LOCUS       NM_145959               5628 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus family with sequence similarity 91, member A1
            (Fam91a1), transcript variant 1, mRNA.
ACCESSION   NM_145959
VERSION     NM_145959.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5628)
  AUTHORS   Nicassio,F., Bianchi,F., Capra,M., Vecchi,M., Confalonieri,S.,
            Bianchi,M., Pajalunga,D., Crescenzi,M., Bonapace,I.M. and Di
            Fiore,P.P.
  TITLE     A cancer-specific transcriptional signature in human neoplasia
  JOURNAL   J Clin Invest 115 (11), 3015-3025 (2005)
   PUBMED   16224537
REFERENCE   2  (bases 1 to 5628)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   3  (bases 1 to 5628)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 5628)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107742.10.
            
            On Jan 20, 2023 this sequence version replaced NM_145959.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122297.1, BC070426.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-312               AC107742.10        121550-121861
            313-397             AC107742.10        126283-126367
            398-549             AC107742.10        127830-127981
            550-607             AC107742.10        129405-129462
            608-675             AC107742.10        130281-130348
            676-789             AC107742.10        130861-130974
            790-880             AC107742.10        132678-132768
            881-943             AC107742.10        133138-133200
            944-1050            AC107742.10        136076-136182
            1051-1089           AC107742.10        136263-136301
            1090-1202           AC107742.10        136746-136858
            1203-1318           AC107742.10        137290-137405
            1319-1431           AC107742.10        138599-138711
            1432-1518           AC107742.10        138978-139064
            1519-1651           AC107742.10        140748-140880
            1652-1800           AC107742.10        147662-147810
            1801-1935           AC107742.10        148916-149050
            1936-2049           AC107742.10        149245-149358
            2050-2122           AC107742.10        153670-153742
            2123-2272           AC107742.10        154427-154576
            2273-2377           AC107742.10        156015-156119
            2378-2501           AC107742.10        156622-156745
            2502-2571           AC107742.10        159067-159136
            2572-5628           AC107742.10        160834-163890
FEATURES             Location/Qualifiers
     source          1..5628
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 24.76 cM"
     gene            1..5628
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /note="family with sequence similarity 91, member A1"
                     /db_xref="GeneID:210998"
                     /db_xref="MGI:MGI:1277178"
     exon            1..312
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..2754
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /note="isoform 1 is encoded by transcript variant 1;
                     skeletal muscle cells re-entry induced; protein FAM91A1"
                     /codon_start=1
                     /product="protein FAM91A1 isoform 1"
                     /protein_id="NP_666071.2"
                     /db_xref="CCDS:CCDS37080.1"
                     /db_xref="GeneID:210998"
                     /db_xref="MGI:MGI:1277178"
                     /translation="MNIDVEFHIRHNYPWSKLPTNVKQSLGNSQREYEKQVVLYSIRN
                     QLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYAGIM
                     EDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPMK
                     PVEIAIEAWWVVQAGYITEDDIKICTFPEKGAIDKIIDSGPQLSGSLDYNVVHSLYNK
                     GFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLE
                     IDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWD
                     GGESRSPVQEASSATDTDTNSQEDPADTASVSSLSLSTGYTKRIAFLFDSTLTAFLMM
                     GNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTIL
                     FLRHNKDLVAQTSQPDQPNYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLT
                     NEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHVTGQGPPSLLLSKGTRLRKLPDIFQG
                     YDRLLITSWGHDPGVVPASNVLTMLNDALTHSAVLIQGHGLHGVGETVHIPFPFDEAE
                     LQGEFTRASMGVHKALQILRSRVDLQHFCGYVTMLNASSQLASRKLSEASDERGEPDL
                     ASSSDVNGSTESFEMVIEEASTDLATKPNSGATAEADWVPLELCFGIPLFSSELNRKV
