LOCUS       NM_178618               4786 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus family with sequence similarity 83, member G (Fam83g),
            mRNA.
ACCESSION   NM_178618
VERSION     NM_178618.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4786)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4786)
  AUTHORS   Liu,C., Huang,X.Y. and Huang,Y.
  TITLE     FAM83G promotes proliferation, invasion, and metastasis by
            regulating PI3K/AKT signaling in hepatocellular carcinoma cells
  JOURNAL   Biochem Biophys Res Commun 567, 63-71 (2021)
   PUBMED   34144502
  REMARK    GeneRIF: FAM83G promotes proliferation, invasion, and metastasis by
            regulating PI3K/AKT signaling in hepatocellular carcinoma cells.
REFERENCE   3  (bases 1 to 4786)
  AUTHORS   Balmer,P., Fellay,A.K., Sayar,B.S., Hariton,W.V.J., Wiener,D.J.,
            Galichet,A., Muller,E.J. and Roosje,P.J.
  TITLE     FAM83G/Fam83g genetic variants affect canine and murine hair
            formation
  JOURNAL   Exp Dermatol 28 (4), 350-354 (2019)
   PUBMED   29963719
  REMARK    GeneRIF: In this study, we demonstrate that FAM83G/Fam83g is
            associated with hair morphogenesis, differentiation and cycling and
            provide first insights into functional consequences of
            FAM83G/Fam83g variants.
REFERENCE   4  (bases 1 to 4786)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   5  (bases 1 to 4786)
  AUTHORS   Radden,L.A. 2nd, Child,K.M., Adkins,E.B., Spacek,D.V.,
            Feliciano,A.M. and King,T.R.
  TITLE     The wooly mutation (wly) on mouse chromosome 11 is associated with
            a genetic defect in Fam83g
  JOURNAL   BMC Res Notes 6, 189 (2013)
   PUBMED   23656696
  REMARK    GeneRIF: suggest that this mutation in Fam83g is the likely basis
            of the mouse wooly phenotype
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY062936.1, BC085279.1, AK009716.1 and BX631674.1.
            
            On Nov 9, 2006 this sequence version replaced NM_178618.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085279.1, AK028566.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               BY062936.1         3-179
            178-2319            BC085279.1         139-2280
            2320-2523           AK009716.1         459-662
            2524-2938           BC085279.1         2485-2899
            2939-4588           AK009716.1         1078-2727
            4589-4786           BX631674.1         4-201               c
FEATURES             Location/Qualifiers
     source          1..4786
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.96 cM"
     gene            1..4786
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /note="family with sequence similarity 83, member G"
                     /db_xref="GeneID:69640"
                     /db_xref="MGI:MGI:1916890"
     exon            1..646
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..2563
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /codon_start=1
                     /product="protein FAM83G"
                     /protein_id="NP_848733.2"
                     /db_xref="CCDS:CCDS36175.1"
                     /db_xref="GeneID:69640"
                     /db_xref="MGI:MGI:1916890"
                     /translation="MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRD
                     AFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRPEPQDNGGADASEET
                     SAAGGPPATETLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPH
                     IKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHM
                     CERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWS
                     AARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPL
