LOCUS       NM_001008428            1511 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus F-box and WD-40 domain protein 20 (Fbxw20), mRNA.
ACCESSION   NM_001008428 XM_486263
VERSION     NM_001008428.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1511)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1511)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ076686.1 and BC085247.1.
            
            On Mar 13, 2013 this sequence version replaced NM_001008428.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085247.1, AK136200.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                CJ076686.1         1-30
            31-1511             BC085247.1         12-1492
FEATURES             Location/Qualifiers
     source          1..1511
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.63 cM"
     gene            1..1511
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /note="F-box and WD-40 domain protein 20"
                     /db_xref="GeneID:434440"
                     /db_xref="MGI:MGI:3584372"
     exon            1..142
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1459
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /note="F-box and WD-40 domain protein 12"
                     /codon_start=1
                     /product="F-box and WD-40 domain protein 20"
                     /protein_id="NP_001008428.1"
                     /db_xref="CCDS:CCDS23549.1"
                     /db_xref="GeneID:434440"
                     /db_xref="MGI:MGI:3584372"
                     /translation="MEVHLPRLPLMKIFSYLDAYSLLQAAQVNKNWNELASSDVLWRK
                     LCQKRWLFCDMVTLQLLGTETWKQFFVFRTWQEHAKTRAKPEDFTYKEIPAEYGFRAN
                     ACYISGCGLTRNVQDRSVICMVSSMTKLSTWDIREGIMTWVSTEQPAYIKLLTTLPEM
                     HIAVTVDTHSTIKLWDCHNREALATNCLFSSCKLLKAVFSKDDPIVLVGDISGNLYIF
                     RIPDLHLISKVNVFPYGIDELHCSPQKKWVFLIMKHPRVLTKVVYMNSLLRTSEFSAP
                     VSTILKFSLCDKAFWTPRREDRITQMSRGVPPRPTKFATFDMKLEEIGNKVTVQEYLV
                     ASFSLQDYEASPEWMGVSNKDVIVCSTGSSLLLFNIHGLRLQTFHYCPEEILRLWVDP
                     LHVIVTCNDGSMDVYAWEERSLLLRKCYRLQNRRNLPPESFIFKTLCDDVSIIGVMTN
                     SPAPCFLMAYTLASALEN"
     exon            143..180
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            181..344
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            345..463
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            464..673
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            674..832
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1043
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1222
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1347
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1511
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1489..1494
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /note="hexamer: AATAAA"
     polyA_site      1510
                     /gene="Fbxw20"
                     /gene_synonym="Fbxw12"
                     /note="major polyA site"
ORIGIN      
        1 gaacaagctt gggaggagaa aggagagtca gtgtggactt aggccacaaa agatggaggt
       61 ccatttgcct agattgccat tgatgaaaat cttctcctat ctggatgcct acagtttgct
      121 acaggctgcc caagtgaaca agaactggaa tgaacttgca agcagtgatg tcctgtggag
      181 gaagttgtgt cagaagagat ggctcttctg tgacatggtt accctacagc tcctgggcac
      241 agagacatgg aagcagttct tcgttttccg aacatggcaa gaacatgcca agacccgggc
      301 aaagccagaa gatttcactt acaaggaaat tcctgcggag tatggatttc gggcaaatgc
      361 atgttatatc tcagggtgtg gcttaacaag aaacgtacaa gacaggtcgg tcatctgtat
      421 ggtgagttcc atgaccaagt tgtccacctg ggatattcgt gagggcatta tgacctgggt
      481 aagcacagaa cagccagcct atatcaagct gttgactacc ctccctgaga tgcacattgc
      541 ggtcactgta gatacacact caactatcaa actgtgggac tgccacaaca gggaagctct
      601 ggcaactaac tgcctgttct cctcctgtaa attactgaaa gctgtgtttt caaaggatga
      661 cccaattgtc ttggtaggcg atatctcggg aaacctctac atctttagga ttcctgactt
      721 acacctcatt tccaaggtga atgtattccc atacggtatt gatgaactcc actgctctcc
      781 tcagaagaaa tgggtctttc tgattatgaa acacccacgt gtcttgacaa aggtcgttta
      841 catgaacagc ttactgagga catcagaatt ctctgcccct gtgtctacca ttctcaaatt
      901 ttcattatgt gataaagcct tctggacccc aagaagggaa gacaggataa cccagatgtc
      961 cagaggtgtc cccccaagac ccacaaaatt tgccacattt gatatgaagc tggaagagat
     1021 tgggaacaaa gtaactgttc aagaatattt ggtcgcaagc ttctctttgc aagattatga
     1081 ggcgagtcca gaatggatgg gagtcagtaa taaggacgtg attgtttgtt caactggatc
     1141 ctctctcttg ctcttcaaca tacatggtct ccgtcttcag acatttcact actgcccaga
     1201 agagatcttg agactatggg tggaccccct tcatgtcatc gtcacctgta acgatggctc
     1261 tatggatgtg tatgcatggg aggagagaag cctgctgctc agaaagtgtt atcggctgca
     1321 aaacaggaga aatctgccac cagaaagctt cattttcaaa accctatgtg acgatgtgag
     1381 cataattgga gtgatgacaa atagtcccgc cccctgcttt ctgatggcat ataccttggc
     1441 atctgctctt gaaaactgag tgagttatgt gtcctcttcc tcaatgataa taaaggtctt
     1501 tttgcaaaga t
//
