LOCUS       NM_175530               2962 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus F-box protein 46 (Fbxo46), mRNA.
ACCESSION   NM_175530
VERSION     NM_175530.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2962)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   2  (bases 1 to 2962)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC145199.3.
            
            On Jul 30, 2009 this sequence version replaced NM_175530.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030147.1, BC049813.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                AC145199.3         89926-90003         c
            79-2962             AC145199.3         71601-74484         c
FEATURES             Location/Qualifiers
     source          1..2962
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.46 cM"
     gene            1..2962
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /note="F-box protein 46"
                     /db_xref="GeneID:243867"
                     /db_xref="MGI:MGI:2444918"
     exon            1..78
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /inference="alignment:Splign:2.1.0"
     exon            79..2962
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..1970
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /codon_start=1
                     /product="F-box only protein 46"
                     /protein_id="NP_780739.1"
                     /db_xref="CCDS:CCDS20890.1"
                     /db_xref="GeneID:243867"
                     /db_xref="MGI:MGI:2444918"
                     /translation="MDRGSLLPFQLWCPRPFSKYSQNQPRPPSTALKPPVCPDTSSGT
                     EPDHRPAHLESTPPAVAAEAPTSQPAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVA
                     FFVAHQCGGSSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGREGTPATEVTP
                     TSSGDDVDLVSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSADQGGPAKGLGSERR
                     SGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPHSPDG
                     NLPNGGGGRPGCAYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEAS
                     EGETPAPTRPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDACIFFGKDGTKNVKEET
                     VCLTVSPEEPPPPGQLFFLQSRGPEGPPEPPPADIPSTVPGPDDSEGTTDTSLCRLYR
                     HVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIE
                     AFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCC
                     RRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR"
     regulatory      2932..2937
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /note="hexamer: TATAAA"
     polyA_site      2956
                     /gene="Fbxo46"
                     /gene_synonym="20D7-FC4; 4932704E22Rik; Fbxo34l"
                     /note="major polyA site"
ORIGIN      
        1 agaacccgga aggggaggct ggagaggagc gagtggggga aacccgcgta gtcgggagag
       61 ctgcagcgcg gggagatggt ggcctggaga gctccccact accatcctgg ccctgaggct
      121 gagtgactac ctgctgctgc ttgtcattgc tgcccagcat ggacaggggc agcctcctgc
      181 ccttccaact ctggtgcccc cggcccttca gcaagtattc ccagaaccag ccgcgcccac
      241 cttccacagc cctcaagccg ccagtctgtc ctgacacaag cagcgggact gagcccgacc
      301 acaggcctgc gcacttggag agcacaccac ctgccgtggc tgcagaagcc cccacctccc
      361 agcctgctcc actcctctct acagcagctt ccggtgatga aggtcgggtc ctgctggaca
      421 cgtggtatgt tatcaagcct ggaaatacaa aggagaaggt ggccttcttt gtggcccacc
      481 agtgtggtgg aagtagccgg gccagctcta tgaaggtcaa agggcactgg ggcagtgaca
      541 gctccaaagc taagaggagg aggcgctgcc ttgagcccac caaggctcct ccagaccaag
      601 ggggccgaga aggaacccct gccactgagg tgacccccac atcatctggg gatgatgtag
      661 acctggtctc tgtagcagaa atggtggccc tggttgaaca gagagctgcc ctggccctgc
      721 agagttatcc gcgccccagt accccagctc ccgtggtctt tgtgtcagct gatcaggggg
      781 gaccagccaa ggggctaggg tcggaaaggc ggtctggtgg tggtgactgc agccgagttg
      841 ctgaggcagt ggcccacttt gaggcccagc gggacagccc tcctaccaag ggtctccgca
      901 aggaggaacg gccaggccct gggcccggcg aggtgcgtat agctttccga atctccaatg
      961 tccgagagcc ccattcacca gatggcaact tacccaatgg gggtggaggc cggcctggtt
     1021 gtgcctaccc tggtagtcct ggacctggga ctcgagccaa agacaaaatc acctgcgact
     1081 tgtaccagct tatcagcccc tccagggatg cccttcccag caatgtggag ttcctattgg
     1141 ccagggctga tgaagccagt gagggtgaga caccagcccc caccaggcct gaggacactc
     1201 caccagcacc gcctccaccc cctgcccggg actgtggtgc atcaggattc catgtagatg
     1261 tggtggtaac aggtgtagtg gatgcgtgca tcttctttgg caaagatggc accaagaacg
     1321 tgaaggaaga gactgtgtgc ctgacagtga gccctgagga gccaccccca cctggccagc
     1381 tcttcttctt gcagtcccgt ggtccagaag ggcctcctga gccaccccca gctgatatac
     1441 caagcacagt gccaggcccc gatgattctg agggcacaac ggacacctcc ctctgccgcc
     1501 tgtaccggca tgtgtcacac gacttcctgg agattcgctt taaaatccag cgtcttctgg
     1561 agccacggca gtacatgctg ctgctgcctg agcacgtgct cgtcaagata ttcagcttcc
     1621 tgcccacgcg ggccttggca gccctcaagt gcacctgcca ccacttcaag gggatcatcg
     1681 aggctttcgg tgtgcgtgcc acggactctc gctggagccg ggacccgctc taccgagacg
     1741 acccttgtaa gcagtgccgc aagagatacg agaagggtga tgtgtcactc tgccgctggc
     1801 accccaaacc ctaccaccat gacctgcctt acggacgttc ctactggatg tgctgccgca
     1861 gagccgatcg tgagacacca ggctgtcgcc tgggcttgca tgacaacaac tgggtactgc
     1921 cgtgcaatgg agtgggtgga ggccgtgctg gccgggaaga ggggaggtga agcccgtgga
     1981 tgaggggaca cctgcgatac ctagcccctc cccgctttgc cgggagctgg ggaccaggac
     2041 tgagtcacca gccgacacct accagtccat gcggcagcat ccatctccca ccagaactgg
     2101 gaccaggttt ggggatcaac agggcaaata ccttgcttga cctctgttgg ttttttattc
     2161 ttcagagcca gggccatgga ccctcagaga ggggtgtggt tttttgcttt tttttttttt
     2221 tttttttttt aaatcagcat ctcaatttca cctccatcga gtctctccac cccagggacc
     2281 caccagcagg gggcagacgg cagctaattt tggtaccacc tgaggctttc ctcaagctgg
     2341 cccttcgttc tgtgcctccc ccagttgtct ttggagctgt gcttaccaag gcgctgcatg
     2401 ctctgagggt ggctcatcca ggcccttagc tcacaactca agtcggcact tttttgaggc
     2461 agcccagcat ttctagatgt ttcctcatta aataaaaaaa aagttttctt ctgaacctca
     2521 aactaccaga gtctctaggg aaaggagggt tgaagtcccc tcaagcgtag gagaacccct
     2581 taggctcttg tcactgactc tttcctcagt aaagctgtga agccccttgc ctcactcctg
     2641 gatgacaagc aagccagagg gacaggccag tgggtctgaa tttcgccagg attcttcttc
     2701 cactttgggg tcctctctga ggcattaggg tctctgcaac taccccaccc cagccacaag
     2761 tttctttaga atctcttggt taactgggac cttaattttg aggcagtttg gtccaaaata
     2821 tttttgtttg gggtttttcc tcgtttgggg gtttcatttt cttttctcct tcattgtggc
     2881 tccgggagcg tctcgtgtgt ggcgtctgac caattttgaa ttggtcgttt ctataaaatc
     2941 aatatttata acgctgtgcc ca
//
