LOCUS       NM_015794              17001 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus F-box and leucine-rich repeat protein 17 (Fbxl17),
            mRNA.
ACCESSION   NM_015794 XM_001478436 XM_925135
VERSION     NM_015794.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 17001)
  AUTHORS   Raducu,M., Fung,E., Serres,S., Infante,P., Barberis,A., Fischer,R.,
            Bristow,C., Thezenas,M.L., Finta,C., Christianson,J.C., Buffa,F.M.,
            Kessler,B.M., Sibson,N.R., Di Marcotullio,L., Toftgard,R. and
            D'Angiolella,V.
  TITLE     SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling
            and medulloblastoma development
  JOURNAL   EMBO J 35 (13), 1400-1416 (2016)
   PUBMED   27234298
REFERENCE   2  (bases 1 to 17001)
  AUTHORS   Jin,J., Cardozo,T., Lovering,R.C., Elledge,S.J., Pagano,M. and
            Harper,J.W.
  TITLE     Systematic analysis and nomenclature of mammalian F-box proteins
  JOURNAL   Genes Dev 18 (21), 2573-2580 (2004)
   PUBMED   15520277
REFERENCE   3  (bases 1 to 17001)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 17001)
  AUTHORS   Winston,J.T., Koepp,D.M., Zhu,C., Elledge,S.J. and Harper,J.W.
  TITLE     A family of mammalian F-box proteins
  JOURNAL   Curr Biol 9 (20), 1180-1182 (1999)
   PUBMED   10531037
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ179644.1, CT025670.8, AF176529.1, AC154192.3 and BX515367.1.
            
            On or before Aug 10, 2009 this sequence version replaced
            XM_001478436.1, XM_925135.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.108573.1, AF176529.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-409               CJ179644.1         2-410
            410-1280            CT025670.8         128038-128908       c
            1281-2586           AF176529.1         1-1306
            2587-16610          AC154192.3         188436-202459       c
            16611-17001         BX515367.1         2-392
FEATURES             Location/Qualifiers
     source          1..17001
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 32.68 cM"
     gene            1..17001
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="F-box and leucine-rich repeat protein 17"
                     /db_xref="GeneID:50758"
                     /db_xref="MGI:MGI:1354704"
     exon            1..1556
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     CDS             564..2669
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="F-box only protein 13"
                     /codon_start=1
                     /product="F-box/LRR-repeat protein 17"
                     /protein_id="NP_056609.1"
                     /db_xref="CCDS:CCDS50162.1"
                     /db_xref="GeneID:50758"
                     /db_xref="MGI:MGI:1354704"
                     /translation="MGHLLSKEPRNRPSQKRPRCCSWCRRRRPLLRLPRRALAKASPQ
                     PAAPRSRDCFFRGPCMLCFIVHSPGAPASAGLEEEPPLSPPPPPPRDGAYAAVSSQHL
                     ARRYAALAAEDCAAAARRFLLSSAAAAAAAASSPASCCKELGLAAAAAWEQQGRSLFL
                     AGVGPVRFLGPLAAVQLFRAPPAPPPQAEPATALEMVCKRKGAGVPACTPCKQPRCGC
                     GGCGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASECAPIVAAAG
                     DTVRAGGTAPSSAQQQPESGDADCQEPPENPCDCHREPPPEIPDINQLPPSILLKIFS
                     NLSLNERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNIIEIN
