LOCUS       NM_010185                683 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus Fc receptor, IgE, high affinity I, gamma polypeptide
            (Fcer1g), mRNA.
ACCESSION   NM_010185
VERSION     NM_010185.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Stark,K., Kilani,B., Stockhausen,S., Busse,J., Schubert,I.,
            Tran,T.D., Gaertner,F., Leunig,A., Pekayvaz,K., Nicolai,L.,
            Fumagalli,V., Stermann,J., Stephan,F., David,C., Muller,M.B.,
            Heyman,B., Lux,A., da Palma Guerreiro,A., Frenzel,L.P.,
            Schmidt,C.Q., Dopler,A., Moser,M., Chandraratne,S., von Bruhl,M.L.,
            Lorenz,M., Korff,T., Rudelius,M., Popp,O., Kirchner,M., Mertins,P.,
            Nimmerjahn,F., Iannacone,M., Sperandio,M., Engelmann,B.,
            Verschoor,A. and Massberg,S.
  TITLE     Antibodies and complement are key drivers of thrombosis
  JOURNAL   Immunity 57 (9), 2140-2156 (2024)
   PUBMED   39226900
REFERENCE   2  (bases 1 to 683)
  AUTHORS   Huang,C., Zhu,W., Li,Q., Lei,Y., Chen,X., Liu,S., Chen,D.,
            Zhong,L., Gao,F., Fu,S., He,D., Li,J. and Xu,H.
  TITLE     Antibody Fc-receptor FcepsilonR1gamma stabilizes cell surface
            receptors in group 3 innate lymphoid cells and promotes
            anti-infection immunity
  JOURNAL   Nat Commun 15 (1), 5981 (2024)
   PUBMED   39013884
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 683)
  AUTHORS   Morimoto,K., Takahashi,R., Takahashi,G., Miyajima,M. and
            Nakajima,K.
  TITLE     Maternal immunoglobulins are distributed in the offspring's brain
            to support the maintenance of cortical interneurons in the
            postnatal period
  JOURNAL   Inflamm Regen 44 (1), 24 (2024)
   PUBMED   38750507
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 683)
  AUTHORS   Guan,X., Hu,R., Choi,Y., Srivats,S., Nabet,B.Y., Silva,J.,
            McGinnis,L., Hendricks,R., Nutsch,K., Banta,K.L., Duong,E.,
            Dunkle,A., Chang,P.S., Han,C.J., Mittman,S., Molden,N.,
            Daggumati,P., Connolly,W., Johnson,M., Abreu,D.R., Cho,B.C.,
            Italiano,A., Gil-Bazo,I., Felip,E., Mellman,I., Mariathasan,S.,
            Shames,D.S., Meng,R., Chiang,E.Y., Johnston,R.J. and Patil,N.S.
  TITLE     Anti-TIGIT antibody improves PD-L1 blockade through myeloid and
            Treg cells
  JOURNAL   Nature 627 (8004), 646-655 (2024)
   PUBMED   38418879
  REMARK    Erratum:[Nature. 2024 Mar;627(8005):E11. doi:
            10.1038/s41586-024-07280-9.. PMID: 38480897]
REFERENCE   5  (bases 1 to 683)
  AUTHORS   Garrison,A.R., Moresco,V., Zeng,X., Cline,C.R., Ward,M.D.,
            Ricks,K.M., Olschner,S.P., Cazares,L.H., Karaaslan,E.,
            Fitzpatrick,C.J., Bergeron,E., Pegan,S.D. and Golden,J.W.
  TITLE     Nucleocapsid protein-specific monoclonal antibodies protect mice
            against Crimean-Congo hemorrhagic fever virus
  JOURNAL   Nat Commun 15 (1), 1722 (2024)
   PUBMED   38409240
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 683)
  AUTHORS   Morse,H.C. 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   7  (bases 1 to 683)
  AUTHORS   Oakey,R.J., Watson,M.L. and Seldin,M.F.
  TITLE     Construction of a physical map on mouse and human chromosome 1:
            comparison of 13 Mb of mouse and 11 Mb of human DNA
  JOURNAL   Hum Mol Genet 1 (8), 613-620 (1992)
   PUBMED   1301170
REFERENCE   8  (bases 1 to 683)
  AUTHORS   Hupp,K., Siwarski,D., Mock,B.A. and Kinet,J.P.
