LOCUS       NM_007990                515 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus FAU ubiquitin like and ribosomal protein S30 fusion
            (Fau), transcript variant 1, mRNA.
ACCESSION   NM_007990 XM_489592
VERSION     NM_007990.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 515)
  AUTHORS   Kono,M., Yamasaki,K. and Nakamura,M.
  TITLE     Investigating the regulatory mechanism of glucose metabolism by
            ubiquitin-like protein MNSFbeta
  JOURNAL   Mol Biol Rep 51 (1), 1053 (2024)
   PUBMED   39404900
  REMARK    GeneRIF: Investigating the regulatory mechanism of glucose
            metabolism by ubiquitin-like protein MNSFbeta.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 515)
  AUTHORS   Li,H., Huo,Y., He,X., Yao,L., Zhang,H., Cui,Y., Xiao,H., Xie,W.,
            Zhang,D., Wang,Y., Zhang,S., Tu,H., Cheng,Y., Guo,Y., Cao,X.,
            Zhu,Y., Jiang,T., Guo,X., Qin,Y. and Sha,J.
  TITLE     A male germ-cell-specific ribosome controls male fertility
  JOURNAL   Nature 612 (7941), 725-731 (2022)
   PUBMED   36517592
REFERENCE   3  (bases 1 to 515)
  AUTHORS   Meng,N., Yang,Q., He,Y., Gu,W.W., Gu,Y., Zhen,X.X., Wang,J.,
            Zhang,X., Sun,Z.G. and Wang,J.
  TITLE     Decreased NDRG1 expression is associated with pregnancy loss in
            mice and attenuates the in vitro decidualization of endometrial
            stromal cells
  JOURNAL   Mol Reprod Dev 86 (9), 1210-1223 (2019)
   PUBMED   31339191
REFERENCE   4  (bases 1 to 515)
  AUTHORS   Nakamura,M., Notsu,K. and Nakagawa,M.
  TITLE     Heat shock protein 60 negatively regulates the biological functions
            of ubiquitin-like protein MNSFbeta in macrophages
  JOURNAL   Mol Cell Biochem 456 (1-2), 29-39 (2019)
   PUBMED   30710197
  REMARK    GeneRIF: MALDI-TOF mass spectrometry fingerprinting revealed that
            this MNSFbeta adduct consists of an 8.5 kDa MNSFbeta and heat shock
            protein 60 (HSP60), a mitochondrial protein involved in protein
            folding.
REFERENCE   5  (bases 1 to 515)
  AUTHORS   Notsu,K., Nakagawa,M. and Nakamura,M.
  TITLE     Ubiquitin-like protein MNSFbeta noncovalently binds to molecular
            chaperone HSPA8 and regulates osteoclastogenesis
  JOURNAL   Mol Cell Biochem 421 (1-2), 149-156 (2016)
   PUBMED   27581120
  REMARK    GeneRIF: the association of MNSFbeta with HSPA8 may promote
            RANKL-induced osteoclastogenesis.
REFERENCE   6  (bases 1 to 515)
  AUTHORS   Hiemstra,P.S., van den Barselaar,M.T., Roest,M., Nibbering,P.H. and
            van Furth,R.
  TITLE     Ubiquicidin, a novel murine microbicidal protein present in the
            cytosolic fraction of macrophages
  JOURNAL   J Leukoc Biol 66 (3), 423-428 (1999)
   PUBMED   10496312
REFERENCE   7  (bases 1 to 515)
  AUTHORS   Poirier,C., Poussard,S., Faust,D.M., Imaizumi-Scherrer,T.,
            Weiss,M.C., Ducastaing,A., Montarras,D., Pinset,C. and Guenet,J.L.
  TITLE     Mapping, cloning, cDNA sequence, and expression of the gene
            encoding the mouse micromolar calpain large subunit
  JOURNAL   Mamm Genome 9 (5), 388-389 (1998)
   PUBMED   9545498
REFERENCE   8  (bases 1 to 515)
  AUTHORS   Nakamura,M., Xavier,R.M., Tsunematsu,T. and Tanigawa,Y.