                     ISDCRSLSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDK
                     LTDEGLKQLGSRCRELKDIHFGQCYKISDEGMIVIAKSCLKLQRIYMQENKLVTDQSV
                     KAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCK
                     NLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSVTIETVDV
                     GWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNELTVEQLVQQYPHITFSTVLQDCKR
                     TLERAYQMGWTPNMSAATS"
     exon            1557..1679
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1937
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2069
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2177
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2308
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2385
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2528
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     exon            2529..16991
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3445..3450
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AATAAA"
     polyA_site      3473
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="major polyA site"
     regulatory      8841..8846
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AATAAA"
     polyA_site      8861
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
     regulatory      10554..10559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AATAAA"
     polyA_site      10576
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
     regulatory      11406..11411
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AGTAAA"
     polyA_site      11425
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
     regulatory      16965..16970
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AATAAA"
     regulatory      16970..16975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
                     /note="hexamer: AAGAAA"
     polyA_site      16985
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
     polyA_site      16991
                     /gene="Fbxl17"
                     /gene_synonym="6330576B01Rik; C130023C01Rik; Fbx13;
                     Fbxo13"
ORIGIN      
        1 atccgcttcg ggagaggggc gtgagcccgg aggcgtccag gccacctccg tgtgcagccg
       61 gagggagtgc gcggccccgt cagcgcgcag ccccgaggtc cccgcttctc ccccggcggc
      121 gctcccgccc ctgggtgaga cccgcgcgcc cccgcgggcg gctccgcccc ctcccggagc
      181 gggcggcgcg ctcccgcggc gacgggccgt gtcgcgggct cgcgcgccgc cggcccagcc
      241 gcagttaaaa tggtccgagt cgggcccgcg ctgcccccgc cgcggcgctg actgactgaa
      301 ccggctggcc tggccggcag actcgcttcc ctccctcgcg tccccacagc tcgcgcccgt
      361 cctcctcccg gctccccggg gggcaaagca tgtagcccgc gtcgggcacc cgggcggccc
      421 gcagctgacg cccacccccg ccgtcgcgtg tgccgggtgc gcggcgcggg cgacccagcc
      481 agcggcctgc cccgccgccg gagcccgccc ctcgggcctc cctctcccgc cccgtcccgg
      541 tcgccctcct cggggccttc tatatgggcc accttctctc gaaggagccg cgtaaccgcc
      601 cgagccagaa gaggcctcgc tgctgcagct ggtgtcgccg ccggcgccct ctcctcagac
      661 tgccccgccg ggctctggcc aaggcgtccc cgcagcccgc ggcgccccgg agccgggact
      721 gcttcttccg cgggccctgc atgctctgct tcatcgtgca cagccccggc gcgcccgcct
      781 ccgccggcct agaggaggag ccgccgctct cgccaccgcc gccgccgccg cgggacgggg
      841 cctacgccgc cgtctcctcg cagcacttgg cgcggcgcta cgcggccctg gccgccgagg
      901 actgcgccgc cgccgcacgc cgcttcctgc tgtcctcggc cgccgccgcc gccgccgctg
