LOCUS       NM_001163702            1966 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus F-box protein 27 (Fbxo27), transcript variant 1, mRNA.
ACCESSION   NM_001163702
VERSION     NM_001163702.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1966)
  AUTHORS   Liu,D., Xing,R., Zhang,Q., Tian,X., Qi,Y., Song,H., Liu,Y., Yu,H.,
            Zhang,X., Jing,Q., Yan,C. and Han,Y.
  TITLE     The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by
            promoting autophagy in cardiomyocytes
  JOURNAL   Exp Mol Med 55 (9), 2025-2038 (2023)
   PUBMED   37658156
  REMARK    GeneRIF: The CREG1-FBXO27-LAMP2 axis alleviates diabetic
            cardiomyopathy by promoting autophagy in cardiomyocytes.
REFERENCE   2  (bases 1 to 1966)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158463.1 and BQ033399.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC075656.1, AK158463.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1948              AK158463.1         2-1949
            1949-1966           BQ033399.1         1-18                c
FEATURES             Location/Qualifiers
     source          1..1966
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.89 cM"
     gene            1..1966
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /note="F-box protein 27"
                     /db_xref="GeneID:233040"
                     /db_xref="MGI:MGI:2685007"
     exon            1..507
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /inference="alignment:Splign:2.1.0"
     exon            508..619
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /inference="alignment:Splign:2.1.0"
     exon            620..715
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /inference="alignment:Splign:2.1.0"
     exon            716..851
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1951
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1928..1933
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /note="hexamer: AATAAA"
     polyA_site      1951
                     /gene="Fbxo27"
                     /gene_synonym="E130008B10Rik; FBG5; Gm161"
                     /note="major polyA site"
ORIGIN      
        1 agagaggcgg taagggacgt gggagacagt ggatggcttc ggggatgtta gtctcggggt
       61 ggacggctgc aaagcctggc agcagaggct gctaatcact aacatctaac ccctcttctc
      121 ctgcagtccc agccaagcgg ggcgcgggga ccatgggtgc ctggatatcc aggacccggg
      181 tcccgacgcc ggagcccgac ccccaggagg tcctggacct gagccgtctg cccccggagc
      241 tgctcctgct ggtactgagc cacgtgcccc cgcgcacgct gctgatgcac tgccgccgag
      301 tgtgccgcgc ctggcgcgcc ctggtagatg gccaggccct atggttgctg ctgctggccc
      361 gtgaccacag cgcagcgggc cgcgccctgc tgacactagc ccgccgctgt ctgccccctg
      421 cccacgaaga cacgccctgc ccgctgggcc aattctgcgc actgagaccg ctaggacgca
      481 acctcatcag caacccctgt ggccaagaag gcctgcgcaa atggatggtg cggcacggtg
      541 gggatggatg ggtggtggag aagaacagga aacctgtacc tggggcccct tcacagacct
      601 gcttcgtgac ttccttcagc tggtgtcgca agaagcaggt cgtggacctg gtggagaagg
      661 gtctgtggcc agagctgctg gacagtggtg gtgtggagat tgctgtctct gactggtggg
      721 gagctcgaca tgacagtggc tgtaagtacc gtctctttgt cacgcttctt gatgcccacc
      781 agaacgtcat agataagttc tccgctgtgc cagatcccat tgaacagtgg aacaatgata
      841 tctacctgca ggtcacccac gtgttctccg gcatcaggag gggcatacgt tttgtctctt
      901 ttgaacactg gggccaggac acacagttct gggctggcca ctatggggcc agagtgacga
      961 actccagtgt gatcatacga gtctgtcagt cctagtcaaa aggccgccat tttggcaaga
     1021 caatctgaat gtgccttcct ggagctgtcg gctggaatcc ctcatgagtc aagtactgta
     1081 cctccctggc acatgaaact ctgggatcca gtgaagggtc ctgcttggtc ttgttttcag
     1141 agtctgtaac attgaagccc tccatcagat ctacctatta ctgctgcttt agagcatgag
     1201 tgcctaggtg cctggatgca tgtgtgcccg gatgcatgga tgcctgggtt cctagatgca
     1261 tagatgcctg ggtgcctgga tgcatggatg cctgggtgcc cggatgcatg gatgcatggg
     1321 tgcccggatg catgggtgca tgctggtctc aagtcacaag ctgcctctat ttcagttcgc
     1381 tcacctcttt gccctgtccc cagtattgat cccccaccct tttttgagac agggcatccc
     1441 agctggcgac aaccctcctt tctgcctttg acactcatgt gctgggacta caggcacaca
     1501 ccagtaccac tcagtcttgt gcagtgctgg ggatgagccc agggtttcat gcatgccagc
     1561 aaacattcta ctatctgagc aatgtcccca gtgtcccctc tggtcatgtc ctgtttctgc
     1621 ctcagggatt gtctctgttc cttcgctgag gccctctact tagggctgaa cataggattt
     1681 atggctagca gaattccagc tcccttgggt aaggaaccaa agctctcttg gctatagcca
     1741 gcctcctcat tgaagggtgt tttagggtat ctgcccacag attttctcca aacaattggg
     1801 aagtgcctag agtccaggcc ccgatcatca aagatgtcta tattgtataa tatttaaagt
     1861 tatttttaat tttctcaaac aatatgagaa tatctatctg gcattatcta tctgccaatc
     1921 tcactgtaat aaattgatta ttttgcctaa aaaaaaaaaa aaaaaa
//
