LOCUS       NM_175127               4932 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus F-box protein 28 (Fbxo28), mRNA.
ACCESSION   NM_175127
VERSION     NM_175127.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4932)
  AUTHORS   Zou,C., Synan,M.J., Li,J., Xiong,S., Manni,M.L., Liu,Y., Chen,B.B.,
            Zhao,Y., Shiva,S., Tyurina,Y.Y., Jiang,J., Lee,J.S., Das,S.,
            Ray,A., Ray,P., Kagan,V.E. and Mallampalli,R.K.
  TITLE     LPS impairs oxygen utilization in epithelia by triggering
            degradation of the mitochondrial enzyme Alcat1
  JOURNAL   J Cell Sci 129 (1), 51-64 (2016)
   PUBMED   26604221
REFERENCE   3  (bases 1 to 4932)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   4  (bases 1 to 4932)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   5  (bases 1 to 4932)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC094542.1.
            
            On May 15, 2005 this sequence version replaced NM_175127.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094542.1, AK162188.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 84.93 cM"
     gene            1..4932
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="F-box protein 28"
                     /db_xref="GeneID:67948"
                     /db_xref="MGI:MGI:1261890"
     exon            1..284
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1124
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /codon_start=1
                     /product="F-box only protein 28"
                     /protein_id="NP_780336.1"
                     /db_xref="CCDS:CCDS15588.1"
                     /db_xref="GeneID:67948"
                     /db_xref="MGI:MGI:1261890"
                     /translation="MAAASEERMAEEGGGGHGDGGSCSAAGSAQRQPPAPPSQAPPPG
                     SQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRML
                     NQGFLKVERFHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKY
                     VDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPI
                     LKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVRTNGAGVT
                     VLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGT
                     SSGSGQSEESPRKRRKATEAIDSLRKSKRLRNRK"
     exon            285..394
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /inference="alignment:Splign:2.1.0"
     exon            395..533
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /inference="alignment:Splign:2.1.0"
     exon            534..729
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /inference="alignment:Splign:2.1.0"
     exon            730..4913
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2424..2429
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="hexamer: ACTAAA"
     polyA_site      2452
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="major polyA site"
     regulatory      2808..2813
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="hexamer: AATAAA"
     polyA_site      2827
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
     regulatory      3905..3910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="hexamer: AATAAA"
     polyA_site      3925
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
     regulatory      4892..4897
