LOCUS       NM_001004147            1522 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus fibrillarin-like 1 (Fbll1), mRNA.
ACCESSION   NM_001004147 XM_111253
VERSION     NM_001004147.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1522)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BE648485.1, BC052068.1 and BU701095.1.
            
            On Jun 2, 2007 this sequence version replaced NM_001004147.2.
            
            CCDS Note: This locus represents a retrotransposed intronless copy
            of the fibrillarin locus on chromosome 7. Although this locus could
            be interpreted to be a fibrillarin pseudogene, there is specific
            transcript support for this location and the CDS is intact compared
            to that of fibrillarin. Assuming that the transcript is translated,
            and due to lack of experimental evidence to say otherwise, the
            protein is represented in this CCDS.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-310               BE648485.1         1-310
            311-1491            BC052068.1         1-1181
            1492-1522           BU701095.1         1-31                c
FEATURES             Location/Qualifiers
     source          1..1522
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 21.96 cM"
     gene            1..1522
                     /gene="Fbll1"
                     /note="fibrillarin-like 1"
                     /db_xref="GeneID:237730"
                     /db_xref="MGI:MGI:3034689"
     exon            1..1505
                     /gene="Fbll1"
                     /inference="alignment:Splign:2.1.0"
     CDS             451..1395
                     /gene="Fbll1"
                     /EC_number="2.1.1.-"
                     /note="protein-glutamine methyltransferase"
                     /codon_start=1
                     /product="rRNA/tRNA 2'-O-methyltransferase
                     fibrillarin-like protein 1"
                     /protein_id="NP_001004147.1"
                     /db_xref="CCDS:CCDS36128.1"
                     /db_xref="GeneID:237730"
                     /db_xref="MGI:MGI:3034689"
                     /translation="MKPAGGRGGWGWGGGKGGSKGGDTGSGTKGGFGARTRGSSGGGR
                     GRGRGGGGGGGGGGGDRQRRGGPGKNKNRRKKGITVSVEPHRHEGVFIYRGAEDALVT
                     LNMVPGVSVYGEKRVTVMENGEKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYL
                     GAASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYR
                     MLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASE
                     VRKLQQENLKPQEQLTLEPYERDHAVVVGVYRPPPKSK"
     regulatory      1485..1490
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fbll1"
                     /note="hexamer: AATAAA"
     polyA_site      1505
                     /gene="Fbll1"
                     /note="major polyA site"
ORIGIN      
        1 ttacacatag gtttcctgct gacacacggg agagcaagaa actaagaaac tcaaggacta
       61 gtggatgcgc gcttcccatc tctctgccac agagacgctt ggccactgcg agatccaggg
      121 aaagaagctg gagtccctgg gaaagcagag aataaatacc agcagactcg agagaaggca
      181 aagggttaca agtgagcagg ctgtgtctgc gcgcagctgg tgcagggggg cttccggggc
      241 tacaggggct acaaaacggc tgtgatgcaa tcacgcaagt caccgcgtca aagcgtggat
      301 ccggggatgt gcgcaccgcg gccccctgca tcccgctgcg gctaatcctg cgggcagccg
      361 ccgccaacaa tttgtcccca ttccgcagca accgcccggg tccctcgcga tccccgacca
      421 ccgcggcagt tcctgagagc tgcgggggcc atgaaacccg cgggcggccg cggcggctgg
      481 ggctggggtg gcggcaaggg aggcagcaag ggaggtgaca cgggctcagg gaccaaaggc
      541 ggcttcgggg cacgcacacg cggctccagc ggcggcggcc ggggccgggg acgaggcggc
      601 ggcgggggcg gcgggggcgg cggcggcgac aggcagcgac gcggcggtcc aggcaagaac
      661 aagaaccgcc gcaagaaggg catcacggtg tcggtggagc cgcatcggca cgagggcgtg
      721 ttcatctacc gcggcgcgga ggatgctctg gtcacactga acatggtgcc tggagtctcg
      781 gtgtacggcg agaagcgcgt caccgtgatg gagaacgggg agaaacagga gtaccgcacg
      841 tggaatccct tccgctccaa attggcagcg gccatcctgg gcggcgtgga ccagatccac
      901 atcaagccca agtccaaagt gttgtacctg ggcgccgcct ccggaaccac tgtctcacac
      961 gtctccgaca tcatcggccc cgacggcctg gtctatgcgg ttgaattctc ccatcgcgcc
     1021 ggccgcgatc tggtcaacgt ggccaagaag cgcaccaaca tcatcccggt gctggaagat
     1081 gcccggcacc cgctcaagta tcgcatgctc attggcatgg tggacgtgat cttcgccgat
     1141 gtggcccagc cagatcagtc gcgcatcgtg gcgcttaacg cccacacctt tctgcgcaac
     1201 ggaggccact ttctcatttc catcaaggcc aactgcatcg actccacagc gtctgccgag
     1261 gccgtgtttg cttctgaggt gaggaagctg caacaggaga acttgaagcc acaggagcag
     1321 ctgactctgg agccctacga aagggaccac gccgtcgtcg tcggggtcta tcggccccca
     1381 cccaagagca agtagcagca gcagaaacca gggaaggtgc ccccgcgctg ccacaagact
     1441 gtgtctttgt gcctgtccta gtgcgttgtt tttctattta ataaaataaa caattcccaa
     1501 gtgtaaaaaa aaaaaaaaaa aa
//
