LOCUS       NM_175234               9342 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus failed axon connections homolog (Faxc), mRNA.
ACCESSION   NM_175234
VERSION     NM_175234.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9342)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772187.6 and AL772278.7.
            
            On Feb 7, 2008 this sequence version replaced NM_175234.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144924.1, SRR7652917.752152.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-504               AL772187.6         214395-214898
            505-640             AL772187.6         219702-219837
            641-837             AL772278.7         3352-3548
            838-1061            AL772278.7         13104-13327
            1062-1178           AL772278.7         37046-37162
            1179-9342           AL772278.7         47958-56121
FEATURES             Location/Qualifiers
     source          1..9342
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 9.2 cM"
     gene            1..9342
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /note="failed axon connections homolog"
                     /db_xref="GeneID:76132"
                     /db_xref="MGI:MGI:1923382"
     exon            1..504
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             239..1468
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /codon_start=1
                     /product="failed axon connections homolog"
                     /protein_id="NP_780443.2"
                     /db_xref="CCDS:CCDS51130.1"
                     /db_xref="GeneID:76132"
                     /db_xref="MGI:MGI:1923382"
                     /translation="MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIA
                     FPLQDYGGIMAGLGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQELDSKDAIIL
                     HQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNNEKVSGT
                     EFIIDFLEEKLGVNLNKSLGPHERAVSRAVTKMVEEHFYWTLAYCQWVDNLNETRKML
                     SLSGGGPFSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGD
                     KKYIMGPKLSTLDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEW
                     HHDDDNTIYESEESSEGSKTHTPMLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSL
                     FDSDVEMDDYTDHEQCK"
     exon            505..640
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            641..837
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            838..1061
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1178
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..9342
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6227..6232
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6246
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /note="major polyA site"
     polyA_site      9328
                     /gene="Faxc"