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
                     /note="hexamer: AATAAA"
     polyA_site      4913
                     /gene="Fbxo28"
                     /gene_synonym="4833428J17Rik; 5730505P19Rik; D1Ertd578e;
                     Fbx28; mKIAA0483"
ORIGIN      
        1 ggaatcaaac tcccaagatg gcggcggcgt ctgaggagcg gatggctgag gaaggaggcg
       61 gcggccacgg cgacggcggc tcctgttcgg ctgccggctc cgctcagcga cagcccccgg
      121 cgcccccgtc gcaggccccg ccgcccgggt cccaggcacc cgccgcgccc gcgctggcac
      181 cggaccacct gccccaaaac aacacactgg tggcgctgcc catcgtagcc atcgagaaca
      241 tcctcagctt tatgtcctac gacgaaatta gccagctccg cctggtttgt aagagaatgg
      301 acctggtctg tcagagaatg ttgaatcagg ggtttctgaa agtggagagg ttccataacc
      361 tgtgtcagaa gcaagttaaa gcacagctac cgaggagaga gtcagaaaga agaaaccatt
      421 ctttagctcg tcatgcagac atccttgccg ctgtggaaac gaggttgtca ctgttgaata
      481 tgaccttcat gaagtatgtg gattccaacc tctgttgctt catcccagga aaggtgattg
      541 atgagattta ccgtgtactg agatatgtca attctaccag agcccctcag cgagctcacg
      601 aggtgctgca ggagttacgg gatatctcct ccatggcgat ggagtacttt gatgagaaga
      661 ttgttccaat tttgaagagg aaattgccag gatcagatgt gtcaggaaga ctcatgggct
      721 ctcctccagt tcccgggcca tccgcagccc tgacaacaat gcagctcttc tccaagcaaa
      781 acccgtccag acaagaggtt accaaactgc agcagcaggt cagaaccaac ggcgctggcg
      841 tgactgtcct caggcgtgag atttctgagc ttcgcaccaa agtgcaagag cagcagaaac
      901 agcttcaaga ccaagaccag aaactgctcg agcagaccca gatcataggc gaacagaacg
      961 cacggctggc agagctggaa cgcaagctcc gggaagtcat ggaaagtgca gtagggacct
     1021 cctcagggtc tgggcagagt gaggagtccc ctcggaaacg acggaaggca acggaagcca
     1081 tagactctct taggaaatcc aaacgacttc ggaataggaa gtagattgga atatggctct
     1141 agctccagag gacgacgtcc gtggctgaga gtttaagcag ttactcctgt caggatatcg
     1201 gagcaacatg gtgtccttag gcttccaggc gatcagacac aacttatact tggctcttgt
     1261 ggttggcatc ctttgcgctt ctctggtgga gctgatgcac agacccgtct taccttgcaa
     1321 tagatttgta ctaaccatgc ccattctatc gtgtttgggg gctaaccttg ctcctgtgca
     1381 ggcgatgtgt taaggttatt tgtttctgca tatatgcaca ttacatacgg attttaaaca
     1441 aacccattct tgacagacta aaagttaagt ttaatacata aaatgtcctg ttcacttgaa
     1501 agaaaaaaaa aatctacttt ttaaatggac actatcttgt tttttgtttt ttgttttttt
     1561 taaaaagttg actttttgtt tgttataagt gacctttgtc tggaatgtct gagacacggt
     1621 tagtactttg gtattgaagt gatgggtgac agaaggactg agagtattgg ctgtagaggg
     1681 ggctctacag tagcaactat ttttataaac tactggcaag gggtgtctcc aggcgttagg
     1741 tacatgcttt cagttttctt tggggccgtg tcctccattt gcatggatgg atgcatgcat
     1801 tgcctaggca gcgcacttca taccactcct gcactggtgt tgatcttgaa cctctagact
     1861 tctccactgt tagagctgcg ccgacattga tttaagcact cagcagctta cctgtcggga
     1921 gagagttgtc agtccatttg tcctccagtt ttacaggcac aagagactgt tagagtccat
     1981 tgatgtatct cttctctgta gggttcaggt gtactggcta agacagaacc tcaaatccaa
     2041 ggctctttct ttctatagac atcagacctc tgatctgact cagctctgtg ctcctgggtc
     2101 aaccatgact tagtagggac ccaactgagg gaaagtttgt tgaagaaaat tatatcatga
     2161 aaaaaacatt tcatttctgg ggcatgacct gagggaagct ttttcatacc actttcaagc
     2221 tctcacataa ataactctga acagagcttt agtcttgttt gcactcctgt tttgagcttg
     2281 taactggaaa agcctgtctt gcgctgtcag cctcctgaat ggtcacttta acaacctcca