                     CQKIATHGLCRKESLQSLLHSSRKLSLQVLNFVHSFQEGAATLDLHAEPGFSSVLSQS
                     PCADMGVPLPAKNLMFKDGVLSEWSGRSPSSLLIASLHL"
     exon            313..397
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            398..549
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            550..607
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            608..675
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            676..789
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            790..880
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            881..943
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1050
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1089
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1202
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1318
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1431
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1518
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1651
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1800
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..1935
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2049
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2122
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2123..2272
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2377
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2501
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2502..2571
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..5628
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5542..5547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /note="hexamer: AATAAA"
     polyA_site      5565
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /note="major polyA site"
     regulatory      5604..5609
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
                     /note="hexamer: ATTAAA"
     polyA_site      5628
                     /gene="Fam91a1"
                     /gene_synonym="D15Ertd621e; mKIAA0493; SKIN"
ORIGIN      
        1 acagagccat ttccggcagg ccgaaactag gaagaaactt ggagctgccg aggcgcgggt
       61 cgtagttggc gctcccgtcc gtgccccgtg gccggcgccg cgcggacctg tgggggcctg
      121 gccatggggc ggcgccgtgc tcgtgcggcc tagacgtgcg ggctccgctg acaggccggg
      181 cgctcgcggg cggcaggcgg cgtggcagcc gcggccgccg cgggcctggg ctccggcatc
      241 atgaacatcg acgttgagtt ccacatccgg cacaattatc cttggagcaa gttgccaacg
      301 aacgtgaagc agagtcttgg aaactcacag agagaatatg aaaagcaggt tgttttgtac
      361 agtattcgca atcagttgcg ctacagaaat aacctagtta aacatgtcaa gaaagatgaa
      421 cgcaagtact atgaggagct gctcaagtac agtcgtgacc atctcatgct gtacccttac
      481 cacttatccg acatcatggt caagggcctg aggataaccc cattctcata ctatgctggg
      541 atcatggagg acatcatgaa cagtgagaaa agttacgatt cattgcctaa ttttactgct
      601 gctgactgtc tgcgacttct tggcatagga aggaaccagt acattgacct gatgaatcag
      661 tgcagatctt caaaaaaatt cttcagaagg aaaactgccc gtgaccttct accaatgaag
      721 ccagtggaaa ttgccatcga ggcgtggtgg gtggtgcagg ctggctatat cacagaagat
      781 gacatcaaga tatgcacttt tcctgagaaa ggcgccattg ataagatcat cgactcaggt
      841 cctcagctct ctgggtcact agattacaat gtcgtacaca gtttgtataa caaaggcttt
      901 atttatctgg atgtgcccat atcagatgac agttgtatag ctgtcccccc tctggaaggc
      961 tttgtaatga atcgggtaca aggtgattat tttgaaaccc tactctataa gatatttgtg
     1021 tctatagatg aacacactaa tgttgcagag cttgcaaatg tccttgagat agacttatcg
     1081 ctggtgaaga atgctgtttc aatgtattgc cgattgggct ttgcccataa gaagggacaa
     1141 gtgataaatt tggatcaact tcattcgtca tggaagaatg ttccatctgt gaatagacta
     1201 aagagcacat tagacccaca aaagatgctc ttatcgtggg atggcgggga gagtaggagt
     1261 cccgtgcaag aagcctcttc tgctactgac acagacacaa atagtcaaga ggatccagct
     1321 gacacggcca gtgtgagcag tttgagtctg tccactgggt acacaaagcg aattgcattc
     1381 ctgtttgact ccactctgac tgcattctta atgatgggaa acctttcacc gaacttgaaa
     1441 agccacgcag tcaccatgtt tgaagtaggc aaactctcag atgagtctct ggacagcttc
     1501 cttatagaat tagagaaggt tcagagcact ggtgaaggag aagcacagag atactttgac
     1561 cacgcactta ctctgaggaa cactatcctc ttcctgcgtc ataataagga tctggtggct
     1621 cagacctctc agccagacca gcccaactat ggtttccccc tggatctctt acgctgcgaa
     1681 agccttcttg gtttggaccc agcaacttgc agcagagttc taaacaaaaa ctacacactg
     1741 cttgtttcca tggcgcctct taccaatgag atccggccag tcagcagctg caccccgcag
     1801 catatcggac cagctatccc agaagtcagt tctgtctggt ttaaattgta tatttaccat
     1861 gtcactgggc aaggaccacc atctctctta ctgtccaaag gtacaagact tcggaaactg
     1921 ccagatatat tccagggtta tgatcggtta cttataacct cttggggcca tgaccctggg