      961 cctcgtcgcc cgcgtcctgc tgcaaggagc tggggctggc cgccgccgcc gcctgggagc
     1021 agcagggccg gagcctcttc ctggccggcg tggggcccgt gcgcttcctg ggaccgctgg
     1081 ccgccgtgca gctcttccgg gcaccgccgg cgccgccgcc gcaggccgag cccgccacgg
     1141 ccctcgagat ggtttgcaag cggaaagggg ccggggtccc cgcctgcacc ccctgcaagc
     1201 agccccgttg cggctgcggg ggctgcggcg ggggcggcgg cggcggggga gggcccgcgg
     1261 gaggaggtgc ctcgccgccg cggccgcccg atgccggctg ctgccaggcc ccggagcagc
     1321 ccccgccgcc gctctgcccc gcgcccgcct ctcccgcctc agagtgtgcc cccatcgtgg
     1381 ccgccgccgg ggacacagtc cgagccgggg gcaccgcccc ctcgtctgcc cagcagcagc
     1441 ccgagagcgg cgacgcggac tgtcaggagc cccccgaaaa cccctgcgac tgtcacaggg
     1501 agccgccccc cgagatccca gacatcaacc aactgccgcc gtccatcctg cttaagatat
     1561 tttccaattt gtccctgaac gaacgctgcc tttctgcatc gttggtttgc aagtactggc
     1621 gtgacctttg cttagatttc cagttttgga agcagctgga ccttagtagt cgtcagcagg
     1681 ttactgatga attattggaa aaaattgcct ccagaagtca gaatataatt gagattaaca
     1741 tttctgattg tcgaagtctg tctgacagtg gcgtgtgtgt cctagcattt aagtgtcctg
     1801 gacttcttag gtatacagcc tacaggtgta agcagctttc tgacacctca atcattgcgg
     1861 tcgcgtctca ctgcccttta ctgcagaaag tccacgtagg caaccaggac aagctcaccg
     1921 atgaaggact taagcagctg ggctcaagat gcagagaact caaagacatc cattttggcc
     1981 agtgttacaa gatctcagat gaaggcatga ttgtcatagc taagagctgc ctgaagttac
     2041 agaggatata catgcaggaa aacaaattag tgacagatca gtcagtgaag gcatttgctg
     2101 agcactgtcc tgaactccag tatgttggct tcatgggttg ttcagttact tccaaaggag
     2161 tcattcactt aaccaagcta aggaacctgt ccagcttaga cctccgtcac atcactgaac
     2221 tggataatga aaccgtgatg gaaatcgtca agaggtgcaa aaatctcagc tctctgaatc
     2281 tctgtctgaa ctggatcata aacgacaggt gtgtggaggt cattgcaaag gaaggacaga
     2341 acctgaaaga gctgtacctg gtgtcctgta agatcactga ttatgcactg atagccattg
     2401 ggcgatacag cgtgaccata gagactgtgg acgtcggatg gtgtaaagaa atcacagatc
     2461 aaggagccac cctgattgca cagagcagca agtccctgag atacttgggc ctgatgagat
     2521 gtgacaaagt caatgaattg acagtggagc agctggtgca gcagtacccg cacatcacct
     2581 tcagcaccgt tctgcaggac tgcaagagga ccttggagag agcctaccag atgggctgga
     2641 cccccaatat gtccgctgcc acctcctaac tctcttccta tgcccaggtc tactcaggcc
     2701 ggttcagcag aatggagaaa tggggggctc caataggggg tctttcggaa aggttttaac
     2761 cgtcacctgt cagtgtgtgt acccgagtgt tccgtttgtg tcttgtttgc attctgcata
     2821 gcataagcgc actgttactt accccaaggt gagctggctt gttttcccta aaacagaaga
     2881 ttatgaaaac caggaccttt ttgttttttg ttttgttttc caattcaaac gtctatttct
     2941 ctaaaaagac tttgtggaat ctcaagtcag aaaactggtt gtatagtttt gagcttttaa
     3001 gttctgacac atctcggaaa tgctcgcaga aaggctttgt tcggtgatag gtaggctact
     3061 tgtacgcttc tgagaagacc aaaacagaag tgatgttgct ctaactagaa gcctggagac
     3121 tagaacccct caaaatcctg gagtacacag ctaaagttcc actctcttgt actgtcatac
     3181 acacatgcta ggtcaggttc tcgcttggta aattctttcc tgccagagga accttcctgg
     3241 gtcatgaaga gagcatgcct tccactgtgg ctatgcctaa cgtactgtgc ccagtggtgg
     3301 acaacttgct gtcttatagg taacttagga agtagactga ataaagcctt ttgtaaattt
     3361 gtatatggag gcaacagtct gatgtcccct ggccagctca caaaagttaa ttattcatta
     3421 ttctgtaaat gcattctgtt aagtaataaa tattttagtt ggttttgcat taacactgtg
     3481 ttcgctttta ctgtgtggac agttactggt caagatgcat tttagtgaca tttggggcta
     3541 atcttggcat tattcacatt gaagccatga atgtaattaa tggtgtgcag ttattttaaa
     3601 aattttacag atcatttcat tattttggta attatgaaaa tatattctga ggtggggtag
