LOCUS       NM_025850               2000 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus fibronectin type 3 and ankyrin repeat domains 1
            (Fank1), transcript variant 1, mRNA.
ACCESSION   NM_025850
VERSION     NM_025850.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Zhang,J., Zhang,X., Zhang,Y., Zeng,W., Zhao,S. and Liu,M.
  TITLE     Normal spermatogenesis in Fank1 (fibronectin type 3 and ankyrin
            repeat domains 1) mutant mice
  JOURNAL   PeerJ 7, e6827 (2019)
   PUBMED   31086747
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2000)
  AUTHORS   Stauber,M., Weidemann,M., Dittrich-Breiholz,O., Lobschat,K.,
            Alten,L., Mai,M., Beckers,A., Kracht,M. and Gossler,A.
  TITLE     Identification of FOXJ1 effectors during ciliogenesis in the foetal
            respiratory epithelium and embryonic left-right organiser of the
            mouse
  JOURNAL   Dev Biol 423 (2), 170-188 (2017)
   PUBMED   27914912
REFERENCE   3  (bases 1 to 2000)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 2000)
  AUTHORS   Zheng,Z., Zheng,H. and Yan,W.
  TITLE     Fank1 is a testis-specific gene encoding a nuclear protein
            exclusively expressed during the transition from the meiotic to the
            haploid phase of spermatogenesis
  JOURNAL   Gene Expr Patterns 7 (7), 777-783 (2007)
   PUBMED   17604233
  REMARK    GeneRIF: FANK1 may have a role in regulating gene expression in the
            transition from the meiotic phase to the haploid phase during
            spermatogenesis
REFERENCE   5  (bases 1 to 2000)
  AUTHORS   Hwang,K.C., Park,S.Y., Park,S.P., Lim,J.H., Cui,X.S. and Kim,N.H.
  TITLE     Specific maternal transcripts in bovine oocytes and cleavaged
            embryos: identification with novel DDRT-PCR methods
  JOURNAL   Mol Reprod Dev 71 (3), 275-283 (2005)
   PUBMED   15803458
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127348.4 and AC149611.6.
            
            On Mar 23, 2023 this sequence version replaced NM_025850.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY819025.1, BC046278.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               AC127348.4         12815-12920         c
            107-284             AC149611.6         188297-188474
            285-409             AC149611.6         197234-197358
            410-491             AC149611.6         203249-203330
            492-566             AC149611.6         204409-204483
            567-632             AC149611.6         205153-205218
            633-798             AC149611.6         211879-212044
            799-942             AC149611.6         215010-215153
            943-1020            AC149611.6         215403-215480
            1021-1065           AC149611.6         215575-215619
            1066-2000           AC149611.6         215729-216663
FEATURES             Location/Qualifiers
     source          1..2000
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 77.42 cM"
     gene            1..2000
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /note="fibronectin type 3 and ankyrin repeat domains 1"
                     /db_xref="GeneID:66930"
                     /db_xref="MGI:MGI:1914180"
     exon            1..106
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1128
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /note="isoform 1 is encoded by transcript variant 1;
                     fibronectin type 3 and ankyrin repeat domains 1 protein;
                     germ cell-specific 1; GSG1; germ cell-specific gene 1
                     protein"
                     /codon_start=1
                     /product="fibronectin type 3 and ankyrin repeat domains 1
                     protein isoform 1"
                     /protein_id="NP_080126.1"
                     /db_xref="CCDS:CCDS21937.1"
                     /db_xref="GeneID:66930"
                     /db_xref="MGI:MGI:1914180"
                     /translation="MEPHKVVPLSKPHPPVVGKVTHHSIELYWDLEQKEKRQGPQEQW
                     LRFSIEEEDPKMHSYGVIYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSV
                     ATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLV
                     KILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWEARDLGGCTALHWAA
                     DGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGADVNIKDK
                     DGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEEKK
                     KKMPRKSSVH"
     exon            107..284
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            285..409
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            410..491
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            492..566
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            567..632
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            633..798
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            799..942
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1020
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1065
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..2000
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1289..1294
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /note="hexamer: AATACA"
     polyA_site      1307
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /note="major polyA site"
     regulatory      1980..1985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
                     /note="hexamer: AATAAA"
     polyA_site      2000
                     /gene="Fank1"
                     /gene_synonym="1700007B22Rik; FANK1S"
ORIGIN      
        1 gtcagggcaa cccgagcgac gccagacgaa gacaggcgtt aggagggcgg cgccgccagg
       61 gctgggcccg agggcccccg ggagcagctg accatggagc cccacaaagt cgtgccactc
      121 tcaaagccgc atcctcctgt tgtgggcaag gtgactcatc acagcatcga attgtactgg
      181 gatctggaac agaaagagaa acggcaagga ccacaggagc agtggcttcg gttctccatt
      241 gaggaggagg accccaagat gcacagctac ggtgtcattt acacgggtta tgcaacaagg
      301 catgtggttg aaggcctaga accaaggaca ctatacaaat ttcgactgaa ggtcaccagc
      361 ccctctggag aatatgagta cagcccagtc gtctcggtgg ctacgacccg ggagcccata
      421 agtagcgaac actttcatcg tgctgtcagt gtgaacgatg aagatctcct gcttcgaatt
      481 ttggaaggag gccatgtcat gattgacgtg cccaacaaat ttggctttac cgctctcatg
      541 gttgctgctc agaaaggtta caccaggctt gtgaagatcc tagtttccaa tggcacagat
      601 gtgaatctga agaacggaag tggcaaggac agtctcatgc ttgcatgcta cgcggggcac
      661 ctagatgttg tcaaatacct ccggagacac ggagcttctt gggaggctcg agacctcgga
      721 ggctgcacag ctctgcactg ggctgcagat ggaggccatt gctctgtgat tgactggatg
      781 ataaaggacg gttgtgaggt agatgttgta gacactggtt caggatggac gccactcatg
      841 agagtctccg ctgtgacagg aagccagaag gtggcctcac tcctcatcga ggctggggct
      901 gacgtgaaca tcaaggacaa agatggaaag acgcctctca tggtcgctgt cttaaataat
      961 cacgaacagc tagttcagct acttcttgat aaaggggcag atgcaactgt gaaaaatgag
     1021 tttggcaaag gtgtcctaga aatggccaga gtttttgaca gacagaatgt actttcctta
     1081 ctggaagaaa agaaaaaaaa gatgccaagg aagtcctctg tccactgagc agagtgctac
     1141 tcatctgaga gaccgacttg agagaacagc aaactgtgac caccgggctg aacacgtgac
     1201 gtgcagcatc tctgaggacg aggtgtttat ttatttagtt gaagattcac agtgactttt
     1261 atgtaatggg caactcttcc cacattgaaa tacatctttt tacctaagca tgttcatatg
     1321 tggtctcatc actgggcctc cgtagaacag gaatgttttc ttgccctgtg ccttttgcag
     1381 ttagacacaa aaccaaatac ttacgcattg gtgttacata aacgagagtg catgggtccc
     1441 cacccctgtc tccccttccc cttagctgtc ctcgagatgc tccaggcctc ctggcacctt
     1501 ccactcatgt gtttcttatt atctctccca ccccactgca ggccaggctg ctgttgcctc
     1561 ctgcggcggg cggggctcct cctaagcacc caggagttcc ctcttaggct cttggcctca
     1621 catcaaagcc tagaatacat atgtgtaggc tggcgtggtt ctgtttgcag tgtttagttg
     1681 aaggacaggg ctgcgagggc aggtccatcg gttcatgtgt ctgcccatgc tcacctctgt
     1741 ggtgaaagga cccaggccct ggacagcctc cccagtgatt agtgtgttac attgagagta
     1801 gatacgattt ttgaggcaaa tcttataggt tgtagacaaa aaggggttaa gacaccaaga
     1861 ctgtcagtta agagcccaaa gatagaaatg tgggaagttt tagctggacc aagcttaaac
     1921 atcagcagaa acatgtgcat cttgtgtttc cagggacaaa ctggttcatt tagccttcta
     1981 ataaagcagc tagaaaaacc
//