                     /gene_synonym="6230409E13Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctgacacaa agagcgcctg cgagaggcct cggccaggga ggccggcggc cgccgctgcc
       61 tcgccgggcc cgggggccca gccatcccag atctccgctc gccgtccgcg tccttccgcc
      121 gtcgcctccg cccgcgcccc ctgcgcaccg ctgaacccgc ccgctcgccc gggcgccggc
      181 ctcttcccat gcgggcggcg cgggccctgg gaggggcgcc cggagccagc cgcgcagcat
      241 gcactggggg gttggctttg cctcgtccag gccgtgcgtg gtggacctga gctggaacca
      301 gagcatctcc ttcttcggct ggtgggccgg gtccgaggag cccttctcct tttatgggga
      361 catcatcgct ttccctttgc aggattacgg tgggatcatg gcagggctgg gctcggatcc
      421 ctggtggaag aaaacccttt atttgaccgg gggagctttg ctggccgcgg ctgcgtatct
      481 gctccacgaa ctcctggtca ttaggaaaca gcaagagctc gactccaaag atgctattat
      541 tttgcatcag tttgcaagac ctaacaatgg tgtccccagc ttgtctcctt tctgtttgaa
      601 aatggaaact tacttaagaa tggctgacct accctatcag aactattttg gtggaaaact
      661 ctctgctcaa gggaagatgc cttggattga atataataat gaaaaagtgt ctggcacaga
      721 attcataatc gactttctgg aagagaaact tggagtgaac ttaaataaaa gcctcggccc
      781 ccatgaaaga gccgtctcaa gagccgtgac caagatggtg gaagagcact tctactggac
      841 gttagcttat tgccagtggg tggacaatct caatgagacc cggaagatgc tgtcacttag
      901 tggcggcggt cccttcagta acctgctcag gtgggtcgtg tgccacataa caaaaggaat
      961 tgtgaagcgg gagatgcacg gccacggcat tggccgcttc tcggaggaag agatttacat
     1021 gctgatggag aaggacatgc ggtctttagc agggcttttg ggtgacaaga agtacatcat
     1081 gggacccaag ctttccactc ttgatgccac tgtctttgga cacttggcac aggcgatgtg
     1141 gaccttacca gggacaagac cggagcggct aatcaaaggc gagctgatca acctggccat
     1201 gtactgcgag aggatcagga ggaaattctg gcccgagtgg caccacgatg atgacaacac
     1261 catttatgag tctgaggaga gcagcgaggg cagcaagact cacacaccca tgctggattt
     1321 tagcttttac tccaggacag agacctttga ggacgagggg gctgagaaca gtttctccag
     1381 gaccccagac acggatttca ccggacactc tctctttgac tccgatgtgg agatggatga
     1441 ctacacagac cacgaacagt gcaagtgatg ccccatcacg gagcctcgtc ctcaggagcc
     1501 accgctccct ggggttggtc tgatttccca gatagaaatc catttgagct gggaggagat
     1561 cttcaggcct ggaccagttt tcacatgcta actggactat aagccgcctt atttcttttc
     1621 cttgtttttc gtttttgtac aaacaaaacc agaaccattc agatggctcc gtctaaaaca
     1681 gacaaaacaa atatcagcat ggtacctgaa atccattttt gttttcatta gaaaaccaat
     1741 attgtgtggg agggcaggta cacgagtggg ttgtcaactg ggtgttctat tgatcctttt
     1801 caacggggga cttggttgtc agatggattc ttgaccatct ttcatcaact ggggttttaa
     1861 gtaatgagaa ataccatcag aaaagacata ggagctcatg tcccttggct gctgttgtac
     1921 gtgtgtgtgt gtacttgtat gtcgagacag aagtcaagtg aagtccacca attttcattg
     1981 gatggctgtt acttgtgcgg cgctgagtgg gggtgctaca caacacgagt ttcattatca
     2041 accctgccgg tgactagctg tgtggttcag ggcaggtcct ttaactattg tgtgcctcat
     2101 ttctcccacc tgtacagtgg gggttacaat actctccacc tacctacctc acaggggtgt
     2161 tgtggggact cacgtggcag cattagtgtg atgctttaaa cctctgggaa gtggtgcaac
     2221 acgaacctat tttcttcttc atcgtgcttc ataaatgtta gggtcggagg gcaaaggact
     2281 ttcatacttg ggcaacaagt gcagtcactt gccaaggctg tgcagatgaa acacacacaa
