LOCUS       NM_001122603            7957 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Fc fragment of IgG binding protein (Fcgbp), mRNA.
ACCESSION   NM_001122603
VERSION     NM_001122603.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7957)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7957)
  AUTHORS   Ehrencrona,E., van der Post,S., Gallego,P., Recktenwald,C.V.,
            Rodriguez-Pineiro,A.M., Garcia-Bonete,M.J., Trillo-Muyo,S.,
            Backstrom,M., Hansson,G.C. and Johansson,M.E.V.
  TITLE     The IgGFc-binding protein FCGBP is secreted with all GDPH sequences
            cleaved but maintained by interfragment disulfide bonds
  JOURNAL   J Biol Chem 297 (1), 100871 (2021)
   PUBMED   34126068
REFERENCE   3  (bases 1 to 7957)
  AUTHORS   Haglin,S., Berghard,A. and Bohm,S.
  TITLE     Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons
            Activates Dormant Tissue-Specific Stem Cells and Accelerates
            Age-Related Metaplasia
  JOURNAL   J Neurosci 40 (21), 4116-4129 (2020)
   PUBMED   32385093
REFERENCE   4  (bases 1 to 7957)
  AUTHORS   Znalesniak,E.B., Fu,T., Salm,F., Handel,U. and Hoffmann,W.
  TITLE     Transcriptional Responses in the Murine Spleen after Toxoplasma
            gondii Infection: Inflammasome and Mucus-Associated Genes
  JOURNAL   Int J Mol Sci 18 (6), 1245 (2017)
   PUBMED   28604600
  REMARK    GeneRIF: Gkn3, Fcgbp, and Muc2 might be involved in the transient
            disruption of the splenic architecture and its reorganization,
            which is characteristic after Toxoplasma gondii infection.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7957)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   6  (bases 1 to 7957)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 7957)
  AUTHORS   Johansson,M.E., Thomsson,K.A. and Hansson,G.C.
  TITLE     Proteomic analyses of the two mucus layers of the colon barrier
            reveal that their main component, the Muc2 mucin, is strongly bound
            to the Fcgbp protein
  JOURNAL   J Proteome Res 8 (7), 3549-3557 (2009)
   PUBMED   19432394
  REMARK    GeneRIF: the Fcgbp protein is probably cleaved at GD/PH and
            covalently attached to Muc2 via one or several of its von
            Willebrand D domains
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077773.1, AC158220.4, AJ011416.1, AK040441.1 and EH108930.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous data.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-995               AK077773.1         2-996
            996-1600            AC158220.4         74709-75313         c
            1601-2168           AC158220.4         71270-71837         c
            2169-2678           AC158220.4         69455-69964         c
            2679-4024           AJ011416.1         14-1359
            4025-7926           AK040441.1         729-4630
            7927-7957           EH108930.1         6-36                c
FEATURES             Location/Qualifiers
     source          1..7957
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.26 cM"
     gene            1..7957
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /note="Fc fragment of IgG binding protein"
