LOCUS       NM_026791               1866 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus F-box and WD-40 domain protein 9 (Fbxw9), mRNA.
ACCESSION   NM_026791
VERSION     NM_026791.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1866)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 1866)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1866)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   5  (bases 1 to 1866)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP769909.1, BB870341.1, CF197934.1 and BC060082.1.
            
            On Jan 27, 2007 this sequence version replaced NM_026791.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC043658.1, SRR1660815.531946.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-557               BP769909.1         24-580
            558-643             BB870341.1         169-254
            644-896             CF197934.1         48-300
            897-1866            BC060082.1         128-1097
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 41.54 cM"
     gene            1..1866
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /note="F-box and WD-40 domain protein 9"
                     /db_xref="GeneID:68628"
                     /db_xref="MGI:MGI:1915878"
     exon            1..418
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..1386
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /codon_start=1
                     /product="F-box/WD repeat-containing protein 9"
                     /protein_id="NP_081067.2"
                     /db_xref="CCDS:CCDS40418.1"
                     /db_xref="GeneID:68628"
                     /db_xref="MGI:MGI:1915878"
                     /translation="MDLSSGRSGDPRSCEEESDPEPDPDPDTQAEAYVARVLTPPKLG
                     LTPRRSSLQSMFSASLGVPERKAASKVPAVRLPGLLSLPPELLLEICAYLDARVVLQV
                     LPCVCQALHDLVRDRVTWRLRAQRRVRAPYPVVEEENFDWPAACIELEQHLARWAEDG
                     QRTEYFCLADGHFASIDAVLLLQGGALCLSGSRDRNVNLWDLRHLGKDPSRVLVKALG
                     TQGNSTHKGWVWSLAAQDHRVCSGSWDSTVKLWDMAADGQQFGEIKGKAAVLCLSYQP
                     DILVTGTYDKKVTIYDPRAGLALVKSRRLHSSAVLAVLADDRHVISGSEDHSLVVFDR
                     RANSVLQRLQLDSYLLCMSYQEPQLWAGDNQGLLHVFANRDGCFQLVRSFDVGHQSQI
                     TGIKHSLGTLYTTSTDKTIRVHVPTDPPRTICTRSHHNVLNGICAEGNVVVAASGGLS
                     LEVWRLLA"
     exon            419..558
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            559..687
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            688..800
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            801..892
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1041
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1155
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1245
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1311
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1843
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1817..1822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /note="hexamer: AATAAA"
     polyA_site      1843
                     /gene="Fbxw9"
                     /gene_synonym="1110017H11Rik; Fbw9"
                     /note="major polyA site"
ORIGIN      
        1 ccgggcgcca tggatctttc ctcagggcgg agtggggatc ctcgctcttg tgaggaggaa
       61 tctgaccccg agccagatcc cgaccctgac actcaagctg aggcctacgt agcccgtgtg
      121 cttacccctc ccaagcttgg cctgaccccg cggcgctcgt cactgcagtc catgttctcc
      181 gcgtccctag gcgtgccgga gcgaaaggcc gcctccaaag tcccggccgt gcgcctaccg
      241 ggcctcttga gccttccccc ggagctgctg ctggagatct gtgcctacct ggatgcgcga
      301 gtcgtgcttc aagtcctgcc gtgcgtgtgc caagcgttgc acgacctcgt gcgtgatcgt
      361 gtcacctgga ggctacgcgc tcagcgccgc gtacgcgcac cctacccagt ggtggaagag
      421 gagaactttg actggccagc cgcctgcatt gagctggagc agcacctggc ccgctgggca
      481 gaggatggac agcgaaccga gtacttctgc ctggctgatg gccactttgc ttccattgat
      541 gcggtgttgc tgctccaggg tggggcactg tgtctgtcag gctcccggga tcggaatgtc
      601 aacctgtggg acctgcgcca tctagggaag gatcccagcc gagttctggt gaaggcctta
      661 ggcacccagg gcaatagcac acacaagggc tgggtatggt cgctagcagc gcaggaccac
      721 cgtgtgtgct ccggctcttg ggacagcact gtgaagctgt gggacatggc ggctgatggg
      781 cagcagtttg gagagatcaa gggcaaggcg gcagtgctgt gcctttccta ccaacctgat
      841 atcctggtga ctggtaccta tgacaagaag gtgaccatct atgatcccag agctggtttg
      901 gccctggtga agagccggag gctgcactca agcgcggtgc tagcagtgct ggcagatgac
      961 aggcatgtca tctcaggcag cgaggaccac agccttgtgg tatttgatcg tcgagccaat
     1021 agcgtcctac agcggctgca gctggactcc tatctcctgt gcatgtctta ccaggagccc
     1081 cagctctggg caggtgacaa ccagggtctg ctgcacgtct tcgccaatcg agatggttgc
     1141 ttccagcttg ttcggtcctt tgatgtgggt caccagtctc agatcacagg gatcaaacac
     1201 tcgctgggga ctttgtacac aacatctact gacaagacca ttcgggttca cgtgcccaca
     1261 gatccaccta ggaccatctg tacccgaagc caccacaacg tgttaaatgg gatctgtgct
     1321 gagggcaacg tagtggtggc tgcctctggt ggcctgtcat tggaggtctg gaggctgctg
     1381 gcctgaagag ctagctggac gcggctgtgg atggatgttg gtatagactg cctgctgagg
     1441 ctgcaccgag gcctctgctc tggaggaatt cctgccattg gtgctgccct gctccacaga
     1501 cctgggatac aggaagtccc agggctgggc ccacactgtg cctgcagggg tgacattcta
     1561 gttttcctac caagagggtt cttccctacc ttccactcgt gggctttgcg ttttgttttg
     1621 ttttgttttg ttttgttgag acagggtctc atgtaaccca ggctggcctc atattcacta
     1681 tgtgtttgag gcaggccttg aatgcctgat ccccttgctt atatctccca cgtgttggga
     1741 tggtaggtgt gccaccatgc ctgaatgacc cattttgttt ggatttggat gtctctctcc
     1801 cacagcagtg aagagaaata aacctacgtg caattgttgg aaaaaaaaaa aaaaaaaaaa
     1861 aaaaaa
//
