LOCUS       NM_175401               1823 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus F-box and WD-40 domain protein 17 (Fbxw17), transcript
            variant 1, mRNA.
ACCESSION   NM_175401
VERSION     NM_175401.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1823)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1823)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK135553.1, BC040428.1 and BX518527.1.
            
            On Mar 1, 2018 this sequence version replaced NM_175401.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC040428.1, SRR5189685.153792.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                AK135553.1         2-14
            14-1798             BC040428.1         1-1785
            1799-1823           BX518527.1         485-509
FEATURES             Location/Qualifiers
     source          1..1823
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 25.72 cM"
     gene            1..1823
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /note="F-box and WD-40 domain protein 17"
                     /db_xref="GeneID:109082"
                     /db_xref="MGI:MGI:1923584"
     exon            1..124
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1435
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /codon_start=1
                     /product="F-box and WD-40 domain protein 17"
                     /protein_id="NP_780610.2"
                     /db_xref="CCDS:CCDS36661.1"
                     /db_xref="GeneID:109082"
                     /db_xref="MGI:MGI:1923584"
                     /translation="MAPQLGPHELQHIFSFLEARDLLRAAQVNKVWNEVSMTKELWRQ
                     LCLRRWASCKAFPVVVGTQTWKKYYFCRSELEFRMESGRPQDFICKAISGHTGMIDQL
                     AYVSPHEYRFDEGARSVVCTVSSDCTVRAWDLQEGSEIWSSAVQPAPLVNVVAYPQLQ
                     LVVTVDIQGLIMGWKAKTGSEWAFFSLPASCSSMEACDHPEGPFLLVACDEGTLYTMT
                     VPQLQVVSRVPTFPHSSVSLTCSPDTQWVFVSAQGSDLGPKVFYTQPLLHPSEDRLPV
                     STTLPIRLSSRACWAPDEAARLMVIHRDDGGVHLVITTFELKATKSRDRLSILAQQLA
                     SFHLPDTMTPHLMQGHGSQTILLTSRSELVLFTIHGLQLMAFQDHQRPITSMWVDPDR
                     VITAALDLSLRVYVWNKKNTSPVLKSCYHLLGGSHRWASGFTHVKSDSRSIAGVEARS
                     TGTSILRSYCFKVKLD"
     exon            125..162
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            163..323
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            324..442
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            443..652
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            653..811
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1022
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1198
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1326
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1810
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1773..1778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1810
                     /gene="Fbxw17"
                     /gene_synonym="1110064L07Rik"
                     /note="major polyA site"
ORIGIN      
        1 agcagacgca cggggctagg gcgtggcaag cgggatggcg ccgcagcttg gcccgcacga
       61 actgcagcac atcttctcct tcctggaggc ccgggacctg ctgcgcgctg cgcaggtgaa
      121 caaggtctgg aatgaggttt cgatgaccaa ggaactgtgg aggcagctgt gtctgaggcg
      181 atgggcctcc tgcaaggcct tcccagtggt cgtgggcacg caaacatgga agaagtacta
      241 tttctgccgg tctgagctag agttccgtat ggaatctggg cggccacagg atttcatctg
      301 caaagctatt tctgggcaca caggaatgat agatcagctg gcctacgtct caccccatga
      361 gtaccgcttt gatgaagggg caaggtccgt ggtttgcact gtgtcttcag actgtactgt
      421 gcgtgcctgg gatctgcagg agggctcaga gatctggtca agtgctgtgc agcctgctcc
      481 tctggtgaat gtggtggcct atcctcagct gcagctggtt gtcactgtgg acatacaggg
      541 cttgatcatg gggtggaaag caaagaccgg gtctgagtgg gccttcttca gcttgccggc
      601 atcctgttct tcaatggagg cctgtgacca cccagagggc cccttcttgc tggtagcctg
      661 tgatgaaggg accctctaca ctatgacagt acctcagctg caagtggtct ccagagtacc
      721 cacatttcct cactcctctg tgagcctcac gtgctcccct gacacacagt gggtatttgt
      781 gtctgcacaa ggctcagact taggcccaaa ggtgttctac actcagccct tgctgcaccc
      841 atcagaagac agacttcctg tctccactac ccttcccatc aggctgagct ccagagcctg
      901 ctgggctccg gatgaggcag ccagactgat ggtgatacac agagatgacg gtggcgtgca
      961 tctggttatc actaccttcg agttaaaggc caccaagtcc agggacagat tgagcatcct
     1021 tgcacagcag ctggccagct tccacctgcc ggacactatg actcctcacc tcatgcaggg
     1081 ccatggctcc caaacgatcc tgctcacctc caggtcagag ctggtgctct tcaccataca
     1141 tggcctgcag ctgatggcct tccaggacca ccagaggcca atcacgtcta tgtgggtgga
     1201 tccagaccgt gtcatcactg ctgccttgga cctgtccttg cgtgtctatg tgtggaataa
     1261 aaagaacaca tcacctgtcc tcaagagctg ttaccatttg ctcgggggat ctcacagatg
     1321 ggccagtgga ttcacccacg tgaagagtga cagcagaagc attgctgggg tggaagccag
     1381 aagcactggg acaagtattc tgaggtcata ttgcttcaag gttaagcttg actagacgcc
     1441 accagttgaa gatgctctgg cttggtgtgc gtgcaaagtc cttaccaaag atgttgtcaa
     1501 ctttggaaaa aaaactagca agatgcctgc ttcctaacaa aatgcctgct gccttctcac
     1561 agagagccga tgaagtggtt tctgtcatct tacatttcac tgtcctgctc aaacaaggga
     1621 gaataagtcc cctcttcagg cgctttccca ggtggcacgg tttcccaggt ggtcacagac
     1681 agagtggact gtttgtggta gtgctgaatt tatagcctgc tcgtttgcag tgtccagatg
     1741 gcaacagagt tgtttttgtt accaagaatg taattaaaat atttttattt gcctgtgctg
     1801 tagagacaca aaaaaaaaaa aaa
//
