LOCUS       NM_028715               3160 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus FCH domain only 1 (Fcho1), transcript variant 1, mRNA.
ACCESSION   NM_028715
VERSION     NM_028715.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3160)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3160)
  AUTHORS   Ritter,B., Murphy,S., Dokainish,H., Girard,M., Gudheti,M.V.,
            Kozlov,G., Halin,M., Philie,J., Jorgensen,E.M., Gehring,K. and
            McPherson,P.S.
  TITLE     NECAP 1 regulates AP-2 interactions to control vesicle size,
            number, and cargo during clathrin-mediated endocytosis
  JOURNAL   PLoS Biol 11 (10), e1001670 (2013)
   PUBMED   24130457
REFERENCE   3  (bases 1 to 3160)
  AUTHORS   Umasankar,P.K., Sanker,S., Thieman,J.R., Chakraborty,S.,
            Wendland,B., Tsang,M. and Traub,L.M.
  TITLE     Distinct and separable activities of the endocytic clathrin-coat
            components Fcho1/2 and AP-2 in developmental patterning
  JOURNAL   Nat Cell Biol 14 (5), 488-501 (2012)
   PUBMED   22484487
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY274600.1, AK137333.1, BU614854.1 and BY601220.1.
            
            On Aug 8, 2009 this sequence version replaced NM_028715.2.
            
            Transcript Variant: This variant (1) represents the shortest
            transcript and encodes the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032207.1, AK137333.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                BY274600.1         1-14
            15-1363             AK137333.1         2-1350
            1364-2187           AK137333.1         1352-2175
            2188-2591           BU614854.1         156-559
            2592-3029           AK137333.1         2583-3020
            3030-3153           AK137333.1         3022-3145
            3154-3160           BY601220.1         400-406
FEATURES             Location/Qualifiers
     source          1..3160
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.43 cM"
     gene            1..3160
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /note="FCH domain only 1"
                     /db_xref="GeneID:74015"
                     /db_xref="MGI:MGI:1921265"
     exon            1..49
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            50..90
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            91..143
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..2738
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /codon_start=1
                     /product="F-BAR domain only protein 1"
                     /protein_id="NP_082991.3"
                     /db_xref="CCDS:CCDS52588.1"
                     /db_xref="GeneID:74015"
                     /db_xref="MGI:MGI:1921265"
                     /translation="MSYFGEHFWGDKNHGFEVLYHCVKQGPVATKELADFIRERANIE
                     ETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKDVLRY
                     GEEQLKTHKKCKEEVLGTVDAVQMLSGVGQLLPKSRENYLSRCMDLERLRRENTSQKE
                     MDKAETKSKKAADSLRRSVDKYNSARADFEIKMLDSALRFQAMEEAHLQHMKALLGSY
                     AHSVEDTHVQIGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKPGPLDFDAYSSAAL
                     QEAMKRLRGAKAFRLPGLSRREPRASVDFLESDSGVPPEVDDEGFTVRPDISQNNGAE
                     PPRFSSSDSDFDDEEPRKFYVHIKPAPTRAVACSSEAAAAQLRATAGSLILPPGPGGT
                     MKRHSSRDTSGKPQRPRSAPRTGSCAEKPLASEEPLSKSLFGPPLESAFDHDDFTGSS
                     SLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPESWVPRPGTPQSPPTCRAQHPE
                     PRGLMPRAPSPGPWGPEGGADSLTPADPTREGLAATLRRPRSRKVSCPLTRSNGDLCR
                     SLSPSPLGSSAPTIPPDRPSFSTQMGHGISRGPSPVVLGSQDALPVATAFTEYVHAYF
                     RGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVNTAPVEHFQPNADLIFS
                     DPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPESVPLQMS
                     AHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEK
                     RFTWKLPDVCEAGGSGHLSASWQPQSGPSTPSPVAAQFTSEGATLSGLDLELLGGGYR
                     MSLVKRRFATGMYLVSC"
     exon            144..235
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            236..310
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            311..452
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            453..605
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            606..710
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            711..809
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            810..906
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            907..951
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1024
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1049
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1107
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1286
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1311
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1363
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1458