     2341 aaccaattag gactgtgcca tttctccttg tgactttgct ggcggaactt tggaaggagc
     2401 ttggcaaatc agcagcagct acgcatggtc ctcagccctg tgctttaaga acagcatctc
     2461 ttcctttgcc gggtgcattg gaatggggct ttgctgcccc gcaagtgcta acttacctgt
     2521 gtctattgat ttggagaggc taaagcttag gaccttggca gcttagcaga gataaaggag
     2581 agcagttgac tctgtaggca gaagcttgtc aactgttgta gatttttttg aaggttgaga
     2641 tgcgttggga agagaagcat gaaagtgttc cttgtgtctg agtcctctgc agtttccttg
     2701 tcaggtgtcc ccctgtggtt gggtgacagc atggtatcac tgacaccaag ccctagtgtt
     2761 tcatgatcgc acatcccttc ccatcacccc tctccctgtt ctctctcacc acgagcctct
     2821 gaactggtgg gattttcctg tatttgtatt tgtctctgaa gacagcattg gatagcttag
     2881 ttcatttcac aggcagttgt gggccaaggg ttctgtgtga tggctgtgga tttgggctgt
     2941 aagacttaac tgcacaccaa cggctttgct tctgaccgtc ggggtaagga tcacttcaca
     3001 tagggttgca gaggcccttt gaggatagaa gtttctgaga agttaatgta ctttgctaaa
     3061 aaagtaaact ctctttaatg tagctgttcc acggaaatct ttagggtgtt atccattttc
     3121 aaagaggaag tgttttgaag atgtttgcca cctaggtagc catagggcat atggaaatgg
     3181 gaataatgtt gaactcctaa gttagaaatt cttacctgta caaaccttag ctatgaatat
     3241 tttgtattaa aaccattcct actaggaggg cctgtttgat gaggagtgtg agagagggga
     3301 gaaagtgtgc atgagtaggt gtgcttgggt gtcagtgtca tttgggtgtc tcctggtgtt
     3361 ctgagcaact ggtagcaggt ctgtgtgact agggaatctc ttgaacagaa catggagagg
     3421 agggctgtgg acctgactct gcacccattt tcttgcttgc ttccctttct cattgggaag
     3481 aaatgcctga cactttgtag ataagcaagc tagtcttacc gagtgatgct gttccctgta
     3541 aggatgtttt cagtatgagt gtgtggatga atagctgctc atttatgcat tacttggagg
     3601 gaacctcctt agatagacaa tgtttgttgt gaagttgtag cgcaacttat ttgaccacgg
     3661 tacccttaga gaggggtgat gaacaggcat tgccaactgg ggtcatgggt acttggacag
     3721 cttagagctg ggtacagatt taagtagaac ctgagaacat acccctgtat ccatcttcca
     3781 tatgggttat tgaaacaaaa tgaccaagaa aaattacagc gatgtgggtc tttgtgggag
     3841 gccttcactt attcatgcac tgcccagatt tgaagtcctg tccagtttgg tgaacaggtg
     3901 cgccttataa ggaaaacaat gagagaaatc tgggaacaat ttattcattt gctcaagtca
     3961 cgcccccccc caccccccac caaagtaact gaaggaagca cagtctttta tataaacaga
     4021 tgcttcagat gcttttaatt ggacagaaac cccaggggcc acatgttact tttacccttt
     4081 tattatagaa acaaaccttc tcatatgtcc ccttcccact ccacagtcag tgtcaatgag
     4141 cagtggtcat atgctttgga tccaagaaca gttaaaaggg aaaaatacat ttacacagaa
     4201 atagactgtg ttgccaggtc ttagcacttt gctgtcctat aatcacttgt gaccactgcc
     4261 acagccaagt ctatggcaat gaaatcatcg gttagactca gaacagttgg gacttgagtc
     4321 tctattgcag tgcaggccaa gtacatcttc ctgtgtacac agaggtgtca catatacttt
     4381 tgcaaattga gtagcccctt ataagagagc cccctaaggt catctctgtc tctgtcatag
     4441 accatgtatc caaacagtaa gacccaccac tgaagtcttt cctcctagcc ctggaaagct
     4501 cttgctatca caccaccttg gctcggttcc cttatcaatc cgtggctcag taccggcaca
     4561 gcccagcctc actctgactg ctggattcct atatccctca cctcccacat ctcactagac
     4621 tggttcagac caactcaaga gacctttcct cagtttctat cctatgtatc acgctgctag
