LOCUS       NM_145946               4621 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus Fanconi anemia, complementation group I (Fanci), mRNA.
ACCESSION   NM_145946
VERSION     NM_145946.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4621)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4621)
  AUTHORS   Yang,Y., Xu,W., Gao,F., Wen,C., Zhao,S., Yu,Y., Jiao,W., Mi,X.,
            Qin,Y., Chen,Z.J. and Zhao,S.
  TITLE     Transcription-replication conflicts in primordial germ cells
            necessitate the Fanconi anemia pathway to safeguard genome
            stability
  JOURNAL   Proc Natl Acad Sci U S A 119 (34), e2203208119 (2022)
   PUBMED   35969748
REFERENCE   3  (bases 1 to 4621)
  AUTHORS   Xu,L., Xu,W., Li,D., Yu,X., Gao,F., Qin,Y., Yang,Y. and Zhao,S.
  TITLE     FANCI plays an essential role in spermatogenesis and regulates
            meiotic histone methylation
  JOURNAL   Cell Death Dis 12 (8), 780 (2021)
   PUBMED   34373449
  REMARK    GeneRIF: FANCI plays an essential role in spermatogenesis and
            regulates meiotic histone methylation.
            Erratum:[Cell Death Dis. 2021 Aug 26;12(9):808. doi:
            10.1038/s41419-021-04096-7.. PMID: 34446697]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4621)
  AUTHORS   Chatla,S., Du,W., Wilson,A.F., Meetei,A.R. and Pang,Q.
  TITLE     Fancd2-deficient hematopoietic stem and progenitor cells depend on
            augmented mitochondrial translation for survival and proliferation
  JOURNAL   Stem Cell Res 40, 101550 (2019)
   PUBMED   31472450
REFERENCE   5  (bases 1 to 4621)
  AUTHORS   Dubois,E.L., Guitton-Sert,L., Beliveau,M., Parmar,K., Chagraoui,J.,
            Vignard,J., Pauty,J., Caron,M.C., Coulombe,Y., Buisson,R.,
            Jacquet,K., Gamblin,C., Gao,Y., Laprise,P., Lebel,M., Sauvageau,G.,
            D d'Andrea,A. and Masson,J.Y.
  TITLE     A Fanci knockout mouse model reveals common and distinct functions
            for FANCI and FANCD2
  JOURNAL   Nucleic Acids Res 47 (14), 7532-7547 (2019)
   PUBMED   31219578
  REMARK    GeneRIF: Studies indicate common and distinct functions of Fanconi
            anemia complementation group I (FANCI) and Fanconi Anemia Group D2
            Protein (FANCD2) during mouse development, meiotic recombination
            and hematopoiesis.
REFERENCE   6  (bases 1 to 4621)
  AUTHORS   Juan,H.C., Lin,Y., Chen,H.R. and Fann,M.J.
  TITLE     Cdk12 is essential for embryonic development and the maintenance of
            genomic stability
  JOURNAL   Cell Death Differ 23 (6), 1038-1048 (2016)
   PUBMED   26658019
REFERENCE   7  (bases 1 to 4621)
  AUTHORS   Joo,W., Xu,G., Persky,N.S., Smogorzewska,A., Rudge,D.G.,
            Buzovetsky,O., Elledge,S.J. and Pavletich,N.P.
  TITLE     Structure of the FANCI-FANCD2 complex: insights into the Fanconi
            anemia DNA repair pathway
  JOURNAL   Science 333 (6040), 312-316 (2011)
   PUBMED   21764741
  REMARK    GeneRIF: crystal structure of FANCI-FANCD2(ID) complex;
            crystallographic electron-density map of FANCI protein bound to
            splayed Y DNA; data suggest ID complex recognizes DNA structures
            resulting from encounter of replication forks with an interstrand
            cross-link
REFERENCE   8  (bases 1 to 4621)
  AUTHORS   Ishiai,M., Kitao,H., Smogorzewska,A., Tomida,J., Kinomura,A.,
            Uchida,E., Saberi,A., Kinoshita,E., Kinoshita-Kikuta,E., Koike,T.,
            Tashiro,S., Elledge,S.J. and Takata,M.
  TITLE     FANCI phosphorylation functions as a molecular switch to turn on
            the Fanconi anemia pathway
  JOURNAL   Nat Struct Mol Biol 15 (11), 1138-1146 (2008)
   PUBMED   18931676
REFERENCE   9  (bases 1 to 4621)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   10 (bases 1 to 4621)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN702700.1, AK085572.1, CN458387.1, CO426844.1, DV655910.1,
            BX519311.1, BY754860.1 and BF021012.1.
