LOCUS       NM_027975               2268 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 83, member D (Fam83d),
            transcript variant 1, mRNA.
ACCESSION   NM_027975 XM_130601 XM_902804 XM_902808 XM_910916 XM_921806
            XM_921817 XM_982681 XM_982712 XM_982744
VERSION     NM_027975.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2268)
  AUTHORS   Gura,M.A., Relovska,S., Abt,K.M., Seymour,K.A., Wu,T., Kaya,H.,
            Turner,J.M.A., Fazzio,T.G. and Freiman,R.N.
  TITLE     TAF4b transcription networks regulating early oocyte
            differentiation
  JOURNAL   Development 149 (3) (2022)
   PUBMED   35043944
REFERENCE   3  (bases 1 to 2268)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2268)
  AUTHORS   Ray,J.P., Staron,M.M., Shyer,J.A., Ho,P.C., Marshall,H.D.,
            Gray,S.M., Laidlaw,B.J., Araki,K., Ahmed,R., Kaech,S.M. and
            Craft,J.
  TITLE     The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling,
            Differentiation, and Metabolism of T Helper 1 and Follicular B
            Helper T Cells
  JOURNAL   Immunity 43 (4), 690-702 (2015)
   PUBMED   26410627
REFERENCE   5  (bases 1 to 2268)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663077.8 and AL669910.15.
            
            On Mar 23, 2023 this sequence version replaced NM_027975.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068129.1, AK159308.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-497               AL663077.8         87353-87849
            498-665             AL669910.15        4979-5146
            666-790             AL669910.15        8267-8391
            791-2268            AL669910.15        10294-11771
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.73 cM"
     gene            1..2268
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /note="family with sequence similarity 83, member D"
                     /db_xref="GeneID:71878"
                     /db_xref="MGI:MGI:1919128"
     exon            1..497
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..1781
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM83D"
                     /codon_start=1
                     /product="protein FAM83D isoform 1"
                     /protein_id="NP_082251.2"
                     /db_xref="CCDS:CCDS50788.1"
                     /db_xref="GeneID:71878"
                     /db_xref="MGI:MGI:1919128"
                     /translation="MAARFELLDDLPAACLSPCGPPNPTELFSEARRLALEQLLAGGP
                     DAWAAFLRRERLGRFLNADEVREVLGAAERPGEDGAAVAEDSFGSSHECSSGTYFPEQ
                     SDLEPPALELGWPSFYQGAYRGATRVEAHFQPRGAGAGGPYGCKDALRQQLRSAREVI
                     AVVMDVFSDIDIFRDLQESCRKRGVAVYILLDQTLLPHFLDMCMDLRVHPEQEKLMTV
                     RTITGNIYYARSGTKVVGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQV
                     VEHFDLEFRILYAQSEPISSKLLSNFQINSKFDHLADRKPQSKEPTLGNLLRMRLARL
                     SSTPRKSNLGPEEPPKDRAKPKRPDSEASTISDEDYFHSHKDQLEDSKVADAATQTEP
                     REEMAAVSLSEVGTQTSSSMMCVGTQTTVVTRAASSQATVWSKSTTTQTEADESFLPQ
                     GAQSKEGSPASKMSVSRSSSVRSSSSVSSQGSLASSVSSHVSLTAADLHTPAYPKYLG
                     LGTPHLDLCLRDSFRNLSKERQVHFTGIRSRLTQMLTVLSRRTLFTEHYLSYSPGSFT
                     RASTNLVSVRDIALYPPYQ"
     exon            498..665
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            666..790