                     /db_xref="GeneID:215384"
                     /db_xref="MGI:MGI:2444336"
     exon            1..17
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            18..74
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..7771
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /note="IgG Fc binding protein"
                     /codon_start=1
                     /product="IgGFc-binding protein precursor"
                     /protein_id="NP_001116075.1"
                     /db_xref="CCDS:CCDS52159.1"
                     /db_xref="GeneID:215384"
                     /db_xref="MGI:MGI:2444336"
                     /translation="MGSPWKWWALWAGATLLWALLTPAEASCQGIQCASGQRCQMVSG
                     KARCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGSDETLPAFSVEAKNE
                     HRGSRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHKSGTR
                     GVIEMDFGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTPDLDQAPDAL
                     EFANSWKLDDGDYLCDDGCHNSCPSCTPGQTQHYKGDRLCGMLTLSTGPFSACHEFLD
                     PKPFLDDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRLPASCPMSCPANSC
                     YDPCSPACPPSCNSEAVPTNCSSRPCVEGCVCLPGFVASGGDCVPVSSCGCIYQGRLL
                     APGQEVFDDDRCRRRCTCDGATQKVTCRDTTGCPSGERCNVQNGLLGCYPDNFASCQA
                     SGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRGSQTVSYTRAVR
                     VVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVYRQGNDAIVSIDFGLTVTYN
                     WDAHVTAKVPSSYAKDVCGLCGNFNGNPDDDLALKGGGQASNVLDFGNSWQEEIIPGC
                     GATEPGDCPQLDSLVTQQIQDKKECGILADPEGPFRECHKLLNPQGAIRDCVYDLCLL
                     PGQSGPLCDALAAYAAACQAAGGTVHPWRSEELCPLTCPPNSHYEQCSYGCPLSCGDL
                     PVQGGCGSECREGCVCNEGFALSGESCVPLASCGCVHEGAYHAPGETFYPGPGCDSLC
                     HCEEGGLVSCEPSSCGPQEACQPSNGVLGCVAVGTTTCQASGDPHYVTFDGRRFDFMG
                     TCVYVLAQTCGNRPGLHQFTVLQENEAWGNGKVSVTKVITVLVANYTLRLEQSQWKVK
                     VNGVDTKLPVMLDGGKIRVSQHGSDVVIETDFGLRVAYDLVYYVRVTIPGNYYKQMCG
                     LCGDYNGDPKDDFQKPDGSQTTDPSDFGNSWEEAVPDSPCAPVPPCTGDDCDTECSPE
                     LQDKYHGEQFCGLLTSPTGPLAACHKLLDPQGPLQDCVFDLCLGGGNQSILCNIIHAY
                     VSACQAAGGQVEPWRTETFCPMECPPHSHYEVCADTCSLGCWALNTPQQCPEGCAEGC
                     ECDSGFLYNGKACVPIEQCGCYHNGVYYEPEESVLIENCQQHCVCQPGKGMMCQDHSC
                     KPGQVCEPSGGVLTCVTKDPCHGITCRPQETCKVQGGEGVCVPNYNSTCWLWGDPHYN
                     SFDGWSFDFQGTCNYLLAGTLCPGVNAEGLTPFTVTTKNENRGSPAVSYVRQVTVTTL
                     NTNISIHKNEIGKVRVNGVLMALPVYLAGGRISVINGGSKAVLETDFGLQVTYDWNWR
                     VDVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWHE
                     CQGSCPTCPEDRVEEYEGPGFCGPLAPGTGSPFTSCHAHVPPESFFKGCVLDVCLGGG
                     SKDILCQALAAYAAACQAAGIKIEDWRTQAGCEITCPDNSHYELCGPPCPASCPPPAR
                     HTAPTVCDGPCVEGCQCDEGFVLSADQCVPLDGGCGCWVNGTYYEAGTEFWADTTCSK
                     RCHCGPGGDSLVCKPASCGLGEECALLPSGEIGCQPTSITECQAWGDPHYTTLDGHRF
                     DFQGTCEYLLSAPCHEPPTGTEYFNVTVANEHRGSQAVSYTRSVTLQIYGLSLTLSAQ