            
            On Mar 8, 2007 this sequence version replaced NM_145946.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849383,
                              SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-632               CN702700.1         1-632
            633-1691            AK085572.1         483-1541
            1692-1799           CN458387.1         617-724
            1800-2706           AK085572.1         1650-2556
            2707-3115           CO426844.1         264-672
            3116-3597           DV655910.1         220-701
            3598-4044           BX519311.1         82-528
            4045-4613           BY754860.1         124-692
            4614-4621           BF021012.1         1-8                 c
FEATURES             Location/Qualifiers
     source          1..4621
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.01 cM"
     gene            1..4621
                     /gene="Fanci"
                     /note="Fanconi anemia, complementation group I"
                     /db_xref="GeneID:208836"
                     /db_xref="MGI:MGI:2384790"
     exon            1..54
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            55..157
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..4066
                     /gene="Fanci"
                     /codon_start=1
                     /product="Fanconi anemia group I protein homolog"
                     /protein_id="NP_666058.2"
                     /db_xref="CCDS:CCDS39991.1"
                     /db_xref="GeneID:208836"
                     /db_xref="MGI:MGI:2384790"
                     /translation="MDLKILSLATDKTTDKLQEFLQTLKDDDLASLLQNQAVKGRAVG
                     TLLRAVLKGSPCSEEDGALRRYKIYSCCIQLVESGDLQQDVASEIIGLLMLEVHHFPG
                     PLLVDLASDFVGAVREDRLVNGKSLELLPIILTALATKKEVLACGKGDLNGEEYKRQL
                     IDTLCSVRWPQRYMIQLTSVFKDVCLTPEEMNLVVAKVLTMFSKLNLQEIPPLVYQLL
                     VLSSKGSRRSVLDGIIAFFRELDKQHREEQSSDELSELITAPADELYHVEGTVILHIV
                     FAIKLDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQRFEEQVFDLLKTSV
                     VKSFKDLQLLQGSKFLQTLVPQRTCVSTMILEVVRNSVHSWDHVTQGLIEFGFILMDS
                     YGPKKILDGKAVEIGTSLSKMTNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVT
                     RTSSPINHFLDLFSDIIMYAPLILQNCSKVTETFDYLTFLPLQTVQGLLKAVQPLLKI
                     SMSMRDSLILVLRKAMFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQSIGVTQV
                     RVDVHSRYSAVANETFCLEIIDSLKRSLGQQADIRLMLYDGFYDVLRRNSQLASSIMQ
                     TLFSQLKQFYEPEPDLLPPLKLGACVLTQGSQIFLQEPLDHLLSCIQHCLAWYKSRVV
                     PLQQGDEGEEEEEELYSELDDMLESITVRMIKSELEDFELDKSADFSQNTNVGIKNNI
                     CACLIMGVCEVLMEYNFSISNFSKSKFEEILSLFTCYKKFSDILSEKAGKGKAKMTSK
                     VSDSLLSLKFVSDLLTALFRDSIQSHEESLSVLRSSGEFMHYAVNVTLQKIQQLIRTG
                     HVSGPDGQNPDKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKT
                     FSVVLQFYQPKVQQFLQALDVMGTEEEEAGVTVTQRASFQIRQFQRSLLNLLSSEEDD
                     FNSKEALLLIAVLSTLSRLLEPTSPQFVQMLSWTSKICKEYSQEDASFCKSLMNLFFS
                     LHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHFAVVNLRTAAPTVCLLVLSQA
                     EKVLEEVDWLIAKIKGSANQETLSDKVTPEDASSQAVPPTLLIEKAIVMQLGTLVTFF
                     HELVQTALPSGSCVDTLLKGLSKIYSTLTAFVKYYLQVCQSSRGIPNTVEKLVKLSGS
                     HLTPVCYSFISYVQNKSSDAPKCSEKEKAAVSTTMAKVLRETKPIPNLVFAIEQYEKF
                     LIQLSKKSKVNLMQHMKLSTSRDFKIKGSVLDMVLREDEEDENEEGTASAHTQQDREP
                     AKKRRKKCLS"
     exon            158..230
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            231..361
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            362..518
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            519..576
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            577..618
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            619..742
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            743..828