     3661 ttattgatag aagattaatg aatgagatgt atgtagacaa tcttcctatt gtattttttt
     3721 cctttgcttt gggattgaga acaggttttt tgaatatatg catgttataa ttttaaatag
     3781 ttcttacact actgcaaaga tctactgtta gctaacgtat gagctaagga gagaatttag
     3841 aaaatctgtt cattaagatt ctgtttacac ttgccagaaa tacatatttt agtttaatta
     3901 agtattacca gcttttactt ctgtcagtac ctatcaggaa aggagtgtaa gttttgatgt
     3961 cacacatttc tacagtcagc cgttgcaggg actcaggctc agatgacctc tcctatgtct
     4021 ggatttataa gcaggcagca gggagccttt ttaagctaaa gagtgattat ctttcgtagt
     4081 aggaaaagca aaaccttgac ttttgaactt gctatttatt ctccctgtat gtggtctttg
     4141 gtctttaaca attataatga ggtttgagtt tgtttcctat aaatcccagc cctgcggaag
     4201 caatgctagc tgtaggaggc agaagctgcc ttccatttgc acaccatgca cgtgtgtgta
     4261 acaactcctt ctctgtagaa aaggtttgtt tccctccagt ttgtcaacat gcttctgatg
     4321 tggcagttta ttgttttaat cccaatcagt taaaaaacaa aaagtacctt tttcataacc
     4381 aaataggaga ttttatgtga catatgtatt attacatcat taccatagga accaaagtct
     4441 agtcccatgg atgttatttc ctcttccatt ttaattgagt catgaacatg taccaaaacc
     4501 agctggcaat atgacagtca ttgcgactga agggtcagtt ggagtcaggc ctactatgac
     4561 tatcggtaaa taggaggttt ttcctcttgg gcactatgct tagaagatta actcagctct
     4621 cctgcgggat gtttaataca cgcattgccg ctacatggga ctcttcagtc accaaaacgc
     4681 agccatctgc aggaacatat tcccaaacta aaaccatatc taagatcctt cagcgcccag
     4741 tcctgtgatc tcccttggct aataacgaac tgtaaggatg ccagcagctc atgaagaaag
     4801 ggagacttcc aaaagagcct gcgttgtttg attcagctgt tttattcaca acaggatgga
     4861 agagacagtc atgcatttct gaaagttttt ccacagtttg gcatcacttg aaagatctgg
     4921 agatgagaag cattgatgga aagtggcccg aggacacagg gcaggctgat gctcgctcac
     4981 taactcttct gtagcctgag atctcctcag cctgtgcctt gtgcatgcat gcgcgcccac
     5041 atgcccaaat gcaccattca gccagaaaag atgactacag aacgcagtct gttcaacttt
     5101 gtgattaata taatagaaga tggaaaaacg agtcactaaa taaagacttg ttaaacctaa
     5161 cagtctcaca aatagatgct gcccaagtaa gtctgcgtgg ctccagacaa tggtgatttt
     5221 tttttaaaaa aggaagacat tataccaaat gaatgtagac tgcccagaaa tcttgatttt
     5281 tgttgacaag aaatgttttt gctgtatttc taagcagcat cttgcaatgg agtcacttac
     5341 taatgggtgg ggttaaaaac atcttgctaa ttatattcaa atgaagtctt tattatactg
     5401 tttcttcaat tctaaataaa aaaaaatgga ttacaataca ggcttcatgg atgtagggag
     5461 acaaatactg agaggcactc ttggagataa caaataattg agctgaatgt gaaaattaag
     5521 ccaccagcac cttcattcct agataagaca gatgactgga tctgctctaa agcaaaccat
     5581 aaatctggaa gaaagcttgc cttggagtaa atttgtacaa atgaatatat aggccactcc
     5641 aactcccttt cttcatggtt actgttgcat ttaccacccc acttttcctt cagcttcact
     5701 cctgagtcag ccagaagcta gagccagtga gacgctggca gatgacctca cacacaggct
     5761 ttgcaaggtc aaaggtagcg gtgccaggga aatataatga accaatatcc ttgaaacaat
     5821 aacattttga aacattttgc cttgaaagaa aagtaagtgt gtgtgtgcgt gtgtgtgtgt
     5881 gtgtgtgtgt gtgtgtgtga gagagagaga ttgcatttgt gtgtgaatgt gagtgtgtgt
     5941 atgtgtatgt gtctgtgcat gaatatatgt atgtgtgtgc atgcatgcat atgtacttgc
     6001 atgcatatat atgtgtgtgt gcatgtattt gtatgattgt gtgtatgagt gcatatgtac
     6061 atgcattttt atatgtgtgg gagagatgta tgtgcatgca tgtgtacatg tgtgtgtgca
     6121 cacgtttgtg agtgtgtatg tgtctgtgca tgtgtatata tatgtgtgtg catgcatgca
     6181 tgtgcacttg catgcatgta tatatgtgtg tgtgtgtgtt catgtgtgtg tatgagtgca
     6241 tatgtgcatg catgtgtgta tgtgtgagag aggtgtatat gcatgcatgt gtatgtgtgt