                     WPRKLQVNGEFVALPFHLDQKLSVYISGADVVVNTASGVSLAFDGDSFVRLRVPAAYA
                     GTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGAPGCDQCEPEPCPKPCTPEEQEPFRG
                     PDACGIITAPEGPLAPCHSLVPPTQYFEACLLDACQVQGHPGGLCPAIATYVAACQAA
                     GAQLGEWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETICREGCVCDAGFV
                     LSGDTCVPVGQCGCLYQGRYYVLGATFYPGPECERLCECGPDGQVTCQEGADCEPYEE
                     CRIENGVQACHPTGCGHCLANGGLHYVTLDGRVYDLHGSCSYVLASVCHPKPGDEEFS
                     IVLEKNSAGDPQRVVVTVAGQVVGLARGPQVTVDGEVVTLPVATGHVSVTAEGRNIVL
                     QTNKGMKVLFDGDAHILMSIPSSFRGRLCGLCGNFNGNWSDDFVLPSGAVAPNVEAFG
                     TAWRAPGSSLGCGEGCGPQGCPVCLAEETQAYEKNDACGKIRDPHGPFAACHKVLSPL
                     EYFRQCVYDMCAHKGDKAYLCRSLAAYTAACQAAGAAVKPWRTDSVCPLQCPAHSHYS
                     ICTRSCQGSCAALSGLTGCTTRCFEGCECDDHFLLSHGVCIPAQDCGCVHNGQYMPVN
                     SSLMSSDCSERCFCSPNNGLTCHEAGCPSGHVCEIQAGVRECQAARGLCSISVGANLT
                     TFDGAHNAISSPGVYELSSRCPGLQKNVPWYRVLADVQPCHNNDKIVSKVHIFFQDGL
                     VTVIPSKGAWVNGLRVDLPATVLTSVSVRRMPDGSMLVHQKAGVTVWLGKDGLLDVMV
                     GDDLAAMLCGACGNFDGDQTNDAYGSQGKTPIEKWRAQDFSPCSN"
     exon            75..424
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..995
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1600
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..2168
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2761
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..3344
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3345..3544
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3545..3686
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3687..4024
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4025..4598
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4599..5215
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5216..5759
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5760..6331
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6332..6905
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            6906..7105
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            7106..7489
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            7490..7761
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            7762..7930
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7910..7915
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      7929
                     /gene="Fcgbp"
                     /gene_synonym="A430096B05Rik"
                     /note="major polyA site"
ORIGIN      
        1 agctcgggga cccgcagaca tgggatcccc gtggaaatgg tgggccctgt gggccggagc
       61 aaccctcctg tgggctctgc tcaccccagc agaggcatcc tgccaaggca ttcagtgtgc
      121 atctgggcag cgctgccaga tggtgagtgg gaaggccagg tgtgtggcag agtccacagc
      181 tgtctgccgt gcccagggtg atccccacta taccaccttc gatggccgtc ggtatgacat
      241 gatgggcact tgttcctaca ccatggctga actgtgtgga tcagatgaga ccctgccagc
      301 cttcagtgtg gaagccaaaa atgaacatcg gggcagccgc caagtctcct atgtgggctt
      361 ggtcacagtc tatgcctaca gccattctgt gtcgctggtt cgtggggaaa ttggcttcgt
