LOCUS       NM_133747               2817 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 98, member A (Fam98a),
            transcript variant 1, mRNA.
ACCESSION   NM_133747
VERSION     NM_133747.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2817)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2817)
  AUTHORS   Zhou,J., Wang,R., Zhang,J., Zhu,L., Liu,W., Lu,S., Chen,P., Li,H.,
            Yin,B., Yuan,J., Qiang,B., Shu,P. and Peng,X.
  TITLE     Conserved expression of ultra-conserved noncoding RNA in mammalian
            nervous system
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1860 (12), 1159-1168 (2017)
   PUBMED   29055695
REFERENCE   3  (bases 1 to 2817)
  AUTHORS   Fujiwara,T., Ye,S., Castro-Gomes,T., Winchell,C.G., Andrews,N.W.,
            Voth,D.E., Varughese,K.I., Mackintosh,S.G., Feng,Y., Pavlos,N.,
            Nakamura,T., Manolagas,S.C. and Zhao,H.
  TITLE     PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone
            homeostasis
  JOURNAL   JCI Insight 1 (17), e86330 (2016)
   PUBMED   27777970
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ047600.1, AK167224.1 and BY382397.1.
            
            On Apr 4, 2007 this sequence version replaced NM_133747.1.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is more supported by available transcript
            and homology data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.91922.1, AK146761.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-151               CJ047600.1         3-153
            152-2810            AK167224.1         36-2694
            2811-2817           BY382397.1         442-448
FEATURES             Location/Qualifiers
     source          1..2817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 46.62 cM"
     gene            1..2817
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /note="family with sequence similarity 98, member A"
                     /db_xref="GeneID:72722"
                     /db_xref="MGI:MGI:1919972"
     exon            1..206
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..1701
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM98A"
                     /codon_start=1
                     /product="protein FAM98A isoform 1"
                     /protein_id="NP_598508.2"
                     /db_xref="CCDS:CCDS28974.2"
                     /db_xref="GeneID:72722"
                     /db_xref="MGI:MGI:1919972"
                     /translation="MECDLMETDILESLEDLGYKGPLLDDGALLQAVSAGAASPEFTK
                     LCAWLVSELRVLCKLEENVQATNSPSEAEEFQLEVSGLLGEMNCPYPSLTSGDVTKRL
                     LVEKNCLLLLTYLISELEAARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPA
                     NITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVR
                     RKLLIKRLDVTVQSFGWSDRAKSQTDKLAKVYQPKRSLLSPKGKVSVAHLLAARQDLS
                     KILRTSSGSIREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQAG
                     GRGGGRGGYEHSSYGGRGGHEQGGRGGRGSYDHGGRGGGRGNKHQGGWTDGGSGSGGG
                     YQDGAYRDSGFQPGGYHGGHSGGYQAGGYGGFQTSSYTGSGYQGGGYQQDNRYQDGGH
                     HGERGSGRGGRGGRGGRGGRGSQGGGWGGRGSQTYHQGGQFEQHFQHGGYQYSHSGFG
                     QGRHYTS"
     exon            207..355
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            356..490
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            491..675
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            676..756
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            757..873
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1041
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..2817
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2791..2796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2817
