LOCUS       NM_001142642            4737 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus fibrosin-like 1 (Fbrsl1), transcript variant 1, mRNA.
ACCESSION   NM_001142642
VERSION     NM_001142642.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4737)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4737)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4737)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   4  (bases 1 to 4737)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (bases 1 to 4737)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY733978.1, BC059932.1, CX204847.1, BU614458.1, BP764457.1,
            CA321720.1 and AW492835.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                BY733978.1         2-18
            18-1468             BC059932.1         1-1451
            1469-1742           CX204847.1         1-274
            1743-1876           BU614458.1         51-184
            1877-3700           BC059932.1         2663-4486
            3701-4034           BP764457.1         38-371              c
            4035-4433           CA321720.1         185-583
            4434-4737           AW492835.1         1-304               c
FEATURES             Location/Qualifiers
     source          1..4737
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 53.51 cM"
     gene            1..4737
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /note="fibrosin-like 1"
                     /db_xref="GeneID:381668"
                     /db_xref="MGI:MGI:1920907"
     exon            1..624
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     CDS             337..3432
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /note="isoform 1 is encoded by transcript variant 1;
                     AUTS2-like protein"
                     /codon_start=1
                     /product="fibrosin-1-like protein isoform 1"
                     /protein_id="NP_001136114.1"
                     /db_xref="CCDS:CCDS51609.1"
                     /db_xref="GeneID:381668"
                     /db_xref="MGI:MGI:1920907"
                     /translation="MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGEEPEPSPGK
                     ENAGLHGAPPQRPTPLRAARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALK
                     PHERKEKWDQRLVKKPRESENCPSAELSENRQPLEVGSPGQDAEPSCDEGTRKVPLQP
                     SKQMKVTMARGGDRNSDDDSVLEASSSQRSSSREQLSDSSAQAVSGRGYSCDSESGVD
                     DKASVGSEKLFAPAPDKGSGRGEKSEAKAGAVPKVSGLERSSELSTEAFLPATAPAPS
                     GPAPGTPASPLVKREAPVVPHHVPQPQLTPQHRGSLPTHVPLSLGAFVGPGPGPGQVA
                     SSSLHLHSLSRSSSTVSGTPLGLAKHVTLSPHGPGPHLSTSHLALRSQAQHQHHAAAM
                     FAAPPTLPPPPALPASSLVIPGHPADASLLISFNQPIMYCQPHSGILIDHELLRQELN
                     TRFLVQNAERPGASLGPGALLRAEFHQHTHQHTHQHTHQHQHTFAPFAGLPPTPLMPP
                     TAPSPFDKFSPKLDSPYFRHSNTSNSIEITGRSSAVHTFLQKAPGVSDPYRTAVRKPG
                     KWCAVHVQIAWQIYHQQQKMKMQLDPHKLEVGTKLDLFSRPPAPGMFSGFHYPQDLAR
                     PLFSSTGATHPTANPFGPSAHHGSFLPTGHLTDPFSRSSTFGGLGSLSNHAFGGLGSH
                     ALTPGSSIFAPKEGTALLGLPSPHDAWNRLHRVPPSFPTPPPWPKPVDTERLSALTNH
                     DREPDKGQEEHERDLLEKTRLLSHGSPVAPVGHPISSLLQRGSGELSRPGVLTEREAE
                     TRVKESHSPSKEDGAKLAARPPSPYCKAALGDCLRLAGLLGRESGKQTPDRPQGDVKV
                     KEERREDETPDLTGVSVHSTATHMGLGTAGFVWDPPRDTYRGLELPRRSFPAPPPAAG
                     PSPFELSERAYRDREPHDYSPERLQEVRREELERARVPDSDAAALLPAVHYPRLAPGA
                     LHGALLARTPPAAAVLGAPPPLVTAGGVPTPPAHPRTTLGPGEAREYSPACNPPEVEA
                     R"
     exon            625..825
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            826..930
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            931..966