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            791..2268
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2161..2166
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2179
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
     regulatory      2248..2253
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2268
                     /gene="Fam83d"
                     /gene_synonym="2310007D09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtggatcggt tctgggcact gccatggctg ctcgcttcga gctgttggac gaccttcccg
       61 cggcctgcct gtctccgtgc ggaccgccca accccacgga gctgttcagc gaggcgcggc
      121 gtctggctct cgagcagctg ctggccggtg gtcccgacgc ctgggccgcc ttcttacggc
      181 gtgagcggct gggccgcttc ctcaacgccg acgaggtgcg cgaggttctg ggcgctgccg
      241 agcggccggg cgaggatggg gcggcggtag cggaggactc gttcggctcc tctcacgaat
      301 gctcgtcggg cacctacttt ccggagcagt cggacctgga accgccggcg ttggagctcg
      361 gctggccttc cttctaccag ggtgcctacc gcggtgccac gcgtgtcgag gctcatttcc
      421 agccccgcgg cgcgggcgcc ggaggcccgt atggctgcaa ggatgcgctg cgccagcagt
      481 tgcgctccgc ccgagaggtg attgctgtgg taatggacgt tttctcagac atcgacatct
      541 tccgagacct gcaggagagc tgtaggaagc ggggggtggc tgtgtacatc ctcctggacc
      601 agactctgct cccccacttt ttggacatgt gcatggatct gagagttcat cctgagcagg
      661 aaaagctgat gacagttcgg acaattacag gaaatatcta ctatgcaagg tcaggaacaa
      721 aggttgtcgg gaaggttcat gagaagttca cactgattga cggaatccgg gtggcaacag
      781 gctcttacag ttttacctgg accgacggca aattaaacag cagtaacttg gtaattctgt
      841 ctggccaagt ggttgaacac tttgatctgg agttccggat cctgtatgct cagtcagagc
      901 ccatcagctc caaactcctg tccaacttcc agatcaatag caagtttgac catctggctg
      961 accgaaagcc acagtcgaag gagcccacac tgggcaatct gctgcgaatg aggctggcca
     1021 ggctctcaag tactcccagg aagagcaacc tgggcccaga ggagccgcca aaagacagag
     1081 ccaaacccaa gcgccctgac tctgaggctt ctaccatcag cgatgaagac tatttccaca
     1141 gccacaagga ccagctagag gatagtaagg tggctgatgc tgctacccaa acagagccca
     1201 gagaagagat ggctgcagta agcctgagtg aggtgggaac tcagactagt tccagcatga
     1261 tgtgtgttgg gacccaaacc acagttgtca ccagggcagc gagctcccag gccacagtgt
     1321 ggtccaagtc cactaccaca cagactgaag ctgacgagag cttccttcct cagggtgccc
     1381 agtccaaaga agggtcaccg gcatccaaga tgtcagtgtc gaggtcttcc agtgtgaggt
     1441 catcctcttc tgtgtcttcc cagggctcgc tggcaagctc ggtgagctcc catgtctccc
     1501 tgacggctgc tgatctccac actcccgcat accccaagta cctgggtctg ggcaccccgc
     1561 atctggatct gtgcctaagg gactcgttca gaaacttaag taaggagcgg caggtccact
     1621 tcactggcat caggtcccgg ctcacccaga tgctcaccgt gctctcacgg agaacgctct
     1681 tcacagagca ctacctcagc tacagccccg ggagctttac cagagcctct accaacctgg
     1741 tttctgtgag ggacatagcc ctttaccctc cctatcagtg actgccgggt tcagccagcc
     1801 ctctgtcctg aggccaacag agcctcacat gcatggcccc agccaccctc tcccacctga
     1861 cactgggcca cctttgcttt gattctgcag cattgtttga tatttttaat ttttgttctt
     1921 tagaaaccat ctgttggttt aaacactata ggtatttttt tctcatttgc acaattttaa
     1981 tattctatca ctacataagt gttttaaggt tggtttgaga gataaatact gttttatgtg
     2041 tgtgtgtatt ctctgtctta atgctttgag tcaccactgt ttttaaaatc agaatcatat
     2101 ttaaaagtta aacaccattg tttcttaact gactttctct tgaatatctg tgtttgtagt
     2161 attaaataag tatagacaac tttttgtttg cctggatttt gttcttcttt ctggcaaccc
     2221 tgcctttgtc tctaagggta catcataaat aaatatacta tataggta
//
