LOCUS       NP_001074755            4590 aa            linear   ROD 25-DEC-2023
DEFINITION  protocadherin Fat 1 precursor [Mus musculus].
ACCESSION   NP_001074755 XP_006509337 XP_890829
VERSION     NP_001074755.2
DBSOURCE    REFSEQ: accession NM_001081286.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 4590)
  AUTHORS   Zhang N, Shen MY, Meng QL, Sun HP, Fan FY, Yi H and Yang YJ.
  TITLE     FAT1 inhibits AML autophagy and proliferation via downregulating
            ATG4B expression
  JOURNAL   Biochim Biophys Acta Gen Subj 1868 (1), 130519 (2024)
   PUBMED   37952564
  REMARK    GeneRIF: FAT1 inhibits AML autophagy and proliferation via
            downregulating ATG4B expression.
REFERENCE   2  (residues 1 to 4590)
  AUTHORS   Hernandez J, Schaffer J, Herden C, Pflieger FJ, Reiche S, Korber S,
            Kitagawa H, Welter J, Michels S, Culmsee C, Bier J, Sommer N, Kang
            JX, Mayer K, Hecker M and Rummel C.
  TITLE     n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the
            Lung-Brain Axis of Communication in Wild-Type versus Fat-1 Mice
            Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin
            Receptor 23 Knockout
  JOURNAL   Int J Mol Sci 24 (17), 13524 (2023)
   PUBMED   37686333
  REMARK    GeneRIF: n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS
            and the Lung-Brain Axis of Communication in Wild-Type versus Fat-1
            Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin
            Receptor 23 Knockout.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 4590)
  AUTHORS   Li R, Shao J, Jin YJ, Kawase H, Ong YT, Troidl K, Quan Q, Wang L,
            Bonnavion R, Wietelmann A, Helmbacher F, Potente M, Graumann J,
            Wettschureck N and Offermanns S.
  TITLE     Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ
            protein degradation via E3 ligase MIB2
  JOURNAL   Nat Commun 14 (1), 1980 (2023)
   PUBMED   37031213
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 4590)
  AUTHORS   Ringel AR, Szabo Q, Chiariello AM, Chudzik K, Schopflin R, Rothe P,
            Mattei AL, Zehnder T, Harnett D, Laupert V, Bianco S, Hetzel S,
            Glaser J, Phan MHQ, Schindler M, Ibrahim DM, Paliou C, Esposito A,
            Prada-Medina CA, Haas SA, Giere P, Vingron M, Wittler L, Meissner
            A, Nicodemi M, Cavalli G, Bantignies F, Mundlos S and Robson MI.
  TITLE     Repression and 3D-restructuring resolves regulatory conflicts in
            evolutionarily rearranged genomes
  JOURNAL   Cell 185 (20), 3689-3704 (2022)
   PUBMED   36179666
REFERENCE   5  (residues 1 to 4590)
  AUTHORS   Helmbacher F.
  TITLE     Astrocyte-intrinsic and -extrinsic Fat1 activities regulate
            astrocyte development and angiogenesis in the retina
  JOURNAL   Development 149 (2) (2022)
   PUBMED   35050341
  REMARK    GeneRIF: Astrocyte-intrinsic and -extrinsic Fat1 activities
            regulate astrocyte development and angiogenesis in the retina.
REFERENCE   6  (residues 1 to 4590)
  AUTHORS   Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P,
            Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K,
            Pangilinan E, Wakenight P, Tessier-Lavigne M and Skarnes WC.
  TITLE     Functional analysis of secreted and transmembrane proteins critical
            to mouse development
  JOURNAL   Nat Genet 28 (3), 241-249 (2001)
   PUBMED   11431694
REFERENCE   7  (residues 1 to 4590)
  AUTHORS   Cox B, Hadjantonakis AK, Collins JE and Magee AI.
  TITLE     Cloning and expression throughout mouse development of mfat1, a
            homologue of the Drosophila tumour suppressor gene fat
  JOURNAL   Dev Dyn 217 (3), 233-240 (2000)
   PUBMED   10741417
REFERENCE   8  (residues 1 to 4590)
  AUTHORS   Grewal PK, Bolland DJ, Todd LC and Hewitt JE.
  TITLE     High-resolution mapping of mouse chromosome 8 identifies an
            evolutionary chromosomal breakpoint
  JOURNAL   Mamm Genome 9 (8), 603-607 (1998)
   PUBMED   9680377
REFERENCE   9  (residues 1 to 4590)
  AUTHORS   Grewal PK and Hewitt JE.