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            967..996
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1042
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1367
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1588
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1657
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1875
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1876..1926
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1927..1995
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2025
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..2097
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2227
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2305
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2306..2389
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2594
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     exon            2595..4723
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4012..4017
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /note="hexamer: ATTAAA"
     polyA_site      4037
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /note="major polyA site"
     regulatory      4700..4705
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
                     /note="hexamer: AATACA"
     polyA_site      4723
                     /gene="Fbrsl1"
                     /gene_synonym="2410025L10Rik; Gm1049; Gm29766; mKIAA1545"
ORIGIN      
        1 agttgttatc cgctctggtc gctgccacta ctgtgtctgc ctcacggtcc cggtgctcag
       61 aagctccgcc acccgccgcc ttctgccgct gcccgccggt cgccatgggc cgtgtccctg
      121 gggacctggt ctagggtcgc cgagagaccg ccgcactccg atgcgcggga cccggggtcc
      181 tagcccgcgc ggcgtccggt gctgagagcc cgcgcccggc atgcccgccc cggtcccgag
      241 cccgccccgg ccccgagccc gcgcggcgcc ctcgcagccc ggcggcacgg cgtagcaggc
      301 ggtgcggggc gccaaggtca ccgccgcggc gccgccatgg aggccaaggt ccggccaagc
      361 cggcgttcgc gcgcgcagcg agatcgcggc cggcgtcggg aagccgcccg ggacgcccgc
      421 gcccagagcc cgtcgtcggg tgaggagcca gagcccagtc ctggcaagga gaacgcggga
      481 ctccacggcg cgccgcctca gcgccctacg cctctgcgcg ctgcgcgccc cccgcggcgc
      541 cgtcgccgcg agtccagctc gcaggaggag gaggttattg acggcttcgc tatagccagc
      601 ttcagcaccc tggaggccct ggagaaggat atggctctga agccacatga acggaaggag
      661 aaatgggatc aacgccttgt gaagaagccc cgagagtcag aaaactgtcc atctgcagag
      721 ctgagcgaga acaggcagcc cctggaggtg ggcagtccag ggcaggatgc agagccctct
      781 tgtgatgaag ggactaggaa ggtccctttg cagccctcca aacagatgaa ggtcacaatg
      841 gccagagggg gtgaccggaa cagtgacgat gacagtgtcc ttgaagcttc cagctctcag
      901 cgtagcagct cgagggagca gctaagcgat agctcggcac aggcggtttc tgggagaggc
      961 tactcatgcg acagtgagag tggcgtggat gacaaggcat ctgtgggctc tgagaagctc
     1021 tttgccccgg cacctgacaa aggttctggg agaggtgaga agtcagaggc caaggcaggg
     1081 gcagtgccca aggtgtcagg cctggagcgc agcagtgagc tcagcacgga agctttcctg
     1141 cctgccacag cacctgcacc ctcagggccc gcgccaggaa ctccggccag ccccctggtg
     1201 aagagagaag cgcccgttgt acctcaccac gttccacagc cacagcttac cccgcagcac
     1261 cggggctcac tcccaacaca cgtgcctctg tccttgggcg ccttcgtggg ccctggccct
     1321 ggccctggcc aggtggcatc cagtagcctg cacctgcaca gcctcagcag gagcagcagc
     1381 acggtcagtg gcacccctct gggcctggca aagcacgtga cactgtctcc acacggcccc
     1441 ggcccccacc tgtctacctc acacctggcg ctcaggtccc aggcgcagca ccagcaccac
     1501 gccgcggcaa tgttcgctgc ccccccaaca ctgcccccgc ccccggcgtt gcccgccagc
     1561 agcctggtca tcccaggaca ccccgccgat gccagtctgt tgatctcatt caaccagcca
     1621 atcatgtatt gccagcctca ttcggggatt ctgattgatc acgaactgct caggcaagag
     1681 ctgaacacgc ggtttctggt gcagaacgcg gagcggcctg gcgcctccct gggcccgggg
     1741 gctctgctgc gggccgagtt ccaccagcac acgcaccagc acacacacca gcacacacac
