LOCUS       NM_027708               2159 bp    mRNA    linear   ROD 08-OCT-2024
DEFINITION  Mus musculus F-box protein 24 (Fbxo24), mRNA.
ACCESSION   NM_027708 XM_132440 XM_916784
VERSION     NM_027708.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2159)
  AUTHORS   Kaneda,Y., Miyata,H., Xu,Z., Shimada,K., Kamoshita,M., Nakagawa,T.,
            Emori,C. and Ikawa,M.
  TITLE     FBXO24 deletion causes abnormal accumulation of membraneless
            electron-dense granules in sperm flagella and male infertility
  JOURNAL   Elife 13, 92794 (2024)
   PUBMED   39163107
  REMARK    GeneRIF: FBXO24 deletion causes abnormal accumulation of
            membraneless electron-dense granules in sperm flagella and male
            infertility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2159)
  AUTHORS   El-Mergawy,R., Chafin,L., Ovando-Ricardez,J.A., Rosas,L., Tsai,M.,
            Rojas,M., Mora,A.L. and Mallampalli,R.K.
  TITLE     FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin
            mediated degradation modulates mitochondrial respiration
  JOURNAL   J Biol Chem 300 (6), 107359 (2024)
   PUBMED   38735474
  REMARK    GeneRIF: FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for
            ubiquitin mediated degradation modulates mitochondrial respiration.
REFERENCE   3  (bases 1 to 2159)
  AUTHORS   Li,Z., Liu,X., Zhang,Y., Li,Y., Zhou,L. and Yuan,S.
  TITLE     FBXO24 modulates mRNA alternative splicing and MIWI degradation and
            is required for normal sperm formation and male fertility
  JOURNAL   Elife 12, 91666 (2024)
   PUBMED   38470475
  REMARK    GeneRIF: FBXO24 modulates mRNA alternative splicing and MIWI
            degradation and is required for normal sperm formation and male
            fertility.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2159)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 2159)
  AUTHORS   Kenney-Hunt,J.P., Vaughn,T.T., Pletscher,L.S., Peripato,A.,
            Routman,E., Cothran,K., Durand,D., Norgard,E., Perel,C. and
            Cheverud,J.M.
  TITLE     Quantitative trait loci for body size components in mice
  JOURNAL   Mamm Genome 17 (6), 526-537 (2006)
   PUBMED   16783635
REFERENCE   6  (bases 1 to 2159)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK016870.1 and AC124730.5.
            
            On or before Jul 23, 2009 this sequence version replaced
            XM_916784.2, XM_132440.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016870.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1393              AK016870.1         2-1394
            1394-1394           AC124730.5         74935-74935         c
            1395-2159           AK016870.1         1396-2160
FEATURES             Location/Qualifiers
     source          1..2159
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.59 cM"
     gene            1..2159
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /note="F-box protein 24"
                     /db_xref="GeneID:71176"
                     /db_xref="MGI:MGI:1918426"
     exon            1..140
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..1907
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /codon_start=1
                     /product="F-box only protein 24"
                     /protein_id="NP_081984.1"
                     /db_xref="CCDS:CCDS51674.1"
                     /db_xref="GeneID:71176"
                     /db_xref="MGI:MGI:1918426"
                     /translation="MVKRSCPSCGLEAGSEKKERGNPISVQLFPPELVEHIVSFLPVK
                     DLVALGQTCHYFHEVCDAEGVWRRICRRLSPRIRDQSSGARPWKRAAILNYTKGLYFQ
                     AFGGRRRCLSKSVAPMLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSSTLGQIQWK
                     RACRYVVLCRGAKDFASDPRCDTVYRKYLYVLATREQPAVVGTTGSRACDCVEVYLQS
                     SGQRVFKMTFHHSMSFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQ
                     LALRKVSRCLPHLRVTCMASNQSSTLYITGGTLIPRKQVPKAAELRAPDPPDQGGVYF
                     EVHTPGVYRDLFGTLQAFDPLDHQMPLALSLPAKVLFCALGYNHLGLVDEFGRIFMQG
                     NNRYGQLGTGDKMDRGEPTQVHYLQRPIALWCGLNHSLVLSQTSDFSKELLGCGCGAG
                     GRLPGWPKGSASFVKLHIKVPLCACSLCSTRECLYMLSSHDIEQCPVYRDLPASRVGG
                     SPEPSQGAGAPQDPGGTAQACEEYLSQIHSCPTLQDRMEKMKEIVGWMPLMAAQKDFF
                     WEALDMLQRAAGGAGPDTSTPES"
     exon            141..236
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            237..420
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            421..659
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            660..894
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1053
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1241
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1373
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1544
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..2159
                     /gene="Fbxo24"
                     /gene_synonym="4933422D21Rik; Fbx24"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatagagggg cccttgaggc cccccaagcc tagactgggg acatggtgtg ggaaaggcag
       61 cggggacggg ggcctggggc ctgggcagcc gaggggcctg gagagatgag ggcaggagca
      121 gggaggggcc agtcaggatg gtgaagcgca gctgcccttc ttgtggcctg gaggctggga
      181 gtgaaaagaa ggaaagaggg aaccctattt ctgttcagtt gttcccccca gagctggtgg
      241 aacacattgt ctccttcctc ccagtcaaag acttggtcgc cctaggccag acctgccact
      301 acttccatga agtgtgtgat gctgagggcg tgtggaggcg catctgtcga aggctcagcc
      361 ctcgaatccg tgaccagagt tctggtgccc ggccctggaa gagagctgcc attcttaact
      421 atacaaaggg cctgtatttc caggcattcg gaggacgccg ccgatgtctc agcaagagtg
      481 tggcccccat gctagcccat ggctaccgcc gcttcttacc cacaaaggac cacgtgttca
      541 ttcttgacta cgtggggacc ctcttcttcc tcaaaaatgc tctggtctcc tccaccctcg
      601 gccagatcca gtggaagcgg gcctgccgct acgtggtgtt gtgtcgaggc gccaaggatt
      661 ttgcgtccga cccaagatgt gacacggttt accggaagta cctctatgtt ttggctactc
      721 gggaacagcc ggcagtggtg ggcaccaccg gtagccgcgc ctgtgactgt gtggaggtct
      781 atctgcagtc cagtgggcag cgggtcttca agatgacatt ccaccactcc atgagcttca
      841 agcagatcgt gctggttggc caggagaccc agcgggccct actgctcctc acagaggaag
      901 gaaagatcta ctccttggtt gtgaatgaga cccagctgga ccagccacgc tcctatacag
      961 tgcagttagc cctcaggaag gtgtctcgat gcctgcctca cctgcgtgtg acctgcatgg
     1021 cttccaacca gagcagtacc ctctatatca cgggtgggac tttaatccct aggaaacagg
     1081 tgcctaaagc tgccgagctg agggctcctg accccccaga ccagggggga gtgtattttg
     1141 aggtgcatac ccccggggtg tatcgtgatc tctttgggac ccttcaagcc tttgaccccc
     1201 tggaccacca gatgccactg gctctctcct tgcctgccaa ggtcctcttc tgtgctcttg
     1261 gctataatca tcttggcctg gtagatgaat ttggccggat ctttatgcag ggaaataaca
     1321 gatacgggca gctgggaact ggagacaaaa tggaccgagg ggagcccaca caggttcact
     1381 atctgcaacg ccccatcgcc ctgtggtgtg gcctcaacca ttccttggtg ctgagtcaga
     1441 cctcggattt cagcaaggag ctgctggggt gcggctgtgg ggccggaggc cgtcttcctg
     1501 gctggcccaa ggggagcgcc tccttcgtca agctgcacat caaggtccct ttgtgtgcct
     1561 gctccctctg ctccaccaga gagtgtctct atatgctgtc cagccacgac atcgaacagt
     1621 gccctgtcta tcgagacctg ccagccagca gggtgggggg gagccctgaa cctagccagg
     1681 gggctggagc cccccaagac cctgggggaa cagcccaggc ctgtgaggag tacctcagcc
     1741 agatccacag ttgccccacg ttgcaggacc gaatggagaa gatgaaggag attgtgggct
     1801 ggatgccctt gatggctgcc cagaaagatt tcttctggga ggcactggac atgttgcaga
     1861 gggctgctgg aggggctggc ccagacacct cgactcccga gagctgaacc cctcttctta
     1921 gcctttcctc ctgaaggaag tcgagccgtg ggctagagct gagaagagat ggagtgtcag
     1981 agaacactgt gtgtacatgg gtggggggtg ggggtggggc tgtggggagc agtgctgcgt
     2041 attcgagggg agaggaggga cctcttttat aaatgtgcag gggcctgccc tggaggagcc
     2101 cctaacctga ctatcatgag cgagaaattt gatggacagt agaataaaag gctaaagcc
//