     1981 gtcgttcctg cttcaaacgt tctcacgatg ctgaatgatg ctttaaccca ctcagcagtg
     2041 ctcattcagg gacatggttt gcatggggta ggagagactg tccatatacc ctttccattt
     2101 gatgaagcag agctgcaagg agagttcacc cgtgccagta tgggtgttca taaagcactg
     2161 cagattctgc ggagcagagt ggacttgcag catttctgcg gctatgtcac catgttgaat
     2221 gcttctagcc agcttgcaag taggaagctc agtgaggctt ctgatgagag aggcgagcct
     2281 gatttggctt ctagttcaga tgtaaatggg agcacagagt cgtttgaaat ggtcattgag
     2341 gaagcaagta cagatttggc gacaaaacca aactctgggg ccacagcaga agcagattgg
     2401 gttcctcttg agctgtgttt tggaattcct ttgttcagtt ccgaattaaa ccggaaagtt
     2461 tgtcagaaaa tagctaccca tggcctgtgc aggaaagaga gccttcaaag tctcttacat
     2521 tccagtagaa aactctccct gcaagtcctt aactttgttc attcattcca ggaaggtgct
     2581 gctactctgg atctccacgc ggagcctggc ttctcaagtg tgctttcaca gtcgccctgc
     2641 gctgacatgg gagttccact tccggccaaa aacttaatgt ttaaagatgg tgtcttatca
     2701 gagtggagcg gacgctcacc ttcctccctg ctcatcgcta gtctccattt gtagtaattt
     2761 gattacagca tttattgctc acactttctg ccttttttct ttcttacgct ggcttcacag
     2821 tgtcagccac taagcttcca gctaccttgg tgcaggtcaa gcttcactgg taggaaccaa
     2881 ctgctcggaa tgtgctcgtg ttttctgaag cccgaggcct gtcgttacac atcttactgc
     2941 aaccaagtac tgctcagcag ccagcactgc actggagaca atctgcattt cttttataaa
     3001 actgaggaca cactttatag gctgtagatg actgttacgt ttataagcag tcactatgaa
     3061 tattgcagtg gtagttttat atgtaagttt ctcagacata aacctggttt aattttatat
     3121 tttgttacct acactgaggg aatcatggga ggagatggac tcttcttcct ccaaaaggct
     3181 tcttggttct tgaggcagtc acgctagaag tggcaagcat ccagcagtga ggggtacaga
     3241 ccagggcatt aaggattact gtggacgtca gtaaattatg tacgccgagt gaacatgatt
     3301 gagggtatgt cggtcagcat agttacataa acctcacctt gatttctacg gtcttaactg
     3361 atgatccttt gacatctcat gagcgctatg gagaacattc tatttttaaa tgatgtttgt
     3421 atgtggactc ccgttgtcac tcacctttgg ctttatattt tcatagagtc tttatggaaa
     3481 aatagaattt attttccacg tgtagttgag gctgttgcac gtctcatctt gtagctttac
     3541 ctaggaactg ttagggtaat tgaccttgat ttcaactaag gattgtggtg gaagttggaa
     3601 tcgcacagca gcagcctcag ggccgtgtct tggactcagc tccatgatga aacgattcct
     3661 cagacacaac atctggacct gaaactggca cacagctctg gggagtgaag aggcactgac
     3721 tggcttcgtg tgctgtgggc attgggtctt ttagtgtctc aaatgtcaga atctttggat
     3781 ttgccactta ggctgtccag gtcaccttcc ctggggtgtt tgtgtgctta gttgagctcc
     3841 cctaactgaa ttgggcaagc gacagacctg aaacacgcaa gcattacact gattgagaac
     3901 attggagcct aacagctttg ctgatggctt ttgttattta tacaagtgat atttgtgtaa
     3961 ttaacagact tctgcaagta tatgcctttc ttgaaaccgt taaagtggcc atgcatttaa
     4021 taccatggcc tatctgtaga attgactatt ttggaccagg ttacctgtgg cacagttagt
     4081 gctgtgtttg ggtaaatgaa gtaatgttta gttttctact ttgtcttgta taaggtagaa
     4141 ctgtatgtat gtcatgtttg tctgtaaaag gaaaagtaca tagtaatatt aaaataattt
     4201 ctatgactgt gaattactca tttatttttc caattactga gactgtacat tcctagtgct
     4261 attagttata tgtgtatgta acttttacag tttcaactga aagttgtccg tatttctttt
     4321 gatcagggct cttaatctca tttgctttga ttgagttaac tgtaggtatt tatctttgta
     4381 ttagtagtcg aataccaact ctaatgacat gtacactaat aaagaattga acagttgtag
     4441 ttacgacagt ccagttattg ctgagtttaa agcttaaaat atgggagtga tttgctgcta
     4501 taattccttt gagaaacact gaagaagaga tgagacctaa ccgtgatcat gaacttcagg
     4561 gacagtactt taaattagaa caacacttta cacctctctg atttttgttt agtaggaaga
     4621 ttgaaaccat cagaatccca gccgaagtcc ctgtcttctg aggaaccctg ttcattttag
     4681 agaggatgac gtgtgtttgt gctttgcttt atgactgtct ggttccttcc actcacgtta
     4741 gctctcgcag aggcctctat taagttgata aaaaataaat aaaaaaataa ctatagactt
     4801 tgttctttgc caaagaagat tgataaaagt tgtgcccagt tattttgcaa atgtttaatt
     4861 tcatctggct tagcaccact ctctctcacc acttattata acttgaacca tgacatttag
     4921 aagccaagaa aaaaagagct actaaatatc aaaaagggcg tacagtttag taaaggtcta
     4981 gtttcgactc acaaatgtgt ctaaagaaat gcaactttgt atcacttaag aagttaggct
     5041 cagccattcc tttcagtagc cgttctcacc ctgtgggttg caaccccttt gggggctcag
     5101 atccatcctt tcacagggtc atatatcaga tatcctgcat atcagatatt tattattatt
     5161 cataacagca aaacaacagt tacaaagtag taaaaaacaa ttgtggttgg ggatcgctgt
     5221 gccatgagga actgtgttga agggtcacag catcaggaag gctgagaacc actgccttag
     5281 ccctctcttg tgtaacatgt gtaaccagat gcttttgcat ttgtttgagg gatgtgattt
     5341 ccctttctgg gtcgtttgct ttctctgcca ttctcatttt ttatgttcag tgtttcaagt
     5401 acactttgta ttaaaggatt ttaaagtacc aaaactgtaa ctcagtacaa tggattgtgt
     5461 tctgttatga tgttaatatt atccaaggaa attgtataaa gtgttgtcaa tttgattatt
     5521 gacacaaata acatgtttac aaataaactg gtgttgatca agttactgtg gagagtgtct
     5581 aattttctgg gacttgtttt aatattaaat acctgtgctt ttcaaaaa
//