      421 tcggatcgac aatcagcgct cccgcctccc tgcctctctg agtgagggtc gcctacgtgt
      481 gcacaaaagt ggaacacgag gtgtgataga gatggacttt gggctggtgg tcacctatga
      541 ctgggatggc caactgaccc tgagcctgcc caagcgcttc caagaccaag tgtgcgggct
      601 gtgcggcaac tataatggag accctgccga tgacttcctc acgcctgact tggaccaggc
      661 tcccgatgcc ttggaatttg caaatagctg gaagctggat gatggggact acctgtgtga
      721 tgatggctgc cacaactctt gtccctcctg caccccaggg cagacccaac actacaaggg
      781 agaccgtctc tgtggcatgc taactctgtc cacaggcccc ttctctgcct gccatgaatt
      841 cctggacccc aagcctttcc tagatgattg tgtgtttgac ctgtgtgtca ctggagggga
      901 gcgactcagc ctgtgccgga gccttagcgc ctatgcccag gcctgtgtag aactgggtgt
      961 cacccttgag aactggagat taccagccag ctgccccatg tcctgtccag ccaacagctg
     1021 ctatgatcct tgcagccctg cctgcccgcc ttcctgcaac tcagaagctg tgccgaccaa
     1081 ctgctcttct cgcccttgcg tggagggctg cgtgtgcctt ccaggcttcg tggccagtgg
     1141 tggtgattgt gtgcctgtct catcctgtgg gtgcatctac cagggtcgcc tgctggcccc
     1201 gggtcaggaa gtgtttgatg atgaccgatg ccgccgccgc tgcacctgtg atggagccac
     1261 tcagaaggtg acctgcaggg acacaacagg atgccctagt ggtgagcgct gcaatgtgca
     1321 gaatggcctc ctgggttgct acccagacaa tttcgccagc tgccaggcat ctggagaccc
     1381 gcactatgtg agcttcgatg gaaagcgctt tgactttatg ggtacctgca catacctgct
     1441 ggtgggctca tgcggccaga acgctgcgct gcctgccttt aaggtgctgg tggaaaatga
     1501 acaccgaggc agtcagaccg tgagctacac aagagctgtg cgtgtggtgg cccatggggt
     1561 agaagtggct gtgcgaaggg agaatcctgg aagagtgctg atagatggcg tccttcagta
     1621 cctgcccttc caggctgcag gtgggaagat tcaggtgtac cgccagggca atgatgctat
     1681 cgtgagcata gactttggct tgactgttac ctacaattgg gatgctcacg tgactgccaa
     1741 ggtgcccagc agctatgcta aagatgtgtg tgggctctgt gggaacttca atgggaaccc
     1801 agatgacgac ctggctctga agggtggagg ccaagcttcc aatgtattgg actttgggaa
     1861 cagctggcaa gaagagataa tacctgggtg tggagcaact gaacctggtg actgtcccca
     1921 attggactcc cttgtgaccc agcaaattca agacaaaaag gagtgtggaa tccttgctga
     1981 tcccgagggt ccattccggg agtgtcacaa gttgctgaac ccccagggtg ccatacgtga
     2041 ctgtgtctat gacctctgcc tgctgcctgg tcagtctggg ccactgtgtg atgcattggc
     2101 agcctatgct gctgcatgcc aggctgccgg gggcactgtg catccctgga ggagcgagga
     2161 actttgccca ctgacctgcc cacctaacag ccactatgag caatgttcct acggatgccc
     2221 actgtcctgt ggagacctgc cagtgcaggg aggctgtggc tcagaatgcc gagagggctg
     2281 tgtttgtaat gagggctttg ccctcagtgg tgagtcttgt gtgcctttgg cctcctgcgg
     2341 ctgtgtacac gagggcgcct atcacgcacc aggagaaacc ttctatcctg gacctggatg
     2401 cgattctctt tgccactgtg aggaaggtgg cctggtttcc tgcgagccct catcttgcgg
     2461 cccacaggag gcctgccaac catccaatgg agtcctgggg tgtgtggctg tgggcactac
     2521 tacctgccag gcatcaggag accctcatta cgtcaccttt gacggccgcc gctttgactt
     2581 catgggcacc tgtgtgtatg tgctagcgca aacctgtgga aaccggcctg gtctacacca
     2641 gttcactgtc ctgcaggaga atgaggcctg gggtaatggg aaagtcagtg tgaccaaggt
     2701 gatcaccgtc ctggtggcca actacaccct gcgcctggag cagagtcagt ggaaggtcaa
     2761 ggtgaacggt gtggacacga agctgcctgt gatgctggat ggaggcaaga tccgagtctc
     2821 ccagcacggg tccgacgtcg tgattgaaac cgactttggc ctgcgtgtgg cctatgacct
     2881 tgtgtactat gttcgggtaa ccatcccagg caactactac aagcagatgt gtggtctgtg