  TITLE     Fath, the murine homolog of the Drosophila fat tumor suppressor
            gene, maps to chromosome 8
  JOURNAL   Mamm Genome 8 (5), 383-384 (1997)
   PUBMED   9107695
REFERENCE   10 (residues 1 to 4590)
  AUTHORS   Skarnes WC, Moss JE, Hurtley SM and Beddington RS.
  TITLE     Capturing genes encoding membrane and secreted proteins important
            for mouse development
  JOURNAL   Proc Natl Acad Sci U S A 92 (14), 6592-6596 (1995)
   PUBMED   7604039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119214.6 and AC158352.5.
            
            On or before Sep 29, 2023 this sequence version replaced
            XP_006509337.1, NP_001074755.1.
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 24.81 cM"
     Protein         1..4590
                     /product="protocadherin Fat 1 precursor"
                     /note="fat 1 cadherin; FAT tumor suppressor homolog 1"
                     /calculated_mol_wt=503857
     sig_peptide     1..21
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=2429
     Region          39..145
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(46..47,110,112,142,144..145)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          154..253
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(161..162,212,214,250,252..253)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          278..357
                     /region_name="CA_like"
                     /note="Cadherin repeat-like domain; cl46864"
                     /db_xref="CDD:481204"
     Region          372..460
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(379..380,428,430,456,458..459)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          468..566
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(475..476,527,529,562,564..565)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          576..663
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          725..819
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(729..730,782,784,815,817..818)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          827..924
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(834..835,885,887,920,922..923)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          933..1017
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          1044..1136
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1046..1047,1099,1101,1132,1134..1135)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1144..1242
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1151..1152,1205,1207,1238,1240..1241)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1251..1346
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          1364..1454
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1371..1372,1420,1422,1450,1452..1453)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1463..1560
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1469..1470,1523,1525,1556,1558..1559)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1568..1660
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          1673..1763
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1680..1681,1728,1730,1759,1761..1762)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1771..1876
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1778..1779,1838,1840,1873,1875..1876)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          1886..1972
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          1986..2079
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(1992..1993,2042,2044,2075,2077..2078)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2087..2176
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          2189..2281
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2195..2196,2245,2247,2277,2279..2280)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2289..2372
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          2396..2490
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2403..2404,2456,2458,2486,2488..2489)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2498..2594
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2505..2506,2557,2559,2590,2592..2593)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2603..2696
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          2710..2807