                     /gene="Fam98a"
                     /gene_synonym="2810405J04Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaactgcttg cgcacgctcg gggcatgcgc aatacgggga ctgaggcgcc agctgtcgac
       61 ttggaagttc cggggaagga gcgcatgcgc tagggtacgc gttgccggcg agagggcagc
      121 ctgacgactc ggaaatttga ataccacagt agcatggagt gtgacctcat ggagactgac
      181 atcttggagt cgttggaaga tctaggttac aagggcccat tgttggacga tggtgcactg
      241 ttgcaggcag tctccgctgg agccgcttcc ccggagttta ccaaactctg cgcttggctg
      301 gtgtctgaat taagagtcct ttgtaaacta gaagaaaatg tgcaggcaac taacagtcca
      361 agcgaagctg aagagttcca gcttgaggtg agtgggctac ttggggagat gaactgcccg
      421 tatccttctc tgacatccgg ggatgtaacc aagcgccttc ttgttgagaa gaactgcctc
      481 cttttgctca catacctcat ctcagaacta gaagctgcca gaatgctctg tgtgaatgct
      541 cctccaaaaa aagctcaaga aggaggcggt agtgaggtct ttcaagagtt gaaaggcata
      601 tgtattgctc taggaatgtc caaacctcca gccaatataa ctatgttcca attcttcagc
      661 gggattgaga aaaaattaaa ggaaacatta gcaaaagttc cgcctaatca tgtgggaaag
      721 ccgttactga agaagccgat gggaccagcc cactgggaaa agatagaagc cattaaccaa
      781 gccatagcca atgaatatga agtccggagg aagctgctaa tcaaacgctt ggatgtcacc
      841 gtccagtcct ttggctggtc tgacagagct aagagtcaga cagacaaact agctaaggtt
      901 taccagccga agcgctcact cttgtcgcct aaaggtaagg tctctgttgc tcaccttctg
      961 gccgccagac aagacttgtc aaagatttta aggacaagca gtgggtccat aagagaaaag
     1021 actgcctgtg ccattaataa ggtgctgatg ggcagggtgc ctgacagagg cggcagacct
     1081 aatgaaattg aacctccacc cccagagatg ccaccgtggc agaaaagaca agatggcccc
     1141 cagcagcaag caggaggccg aggcggaggg agaggtggtt atgaacattc ctcatacgga
     1201 ggacgaggag gtcatgaaca aggagggaga ggtggacgtg gtagctatga ccacggtggc
     1261 cgagggggag gaagaggaaa taaacatcaa ggaggctgga cagatggagg gagtggaagt
     1321 ggaggtggtt atcaggacgg tgcttatcga gattcgggct tccagcctgg tggctatcat
     1381 ggtggccaca gtggtggcta ccaagctggt ggctatggtg gtttccagac atcttcatat
     1441 acaggaagtg gctaccaggg cggtggatac cagcaagaca atagatacca agatggtggg
     1501 caccatggtg aacgaggcag tggtcgtggg ggaagaggtg gtcgaggggg tcggggagga
     1561 cgtggaagcc agggaggagg ctggggagga agagggagcc agacttatca tcaagggggc
     1621 cagtttgaac agcacttcca acatggaggc tatcagtata gtcattctgg atttggacaa
     1681 ggaagacatt atactagttg aggctacaga aactcacatt ttgctagagc tcaagtaata
     1741 gaaacttagt ttcagaatcc tgaatccaac atctatttgg aatgaatgta agaccacagg
     1801 tagcaggcat actcctgctt aggataacca tttgctggtc ttcattcaat tctttctctc
     1861 tttttattac taaacagttt tacataacac tgtttattta agaaacatat ctcttctttc
     1921 tatgaaaaac aaattttaaa ggcaatttaa gttgccttta gttgaccggt aaactaatcc
     1981 agttggaaca tacatgcttt tttgaagaaa ttacttgaat aaaatagttt tcacattttc
     2041 aatatgcaag ttttgaaaat gaggatttgc ctggactttt ttatatttaa tgctgggaaa
     2101 ccttcctcat attaacaacc catgtatgtt tttcgtaagc taccttctga tgtctattct
     2161 ccgagcatag ctctgccctg attggcattt tattcagaga gatgtttgtc acctttcttt
     2221 ttggtagacc tgttgggttg gttcctatta catgagctct tttgcagata gcacattcag
     2281 tagccttatc ctgttggtgg aatactgtac catatgctcc tccaaaaccc atgaacacgg
     2341 ccaaaaccca taaaaacaac aaaagcaaac taagtcaaga accgtagtat ctgtaggcac
     2401 ttagttaagt atagcaactc aaaccagacc tgcatccatc cgagacaaac gttcctcctt
     2461 cacccttgtt tttacttgaa attcgctaga agaaatggcg agcagacatc tgttccatgc
     2521 actagttaat gctactggct cagcatatac aagttagctt gctttaggca agggaccttt
     2581 cttgtgatgg acgtgcacta cgaagtgaga tggagtcctg ctccgtgcag gaggcccttc
     2641 attattgctg cagaagacag aagcctggct gagtcactct ccacgtctat cctgaaatca
     2701 ctcaatgctt ctgccgggtt tttgtacatg taaacactgt caagctgtga aagaaagtgg
     2761 ctggaggtgt gtttggtgtg agaggtgagc aataaagtac ctgcacattc tctcctt
//
