LOCUS       NM_010184               1026 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus Fc receptor, IgE, high affinity I, alpha polypeptide
            (Fcer1a), mRNA.
ACCESSION   NM_010184
VERSION     NM_010184.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Kimura,M., Ando,T., Kume,Y., Fukase,S., Matsuzawa,M., Kashiwagi,K.,
            Izawa,K., Kaitani,A., Nakano,N., Maeda,K., Ogawa,H., Okumura,K.,
            Nakao,S., Murakami,A., Ebihara,N. and Kitaura,J.
  TITLE     A nerve-goblet cell association promotes allergic conjunctivitis
            through rapid antigen passage
  JOURNAL   JCI Insight 8 (21), e168596 (2023)
   PUBMED   37819721
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1026)
  AUTHORS   Florsheim,E.B., Bachtel,N.D., Cullen,J.L., Lima,B.G.C.,
            Godazgar,M., Carvalho,F., Chatain,C.P., Zimmer,M.R., Zhang,C.,
            Gautier,G., Launay,P., Wang,A., Dietrich,M.O. and Medzhitov,R.
  TITLE     Immune sensing of food allergens promotes avoidance behaviour
  JOURNAL   Nature 620 (7974), 643-650 (2023)
   PUBMED   37437602
REFERENCE   3  (bases 1 to 1026)
  AUTHORS   Tang,R.Y., Yin,L., Yao,L., Zhang,Q.F. and Chen,X.P.
  TITLE     A Co-Expressed Natural Antisense RNA FCER1A-AS Controls
            IgE-Dependent Immunity by Promoting Expression of FcepsilonRIalpha
  JOURNAL   Microbiol Spectr 11 (3), e0073323 (2023)
   PUBMED   37154775
  REMARK    GeneRIF: A Co-Expressed Natural Antisense RNA FCER1A-AS Controls
            IgE-Dependent Immunity by Promoting Expression of FcepsilonRIalpha.
REFERENCE   4  (bases 1 to 1026)
  AUTHORS   Choi,Y.A., Dhakal,H., Lee,S., Kim,N., Lee,B., Kwon,T.K., Khang,D.
            and Kim,S.H.
  TITLE     IRF3 Activation in Mast Cells Promotes FcepsilonRI-Mediated
            Allergic Inflammation
  JOURNAL   Cells 12 (11), 1493 (2023)
   PUBMED   37296614
  REMARK    GeneRIF: IRF3 Activation in Mast Cells Promotes
            FcepsilonRI-Mediated Allergic Inflammation.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1026)
  AUTHORS   Zhou,C., Li,M., Liu,Y., Wang,X., Zhang,S., Guan,L., Hong,J.,
            Zhou,W., Wu,G., Diao,W., Huang,Q. and Yang,P.
  TITLE     Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by
            modulating the expression of FcepsilonRI in mast cells
  JOURNAL   Clin Exp Immunol 211 (1), 15-22 (2023)
   PUBMED   36368013
  REMARK    GeneRIF: Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal
            allergy by modulating the expression of FcepsilonRI in mast cells.
REFERENCE   6  (bases 1 to 1026)
  AUTHORS   Oakey,R.J., Watson,M.L. and Seldin,M.F.
  TITLE     Construction of a physical map on mouse and human chromosome 1:
            comparison of 13 Mb of mouse and 11 Mb of human DNA
  JOURNAL   Hum Mol Genet 1 (8), 613-620 (1992)
   PUBMED   1301170
REFERENCE   7  (bases 1 to 1026)
  AUTHORS   Ye,Z.S., Kinet,J.P. and Paul,W.E.
  TITLE     Structure of the gene for the alpha-chain of the mouse high
            affinity receptor for IgE (Fc epsilon RI)
  JOURNAL   J Immunol 149 (3), 897-900 (1992)
   PUBMED   1386095
REFERENCE   8  (bases 1 to 1026)
  AUTHORS   Robertson,M.W., Mehl,V.S., Richards,M.L. and Liu,F.T.