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2716..2717,2769,2771,2803,2805..2806)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2815..2915
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2822..2823,2878,2880,2912,2914..2915)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          2924..3021
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(2931..2932,2987,2989,3017,3019..3020)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          3029..3123
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(3036..3037,3088,3090,3119,3121..3122)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          3131..3228
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(3138..3139,3190,3192,3224,3226..3227)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          3236..3333
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(3243..3244,3296,3298,3329,3331..3332)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          3341..3438
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Site            order(3348..3349,3401,3403,3434,3436..3437)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:206637"
     Region          3447..3538
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          3563..3636
                     /region_name="Cadherin_repeat"
                     /note="Cadherin tandem repeat domain; cd11304"
                     /db_xref="CDD:206637"
     Region          3856..3987
                     /region_name="LamG"
                     /note="Laminin G domain; smart00282"
                     /db_xref="CDD:214598"
     Region          4018..4052
                     /region_name="EGF_CA"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; cd00054"
                     /db_xref="CDD:238011"
     Region          4055..4090
                     /region_name="EGF_CA"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; cd00054"
                     /db_xref="CDD:238011"
     Region          4095..4125
                     /region_name="EGF"
                     /note="EGF-like domain; pfam00008"
                     /db_xref="CDD:394967"
     Region          4129..4165
                     /region_name="EGF_CA"
                     /note="Calcium-binding EGF-like domain, present in a large
                     number of membrane-bound and extracellular (mostly animal)
                     proteins. Many of these proteins require calcium for their
                     biological function and calcium-binding sites have been
                     found to be located at the...; cd00054"
                     /db_xref="CDD:238011"
     Site            order(4129,4132,4146)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:238011"
     CDS             1..4590
                     /gene="Fat1"
                     /gene_synonym="2310038E12Rik; Fath; mFat1"
                     /coded_by="NM_001081286.3:369..14141"
                     /db_xref="CCDS:CCDS52547.1"
                     /db_xref="GeneID:14107"
                     /db_xref="MGI:MGI:109168"
ORIGIN      
        1 mgrhltllll lllflqqfgd sdgsqrlept ppiqfthfqy nvtvhensaa ktyvghprkm
       61 giyildpswe irykivsgds enlfkaeeyv lgdfcflrir tkggntailn revrdhytli
      121 vkavekatda earakvrvqv ldtndlrplf sptsysvslp entairtsia rvsatdadig
      181 tngefyysfk drtdvfaihp tsgvvvltgr ldfletqlye leilaadrgm klygssgvss
      241 lakltvhveq anecapiita vtlspseldk dptyaiitve dcdqgangei aslsivagdl
      301 lqqfktvrsf pgskafkvka vgavdwdshp ygynltlqak dkgtppqfsp vkvvhiispq
      361 fragpvkfem dvyraeisef apphtpvvlv kaipsyshlr yvfksapgkp kfglnhntgl
      421 isilepirrq htshfelevt tsdkrasarv vvkvlgtnsn ppeftqtsyk asidenapig
      481 aavtrvsamd pdegengyvt ysianlnhvp fvidhftgtv stsenldyel mprvytlrir
      541 asdwglpyrr evevlatitl nnlndntplf erincegtip rdlgvgeqit tvsaidadel
      601 qlvryqieag neldlfglnp ssgvlslkhs ltdglgakvs fhslritatd genfatplyi
      661 nltvaasrkp vnlqceetgv akmlaekllq anklhsqgdv ediffdsysv nthtpqfgvt
      721 lptgievken lpvganilfm natdldsgfn gklvyaisgg nddscftidm etgvlkvlsp
      781 ldrevmdkyt lnitvydlgi pqraawrlld vtvldandna peflqesyfv evsedkevns
      841 eiiqveatdk dlgpsghvty ailtdtekfs idsmtgvvki iqpldrevqp vhylkieard
      901 qateeprlfs tvllkvsldd vndnpprfip pnysvkvred lpegtiimwl eaydpdvgqs
      961 sqvryslldh geghfdvdkl sgavrivqql dfekkqlynl tvrakdkgkp vslsstcyve
     1021 vevvdvnenl htpvfssfve kgvvkedvpt gssvmtvsah dedtgrdgei rysirdgsgi
     1081 gvfrideetg vietsdrldr estshywltv yatdqgvvpl ssfievyiev edvndnapqt
