LOCUS       NM_001033794            1519 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus F-box and WD-40 domain protein 18 (Fbxw18), mRNA.
ACCESSION   NM_001033794 XM_884363
VERSION     NM_001033794.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1519)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC139081.1 and AK136230.1.
            
            On Feb 5, 2010 this sequence version replaced NM_001033794.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136230.1, AK162167.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 BC139081.1         1-1
            2-1519              AK136230.1         6-1523
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 59.69 cM"
     gene            1..1519
                     /gene="Fbxw18"
                     /note="F-box and WD-40 domain protein 18"
                     /db_xref="GeneID:546161"
                     /db_xref="MGI:MGI:3505704"
     exon            1..150
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1461
                     /gene="Fbxw18"
                     /codon_start=1
                     /product="F-box and WD-40 domain protein 18"
                     /protein_id="NP_001028966.1"
                     /db_xref="CCDS:CCDS40775.1"
                     /db_xref="GeneID:546161"
                     /db_xref="MGI:MGI:3505704"
                     /translation="METHLPSLPSLPMMKILSYLDAYSLLQVAQVNKNWNALASSDVL
                     WRKLCQKRWLYCDTVILQLHDKETWKQFFVNRTYQEHTKTRAKPEDFTYKEICAETGI
                     WAYACYISGRGLTRNGQGTSVVCMLTSMTKISTWDIHEGVMTWVSPVQPTTIKLLNTL
                     PEMHIAVTVDIHSTIKLWDCNSSDALATNNLFFPCQTLKSVFTKDAAIVLVSDTLGNL
                     YIFRIPDLHLISTINVFPYGINELYCSPQKKWVFLSRKHPHILPKVFYMNSLLRRSEF
                     SAPVSTVLNFSLCDKAFWTPRKEDRITLMSISAPYKVTKFVTFDMKLEEIGNQIIVTG
                     YLIASFSLTDYEGRLECFGVSDKDVIVCSTGSSLLLFSIYGVCLQTFDYCSEEILRLW
                     VDPFHVIVTFIDGSLDVYAWEERCQQLSKCYRLQNRRRLPRQSCFEKTLCDEVSIIRM
                     VRNGRNPCYLMTYTLNIHS"
     exon            151..188
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            189..352
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            353..471
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            472..681
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            682..840
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1051
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1230
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1355
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
     exon            1356..1519
                     /gene="Fbxw18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcaagctg gggaggagaa aggagagtag tgtggactta ggccactgaa gatggagacc
       61 catttgccta gtttgcctag tttgcctatg atgaaaatcc tctcctatct ggatgcctac
      121 agtttgctac aggttgccca agtgaacaag aactggaatg cacttgcaag cagtgatgtc
      181 ctgtggagga agttgtgtca gaagagatgg ctctactgtg acacggtcat cctacagctc
      241 catgacaaag agacatggaa gcagttcttt gttaaccgaa catatcaaga acacaccaag
      301 acccgggcaa agccagaaga tttcacctac aaagaaattt gcgcagagac tggaatttgg
      361 gcatatgcat gttatatctc agggcgtggc ttaacaagga atggacaagg gacatcggtt
      421 gtctgtatgt tgacttccat gaccaagatt tccacctggg atattcatga gggtgttatg
      481 acctgggtaa gcccagtaca gccaactact atcaagctgt tgaataccct ccctgagatg
      541 cacattgcag tcactgtaga tattcactca actatcaaac tgtgggactg taatagcagt
      601 gatgctctgg cgactaacaa cctgttcttt ccatgtcaaa cactgaaatc tgtctttacc
      661 aaggatgctg ctattgtctt ggtaagcgat accttgggta acctctacat ctttaggatt
      721 ccagatttac acctcatttc cacaatcaat gtattcccat acggtattaa tgaactctac
      781 tgctctcctc agaagaaatg ggtctttctg agtaggaaac acccacatat cttgccaaag
      841 gtgttttaca tgaacagctt actgaggaga tcagaattct ctgcccctgt gtctaccgtt
      901 ctcaattttt cattatgtga taaagccttc tggaccccaa gaaaggaaga ccggataacc
      961 ctgatgtcca taagtgctcc ctataaagtc acaaagtttg tcacatttga tatgaagctg
     1021 gaagagatcg ggaaccaaat aattgttaca ggatatttga tagccagctt ctcgttgaca
     1081 gactatgagg ggagactgga atgctttgga gtcagtgata aggacgtgat tgtttgttca
     1141 acgggatcct ctctcttgct cttcagcata tatggtgtct gtctgcagac atttgactac
     1201 tgctcagaag agatcttgag actatgggtg gacccctttc atgtcattgt cacttttatc
     1261 gatggctctt tggatgtgta cgcatgggag gagagatgcc agcaactcag taagtgttat
     1321 cggctgcaaa acagaagacg gcttccacgg caaagttgct ttgaaaaaac tttatgtgac
     1381 gaagtgagca taattcggat ggtgagaaat ggtcgcaatc cctgctatct gatgacatat
     1441 accttaaaca ttcactcttg aaatctgagt gggttgtgtg tcctcttcct caatgataat
     1501 aaaggtctat ttgcaagca
//
