118G17Rik; Fdx1l"
                     /coded_by="NM_001039824.3:26..550"
                     /db_xref="CCDS:CCDS22892.1"
                     /db_xref="GeneID:68165"
                     /db_xref="MGI:MGI:1915415"
ORIGIN      
        1 maasmargvs arvllraagg swgpraghaa vtsrtfgttg errageeaad spelprdvvn
       61 vvfvdrsgkr ipvrgkvgdn vlylaqrhgv dlegaceasl acstchvyvs eahldllppp
      121 eereddmldm apllqensrl gcqivltpel egvefalpki trnfyvdghi pkph
//