                     VPTGTMAKKLVNPKYALVKAKSVDEIAKSSSDKQEVTRPPGLRGPAVAERPGDLSELL
                     PPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPNQMNRIKIR
                     DTAHASAQHQLWKQSQGARPCPAPCPPPAPRDSQGVVPAENGFPQGNPEPQAPVPKPR
                     TVPVASVLARDGSDIGWALDTPEKETPQNGIDPRLPSTASESEVPQQQHSSMTQDDPD
                     GLERGLPNGLDEDEDDDDDYVTLSDQDSLSGSSGPGPGHRRPSVASSMSDEYFEVRER
                     SVPLQRRHSEQMANGPGHPPRRQLSAPHVTRGTFGGPLSSPLWAQGRSREDVDASRIQ
                     GQRPMDRQAQGQHFHRHGSTTSRTPGPPRFRPAADGTQSSSKKASPAAAGPHHWQPKG
                     SPTPRMLPDPGSPRPTRNTRLRAELRATEEHASPFGIPYSKLSQSKHLKARAGGSQWA
                     PSDSKRRARDHKEP"
     exon            647..814
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /inference="alignment:Splign:2.1.0"
     exon            815..939
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /inference="alignment:Splign:2.1.0"
     exon            940..2200
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /inference="alignment:Splign:2.1.0"
     exon            2201..4786
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3025..3030
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /note="hexamer: ATTAAA"
     polyA_site      3048
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /note="major polyA site"
     regulatory      4755..4760
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /note="hexamer: AATAAA"
     polyA_site      4786
                     /gene="Fam83g"
                     /gene_synonym="2310040C09Rik; wly"
                     /note="major polyA site"
ORIGIN      
        1 ccgccctctg accccgaccg cggtcttttg ctgattccct caggtgcggt tctcagaggc
       61 gccgaggccc cggagcctga gagcgcggtg cccgtcgggc cgcgttccca cagcgagggc
      121 caccatggcc ttctcccagg tgcagtgtct ggacgacaac cacgtgaact ggcgatccag
      181 cgagtcgaag cccgagttct tctacagcga ggagcagagg ctggccctgg aggccctggt
      241 ggcccggggt cgcgacgcct tctacgaggt gctgaagcgc gagaacatcc gcgactttct
      301 ttcggagctg gagctttcgc gtatcgtgga ggccatcgag gtgtacgacc cgggctctga
      361 ggacccgcgg gtctcgggcc gccgccccga accccaggac aacggaggcg cggatgccag
      421 cgaggagacc agtgcggcgg gcgggccccc agccacggag acgctgccct cgctggagta
      481 ttggccccag aagtcggacc gctccatccc gcagctggac ctgggctggc ctgacaccat
      541 tgcctaccga ggtgtgaccc gggccagcgt ctacatgcag ccacccatcg acgggcagcc
      601 gcacatcaag gaagtggtgc gcaagatggt cagccaggcg cagaaggtga tagctgtggt
      661 catggacatg ttcactgacg tggacatctt caaggacctg ctggatgctg gcttcaagag
      721 gaaggtggct gtgtacatca ttgtggatga gagtaatgtc aagtatttcc tgcacatgtg
      781 tgagcgggcc cgcatgcacc tggggcacct caagaatctc agggtacgca gcagcggggg
      841 aaccgagttc ttcacacgat cagccaccaa gttcaagggt gtcctggccc agaagttcat
      901 gtttgtggat ggagatcggg ccgtgtgtgg ctcctacagc ttcacatggt cagctgcaag
      961 gaccgatcgg aatgtgatct ctgtgctgtc tggtcaggta gtagagatgt ttgatcgaca
     1021 gttccaggag ctgtacctta tgtctcagag tgtcagcctc aaggacatcc ccatggagaa
     1081 ggagccagag ccagagccca ttgtgctacc atctgtggta cccctggtac ccacaggcac
     1141 catggccaag aagcttgtca accccaagta tgcacttgtc aaggccaaga gtgtggatga
     1201 gattgccaag agttcctctg acaaacagga ggttacgaga ccccctgggc tgcggggccc
     1261 tgcagtggct gagcgccccg gggatctttc tgagctgcta ccacctgtcc acccagggct
     1321 gctcaacctg gagagggcca atatgtttga gtacttgccc acatgggtgg agccagatcc
     1381 agagcctggc agtgacatcc tgggctacat caacatcatt gatcccaaca tctggaaccc
     1441 ccagcccaac cagatgaacc gcatcaagat ccgtgacaca gcccatgcca gtgcccagca
     1501 ccagctgtgg aagcagagcc agggggcccg accctgccca gcaccctgcc ctcccccagc
     1561 acccagggac tcccagggtg tggtcccagc tgagaatggc ttcccccagg ggaaccctga
     1621 accacaggct cctgtaccta agccccggac agtccctgtg gcaagtgtac ttgcccggga
     1681 tggtagtgat attggctggg ccctggatac cccagaaaag gagacacccc aaaatgggat
     1741 agaccccagg ctaccaagca cagccagcga aagcgaggtc ccacaacagc agcactcatc