  TITLE     Molecular cloning and characterization of a cDNA encoding
            monoclonal nonspecific suppressor factor
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3463-3467 (1995)
   PUBMED   7724584
REFERENCE   9  (bases 1 to 515)
  AUTHORS   Casteels,D., Poirier,C., Guenet,J.L. and Merregaert,J.
  TITLE     The mouse Fau gene: genomic structure, chromosomal localization,
            and characterization of two retropseudogenes
  JOURNAL   Genomics 25 (1), 291-294 (1995)
   PUBMED   7774934
REFERENCE   10 (bases 1 to 515)
  AUTHORS   Michiels,L., Van der Rauwelaert,E., Van Hasselt,F., Kas,K. and
            Merregaert,J.
  TITLE     fau cDNA encodes a ubiquitin-like-S30 fusion protein and is
            expressed as an antisense sequence in the Finkel-Biskis-Reilly
            murine sarcoma virus
  JOURNAL   Oncogene 8 (9), 2537-2546 (1993)
   PUBMED   8395683
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131692.5.
            
            On Mar 8, 2019 this sequence version replaced NM_007990.3.
            
            Transcript Variant: This variant (1) differs in the 5' UTR,
            compared to variant 3. Variants 1, 2 and 3 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CX763411.1, CX122194.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AC131692.5         95834-95888         c
            56-138              AC131692.5         95510-95592         c
            139-283             AC131692.5         95263-95407         c
            284-339             AC131692.5         94636-94691         c
            340-515             AC131692.5         94311-94486         c
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.34 cM"
     gene            1..515
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /note="FAU ubiquitin like and ribosomal protein S30
                     fusion"
                     /db_xref="GeneID:14109"
                     /db_xref="MGI:MGI:102547"
     exon            1..55
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            56..138
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..465
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /note="ubiquitin-like protein FUBI; MNSF-beta; monoclonal
                     non-specific suppressor factor beta; monoclonal
                     nonspecific suppressor factor betamonoclonal nonspecific
                     suppressor factor beta; 40S ribosomal protein S30; FAU
                     ubiquitin-like and ribosomal protein S30;
                     Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV)
                     ubiquitously expressed (fox derived)"
                     /codon_start=1
                     /product="ubiquitin-like FUBI-ribosomal protein eS30
                     fusion protein"
                     /protein_id="NP_032016.1"
                     /db_xref="CCDS:CCDS29489.1"
                     /db_xref="GeneID:14109"
                     /db_xref="MGI:MGI:102547"
                     /translation="MQLFVRAQELHTLEVTGQETVAQIKDHVASLEGIAPEDQVVLLA
                     GSPLEDEATLGQCGVEALTTLEVAGRMLGGKVHGSLARAGKVRGQTPKVAKQEKKKKK
                     TGRAKRRMQYNRRFVNVVPTFGKKKGPNANS"
     exon            139..283
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            284..339
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /inference="alignment:Splign:2.1.0"
     exon            340..515
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /inference="alignment:Splign:2.1.0"
     regulatory      490..495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /note="hexamer: AATAAA"
     polyA_site      511
                     /gene="Fau"
                     /gene_synonym="MNSFB; MNSFbeta"
                     /note="major polyA site"
ORIGIN      
        1 cttcctcttt cttgactcca tcttcgcggt agcagcagcg gcgtccgcgg gctagtagcc
       61 aacatgcagc tctttgtccg cgcccaggaa ctacacaccc tcgaggtgac cggccaggag
      121 acggtcgccc agatcaaaga tcatgtggcc tccctggaag gcattgcccc cgaagatcaa
      181 gtcgtgcttc tggcaggctc gccgctggag gatgaggcca ccctaggcca gtgtggcgta
      241 gaggccctga ccactctgga agtagcaggc cgcatgctgg gaggtaaagt tcacggttcc
      301 ctggctcggg ctggaaaagt gagaggtcag actcccaagg tggccaaaca ggaaaagaag
      361 aagaagaaga caggccgggc caagaggcga atgcagtaca accggcgctt tgtcaatgtt
      421 gtgcccacct ttgggaagaa gaagggcccc aatgccaatt cctaagtcct attgccaccc
      481 tgccatgcta ataaagccac tgtgtccaga cttct
//
