LOCUS       NM_001378643            1490 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus F-box and WD-40 domain protein 25 (Fbxw25), mRNA.
ACCESSION   NM_001378643
VERSION     NM_001378643.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1490)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK143305.1 and CT025661.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143305.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-442               AK143305.1         1-442
            443-652             CT025661.8         133330-133539
            653-748             CT025661.8         135066-135161
            749-1490            AK143305.1         748-1489
FEATURES             Location/Qualifiers
     source          1..1490
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.69 cM"
     gene            1..1490
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /note="F-box and WD-40 domain protein 25"
                     /db_xref="GeneID:546160"
                     /db_xref="MGI:MGI:3588266"
     exon            1..121
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1432
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /codon_start=1
                     /product="F-box and WD-40 domain protein 25"
                     /protein_id="NP_001365572.1"
                     /db_xref="GeneID:546160"
                     /db_xref="MGI:MGI:3588266"
                     /translation="MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRK
                     LCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGY
                     ACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDM
                     HIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIF
                     RIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAP
                     VSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLI
                     ASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDP
                     VHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRD
                     GHGPYSLIAYALNICS"
     exon            122..159
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            160..323
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            324..442
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            443..652
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            653..811
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1022
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1201
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1326
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1490
                     /gene="Fbxw25"
                     /gene_synonym="E330001B16Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagagtcag tgtggactta ggccactaaa gatggagatc catttgccta gtttgcctat
       61 gctgaaaatc ctctcctatc tggatgccta caatttgcta caggctgccc aagtgaacaa
      121 gaactggaat gcacttgcca gcagtgatgt cctgtggagg aaattgtgtc agaggagatg
      181 gcactattgt gacatggtca ccctacagct ccagggcaaa gagacatgga agcagttctt
      241 catttaccga atatggcaag aacacgccaa gacccgggca aagccagaag atttcactta
      301 caaggaaatt cctgtggagt gtggatttta tggatacgca tgttatatct cagggcatgg
      361 tttaacaaga aacggacaag gcaagtcagt catctgtatg gtgagttcca agaacacgat
      421 ttccacctgg gatattcaca agagcgttat aacctgggta agcccagtac agccagcaag
      481 tatcaacctg ttgactaccc tccctgatat gcacattgcg gtcactgtag atattcaatc
      541 aactatcaaa ctgtgggact gtcacaacag ggaagctctg gcgactaaca acctggaatc
      601 tccatgtaaa tcactgaaag ctgtcatttc caaggatggc ccaattgtct tggtaggcga
      661 taccttgggt aacctctaca tctttaggat tccagattta cacctcattt ccacagtcaa
      721 tgtattccca tatggttttg atgaaattga ttgctctcct cagaagaaat gggtcttact
      781 tagtaagaac tacccacata ttttgccaaa ggtgttttac atgagcagcc tactgaggac
      841 atcagaattc tcagcccctg tgtctaccat tctcgaattt tccttatgcc aaggagcctt
      901 ctggacacca agaagggaag acaggataac cctgatgtcc agaagtggtt tcccccaaat
      961 cacaaagttt gaaacatttg atatgaagct ggaagggatc gggaacaaag tagctgttca
     1021 aggaaaattg atagcaagct tcttcttgcc atattatgag gagagcccca actggattgg
     1081 tgtcagtgat aaggatgtga ttgtttgttc aactcacttc tttctcttgc tctttaccat
     1141 caatggtctc catctgcaga catttcagta ctgcccagaa acgatcgtga gactctgtgt
     1201 ggaccctgtt catgtcatcg tcacctgtaa caatggctct ttggatgtat atgcatggga
     1261 ggagagaagc ctgttgctca ggaagtgtta tcgactgcaa aataagagac ctctgccact
     1321 gtacggcttc attaacaatt tgctatgtga cgatgtgagc atagttcagt tgatgagaga
     1381 tggtcatggc ccctactctc tgattgcata tgccttgaac atctgctctt gaaaactgag
     1441 tgggttgtgt gtctcttcct caatgataat aaaggtctat ttgcaagccc
//