  TITLE     Gene mapping of the three subunits of the high affinity FcR for IgE
            to mouse chromosomes 1 and 19
  JOURNAL   J Immunol 143 (11), 3787-3791 (1989)
   PUBMED   2531187
REFERENCE   9  (bases 1 to 683)
  AUTHORS   Ra,C., Jouvin,M.H. and Kinet,J.P.
  TITLE     Complete structure of the mouse mast cell receptor for IgE (Fc
            epsilon RI) and surface expression of chimeric receptors
            (rat-mouse-human) on transfected cells
  JOURNAL   J Biol Chem 264 (26), 15323-15327 (1989)
   PUBMED   2527850
REFERENCE   10 (bases 1 to 683)
  AUTHORS   Hibbs,M.L., Walker,I.D., Kirszbaum,L., Pietersz,G.A., Deacon,N.J.,
            Chambers,G.W., McKenzie,I.F. and Hogarth,P.M.
  TITLE     The murine Fc receptor for immunoglobulin: purification, partial
            amino acid sequence, and isolation of cDNA clones
  JOURNAL   Proc Natl Acad Sci U S A 83 (18), 6980-6984 (1986)
   PUBMED   2944118
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY173505.1, BE634435.1 and CK791068.1.
            
            On Apr 12, 2006 this sequence version replaced NM_010185.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034163.1, CB597667.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-370               BY173505.1         1-370
            371-583             BE634435.1         74-286              c
            584-683             CK791068.1         521-620
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 79.23 cM"
     gene            1..683
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /note="Fc receptor, IgE, high affinity I, gamma
                     polypeptide"
                     /db_xref="GeneID:14127"
                     /db_xref="MGI:MGI:95496"
     exon            1..153
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..365
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /note="high affinity immunoglobulin epsilon receptor
                     subunit gamma; fceRI gamma; fc-epsilon RI-gamma; igE Fc
                     receptor subunit gamma; Fc receptor gamma-chain"
                     /codon_start=1
                     /product="high affinity immunoglobulin epsilon receptor
                     subunit gamma precursor"
                     /protein_id="NP_034315.1"
                     /db_xref="CCDS:CCDS15483.1"
                     /db_xref="GeneID:14127"
                     /db_xref="MGI:MGI:95496"
                     /translation="MISAVILFLLLLVEQAAALGEPQLCYILDAVLFLYGIVLTLLYC
                     RLKIQVRKAAIASREKADAVYTGLNTRSQETYETLKHEKPPQ"
     exon            154..245
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /inference="alignment:Splign:2.1.0"
     exon            246..281
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /inference="alignment:Splign:2.1.0"
     exon            282..302
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /inference="alignment:Splign:2.1.0"
     exon            303..658
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      632..637
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /note="hexamer: AATAAA"
     polyA_site      653
                     /gene="Fcer1g"
                     /gene_synonym="CD23; Fce1g; FcepsilonRI; FcR-gamma;
                     FcRgamma; FcR[g]; Ly-50"
                     /note="major polyA site"
ORIGIN      
        1 ggagggaact gtggtcaggg aactgttcgt gggcacagct gcgcagttct gtcagcgcag
       61 cgcgatcacc agctcccagc gccgcagccc ccagcgcacc caggatgatc tcagccgtga
      121 tcttgttctt gctccttttg gtggaacaag cagccgccct gggagagccg cagctctgct
      181 atatcctgga tgctgtcctg tttttgtatg gtattgtcct taccctactc tactgtcgac
      241 tcaagatcca ggtccgaaag gcagctatag ccagccgtga gaaagcagat gctgtctaca
      301 cgggcctgaa cacccggagc caggagacat atgagactct gaagcatgag aaaccacccc
      361 agtagcttca gaacagacgt gcttggctgc attcttttcc cacttctaat tctctccgag
      421 ccctcttggt cacctctgtg ctttgaaggt tggctgacct tattcacata atgatgctag
      481 ctaggctcta catcagtgta cactggcagg tccccatctc cgttaaagac ttactcactg
      541 acatttctct tcttccagcc tcctttgctt catttctttt tccttccctg atcctcgact
      601 ctcactaaac aatggaaagg gattatcccc caataaagct gccagagacc tgactcaaaa
      661 aaaaaaaaaa aaaaaaaaaa aaa
//