     1801 cagcaccaac acacatttgc cccctttgca gggctgcccc cgacgccgct tatgccgccc
     1861 accgcaccct cgccgtttga caagttctca cccaagctgg acagccccta cttccgacat
     1921 tccaacactt caaactcaat cgaaataaca ggccggtcga gtgcagttca cactttcctg
     1981 cagaaagccc ctggggtgtc cgatccgtac cggacagcag tcaggaaacc agggaagtgg
     2041 tgtgcggtac acgtgcagat cgcctggcag atctaccacc agcagcagaa gatgaagatg
     2101 cagctggacc cccacaagct agaggttggc acaaagctgg acctgttcag ccggcccccc
     2161 gccccaggca tgttctctgg gttccactac ccacaggacc tggcccggcc cctcttctcc
     2221 agcacaggtg ccacccatcc aactgccaac ccattcggac cctcagctca tcatggcagc
     2281 ttcctgccca ctggtcacct gacagaccct ttcagcagat ccagcacttt cggaggcctg
     2341 gggagcctga gcaaccacgc gtttggaggt ctgggcagcc atgcactgac accaggaagc
     2401 agcatctttg cccccaagga gggcacagct ttgctcggcc tgcccagccc ccatgatgcc
     2461 tggaaccggc tgcaccgggt gccaccttcc tttcctaccc caccgccatg gcccaagcca
     2521 gtggacacag agcgcctctc agccctgacc aaccatgacc gagagcctga caagggccag
     2581 gaagagcatg agagggacct cctagagaag acgcgcctgc tgagccacgg gtcgcctgta
     2641 gcaccagtgg gccaccccat cagcagcctc ctacagcggg gctccggtga gctgagccgc
     2701 cctggggtcc tcaccgagcg tgaggctgag actcgggtca aggagagcca ctcacctagc
     2761 aaagaggatg gcgccaaact ggctgcgcga cctccgtcac cctactgcaa ggcagccctg
     2821 ggcgactgcc tacgcctggc aggcctactg ggtcgggagt ccgggaagca gacgcctgat
     2881 cggccccagg gcgacgtgaa ggtcaaggag gaacgcaggg aagacgagac accggacctc
     2941 acgggcgtca gcgtgcactc cacagctaca catatgggcc tgggcacagc aggcttcgtg
     3001 tgggatccgc cgcgcgacac ctaccggggc ctggaactac cgcgccgctc cttcccagcc
     3061 ccgccgcccg ctgcgggacc ttctcccttc gagctctcgg agcgcgccta ccgggaccgc
     3121 gagcctcacg actacagccc ggagcgcctg caggaggtgc gccgggagga gctggagcgc
     3181 gcgcgcgtgc ccgattccga cgccgccgcg ttgctgccgg ccgtgcacta cccacgcctg
     3241 gctcctgggg cgctgcacgg ggcgctcctg gcacgcaccc cgccggccgc cgcggtgctc
     3301 ggtgcgcctc ctccactggt gactgcgggc ggggtcccca cgccgcccgc gcatcccagg
     3361 acgacgctgg ggcctggcga ggcacgggag tactcgcccg cgtgcaaccc tcccgaggtg
     3421 gaggcgcggt agtcccggcg tagcgagctg gctcacttaa attcttggga cctgagcaca
     3481 gttcccctga gtcccggagc agcgccacgc tgcagcctac atagtcgagg acttttcgct
     3541 tttctggggg tgacttcatt ttccgagctt gcgattaggt cactgggaaa aatttagctt
     3601 tgtatctttt cccccttcac aagtgacaaa agcattttta atggttttgt atttttctta
     3661 attttgtgct ctaacgacat tttaaagaac aaaaaaaaaa tttttttttt aagttgggat
     3721 ttgcagttta acttctcaga tcccatttga gccccagggt ttgtcttatt tatggaaaga
     3781 aatggtcttt ctgtccagcg cactgtgagg ctccgaactc aggcccggct ctggccttcc
     3841 cttggtactt ggaaccgacg ttacagatat atattaaaat agtaattaat aataatgtac
     3901 aaaactttgg gttttctgcc ttattctatt atgcatagtt gtaagaggat ttccttggtt
     3961 tgttttttta ggaaaaaatg taaatactct gttgatataa ttataaaact tattaaattc
     4021 ttaacctgga cagtctataa caagtttcta gaaacccctc tggttatttg tgtacgtggt
     4081 cacaaaaacc cacccggctg tcagttgtga acacactcaa cagtttaact gcaacaacta
     4141 tccttcaact atgcaagcct gggaggcaga gcgggatatt cagggggaga cggtctctga
     4201 gcttcctacc aaggtggttg ggccttccgg agagccacac ttgtggatgt ttgcttagac
     4261 tcacagtggg cttcaggact ggctggctct agtcacaagg accaacctgc acccgtgtgc
     4321 tagtcttact gcagtgttct cagaatttgt gcaggccagg cagaatctta gacgttcaag
     4381 agtctaaagg ttggttacca gaagacacag tttttttcct cccagcgccc agcatctggg
     4441 cgttgccctc cctgtcacta agcctctcat ccctcctttg gttttggttt tgcactcctg
     4501 ccctctccag ctttcccgtg tgctgtgtgt gtggtgtgtt gtcagcttgt cctttttggt
     4561 tctcaaccag cacatttatg ctgaatcaac actcggcacc ccgtctacta ctctgttccg
     4621 ttccttccag cctggtttcc gcagtggact ctggttattt taaatagtct gtcttcgtgt
     4681 cagtcgacac agagagataa atacaacctt gatttggatg aaaaaaaaaa aaaaaaa
//