     6301 gcacatgttt gtgagtgtat gcatctgtgc atgcatgtat atatgtgcgt gcatgtatgt
     6361 atgtgcattt gtgtgtgtgt gtgtgtgtgt gtgtagtcct aaggtcaggg ggaagcaagc
     6421 tctgtgcata gcacttcaca agtcagctga cagatactgc aaacacccaa aagacttctt
     6481 acttcacatt atgagagaca ggtatgtccc ttgttccaaa tgtaacctcc cttccaactc
     6541 cattaaaata tcttcctcct tcttttgctc tcatgttctt aacgaggtag ctcagttcta
     6601 ccagctcttc cctccctttt tttgtcctct gttccccctt ctcggccctc atggctctga
     6661 tcctgtcagt ctgcatgtat gcttgtctgt ccctacccct tcccctaatc gtcacttccc
     6721 tcccttcccc ccaaataaac ccccttatac cagatctgtt gcatggagtg acttctcagg
     6781 ggagcacctt ggtatgcccc gcaggtactc cctcactgca ttatatgtga atacacacac
     6841 acacacacac acacacacac acacacacac acacacacaa gccttccgaa agggctaaca
     6901 acaatcttca tgtcagtacc actgaaccat ggaaaagcat ttggggttca atatgggata
     6961 attagaaacc ttactgccaa ggaaactctt gcttttatgc ccacatggac ctaggcacct
     7021 gtatccccag gtcacatata taagagagga attgctaata tttgcacatc cttaatttta
     7081 ttgtaggatg ccacaaatct tgcaaaggag ttgagccaat tcagttttta ccaaaaagct
     7141 atagaagctc ccatcagccc ctatggcagt ctctttaccc tgtggtcctg gcttctcttt
     7201 gatcctggtt tgagttggtg gcattctcta aaatatttta aaagccagat ataattttat
     7261 gtttttattt gccactttag aaaagtttgt ggagacactt ttaagtcagt gttccccttt
     7321 ccatttcaaa ggagagaaag gtcagggtgg gaagagtaaa cgcagtggct tcacggtgga
     7381 ttgtagctgt gaagcgaaaa ctatgccgag ggcaaggagg tgagagacct ctagagatga
     7441 acagattaag aagtcaacaa gctcttccct ctccccttct tgtggtctta tttggccatg
     7501 tgaggaagga agcccttctc cctcacttaa gtgagaagtt tccggacacc tcaattggtt
     7561 gagtgtggct ggccatcgtg atgatgacaa aatggcactc aaccgggtta aataagactg
     7621 gtggaaaaga gctgtcgctg ttcttcagct gcagcaacaa agctaagtcc tctggaaatt
     7681 cagatgaaag gcgtgaggta ccaaaaataa taatttgtca atttagttgt ggagcacaga
     7741 ggacgcgtaa aatgtgggga aaccaaaata gagatcctgg aaggatttta tatttagctt
     7801 gctccaaaac tgcgtttgat ttctaactgt tttaaggaat cgggaataga gatcatagat
     7861 tatgcattgc gggcatagtt tgcaaggatg ctaatagata atgggaatca aagaaaaatg
     7921 ccccggcctc acatcaaaag aacagtgctg agcatgtgtg cacgcacaca cagctttatc
     7981 gaaaaataaa atattgaaaa cgtttatctg catataagcc ttttcaatgt tttggtcaac
     8041 tttctcaatt aaataaccaa ctagctgatg ttaccatagt aaggaagttt tccatgagcc
     8101 actcagacca aagcagatgc ccagctcatg gaaatcacag tctggaaata aacattttta
     8161 aaaattgagg tagactttcc ctacagtaaa atatacatct ctaactttat gaaatttgaa
     8221 gaatgtttga aacacatgtc ctacaagagc tatgtcttat gtaaatgttc atgatgtgtg
     8281 cttgtgcgtg tgtgcttgtg cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     8341 tgtataccac cccagaaaat tccctaattt cctactagca aagccaaggg ctgtttttaa
     8401 atgccatcac atatttcttg tgcccgttac ctaacacttt atgaatgaaa tcaaacaata
     8461 tgtgttattg gtgtaatttt ctcccagatg atttttcttt gtggtttatc tattgtatgt
     8521 caacttgatg caagctatac tctaagagga ggggaacctt agctgagaaa ctgcctccat
     8581 aagattaagt tgtaggcaag cttataaggc attttcttaa ttagtgattg atgagtgagg
     8641 gcccagcccg tgtggatggt gctacccctg cacttgtggt cctggattca acaaaaaaat
     8701 caggctcttc aaaagccatt gaagagcaag cagtatccct catggtctct acatcagctc
     8761 ctgcttccag gtttctgccc tgtttgagtt cctgtcctga cttccttcag tgatggatta
     8821 caatgtagaa atgtaagcca aataaaccct tcactctcca acttgctttt ggtcatggtg
     8881 tttcatgata gcaatagtaa ccctaagaca tccatgctgt gctaccaacc gtagctgagt
     8941 agcaagtgta taatgggagc actacttact ccattctact aatggatacc tgagttatta