     2341 aattgtataa aatggttctt tctcccggtt gtatattttt gaaacattca actatcactg
     2401 tcgtattttt attttaatta tgtactaaat tatgtagttt tgttctttta aacatctgtt
     2461 gctttggact ttgtttattt atagtaaatg taggtgtaag atggtaaaaa ctatcccttt
     2521 caggtgaaag ttgacccctg tgttacctga gggtttggta accccacagt gggagaaaag
     2581 cacaaggttg tcatccgtcc agcgtgacac attatgcatc ctttaggtta cttttaccaa
     2641 gtgacactct cctacgcact cttaagtgtt gtcccttcgt gatcctgccc ttgggttctg
     2701 ttcaaatctc tgactttgaa agtccatcta caatgtagta tgtcttcagt gagaaacctt
     2761 agcatggtat ccaagtgttt catgatttgt tgggaaggta attttaaaat aaacagtttc
     2821 cttaaaagat ttgtcagcaa ggtcatccat aaaggtccct gtctggatct tcttttctca
     2881 gcaggtctct tgcaatccta gaatgtagcc atatcaccgt agccttggag gagggccact
     2941 gagcgcttaa gactccgaag cagcagcata caggatttca aaggagaatc cttatgcatc
     3001 aaagaaaata agcctcaaat tatttcttca ataattatta aaaatttctc aaactatatc
     3061 cagctagcct aaatgtagcc tctagtcttc catgagctag tctgataaag tggcttttct
     3121 gagcacttac acagtaagca ggaaggggtc tacagtgcga gcctgtgatc tccagcccat
     3181 cagacagagc tgtactgttt catgactata accttgagaa taaagctatg actcgcttgc
     3241 cttaagcttc cctcagagta gctgacatgc taggaggttg tcttcgccat ttattaagac
     3301 agctattggg ggtctgtaat gttcactttg ggagaccata gtggtatatg gagtctccaa
     3361 atcatgcact attttaatag ctaaaactgg cttgccctag gaaaacttaa ccagccacct
     3421 gggagagaac gcttgcattt cctggcagga tcttcctttg tttgcatcaa accattccca
     3481 tgcctaagtt tgcccacagt ccacaccaca cacaggcggc atacacacat gaaaagaatg
     3541 gacaggaggg gaggagaaca ggccctgtca ggccgagccc tgcttcgctc cccagacact
     3601 ttgctcacat ggttcccagc catcatgggt tacagaggct ccaaactccc cttgtgatgt
     3661 agagagagcc tggaggcaag ggggccatta actcctgttg tgaagactat ttgggtgccc
     3721 catgtcgaaa gccactggtc caagttgaca ttttttttgg taaaacatga tttttggagt
     3781 actgaactca caggggcttg ccttaattca gtagtttcaa gatgtatgcg ctatattcta
     3841 tgtgttaaaa tggtaaaata ttctatgtag ccccaagagt gggtaaaaca gagtttaatg
     3901 cctaaataaa taagctaaaa aggtgtcaca acagctggat tttttagaga aaatggacat
     3961 ataaaaaata ggctatgcgt catgaacaga aactatggca ccttgggatc gcactactgc
     4021 atgcactgtt ttgtatgcca tttcatagcc tgcactttaa cctccaaaga aatgctgcgt
     4081 ggtgcctgtc ccctgtcagt gagcttatcc cggagtcggc gcttctattt cactctgctg
     4141 agttagtctc ctagctggca ttcttatttg ggttctctgc ttccttagcc ataatacttt
     4201 ctaggatctg agaactcctg tctcgtctat ttccaacagt gtcaaatcct aatttaatgt
     4261 agattcatcc ttgccgatcc acacagtcat agatcctctt ctagtgtgaa tacttgttcg
     4321 ttgcctgtac caaaccctca gaaagcagac actgtaagat ctgaaggtgg gaataaaagg
     4381 cctgaaaggg gaacacacaa agcgatgccc ctgctggaga atggtggagt ctaacaggag
     4441 gctgagcttc ctgctgaatg cttgagatct gcatgaggtc cttcggggca gaagaggttc
     4501 cattataact aacttaaatg tagagcccgt cctcgggaaa ttatcaacaa aacactaagt
     4561 ccacaaaagc cagtggctgc tactggtgga aggtggccac ttcctgctct cactttgagc
     4621 agccgtcctt cactcaaatc gaaactaagg cacgcttgag tgaggttggc ctttcccaat
     4681 ttcccaagaa tccttgttaa atttttaaag ctcaagcatt aaattcacct tcttcccatt
     4741 gtgtcagaag atagccacga gctttagaag cctgggaatc aggtcaggct attgccaaag
     4801 tctagtggtt cgtgctgcca aaaggttaga catgttttaa aaactccttt atgtggtacc
     4861 attgtctgtt tacttaatgc tcatgagcaa caataaacca ctagtttacc gtcaaaaaaa
     4921 aaaaaaaaaa aa
//
