LOCUS       NM_025995               1820 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus F-box protein 5 (Fbxo5), mRNA.
ACCESSION   NM_025995
VERSION     NM_025995.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Li,L., Sun,Y., Davis,A.E., Shah,S.H., Hamed,L.K., Wu,M.R.,
            Lin,C.H., Ding,J.B. and Wang,S.
  TITLE     Mettl14-mediated m6A modification ensures the cell-cycle
            progression of late-born retinal progenitor cells
  JOURNAL   Cell Rep 42 (6), 112596 (2023)
   PUBMED   37269288
REFERENCE   2  (bases 1 to 1820)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1820)
  AUTHORS   Naiman,N., Fujioka,K., Fujino,M., Valerius,M.T., Potter,S.S.,
            McMahon,A.P. and Kobayashi,A.
  TITLE     Repression of Interstitial Identity in Nephron Progenitor Cells by
            Pax2 Establishes the Nephron-Interstitium Boundary during Kidney
            Development
  JOURNAL   Dev Cell 41 (4), 349-365 (2017)
   PUBMED   28535371
REFERENCE   4  (bases 1 to 1820)
  AUTHORS   Ray,J.P., Staron,M.M., Shyer,J.A., Ho,P.C., Marshall,H.D.,
            Gray,S.M., Laidlaw,B.J., Araki,K., Ahmed,R., Kaech,S.M. and
            Craft,J.
  TITLE     The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling,
            Differentiation, and Metabolism of T Helper 1 and Follicular B
            Helper T Cells
  JOURNAL   Immunity 43 (4), 690-702 (2015)
   PUBMED   26410627
REFERENCE   5  (bases 1 to 1820)
  AUTHORS   Marangos,P., Verschuren,E.W., Chen,R., Jackson,P.K. and Carroll,J.
  TITLE     Prophase I arrest and progression to metaphase I in mouse oocytes
            are controlled by Emi1-dependent regulation of APC(Cdh1)
  JOURNAL   J Cell Biol 176 (1), 65-75 (2007)
   PUBMED   17190794
REFERENCE   6  (bases 1 to 1820)
  AUTHORS   Shoji,S., Yoshida,N., Amanai,M., Ohgishi,M., Fukui,T., Fujimoto,S.,
            Nakano,Y., Kajikawa,E. and Perry,A.C.
  TITLE     Mammalian Emi2 mediates cytostatic arrest and transduces the signal
            for meiotic exit via Cdc20
  JOURNAL   EMBO J 25 (4), 834-845 (2006)
   PUBMED   16456547
REFERENCE   7  (bases 1 to 1820)
  AUTHORS   Okada,A., Kushima,K., Aoki,Y., Bialer,M. and Fujiwara,M.
  TITLE     Identification of early-responsive genes correlated to valproic
            acid-induced neural tube defects in mice
  JOURNAL   Birth Defects Res A Clin Mol Teratol 73 (4), 229-238 (2005)
   PUBMED   15799026
REFERENCE   8  (bases 1 to 1820)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 1820)
  AUTHORS   Paronetto,M.P., Giorda,E., Carsetti,R., Rossi,P., Geremia,R. and
            Sette,C.
  TITLE     Functional interaction between p90Rsk2 and Emi1 contributes to the
            metaphase arrest of mouse oocytes
  JOURNAL   EMBO J 23 (23), 4649-4659 (2004)
   PUBMED   15526037
REFERENCE   10 (bases 1 to 1820)
  AUTHORS   Reimann,J.D., Freed,E., Hsu,J.Y., Kramer,E.R., Peters,J.M. and
            Jackson,P.K.
  TITLE     Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits
            the anaphase promoting complex
  JOURNAL   Cell 105 (5), 645-655 (2001)
   PUBMED   11389834
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159325.13 and BC053434.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_025995.3.