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1459..1701
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1808
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1896
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1897..2005
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2161
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2294
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2295..2494
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2550
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2551..2715
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..3160
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2880..2885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2901
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /note="major polyA site"
     regulatory      3134..3139
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
                     /note="hexamer: CATAAA"
     polyA_site      3152
                     /gene="Fcho1"
                     /gene_synonym="3322402E17Rik"
ORIGIN      
        1 ggagggcggg gcgcgggtct ggagcgcgca ggtagcgccg cgagaggcga tggagaaact
       61 gaggcacaga gctgagtgaa ttggagccag acagacgcag gacagaggcc accaggatgt
      121 cctattttgg ggaacatttt tggggcgaca aaaaccatgg ctttgaggtc ctctaccatt
      181 gtgtgaagca gggtcctgtg gccaccaagg agctggctga cttcattagg gaaagggcca
      241 acatcgagga gacatactcg aaggccatgg ccaaactctc caagctagcc agcaacggga
      301 cccccatggg gacctttgcc ccgctctggg aggtcttccg tgtgtcctcg gacaaactgg
      361 cactgtgcca cctggagctt actcggaagc tgcacgatct ccttaaggat gtgctgcgct
      421 acggcgagga gcagctcaag acccacaaga agtgtaagga ggaagttcta ggcactgtgg
      481 atgcagtgca gatgttgtca ggcgtcgggc agctcctgcc aaagtctcgc gagaattact
      541 tgagccgctg tatggacctg gagaggctgc gtagagagaa caccagccag aaggagatgg
      601 acaaggcaga aaccaaaagc aagaaggctg ccgacagcct gcggcgctct gtggataaat
      661 acaactcagc ccgagccgac tttgagatca agatgcttga ttcagccctg cgttttcagg
      721 ccatggagga ggcacatctg cagcacatga aggccttgct gggctcctat gcgcactctg
      781 tggaggacac ccatgtgcaa attgggcagg tgcatgagga atttaagcag aatgtggaaa
      841 atgtgacggt ggacatgctc ctcaggaaat ttgcagagag caagggcacc gggcgcgaga
      901 agcctgggcc tctggacttc gatgcataca gctcagctgc cctgcaggaa gcaatgaaac
      961 gtctccgtgg agccaaggct ttccgccttc caggattgag ccgtcgggag ccacgtgcat
     1021 ctgttgattt cctggagtct gactcagggg tgcctccaga ggtagatgac gaaggcttca
     1081 ctgtgcgccc cgatatatct cagaacaatg gggctgagcc cccacgcttc tcctctagtg
     1141 actctgattt tgacgatgag gagcctagaa agttctatgt tcacatcaag cccgccccca
     1201 cccgcgccgt ggcctgcagc tctgaggctg cagctgccca gctcagggcc acggctggca
     1261 gcctcatcct ccctccaggc ccagggggca ccatgaaacg tcattcatca cgggacactt
     1321 ctgggaagcc acagagacct cgttcggccc cacgcactgg cagttgcgca gagaagcccc
     1381 tggcctcgga ggagccacta tccaagagcc tctttgggcc gccgctggag tccgccttcg
     1441 accacgatga cttcacaggc tccagcagcc tgggcttcac atccagcccg tctcctttct
     1501 catcctcatc tccggagaat gtggaggact cgggcctgga ttctccgtca catgctgccc
     1561 ctggtccgtc acctgagtcc tgggtccccc ggccaggcac cccgcagagc ccacccacct
     1621 gcagggcaca gcaccctgag cccaggggcc taatgccccg tgcaccctca ccaggtccct
     1681 gggggcctga gggaggtgca gattcactga cgccggctga ccccaccagg gagggcctag
     1741 ctgccacact gagaagacca cggtccagga aagtgtcctg cccactcacc aggagcaatg
     1801 gggacctgtg ccggtcgctc agcccatccc cactgggatc ctctgccccc accatccccc
     1861 ccgatcggcc tagcttctcc acccagatgg gacatggcat ctcccgtggc cccagcccag
     1921 tggtcctggg atctcaggac gccctgcccg tggccacagc cttcactgag tatgtccatg
     1981 cctatttccg tggccacagc cccagttgcc tggctcgagt caccggggag ttaaccatga
     2041 ccttccctgc gggcattgtg cgtgtgttca gtggcacccc accaccacct gtcctcagct
     2101 tccggctggt gaacacggcc cctgtagaac acttccagcc caacgctgac ctgatcttca
     2161 gtgacccctc ccagagtgac ccggagacca aagacttctg gctgaatatg gcggcgctga
     2221 cggaggccct acagcaccag gctgagcaga accccaccgc ctcctactac aacctggtgc
     2281 tattgcggta ccagttctcc cgccctggac ctgagtcagt gcccctgcaa atgagcgccc
     2341 actggcagtg cgggcccaca ctcacgcggg tctcggtgga gtacagctac cgtgcgggcg
     2401 ccactgctgt gtccacgcca ctcactaatg tccagatcct cctgcccgtg ggggagccgg
     2461 tgaccagtgt gcggctgcag cctgcggcca cctggaacac agaggaaaag aggttcacgt
     2521 ggaagcttcc agatgtgtgt gaggcagggg gctcaggcca cctgtcagcc agttggcagc
     2581 cgcagtcggg gcccagcact cccagccccg tggccgcaca attcaccagt gagggcgcca
     2641 cgctgtctgg cctggacctg gagctgctag gtggtggcta ccgcatgtcc ctggtgaagc
     2701 ggagattcgc tacagggatg tacctcgtca gctgctgagg ttcctagtgc tggggactgc
     2761 ctgctctcct gcctctgccg gctcccccag gctggactcc gtggacagga acacccattt
     2821 cagcctggct cagccaactc ctccgtccac aagcaggccc tggcctttag tattctttaa
     2881 ataaacagtt ttctaacaaa ataaagagga atcctctttc cggttcagac cgggaaggat
     2941 ggggaggggg gaaggaggag ctgataccta ctgtgcggtt catctccagg gctgtgtgag
     3001 ctgcctattc ctgctgacac acagctaggc tacagggagg gagaagtaga tgaaccccta
     3061 gaacactgct tctccaccct cctaatgctg agacccttta atatacttac tcatgttgtg
     3121 gtgacccccc aaccataaaa ttatttcatt tctacttcat
//