  TITLE     mRNA variants encoding multiple forms of the high-affinity IgE
            receptor alpha subunit in transformed and nontransformed mast cells
  JOURNAL   Int Arch Allergy Appl Immunol 96 (4), 289-295 (1991)
   PUBMED   1839735
REFERENCE   9  (bases 1 to 1026)
  AUTHORS   Wong,Y.W., Williams,A.F., Kingsmore,S.F. and Seldin,M.F.
  TITLE     Structure, expression, and genetic linkage of the mouse BCM1 (OX45
            or Blast-1) antigen. Evidence for genetic duplication giving rise
            to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on
            mouse chromosome 3
  JOURNAL   J Exp Med 171 (6), 2115-2130 (1990)
   PUBMED   1693656
REFERENCE   10 (bases 1 to 1026)
  AUTHORS   Ra,C., Jouvin,M.H. and Kinet,J.P.
  TITLE     Complete structure of the mouse mast cell receptor for IgE (Fc
            epsilon RI) and surface expression of chimeric receptors
            (rat-mouse-human) on transfected cells
  JOURNAL   J Biol Chem 264 (26), 15323-15327 (1989)
   PUBMED   2527850
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ142191.1, BC125455.1, CJ142154.1, J05018.1 and BY585428.1.
            
            On Apr 15, 2009 this sequence version replaced NM_010184.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J05018.1, BC125455.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849380,
                                           SAMN00849387 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                CJ142191.1         1-35
            36-414              BC125455.1         1-379
            415-598             CJ142154.1         336-519
            599-904             BC125455.1         564-869
            905-1013            J05018.1           890-998
            1014-1026           BY585428.1         424-436
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 80.33 cM"
     gene            1..1026
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /note="Fc receptor, IgE, high affinity I, alpha
                     polypeptide"
                     /db_xref="GeneID:14125"
                     /db_xref="MGI:MGI:95494"
     exon            1..103
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /inference="alignment:Splign:2.1.0"
     exon            104..124
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /inference="alignment:Splign:2.1.0"
     exon            125..382
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /inference="alignment:Splign:2.1.0"
     exon            383..637
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /inference="alignment:Splign:2.1.0"
     exon            638..1026
                     /gene="Fcer1a"
                     /gene_synonym="Fce1a; fcepsilonri; FcERI; Fcr-5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tattttcgaa gccatagctc tctggtgcag ttagcacctg aaggtgcagg ggcgatggtc
       61 actggaaggt ctgcccagct gtgcctagca ctgctgttca tgtctcttga tgtcattctg
      121 acagccactg agaaatctgt actgaccttg gacccaccat ggattagaat atttacagga
      181 gagaaagtga ccctttcctg ctatgggaac aatcaccttc aaatgaactc tactactaaa
      241 tggatccaca atggtaccgt ctctgaggtg aactcttcac atttggtcat tgtgagtgcc
      301 accgttcaag acagtggaaa atacatatgt cagaagcaag gattgtttaa gagtaaacct
      361 gtgtacttga atgtaacgca agattggctg ctccttcaga catctgctga catggtctta
      421 gtccatggat cctttgacat cagatgccat ggctggaaga actggaatgt ccgcaaggtg
      481 atctactaca ggaatgacca tgctttcaac tacagttatg agagccccgt ctccattaga
      541 gaggccacac tgaatgacag tggcacctac cactgcaagg gctatcttag gcaggtgaaa
      601 tatgaatctg acaaattcag aattgctgta gtaaaagctt acaaatgcaa gtattattgg
      661 ctacaactaa ttttcccatt gttggtggcg attctgtttg ctgtggacac ggggttattg
      721 ctctcaaccg aagaacagtt caaatcagtc ttggagattc agaagactgg aaaatacaag
      781 aaagttgaaa ccgaactcct aacctagata catataggaa ctaatgtcat tgctgaagaa
      841 gcaattctta acagtaattt tctgcagaat cctcaatagc ttctccactg tcaaaggcca
      901 ctcatgtgat ccctagaaaa gtctgttcca caggaattgc ataaatgctt cattaaacca
      961 actgcagctg gttatgtaac atgcaataaa tagcaaatac tcaataaaca ctgccttaat
     1021 aagtta
//