            
            On Jul 7, 2006 this sequence version replaced NM_025995.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053434.1, AK160201.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-76                AC159325.13        169884-169959
            77-1438             BC053434.1         1-1362
            1439-1820           BC053434.1         1364-1745
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 1.91 cM"
     gene            1..1820
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /note="F-box protein 5"
                     /db_xref="GeneID:67141"
                     /db_xref="MGI:MGI:1914391"
     exon            1..207
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1394
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /note="early mitotic inhibitor 1; f-box only protein 31"
                     /codon_start=1
                     /product="F-box only protein 5"
                     /protein_id="NP_080271.2"
                     /db_xref="CCDS:CCDS56683.1"
                     /db_xref="GeneID:67141"
                     /db_xref="MGI:MGI:1914391"
                     /translation="MSRRTCSDLRRPSSCPCRLGARTTVDGCKEESPVLSVTMKCFNC
                     NPDLSELEVVKPEDSGIEASYSPVCLEPSCNDCVRNHERLSFIDSPIVGHDNKENQRV
                     QNTLDSSNETEELEASRLYEDSGYSSFTQSDRDDGILILENFRNSPQARLLPSQSPDQ
                     HPNKTLLPVLHFERVVCSTLKKNGKRNPKVDREMLKEVIASGNFRLQNIIGKKMGLEH
                     LDILAELSRRGFVHLLANILTKLSGMDLVNLSKVSRIWKKILENNKGAFQLYSKTMQR
                     VIESSKLSLHATTRGYVVGRAALTCVQKSSTWAPPKKDVQIKSSSQRGQRVSTYSRHN
                     EFVEVAKTLKNNESLKACVRCNFPAKYDHYLERAVCKRESCQFEYCTKCLCAYHNNKD
                     CLNGKILKASCKVGPLPGTKKSKKNLQRL"
     exon            208..871
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /inference="alignment:Splign:2.1.0"
     exon            872..962
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1142
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1807
                     /gene="Fbxo5"
                     /gene_synonym="2510044I10Rik; Emi1; Fbxo31"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaattcaaag attttaaaag taccagctgg cgccttttaa gagctgcggc tcggcgcctc
       61 gtctggccgg ccaccttttt cctgtcgtcg ccgccacctc cccagcattg gagcccgagt
      121 tttgcggcat gagccggcgc acctgcagtg acctgcgccg gccgtcctcc tgtccctgcc
      181 gtcttggcgc gcggactacc gtggacggtt gtaaagaaga aagccctgtt ctttctgtta
      241 caatgaagtg ttttaattgc aaccctgatc tttccgagct tgaagtggtg aagcctgagg
      301 acagtgggat agaagcttcc tacagtcccg tgtgtttgga accttcctgt aatgactgtg
      361 ttagaaacca tgagaggttg tctttcatcg actcaccaat tgtgggacat gataacaagg
      421 aaaatcaacg cgtacaaaac acactagata gttcaaacga aacagaagag ctagaggcca
      481 gtagactgta tgaggacagt ggctactcat ctttcacaca aagtgaccgt gacgatggca
      541 tccttatcct ggagaatttc agaaacagtc cccaggcccg tctgctgcca tcacagagcc
      601 cggaccagca tcccaacaaa accttgctgc ctgtcctgca ttttgaaaga gtggtttgct
      661 caacactaaa aaagaatggc aagcgaaacc ctaaagtgga tcgagaaatg ctgaaggaag
      721 ttattgccag cgggaacttt agactgcaaa atataattgg caagaaaatg ggcctggagc
      781 acctagacat cctggctgag ctctcccgca ggggattcgt gcacctgttg gctaacattt
      841 tgactaagct cagcggcatg gacttagtaa atctgtctaa agtgagcaga atttggaaga
      901 agatactgga aaacaataag ggggcgttcc agctctacag caaaaccatg cagcgagtca
      961 ttgaaagcag taagttgtca ctacatgcta caacgagagg atatgttgtg ggcagagctg
     1021 cactaacttg tgttcaaaag tcatcgacct gggcacctcc caaaaaagat gttcaaatca
     1081 agtcctccag tcagcgtggt cagagagttt ctacctacag ccggcacaat gagttcgtgg
     1141 aggtggcaaa gacattgaag aacaacgaaa gcctcaaagc ctgtgttcgc tgtaatttcc
     1201 ctgcaaaata tgaccactat ttagagcgag cagtctgcaa acgggaaagc tgtcaatttg
     1261 aatattgtac aaagtgtctg tgtgcttacc ataacaacaa agactgtttg aatggcaaga
     1321 tcctaaaagc cagctgtaaa gtgggtcctt tgcctggaac taaaaagagt aaaaagaact
     1381 tacaaagatt gtgatagatc aactgtagat cttggctact ttaaaaagaa aaaaaaaact
     1441 tcaactttaa tttaagaaag taaaaataat tatgatgcct tttgtgaata gagaaattaa
     1501 ttgtccataa aaatgccaag attgacttat gaaaaacaaa ctggatatct atcttagata
     1561 ctaagataaa attgagtgga cttttggcaa gggagggttg tggtcttttt atggagtctt
     1621 gagaacattt gcttcagtat tcgagattcg ctttaccaag tttgtatcat acttctatca
     1681 acttgagtct gtccatttaa atgtttgtca atgtgagttt tttttatatc tgtgaatacc
     1741 tgttttcaaa tgccaaataa aataatacac ataattttgt ttagttaaaa taaatttaga
     1801 ggtgtaaaaa aaaaaaaaaa
//