     4681 gtgctgaata ataacaagat ggatttacaa attaccaata ccccccactc tgtcttttat
     4741 tatctttaag ataacttctg ttcactcact catccactca ctcagtatgt gctgagtatc
     4801 taccctctgt ctgaccctgg gatgcacact aggaatagag ttagcaggca gagcagatgt
     4861 gacatcatga cttcagagca tcctcttttg tttagatttt tgtggtaacc tttccatgcc
     4921 cagagttttt ccacatgcac ctcacacatc cccctggaat taatctttgg aaaacttttg
     4981 gtctctaggg gctatttatt ggctcaggtg taggctttct tcttagggtt tgatattctc
     5041 actttcctca cttgtcttcc aggactctcc acacaacctc tcatgcagca gatccattta
     5101 ctactaccta tacaagcctc ccatgttcca cctctgtgct ttgggtcctg acagtccctc
     5161 tgctgaaatg ccctaccctc tggcctcaat cacccatctc ttaaggccca actccatcag
     5221 ttccgcttga agaatttcca acttattatc atcccccttt cctctaaaaa caaaaacact
     5281 tatcctttct tcccccggag gctagatggg aaaagcatgc tcagaatgcg gaccacattc
     5341 taggaagtaa tgggttttca ttgtgtattt cactgataat ctaaggaggg acctagactc
     5401 tattcccaaa aagtgtgcat atgcaaatat ctgagatttt acatataaat ttaaggattt
     5461 ggaaagtgga attactcttt gattccttag ggggctccac agaccccaga tgaagtcttg
     5521 ttctaaagag tcattaaatg tcactgttgg tgtggttctg gtcgtttaca catccaggga
     5581 ggacagaatt ggaacgagag gtgtgaggag tgagtgatgt ctcttgttat ctacactgag
     5641 taagtgctga gcgacagaga gggggagaaa gaacagctgc ctcacattgt ttaagaaagt
     5701 atctttgttc atacagattt gggattttta tttttatgtt gtgatgttgt gtgtacatat
     5761 ctttgtggat gcatgcacct ttgagggtat acaagccagt atggggaatt ggatcctgcc
     5821 cagctggcaa gacagatgtt tgtgggacct ggttgctagg atttgaattc tggccctcac
     5881 tattgagcag caaacgttct gaaccactca gctgtccctc tagctctgga tttacaattt
     5941 tgaaagctat atagttcctt attgctgtta ttgttattta ttttggccac ttccaaagtt
     6001 gatgtagcaa aatgagttca ggaccaaggg cacgtggttt ctgccctgaa acttaccacc
     6061 tctgagtggg taagcagctg ttttgggact gaaggtggga aagaagtggt tgggtctttt
     6121 tcttttgttg atatttgttt gtttgttttc cttatggaat aacgtctacg caacaagttt
     6181 tcctgtgttc attttttttc atggatcaat tgctggttgt attttcaata aaatggtaat
     6241 gcattatgct ggtagggatc agctcagttt attcttccat taaaaaaaaa ccaacccccc
     6301 tcccccaaaa tcagaactaa gttatcttta gtgctcacga ctaacctaga atccttcctg
     6361 agtgtgccat attgtttgag tagacccagg actatatttc ccactttgaa agctgagctc
     6421 tgccagtcta tctttagccc aaagatcaac tgcttgcgac tctgatgtcc tttgcattta
     6481 tatagtgctt ccagtgaccc gagagaacct gcaggtacac aaggaccctc agagggtgaa
     6541 taggactgaa gttctcttgc ctatagaatg cttacttatg tcatgggtag gacaaataca
     6601 tgtaggacac tttcctcatt ttaattcctt acctgggact taggtttttc actctgtgac
     6661 tttggagact atctcaagtc ctgaagaagt ggttgctgga gccagtgtat accttgccca
     6721 tcagagtaca gttatgggag gtagtgaacg tggcttgagg gaaaaggact caactgtttt
     6781 acagccaata gacagtgtga ccttggccat tctggctttt gcaggagcag agaccttccc
     6841 cagacctaga gtttccaaaa gtcatcttgc tagaccatgg caactatgaa gctctggttt
     6901 caggagaatc atggcttcaa aatgtctaat ttgtgggcac agaaggagtc tttgaaataa
     6961 tgaaacaaat aagtcatgaa tatagtttcc cacctagtcc tgttacagtg ctttgcagtc