     2941 cggggattac aacggggacc ccaaggacga cttccagaag cccgacggct ctcagacaac
     3001 agaccccagt gactttggta actcctggga ggaagctgtg cccgactccc cctgcgcacc
     3061 agtgcctccc tgcacaggag atgactgtga caccgagtgc agccccgagc tgcaggacaa
     3121 atatcatggg gagcagttct gcgggctgct caccagcccc acagggccac tggctgcctg
     3181 ccacaagctg ctagaccccc agggtccctt acaagactgt gtctttgatc tctgcctggg
     3241 tggcggaaac cagagcattc tctgtaacat catccatgcc tacgtgagcg cctgccaggc
     3301 ggctgggggg caagtggagc catggaggac ggaaactttc tgtccaatgg agtgcccccc
     3361 tcacagccac tatgaggtct gtgcagacac ttgctccctg ggctgctggg ctctgaatac
     3421 accccagcag tgcccagaag ggtgtgctga gggctgtgaa tgtgactctg gcttcctgta
     3481 caacggcaaa gcctgcgtgc ccatcgagca atgtggctgc taccacaatg gggtctacta
     3541 tgagccagag gagtcagttc tcattgaaaa ctgccagcag cattgtgtgt gccaaccagg
     3601 caaaggcatg atgtgccagg atcatagctg caaaccagga caggtgtgcg agccctcagg
     3661 aggcgtcctg acctgcgtca ccaaagaccc atgccatggt atcacctgcc gaccacagga
     3721 gacctgcaaa gttcaaggtg gtgagggtgt gtgtgtgccc aactataatt ccacgtgttg
     3781 gctgtggggt gaccctcact acaactcctt cgatggctgg agctttgact tccagggcac
     3841 ctgcaactac ctgctggcag gaacgctctg tcctggggtc aatgccgagg gcctgactcc
     3901 cttcactgtc acaaccaaga atgagaaccg gggtagcccc gctgtgtcct acgtgagaca
     3961 ggtcactgtg accactctca acaccaacat ttccatccac aagaatgaga tcggcaaagt
     4021 ccgggtgaat ggagttctca tggccttgcc tgtgtacttg gctggtgggc ggatttcagt
     4081 gattaatgga ggctcaaagg ctgtgctgga gactgacttt gggcttcagg tcacctacga
     4141 ctggaactgg agagtagatg tcacgctgcc cagcagctac catggtgcag tgtgtgggct
     4201 ctgtggaaac atggacaaaa accatcaaaa tgaccaagtc ttccctaatg gcacaatggc
     4261 accctcaata cctacctggg gtggcagctg gcaagttcca gggtgggacc ctctttgttg
     4321 gcatgaatgt caagggtcct gtcccacatg cccagaggac cgagtggagg agtatgaggg
     4381 tcctggcttc tgtggacctc tggctcctgg tacagggagt cctttcacca gctgccatgc
     4441 ccatgtgcct cctgaaagct tcttcaaggg ctgtgtgctg gacgtctgcc tgggtggggg
     4501 cagcaaagac atactgtgcc aggcactggc tgcctatgct gctgcctgtc aagctgctgg
     4561 catcaaaatc gaggactgga ggactcaggc cggttgtgag atcacctgcc ctgacaacag
     4621 ccactatgag ctctgtggcc caccctgccc agccagctgc ccaccccctg cacgacacac
     4681 agccccaact gtatgtgacg ggccctgtgt ggagggatgc cagtgtgacg agggcttcgt
     4741 cctgagtgct gatcagtgtg ttcccctgga tggtggctgt ggctgctggg tcaatggcac
     4801 atactatgaa gcaggcaccg agttttgggc tgataccacc tgctctaaga ggtgtcattg
     4861 tggacctgga ggtgactcct tggtctgcaa gcctgccagc tgtgggctgg gtgaggagtg
     4921 tgccttgttg ccctctggag agatcggctg ccaacctaca agcataactg aatgccaagc
     4981 ctggggtgat ccccattaca ccaccctaga tgggcaccgg tttgacttcc aaggcacctg
     5041 cgagtacctg ctgagtgcac cctgccatga gccacccaca gggactgaat acttcaatgt
     5101 caccgtggct aatgagcaca ggggcagcca ggctgtcagc tacacacgaa gtgtcactct
     5161 gcagatctat ggcctcagct tgaccctcag tgcccaatgg cccaggaagc tacaggtgaa
     5221 cggagagttc gtggctctgc ccttccatct ggaccagaaa ctcagtgttt acataagtgg
     5281 agcagatgta gtagtgaaca ctgcttcggg ggtctccctg gcttttgacg gagacagttt
     5341 cgtgcgcctg cgcgtgcccg ctgcctatgc tggcaccctc tgtggcctgt gcggcaacta
     5401 caacaagaat cccaacgatg acctgactgc agtgggcggg aaacctgagg gctggaaagt
