LOCUS       NM_001357661             438 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus Foxo1 corepressor (Fcor), mRNA.
ACCESSION   NM_001357661 NR_045271 XR_105181 XR_107980 XR_378678
VERSION     NM_001357661.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Kodani,N., Nakae,J., Kobayashi,M., Kikuchi,O., Kitamura,T. and
            Itoh,H.
  TITLE     FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx
            Expression
  JOURNAL   iScience 23 (1), 100798 (2020)
   PUBMED   31923647
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Nakae,J., Cao,Y., Hakuno,F., Takemori,H., Kawano,Y., Sekioka,R.,
            Abe,T., Kiyonari,H., Tanaka,T., Sakai,J., Takahashi,S. and Itoh,H.
  TITLE     Novel repressor regulates insulin sensitivity through interaction
            with Foxo1
  JOURNAL   EMBO J 31 (10), 2275-2295 (2012)
   PUBMED   22510882
  REMARK    GeneRIF: Taken together, these data suggest that FCoR is a novel
            repressor that regulates insulin sensitivity and energy metabolism
            in adipose tissue by acting to fine-tune Foxo1 activity.
REFERENCE   3  (bases 1 to 438)
  AUTHORS   Church,D.M., Goodstadt,L., Hillier,L.W., Zody,M.C., Goldstein,S.,
            She,X., Bult,C.J., Agarwala,R., Cherry,J.L., DiCuccio,M.,
            Hlavina,W., Kapustin,Y., Meric,P., Maglott,D., Birtle,Z.,
            Marques,A.C., Graves,T., Zhou,S., Teague,B., Potamousis,K.,
            Churas,C., Place,M., Herschleb,J., Runnheim,R., Forrest,D.,
            Amos-Landgraf,J., Schwartz,D.C., Cheng,Z., Lindblad-Toh,K.,
            Eichler,E.E. and Ponting,C.P.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087183.9, KY467484.1 and BX529613.1.
            
            On or before Nov 4, 2017 this sequence version replaced
            NR_045271.1, XR_378678.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX529613.1, AA261406.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AC087183.9         16946-17000         c
            56-421              KY467484.1         1-366
            422-438             BX529613.1         355-371
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 1.92 cM"
     gene            1..438
                     /gene="Fcor"
                     /gene_synonym="2400009B08Rik"
                     /note="Foxo1 corepressor"
                     /db_xref="GeneID:100503924"
                     /db_xref="MGI:MGI:1915484"
     exon            1..212
                     /gene="Fcor"
                     /gene_synonym="2400009B08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            213..424
                     /gene="Fcor"
                     /gene_synonym="2400009B08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      402..407
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fcor"
                     /gene_synonym="2400009B08Rik"
                     /note="hexamer: AATACA"
     polyA_site      424
                     /gene="Fcor"
                     /gene_synonym="2400009B08Rik"
                     /note="major polyA site"
ORIGIN      
        1 agaccccggg tttgcaagga tggatgggaa tgggcggtcc tacacgccgc catcaggaag
       61 agggctctgc ggaatgctta ggaggccctt ccaccagagc tgctccaggg ccgggacttc
      121 gagacttcca cttcaccacc gcaggaccat ccaaagcaga tagactggga gacgcagcgc
      181 agatacacag agaaaggatg agaccggtgc agtgtggtga tggtagtggt gagagagtct
      241 ttctacagag ccctggctct attggaactc tatatatcag gctggacttg aactcacaaa
      301 gatccacctg ctgctgcctc ctaaatgctg ggactaaagg catgtgctag catgcatagc
      361 ctaatgtaac tcccccgcct tctaccttca ctagcaagga caatacagag tcatctgagt
      421 ctgaaaaaaa aaaaaaaa
//