     7021 cattctgtgc acagctaatt ccagcattgc ttcctagcac caaaaaacac gactgcccct
     7081 cattacagct ctagctatct taagacaatc tattgactgc caaataatag acatatacat
     7141 ttatcatgag cagttcgttt tacagaaagt agttttgcta actgagtaat tactttccca
     7201 ccctctgtta gcaagcattt atggttattt atttgctttt atcctgcagc tctagattaa
     7261 tgtacacttc atttgccagt aatattttaa tctttttctt tatttagcac ttaagccgtc
     7321 ctctgctctc taaaaaaaaa aatggattta tcttgtaaat taagatgttt gtttcagggc
     7381 taagtagagg aacattcttc catttgtgga gtttaccctt tataattgtt caggatggaa
     7441 gtggtctttc atatttcctt cactcctacc ctttctgaga gatcactctt ggtttattaa
     7501 ccaagcccag tggctagatt ttaattttta attatatttg actttttttt tcttcaataa
     7561 aatgaccgga gagaacattc aaatgtttgg caggtctctg tgtcaccagg aatgacatgt
     7621 ttctgtgact cctgtcaaag tgactttgcc tcaatagtaa gcttcatgag aggatcctgc
     7681 caactgtaaa caggttttac caacggacct gcatgaggtt aaatgacagc tcaggtgtta
     7741 atttggatga tggtttcttc atgatggcag ttgggaaagt aaggttccaa gtcctctttc
     7801 tgtggttctt agcctttcac tgagaacagg agagaaagaa atagcaccaa acactgggat
     7861 tcagacaatg gtgtgctgtg gctgggttgg cgatgtgttg gtcatggaaa ggtttttaga
     7921 taaaggaatg ttataaaaat aatacaaagc ataggcttcc aaatgagaaa cagtctacat
     7981 agtgacagat ttggatgcac acgtggccag tgtggagagt actgaagcaa cattcatctt
     8041 aatctctcac cagagacaca atccctgaac acacagcctt gttcctctct gtctcagtgt
     8101 tcctgcccca atactgtccc attgacccct gggttggcaa tttgcagagg aacttacagg
     8161 tcctggccca gtatgtttgt ttactccttt aaaacaaaca tcctactatc aaaagttatg
     8221 gcacccataa acaatgtaca aagcaattgt attttctttg aaaagttttg aaaaatcttt
     8281 ggagacactc gggtcatcta tatctagaca tttgtccaaa tcattgcatt taatttgtta
     8341 gtagagcttt ctgtgcttgt ctttctgtat ttacttatag taaatgcaga tgcatatgtg
     8401 cagacacagc tatatttgtg catatgtctc tgctgatgta caatgtccac tgtaaagcac
     8461 ctcaggccca ggcattggga agtgtgtgat tcagtagagt tcagggaatg gagacagttg
     8521 cttagatagc acccagaagg ctgcaactga ttagaggagg tatctgtagt tggtgtggca
     8581 agtggacgga cttggagaca tggtttaggt caagttagtt atttactttt atgcaaattg
     8641 gcaataacta gtcaatggct agatggtact tgttctcctt ccttcctact tgagacggga
     8701 tctcgtgtag ctagatctca cttttacaag agctcatttt aattccgttt ttgggaacac
     8761 ccaatctaaa aatgcattga caactcccaa atgttttcac cacactaagg aaaacaagga
     8821 gatcaaggaa aaggaaccca aatttttcaa tacaaaatgc attgctagag aatgtgggga
     8881 catttctgac aggcaagctt tgctaatagc tggtaatcac catctcgcct tgtgtctcca
     8941 aatgtatgga agatgtccgg gtttccccta agacatctga gattgtaaga gcataacact
     9001 ggcatgattt cagcctgcct ttcagctgct tggggctgat ggaggacatg gacctgtatc
     9061 atctggcttg caaacacagt gactagcatc tccctatcga gggccccagt ttggaggatt
     9121 cattcagtgt ttatttctgg agctatgagt tacgttagca cagttactgt tagtagttta
     9181 caagccatac ttccacttgt acacttgatt gtaagataga tttaaattgt gcactatgtt
     9241 gattactcta tataaacgtg gaaattctgt atatttggtc ttatgctata tgtatttgat
     9301 gtgtaaatga taactaacag atatgaaata gtttgctgtg ga
//