     9001 ccttgtttta ctaagttaat tttaaaaata agcaaacaca cacacacact cagagcacta
     9061 aagcttaaga aacaaaaaag aaaaagaaag aaagaaattg ctcatttgac accagaggac
     9121 agaaagcagc taaatgtttt tccataaacc ctttggcaag tgatactagc cgccccctcc
     9181 catctctctc tctctctctc tttcttgcaa acacacataa cagtaaaatt cccgagtcat
     9241 aggatctgtt atgtatggac ctcggggggg aaacttccaa gctctcctaa gtcagtggca
     9301 acttttaagg ttgtagcacc caagaataag agatcaaatc agcccacatt ccaactggca
     9361 cttgatatca gtcctttaaa cttagcttgt cgcaaaggca tgtgtggctg cctattgtgt
     9421 aatgttaaat gctgttccca ggtgactaat catgtcaagg acatgtgcat gtatgcttag
     9481 tccttgcctg gtctcttttg tgacattagt tttttgtttg tttgtttttt gttggtggtg
     9541 gtggtgtttg ttttgttttg tttttaatct acactacaga gcagttgatt ggtctttgtg
     9601 atggtttata tatgcttggc ccagagagtg gcactattag aaggtgtagc cctgttggag
     9661 taggtgtggc tttgttggag taggtgtgtc actatgggtg tgggctttaa gatcctcatc
     9721 ctagctgcct ggaagtcagt attctgctag cagccttcag atgaagatgt agaactctca
     9781 gctcctcctg caccatgcct gcctggacac tgccatgttc ctgccgtgat gataatggac
     9841 tgaacttctg aacctataag ccaaccccaa ctaaatgttg tcctgtataa gagttgcctt
     9901 ggtcatggtg tttgatcaca cttagtaaaa ccctaagtca gtcttagtat atgtttcctc
     9961 gttgaaccct gttaacattt tgtagtaagt aattgacagt gtatgtgtcc tgtctcctat
    10021 tgtattatag gcttttattc tgtatctcag accaacacta caatgctgtg tggctttgaa
    10081 tgccacactc actgtcttag tcagggcttc tattcctgca caaaaaatat gaccaagaag
    10141 caagttgggg aggaaagggt ttattcagct tacacattca aattgctggt tatcaccaaa
    10201 ggaagtcagg actggaactc aagtaggtca gggagcagga gccgatgcag aggccacgga
    10261 ggaatgttac ttactggctt gctacccctg gcttgctcag cttgctttct tatagaaccc
    10321 aagactacca gcccagggat ggcaccacct tccttgatca ctaattgaga aaatgcccca
    10381 cagctggatc tcatggaagt atttccccaa ctgaagcgcc tttctctgtg ataattccag
    10441 cctgtgtcaa gttggcacac aaaaccagtc agtacactca cctacatgga catttacata
    10501 ttttccagtt ttgttctttc tttatattta ttttacaatt gcattgtcaa cttaataaac
    10561 aagcttaata aaacgatgct gagatctgtt tcaatgacgt tgatctgtaa gtaactaaca
    10621 ccttagtgtt atcgactctc ctgctccata gactcacctc tttatcaaag gcttcccact
    10681 taaatgtccc actcccggct aagcaaagtc gtgcactctt tcctttaatc aaccctatgt
    10741 gttctctgcc ttttgatgct actacgaaag gaactgaaga ctttcttggt tagaagtgca
    10801 atttagttgt acgaattgtt tctgaattca gcggccttgc taagttcact ccttggtggt
    10861 aaatacttcc ttttcagtat gaattttttt taaccaaaga aatcatgcca catacaagca
    10921 aaactgtatt gatttctttg cgacactatg tcctgtgttt cttgttcatg gtgagcctac
    10981 tacactggct gtggtggtgg gtgtgacgct gagtggctgt gatgatcgga gtccttgcgt
    11041 ctgacctcag catctgtacc tgcccttcac agagctgaaa tatttacgtg ccctgtagtt
    11101 attttttatt atgataagtg ggcaataagc tcagtcaatc gtcctcgttc ctgttcaacc
    11161 atacttaaca tttctggttc tcctcaatat gtcatattta tatgtttctt ctgatttgtt
    11221 ttctttatcc tgtttgtaat tctggaagat agattagtat aattatagaa gttctatcat
    11281 gttttttgtt tgactatagc ctcatagcat tcatctattt cctaaaagaa ttgatgttga
    11341 tgcaagatta gaataatttc tgaaagcata tgaaggactc ctgcagtcac atgacctaga
    11401 ctttcagtaa agacaaactt ctggattttg tgattggttc agtatttctt tgcttttgag
    11461 ttggagaaat tgttgatgcg aacttgttca caatccctta ttatcttgtt actgtgtata
    11521 gaatctggca tattgctcca ccactgtcct ggtattggtc atttgtgttt tatctgtaac
    11581 aaagcagaaa acacaagcct ccacaaactg aaggttatca gccaataacc ccctgaggcc