     1801 tatgacgcag gatgaccctg atggcctgga gagaggactc cccaatgggc tggatgagga
     1861 tgaggatgac gacgatgact acgtgaccct cagtgaccag gacagcctct caggcagttc
     1921 tggccctggc cctggccacc ggcgaccctc agtggcttca tccatgtcag acgagtactt
     1981 tgaggtgagg gaacgatcag tacctctcca gaggcgccac tcagagcaga tggccaatgg
     2041 gccaggccac ccaccccgac gacagctcag tgcccctcat gtaaccagag gaacctttgg
     2101 tggccccctg agtagccccc tgtgggccca gggtcggagc agagaagatg tagatgcatc
     2161 aaggatacag ggacaacgcc ccatggacag gcaggctcag ggccagcatt tccaccgaca
     2221 tggaagtact acctcaagga ccccagggcc tccccgtttc cggcctgctg ctgatggtac
     2281 ccagagctct tccaagaaag caagcccagc cgcagcaggc ccccaccact ggcagcccaa
     2341 ggggagccca acacccagaa tgctaccaga tcctgggagc ccaaggccaa cccgaaacac
     2401 tcgcctccga gcagagctca gggccactga ggaacatgcc agtcccttcg gaatcccata
     2461 ctccaaattg tctcaatcga agcacctaaa ggccagggca ggtggcagcc agtgggcccc
     2521 ttcggactct aagcgcaggg cccgagacca caaggaaccc tagcagccta gatggaccca
     2581 accccgcccc agagggcagc aggtgggggt gggcaatgtt ggcgctcacc tggtcagtgc
     2641 accagtacca ggtggccatg atggtcagac caaaggtcat cccagtccac gggaggtctc
     2701 ctgtggaagg gtcccggaac atatgcatgg cgtctgctcg cggcaggtgg caggtggtgt
     2761 tggggatggt cctggagggg atggcctggg catacgccgc ctccagctgc tcataaccac
     2821 cgatctggtt gaaagctgga gggtggggca gagtgggttg gttctgggtg gtcctgactc
     2881 ccaggatcct cctaccctca tctcacagat aacttcatgc atcaaactgg aacccctacc
     2941 tcatatttcc tgctccagga aggttgaggt tgaaaaaaaa gaaaaagagt gaaatagagt
     3001 attttatttg tatttaaaat aactattaaa tgagcatttt gcacatgggc ccacagtgtc
     3061 ctgttggcca gcggggttca cggctagtgt ctggaagcct gctggcctcg ggtatgggct
     3121 tctctgccag tctctggact ggcccttcaa ggaggtggaa gtggttttct ctgtgtttga
     3181 gtcattgagt attgaagcca tgacctggac ttctgaaggc tgtgacttca ctagagctaa
     3241 gacactgctg gcattgtggc cccatccttc caagacacag ggaaggaagg cagaggctcc
     3301 tcagggcctt atggtaggcc tagcaggtag agctcaggcc aggggtcttt cctctgagtc
     3361 gggaacatgt ccattctacc tcagggttgg gtggtgcgag gccaagccag gcctggctgt
     3421 gtctgtagtc atttgccctc tcattcggcc tatatctgac cattaggtcc ctccccttca
     3481 gtaggtcctg gagacatagg ggctgctacc aggggaggaa cacacctggg tgtggggcag
     3541 cttctggcat cttcccaggc cccctttccc agccgggtgt ggagctaggt aggctagggt
     3601 ctgtttcacc aggaatctct cctgaggccc agtggcagcc tctgtcacag ggtcccagag
     3661 cctgagctga ggcgtcaccc ttaaagccac ccaccttgag acctatcctt gctccctcct
     3721 tccctcctgt ttccctccca gggcatgagt agaactccct tgtctgtttc taaactcgtg
     3781 ttaccagtcc agtgtacctc cctccctgca ggcttttgtc tggcaggaga cagcaacacc
     3841 tcctaggact ctgtacttga ttttaagcac tggaggaaac acctcagcag ttttgtggtc
     3901 tgctaattgt gtgctgcaca cacagctgcc tgctctaggg cctgcccagc cctgagggag
     3961 gctagtcagc gcctccctac tgcgcccctg taggcaggag gaagcagccc atcagcctag
     4021 gaagccaaca gcagggcagg tcaactgtag cttaaccttt agagctcttc aaggtgcagg
     4081 gactgcctgc ccaggcccca gccccagacc tcacctttga ctgccaaaat gacagcaccc
     4141 accaccatga tgattgtctg cagggcatct gtgtatatca cagtggccag gccccctgca
     4201 agaaacaagg ctgctggagt aagtgtccca ggagagtctg acctcatcac cagagctgct
     4261 ggtggggcct cattccttgc agcagatggg tgagctgcac caaagtacct gagcagttag
     4321 gccccaggtc cccacctgac cacctgtgaa ctggccatca tcaggctccc agtttctcct
     4381 gtacaaatcc ctggctcctc gtgggtcctc gggacccgta ccatacctgc aatggtgtac
     4441 agggccgtaa tggcgagcgt gaggatggtg gacaggtaga agttccagcc caggcagatg
     4501 tggacaaaca gggctcctgc gtacaggtca atctagggaa agcagagttg ggcagaagtc
     4561 agacattacg gtgagattca gggctcagag tgggggtgct gtactcactg gctttgtgac
     4621 ctggcctggg gggggttcca ggtaagagaa acagagaccc ctaccccagc tgtttactac
     4681 ctggtgggct ggttgaggat gggagagagt tggctgtgtg ccatgttcag atgtatggtg
     4741 gatgttactg tcacaataaa gttcaaagtg gccagtgccc atcaga
//