     5461 gggcggagct ccaggctgtg accaatgcga gcctgagcct tgcccaaaac cctgcacacc
     5521 tgaggaacaa gaacccttcc gcggtcccga cgcctgcggc attatcacgg cccccgaagg
     5581 cccactagcg ccctgccaca gccttgtgcc acccacgcag tacttcgagg cttgcttgct
     5641 ggacgcctgt caggttcagg gacatccagg tggcctctgt cctgctatag ccacctatgt
     5701 ggcagcatgt caagctgctg gggcccaact tggagaatgg agaaagccag acttctgtcc
     5761 cctccagtgc cctgcccaca gccactacca gctctgtggt gactcctgcc ctgtgagttg
     5821 cccgagcctc tccgcccctg tgggctgtga aaccatctgc cgtgagggct gtgtctgtga
     5881 tgctggcttc gtgctcagtg gtgacacctg tgtccctgtg ggccagtgtg gctgcctcta
     5941 ccaagggcgc tactatgtgt taggtgccac cttctaccca ggccctgagt gtgagcggct
     6001 ctgtgagtgc gggcctgatg gccaggtcac ctgccaggaa ggggcagact gtgagcccta
     6061 tgaggagtgc cggatagaga atggcgttca ggcctgtcat cccactggct gtggccactg
     6121 tctggccaac ggaggcctcc attatgtcac tcttgatgga cgggtgtatg atcttcatgg
     6181 ctcctgctcc tatgtcctgg ccagcgtctg tcacccaaaa cctggagatg aggagttctc
     6241 cattgtgctc gaaaagaact cagctggaga tccccagcgt gtggtggtga ccgtggcagg
     6301 ccaggttgtg ggcctggctc gagggccaca ggtgactgtg gatggtgaag tcgtgaccct
     6361 gcctgtggcc acaggccacg tgagtgtgac agccgaaggc agaaacatag ttctgcagac
     6421 aaacaaggga atgaaggttc tcttcgatgg cgatgcccac atcctcatgt ccatcccgag
     6481 ttccttccgt ggacgtctct gtggcctctg tgggaatttc aatgggaact ggagtgacga
     6541 ctttgtgctg cctagtggag cagtggcccc caacgtggag gcctttggaa ccgcatggcg
     6601 agctcccggc tcctccttgg gctgtggtga aggctgcggg ccccaaggct gcccagtgtg
     6661 cttggcagag gagacacaag catatgagaa aaatgatgcc tgtgggaaga tccgggaccc
     6721 ccacggcccc tttgcagctt gccacaaggt tctgagcccc ttggaatact tccgccaatg
     6781 tgtgtatgac atgtgtgccc ataagggtga caaagcctat ctctgccgta gcctggctgc
     6841 ttatactgca gcctgtcagg cagctggggc agcagtgaag ccctggagga cagacagcgt
     6901 ctgccctctc cagtgtcctg cccacagcca ctactccatc tgcacccgct cctgccaggg
     6961 ctcctgtgct gctctctctg gcctcactgg ctgcaccacc cgctgctttg aagggtgtga
     7021 gtgcgatgac cacttcctgc tctcccacgg tgtgtgcatt cctgcccagg actgcggctg
     7081 tgtccataac ggccaatata tgccggtgaa ctcttccctg atgtcctcag actgcagcga
     7141 gcgctgtttc tgctccccaa acaacggtct gacatgccat gaagctggct gcccatctgg
     7201 ccatgtctgt gagatccagg ctggagtccg agagtgccag gctgcccgtg gcctctgctc
     7261 catctctgtt ggagccaacc taactacctt tgatggagct cacaatgcca tcagctcccc
     7321 tggtgtctat gagctttctt ctcgatgccc gggactccaa aagaatgtgc cctggtaccg
     7381 agtgcttgct gatgtccagc cttgccacaa caatgacaag atcgtgagca aggtccacat
     7441 cttcttccag gatggcctgg tgactgtgat cccaagcaag ggtgcatggg tgaatggtct
     7501 ccgcgtggat ctcccagcta ctgtgttaac atctgtgtct gtgaggagga tgcccgacgg
     7561 ctccatgctt gtccaccaga aggctggggt cacggtgtgg cttggaaaag atgggcttct
     7621 ggatgtgatg gttggtgatg accttgcagc catgctgtgt ggggcctgtg gaaactttga
     7681 tggggaccaa accaacgacg catatggttc tcaggggaag acaccgatag agaagtggag
     7741 agcacaggac ttctccccat gttccaactg atcagtcacc actggcactg aaggcatcaa
     7801 gacctgctcc ctcccagaag ttacagtgat tggaagatgc cctgtgtgtc ccttccctgt
     7861 ccctccccct ttgctgagcc actgaggcca aacctgaaag cattgagtaa ataaatacct
     7921 agacacagag aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