    11641 aaaaaaaagt taacaaagag aaataagaaa aatcataatc tctcaagtac atgatctaca
    11701 aatttatctg acccatattt agaaagcaaa atcagccaat tgaaatagac aagattcaac
    11761 ttagatgttg gtattataaa gataaatcta aattctgacg ggggtggtca caatgagttc
    11821 atagatgggg agtggtcaca gtgagttcac agttggggga gtggtcacag tgagctcaca
    11881 gttgggggag tggtcacagt gagttcacag acggggagtg gtcacagtga gctcacagtt
    11941 gggggagtgg tcacagtgag ttcacagacg gggagtggtc acagtgagtt cacagttggg
    12001 ggagtggtca cagtgagctc acagttgggg gagtggtcac agtgagttca cagatgggga
    12061 gtggtcacag tgagctcaca gatggggagt ggtcacagtg agttcacaga tggggagtgg
    12121 tcacagtgag ttcacagttg ggggagtggt cacagtgagc tcacagttgg gggagtggtc
    12181 acagtgagct cacagttggg ggagtggtca gagtgagttc acagatgggg agtggtcaca
    12241 gtgagttcac agatggggag tggtcacagt gagttcacag ttgggggagt ggtcatagtg
    12301 agttagcaga tggggagtgg tcacagtgag ctcacagttg ggggagtggt cacagtgagt
    12361 tagcagatgg gggaatctca gcagagaaat ggaaactaag aaaaaaatag aaaatctaga
    12421 actgaaaagt acaatatctg aaatagaaaa ttcactgaat atgggcttag aagcaaattc
    12481 aagttggcag aagaaagtgg caaaggacga aatatatata tatatatata tatatatata
    12541 tatatatata ttcgggagaa attatccaag ccgacgaaca gggagaaaga ggcttggtag
    12601 gtggcgagtg ctgcagcaag tcatctaatg catgtgcact taggatccaa ggacaagaaa
    12661 agaacaggag agagaaacac gacagcagcc aactcctgca acttgaagag atttaaattc
    12721 ccagcccttt cttgccagtg tcaggctgtg ctgaagaatt gttttaatct ctccagtcct
    12781 ccagttcttg ctttcactgg cctctttatc tgtttctcgc acatggacag aattttgcca
    12841 aagatttgca gaatggactt gcggattctg aggggtctct ttaccttcca gggtttctcc
    12901 cccttggttt ccagcaccct gagtagcctc aaactccgtt ctgtcaacct tcaattctgt
    12961 aagaccatgg ctctctgctc tgtatcacac tgcagagcag gaaaagctct ctcaggatac
    13021 taaggcaaag cccacacaag tgtgttgttg ctgcttcctc tgccttgcct ctgtctctct
    13081 ctgtctctgt ccctccctct gtctctgtct gtctgtctat ctgtctcccc ccctctctct
    13141 ttctctgtct ctctcccttc tctcctctct cctctgtcct ccttttctct tgttgatgat
    13201 atatacacac atatgtattc acatggaatc aagagatgaa cttcaagtat cttcctagat
    13261 tgcatttcac ctgattgttt cctatgtata tgtatatata tatgcacata tatattatgt
    13321 atatatatga atgtgtgcca acattcatgt atgtatatat gacttgtgac aacatgtatg
    13381 ccgagtgcct gagtaagtca taagatggca taggatatcc tagaactgaa attacagttg
    13441 gtcgtgagcc gcccatgcac gtgctaggaa ccaaacccag gtcctctgca agagcattaa
    13501 gtgttcctaa ccatggacct atctctccag cccttccacc ttattttttg aggacaggat
    13561 ctctcagtca cccaggagcc ccccaattca gcggacttgt cagcgagctc taggcatctg
    13621 cctttctaca ctcccctgag cactgaggct ccagactctt tctgtgcctc gacagcacta
    13681 tgttgaccaa gcctgccagc cctatggtac ctttctttaa atggccgaat ccctggttag
    13741 taacttctaa ctttcttctg atctcggggg tctctcatca ctagaaatga tgcttgtgtg
    13801 tgctagtcta gtgtgagctt gtctgtcact accaaaatat tcctgaggta ctgttccaag
    13861 gaggccggat ttatacaccc cagcatttcc actggcgtaa gtactgtgct cggccataag
    13921 gcaacacctc agagcctcct gataaccaaa ttcccttcct tcccaaataa tggaagccca
    13981 ctttgatgtg aaacaacttt ggataccact ttttatggca atgcaagctc tagctggtga
    14041 ctaaagagta tgtaaatcat ggagactttg ggtggtctcc tttaagggga accacacagc
    14101 agaaggaaga tcttttctct ccttcctgcc atattccatg acatagtgat tagaatcccg
    14161 catcaacctt cgatcatgaa ccaactgcaa aaagatggag cagagactga aaagttgggt
    14221 gagtctctcg ctctattcac caggggtgta ccggactgcc cagttgatgc taattctgat
    14281 gtaaaaaaaa aaaaaaaaag gaggccccac acaaatcaca aatgcaccaa taaatacaag