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            829..955
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1048
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1185
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1366
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1454
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1582
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1653
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1654..1768
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1891
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..1960
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2062
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2239
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..2361
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2526
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2527..2706
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2707..2873
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2874..2950
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..3067
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3119
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3120..3247
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3248..3316
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3317..3425
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3426..3613
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..3667
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3668..3727
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3790
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3791..3886
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3887..3994
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     exon            3995..4619
                     /gene="Fanci"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4602..4607
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fanci"
                     /note="hexamer: AATAAA"
     polyA_site      4619
                     /gene="Fanci"
                     /note="major polyA site"
ORIGIN      
        1 gcggctgcgt ggagtagagc gggaattttg gaaggatccc gagctgaggt tgagttctct
       61 gatatgagca accatggatc tgaaaatttt atctctagca acagataaaa ctacagataa
      121 actgcaggag tttcttcaaa ccctgaaaga tgatgatttg gccagtctcc ttcagaacca
      181 agcggtgaaa ggaagagctg ttggaacgct cctgagagcc gtcctcaaag gctccccctg
      241 ctctgaggaa gatggagccc ttaggagata caagatatat tcttgctgta tccagttggt
      301 tgaatcggga gatttgcagc aagatgtcgc atcagagatc ataggattac taatgctgga
      361 ggtccaccat tttccaggcc cattacttgt tgacttggct agtgactttg tgggtgctgt
      421 ccgagaggac cgcctagtga atggaaaatc tttggagtta ttacccatca tccttactgc
      481 cttggccacc aagaaggaag tcctcgcttg tgggaaaggt gatttgaatg gggaagaata
      541 taagaggcag ttgattgaca ccctgtgttc tgtcagatgg cctcaacggt acatgatcca
      601 gctcacttct gtgttcaagg atgtctgtct aacgccagaa gagatgaatc tcgtggtggc
      661 caaagtgttg acgatgttct caaagttgaa tcttcaagaa attccacctt tggtctatca
      721 gcttctggtt ctctcttcca agggaagcag aaggagtgtt ctggacggaa tcatagcctt
      781 cttcagggag ctggataagc agcacaggga ggaacagagc agcgatgagt tgtcagagct
      841 tattactgcc ccagcagacg aactctatca cgtggaaggc accgttattc tgcacatcgt
      901 atttgccatc aaactggact gtgaattagg cagagaactt ctgaaacact tgaaggctgg
      961 acagcagggg gatcccagta aatgcctatg tcccttcagc atcgctcttc tcctctctct
     1021 cacgagaata cagagatttg aggaacaggt gtttgatctt ttaaagactt ctgttgtaaa
     1081 aagcttcaag gatcttcagc tcctccaagg ctccaagttt cttcagactc tcgtccccca
     1141 gagaacttgt gtttcaacca tgatcttaga agtggtgagg aacagtgttc atagttggga
     1201 tcatgtaact caaggtctga tagaatttgg tttcatcttg atggattcct atgggccaaa
     1261 gaagattctt gatggaaaag ctgttgaaat tggcaccagt ctttctaaaa tgacaaacca
     1321 gcacgcatgt aagctgggag ctaatatctt attggaaacc tttaaaatcc acgagatgat
     1381 cagacaagaa attctggagc aagtcctcaa cagagttgtt acgcgaacat cctctcccat