     1141 sepvyypeim enspkdvsvv qieafdpdss sndkltyrit sgnpqgffsi hpktglittt
     1201 srkldreqqd ehilevtvtd ngvpprstia rvivkilden dnrpqflqkf ykirlperek
     1261 adgdrsaskr eplyrviaad kdegpnaels ysieegnehg rfsiepktgv vsskkfsaag
     1321 eydilsikav dngrpqksst trlhiewisk pkpssepisf eesvfsftvm esdpvahmig
     1381 visveppgmp lwfdiiggny dshfdvdkgt gtiivakpld aeqkssynlt veatdgttti
     1441 ltqvlikvid tndhrpqfst skyevavped tepeveilqi savdrdeknk liytlqssid
     1501 paslkkfrld patgalytae kldheaihqh vltvmvrdqd vpvkrnfari vvnvsdkndh
     1561 apwftspsyd grvyesaavg svvlqvtald kdkgrnaevl ysiesgnign sftidpilgs
     1621 iktareldrs hqvdydlmvk atdkgdppms emtsvriavt vadnaspkft skeysaeise
     1681 airigsfvgm vsahsqssvm yeirdgnmgd afninphsgs iitqraldfe tlpmysltvq
     1741 gtnmaglstn ttvvvhvrde ndnppvftqa eysgfisesa svnsvvltdr nvplviratd
     1801 adresnallv yqivepsvhn yfaidpttga irtvlsldye ethafhftvq vhdmgtprlf
     1861 aeyaanvtvh vidindcppv fskslyevsl llptyrgvnv itvnatdads kafsqvmysi
     1921 tegnigekfs mdhktgtiai qnttqlrsry eltvrasdgr ftsmasvkin vkesresplk
     1981 ftqdaysavv kensteartl avitaignpl neplfyriln pdrrfkisht sgvlsttgip
     2041 fdreqqetfd vvvevtkehe psavahvvvk vtvedqndna pvfvnlpyya vvkvdaevgh
     2101 viryvtaidr dsgrngdihy ylkehhdhfq igpsgdislk kqfehdtlnk eylvtvvakd
     2161 ggspafsaev lvpitvmnka mpvfekafys aeipeniqmh spvvhiqans peglkvfysi
     2221 tdgdpfsqft infntgvvnv iapldfeshp ayklsvratd sltgahaevf vdiivedind
     2281 nppvfvqpsy sttlseasvi gtpvlqvrat dsdsepnrgi syqlignhsk shdhfhidsn
     2341 tglislvral dyeqsqqhri fvravdggmp alssdvvvtv avtdlndnpp lfeqqvyear
     2401 isehaahghf vmcvracdad ssdldkleys ilsgndhksf iidretgiit lsnlrrhtlk
     2461 pfyslnvsvs dgvfrssarv nvtvmggnlh spvfhqneye velaenaplh tlvvqvkasd
     2521 rdsgiyshvt yhivndfakd rfyvndrgqi ftlekldret paekvisirl makdaggkva
     2581 fctvnviltd dndnapqfrs tkyevnigss aakgtsvvkv fasdadegsn advtyaiead
     2641 sesvkenlei nkltglittk esliglenef ftffvravds gsppresvvp vyikilppev
     2701 qlprfsepfy tytisedtpi gteidlirve hggavlyilv kgntpesnrd effvidrqng
     2761 rlkleksldh ettkwyqfsi larctlddye vvasidvsiq vkdandnspv lesspyeafi
     2821 venlpggsrv iqirasdlds gangqvmysl dqsqdadiie sfainmetgw ittlkeldhe
     2881 erasyqikvv asdhgekvql sstaivgvtv tdvndspprf taeiykgtvs eddppggvia
     2941 ilsttdadte einrqvsyfi tggdalgqfa venvqsdwrv yvkkpldreq kdsylltvta
     3001 tdgtfsskar vevkvldand nspvcektsy sdtipedalp gklvmqvsat dadirsnaei
     3061 tytlfgsgae kfklnpdtge lrtlalldre eqavynllvk atdgggrscq aaivltledv
     3121 ndnapeftae pytitvfent epgtpltrvq atdadtglnr kisyslvesa dgqfsiners
     3181 giiqlekhld relqavytlt lkavdqglpr rltatgtvvv svldindnpp vfeyreygas
     3241 vsedivigte vlqvyaasrd ieanaeitya iisgnehgkf sidsktgaif iiesldyess
     3301 heyyltveat dggtpslsdv atvninvtdi ndnspvfsqd tyttvvseda aleqpvitim
     3361 addadgpsns hihysiiegn qgspftidpv rgevkvtkpl dretisgytl tvqaadngnp
     3421 prvntttvni dvsdvndnap lfsrdnysvi iqenkpvgfs vlklvvtdkd sshngppfff
     3481 tivsgndena fevnqhgvll taatikrkvk dhyllhvkva dsgkpqlssm thidirviee
     3541 sihppailpl eifitafgee ysggvigkih atdqdvydtl mysldphmdg lfsvsstggk
     3601 liahrkldig qyllnvsvtd gkfttvadit vhiqqvtqem lnhtvairfa nltpeefvgd
     3661 ywrnfqralr nilgvrkndi qivslqpsep hshldvllfv ersggthvst kqllhkinss
     3721 vtdveeiigv rilevfqklc agldcpwkfc dekvsvdenv msthstarls fvtprhhrta
     3781 vclckdgtcp pvhhgcednp cpagsecvad preekyscvc pgggfgkcpg sssitftgns
     3841 fvkyrllene nrlemklsmr lrtysshavv myargtdysi leihtgrlqy kfdcgsgpgi
     3901 vsvqsiqvnd gqwhavslev egnyaklvld evhtasgtap galktlnldn yvffgghlrq
     3961 qgtkhgrgaq vasgfrgcmd siylngqelp lnnkprayah ieewvdlshg clltatedcs
     4021 sspcqnggvc npsptggyyc kcsalyvgtf cevsvnpcss npclyggtcm vdnggfvcqc
     4081 rglytgqrcq lspyckddpc knggtcfdsl dgavcqcdsg frgercqsdi decagnpcrn
     4141 galcenthgs yhcncsqeyr gkhcedaspn hyvstpwnig laegigiivf iagivllvmv
     4201 fvlcrkmisr kkkrqaeped krlgpttafl qrpyfdskln kniysdippq vpvrpisytp
     4261 sipsdsrnnl drnsfegsai pehpefstfn pesmhghrka vavcsvapnl pppppsnsps
     4321 dsdsiqkpsw dfdydakvvd ldpclskkpl eekpsqpysa reslsevqsl ssfqsescdd
     4381 ngyhwdtsdw mpsvplpdiq efpnyeaide htplysadpn aidtdyypgg ydiesdfppp
     4441 pedfpapdel pplppefsdq fesihpprdm paagslgsss rsrqrfnlnq ylpnfypadm
     4501 sepqkqgage nspcrepytp yppgyqrnfe aptienmpms vyastascsd vsaccevese
     4561 vmmsdyesgd dghfeevtip pldsqqhtev
//