    14341 tgtatccctc caagagaact ctttccaaag agtaagtggg taaggctgaa gactcgttat
    14401 gatgcaccca aggagacccc tgtctgggcc ttccccttcc agtctattct ggggctgcag
    14461 ttttatcagc tgcagtgtta aggaaaacaa cctaatagcc tttccctatt gcaatagatg
    14521 tctccacact atagataata ttacgtcttc gctaattcta aggatctaat ggagacttta
    14581 tgtttgtatg taatttgttt aatgcagtca caggtctttg ctgctaaaca agccgcccct
    14641 ccccgttgtt ttctaggaac cttaaacaac agcttctgtt cccctgggtt tcatagatct
    14701 tagtccatcc acaaggagga atggaaatgc gaagaataaa tttttagggt tctgctctca
    14761 aatattcccc taatttttaa gaggctggag ccagtcacgg atacaagtaa aacacatttc
    14821 ccccaatgct gagtctgaga ctgtgaattg agacagggaa atggttttct tttctagatg
    14881 actatttttc aaactagaaa tatgttttgc atcaatgatg tgttaaggtc aagtcaagga
    14941 aagagacaat atgtcccatg tcacggagac cgggataatg agagtgttct ctgggagctg
    15001 gcgtgaggct gttcatttca ccggcgaaag gttacaccag acagattgtt tctcatttga
    15061 tgtcttaaat taaaccgctg acatggcctg cctcaaagtt agaagcttct gttttcacca
    15121 aacagaccct aaaggaaaat tcctatttga gagagttggt ctccaagctg cagcctttga
    15181 ggattttctg ttttcgagtc ttgcttagga attcaaacag gttttcaact gctgggcagc
    15241 tcctaatgtg atcgtgaagg ggggcccggt ggatctgagg cttggcagtt tgttaaagtg
    15301 ctgtgtagga tagaagcaag ataaatgttg tctaagtaag attcagaaac agtcatatac
    15361 aagatgcaca cgtgttcaga caggaaattg ctgctgctac aaagaatcca tctacctatt
    15421 tgagatgtac tttggtcatc ccctttgttc taatcctggc ttgccctcct caatgaccat
    15481 tttgcctgcc tctaaaattc agaaatcaaa cgttacggtg agagctcagc tgaccagcaa
    15541 cactaatatt tcagcatggc aggggctggc ccaggcaccg atgtgcagct gaaccaggtc
    15601 cccagatggt tgaggaatcc tggcccacag atcttaaaga aacgtagtgg tgctatgcca
    15661 gacacaagat ggaggctggg gaactgggca gtaaatatct taggcaaggc ctgcttacag
    15721 ggcactttcg ttgagatagg gtagggagag catataataa ataaggggac agctgggaac
    15781 atttctggtg gtgttaagga ttaggacagg gaatcagaga ataatggggt ggggtgagga
    15841 acactactat aaatagtgag caaggaaaac cagctagaga ggaaaaattg atagaaagag
    15901 ataccaagag aaacaaagta caaagtatcg ataaaaagag atacaaagga aacaaagtac
    15961 aaactagtgg gtaaggggtc agaaaatgta catctggccc ctgatctccg gttctttgaa
    16021 tatcagcaac tacttcatgt cctcatctgt caactaggac taaaaagtac aaactagtgg
    16081 gtaaggggtc agaaaacgta cattctggcc cctgatctct ggttctttgt atatcagcaa
    16141 ctacttcatg tcctcatctg tcaactagga ctaaaatgac tcatgggtga tgggagaaaa
    16201 ttgtgtgtaa tagctgtgtg aggtactgct ggcagcccca gccaaccccc acccccaccc
    16261 ctggccaggc tgtaggctcc ttgacctttc cctctgactc acacggggac atccaaggac
    16321 agtgtgattt agagatgcaa agggaggtat taagagttgg gctttgcatc cttaatctac
    16381 agcttccctg agcaccagac acaaacttgg cttcagttcc cagattggag tttcttcccc
    16441 ccccgggggg gaggggggct tttcacaatc ttcgggtgat ctggacctta aagccactgc
    16501 ctctaccatc tatctctaca tcatcttacc ttagcctatg gttcttcttc cccaagctga
    16561 cactcccaaa ttggtaactc ttggcacatg atcttcatct tcttgtgccc attcatttta
    16621 ggctgtatga tgtactcggt gactgtcacc tttttgacac ctgaagctgt gatttgagac
    16681 ttcttgtaca actgtcagag tgtttgggcc ttctgtcctg actactgggt caggaggaaa
    16741 gggtgtccca cccctgtgat gtattccaga atagatccca agttctccca gtctgcattt
    16801 cagatcatgc cctcttattc cccagtcaca acaaattgcc tctggttaat ttgagaaatg
    16861 tctgtatttg gtgtttctgt aattttattt tgtgtttcag ttgagtaagt gttgctgaat
    16921 atctgtagaa tgtgtgataa tttttgtaaa aaaaaaaaaa actcaataaa agaaacatta
    16981 ccatagaaaa aaaaaaaaaa a
//