     1441 caatcatttc ttagacttgt tttcagatat catcatgtat gcacctttaa ttcttcagaa
     1501 ctgttcaaaa gtcacggaaa cttttgacta tttgaccttt ctgcccctcc agaccgtgca
     1561 agggctgctc aaggcggtgc agccgcttct caagatcagc atgtcgatga gagactcctt
     1621 gatcctcgtc ttgcggaaag ctatgtttgc cagccagctg gatgcccgga aatctgcagt
     1681 tgctgggttt ttgctgctcc taaagaactt taaagtccta ggcagcctgc cgtcctcaca
     1741 gtgcacacag tctattggtg tcacgcaggt gcgcgtggac gttcacagcc gatacagcgc
     1801 tgtcgccaac gagaccttct gccttgagat catagacagc ttgaaacgaa gcttagggca
     1861 gcaggcagac atccggctca tgctttacga cggtttctac gatgtccttc gacggaactc
     1921 tcagctggct agttcaatca tgcagactct cttctcacag ttaaaacagt tctatgagcc
     1981 agagcctgat ctgctacctc ctctgaaact aggagcttgt gttctgaccc aaggaagtca
     2041 gatctttcta caagagccgc tggatcatct gctgtcttgc attcagcatt gcttggcctg
     2101 gtataagagc agagtcgtcc ccctgcaaca aggagatgaa ggagaggagg aggaggagga
     2161 gttgtactcc gagctggatg atatgttgga gtccattact gtcagaatga tcaagagtga
     2221 gctggaagac tttgagctgg ataaatcagc agatttctct cagaacacta atgtcggcat
     2281 caagaataat atctgtgcgt gtctcatcat gggagtgtgt gaagttctaa tggaatataa
     2341 tttctccata agtaacttca gcaagagtaa gtttgaggag atcctgagcc tcttcacatg
     2401 ttacaagaag ttctctgaca tcctcagtga gaaagctggc aaaggcaagg ctaagatgac
     2461 cagtaaagtc agcgacagtc tcctgtcctt gaagtttgtg tctgatctcc tcactgctct
     2521 cttcagagac agcatccaga gtcatgaaga gagtctgtct gtcctgcggt ccagcggcga
     2581 gtttatgcac tatgcagtga acgtcacttt gcagaagatt cagcagctaa tacgaacagg
     2641 gcatgtgagt ggccctgatg gtcagaaccc agacaagatc tttcagaacc tctgtgacat
     2701 aactcgggtc ctgctgtgga gatacacatc aattcctaca tccgtggagg agtcggggaa
     2761 gaaggagaag ggaaagagca tctcgctgtt gtgcttggag ggcttgcaga agacgttcag
     2821 tgtggtgctg cagttctacc agcccaaggt ccagcagttt ctccaggctc tggatgtcat
     2881 gggcacagaa gaagaagaag caggtgtcac tgtcactcag agggcctcgt tccagatccg
     2941 gcagtttcag aggtcgttgt tgaatctgct gagcagcgaa gaggacgatt ttaacagtaa
     3001 agaggccctc ctgctcatcg cggtgctgtc caccttgtcc aggctgctgg agcccacctc
     3061 tcctcagttt gtgcagatgt tatcctggac atctaagatt tgcaaggaat acagccagga
     3121 ggatgcctca ttttgcaaga gtttgatgaa cctgttcttc agcctgcatg tcttatataa
     3181 gagtcctgtc accctgcttc gtgacttgtc ccaggatatc catgggcagc tgggagacat
     3241 agatcaagat gtagagattg agaagacaga ccactttgct gtggtgaatt tgagaacggc
     3301 tgcccccact gtctgtttac ttgttctgag tcaggctgag aaagtcctag aagaagtgga
     3361 ctggttaatc gccaagatca agggctcagc aaaccaagaa acgctatcag ataaagtgac
     3421 tccagaagat gcctcttctc aagccgttcc accaactctt ctcattgaga aagctatcgt
     3481 catgcaactg ggaactctgg taacgttctt ccatgagctc gtgcagacag ccctgccatc
     3541 aggcagctgt gtagacactc tactgaaggg cctgtccaag atctacagca ccctaacagc
     3601 attcgtcaaa tattatctcc aggtatgtca gagctccaga ggaattccaa acactgtgga
     3661 aaaactggtg aagctgtcgg gctctcatct gacccccgta tgttactctt tcatttctta
     3721 tgtacaaaat aagagcagtg acgccccaaa gtgctcagaa aaggagaagg ctgcagtgag
     3781 cacaaccatg gccaaagttc ttcgtgaaac caagccaatc cctaaccttg tctttgccat
     3841 tgaacagtat gaaaaatttc ttatccaact gtctaaaaag tccaaggtaa acctgatgca
     3901 gcacatgaag ctgagtactt ctcgggactt caagatcaaa ggcagtgtcc tcgacatggt
     3961 tcttcgagag gatgaggaag acgaaaacga agagggcact gcatcagcac atacacagca
     4021 ggacagagaa ccagccaaga agaggaggaa gaaatgcctg agttaatgtg acctttgggg
     4081 catctgcttc atttgtgccc aacagtaccc cttgtcacac agcctgcact gatgttggtg
     4141 tcctggttct gaacgcactg aattgtgcct tccgttagga ggactttcct gggcaggtcc
     4201 tgctacagaa aaatggctgc cttttgcaaa aaagcacatc tgaaagcctg agtttaggaa
     4261 cctgcaccgc tccaataaag ctccacagga gcaaatacag aacctccaga cagagctagg
     4321 gtccaggctg gcttcgtttt tccaaggagc ctttggtgag ttcaattatc tggtaaatat
     4381 ccagtgcttc acctgtaaga cggtggaaat tggttaggat gcctccagaa ttgtgactga
     4441 actcagaaat gagaatctga atgttggggt caaagacagt gggtgtgagg gagtctttga
     4501 gagtggcagc ttgtcttatt ataacacaag ctttctaacc aactctggca ttttcagcac
     4561 agatacattt tttccacata agaatgcact ttggcttata caataaaact ttaaacatta
     4621 a
//
