LOCUS       NM_001370926            1734 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 81, member B (Fam81b),
            mRNA.
ACCESSION   NM_001370926 XM_006517506
VERSION     NM_001370926.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1734)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Gm276 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154355.1 and CT010470.9.
            
            On Jun 13, 2019 this sequence version replaced XM_006517506.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.110572.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               AC154355.1         147940-148146       c
            208-305             AC154355.1         147464-147561       c
            306-370             AC154355.1         144863-144927       c
            371-614             CT010470.9         186307-186550       c
            615-733             CT010470.9         180850-180968       c
            734-863             CT010470.9         172910-173039       c
            864-970             CT010470.9         169562-169668       c
            971-1106            CT010470.9         148747-148882       c
            1107-1302           CT010470.9         146448-146643       c
            1303-1734           CT010470.9         136354-136785       c
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 40.96 cM"
     gene            1..1734
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /note="family with sequence similarity 81, member B"
                     /db_xref="GeneID:238726"
                     /db_xref="MGI:MGI:2685122"
     exon            1..207
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     CDS             198..1436
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /codon_start=1
                     /product="protein FAM81B"
                     /protein_id="NP_001357855.1"
                     /db_xref="GeneID:238726"
                     /db_xref="MGI:MGI:2685122"
                     /translation="MTSETDVNTSASLPAEEQPDPPDGPLPGSVIDQEKKVRLSPVKM
                     STKNATDLVEYVDKGCPFLPAMPSNQTSQLEDRLSHQERTVAFLLEQAFRIKEDISAC
                     LHGSQGFRKEESLARKLLESHIQTITSIVKKLNQNIELLEDQIRIRDQVTTGTNFAVQ
                     DLNIKHIQGVGDLRGRVARCDSSIVKLSGDIQFIRHECRQMEKSVQELASALETISKN
                     LDVKVMQLLGKIEASASEHTSNLKMVRGDYQHEMNLLEFKFNSLSKNIYEEVETNQKW
                     TENQFIKYGKDHLSHMNECLKVVQEKLEKSENKMEEKMLQLSSKLENFMNSQKQEAEI
                     NKVKTIENKVSKKMSQLEKRIWGELEKMQNDYQSGFKSIHDSLNSLQQIQKTKMDLEK
                     HKVQKDLKKLQRKIVELQEV"
     exon            208..305
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            306..370
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            371..614
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            615..733
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            734..863
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            864..970
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1106
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1302
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1734
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1714..1719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /note="hexamer: AATAAA"
     polyA_site      1734
                     /gene="Fam81b"
                     /gene_synonym="Gm276"
                     /note="major polyA site"
ORIGIN      
        1 caatgctcct caactgccct tggaaagatg tttcagaagt atgaaggttt tggtttgaat
       61 gtagtcagaa atccgtagta ttttggcttt ttaagaagga aagcttaaac aacctccaga
      121 acatatttct gttctctttc aaaaataaaa agcaactcaa caaaaagtaa taataataaa
      181 gctgggagac caacttcatg acttcagaaa cagatgtaaa cacaagtgcc tctctgcctg
      241 ccgaagaaca gcccgatcca cctgatggcc cccttcctgg ctcagtcatt gaccaagaaa
      301 agaaagtaag attatctcca gtcaaaatgt caactaagaa cgctacagat ctagttgagt
      361 atgttgacaa gggttgcccc tttcttcctg ccatgccaag caaccaaaca agtcagctag
      421 aagacaggct gagtcaccag gagcgcaccg tagccttcct ccttgaacag gctttccgaa
      481 tcaaggagga catctctgct tgcctccacg gaagccaggg gtttcgaaaa gaagaatctc
      541 ttgccaggaa gttactagaa agccacatac agaccatcac cagcatcgtc aagaaactca
      601 accaaaacat tgagctccta gaagaccaaa taagaatccg agaccaggtg accacaggaa
      661 ctaactttgc agtgcaggat ctaaacatca aacacataca aggagttgga gaccttcgcg
      721 gaagagtagc cagatgtgat tcaagcattg tgaagctttc cggagacatc cagttcatca
      781 gacatgagtg ccgacagatg gagaaatcag tgcaagaact tgcttctgcc ctagaaacca
      841 tttctaagaa cttggatgtg aaggtaatgc agcttttagg aaagatagag gcctctgcct
      901 ctgagcacac ctcaaattta aagatggtcc gaggagatta tcagcatgaa atgaacctct
      961 tagaattcaa atttaactca ctttctaaaa atatatatga agaagttgaa accaatcaaa
     1021 aatggaccga aaaccagttt atcaagtacg gaaaagacca cctgagccac atgaatgagt
     1081 gtctgaaggt tgtgcaggaa aagctggaaa aatctgagaa taagatggaa gaaaaaatgc
     1141 tgcaactttc aagcaagttg gagaatttta tgaactccca gaaacaggag gcagaaataa
     1201 ataaagtgaa gaccatagaa aataaagtgt ccaagaaaat gagccaatta gagaagcgga
     1261 tctgggggga actagagaaa atgcaaaatg actatcaatc aggatttaaa tcaatccacg
     1321 actccctcaa ttctctccaa caaatacaga aaacaaaaat ggatttagag aaacataaag
     1381 tacagaaaga cctaaagaaa ttacaacgta aaatagtgga acttcaagaa gtgtaacttt
     1441 gaagacactg tcttttccag cagctggtgc aagggtttgt tgggaaaagt tgtgaataag
     1501 aaaatgaata tctttaggct attacttctg gtatttctta tcacctctaa aagaaatcaa
     1561 cattccaggg ggaaaagaca caataaagca aaaagcttaa tgatgccttt aatttcttaa
     1621 tgaaaaatta agaaatttgt tttcatacat gcatagttat atttttattt gcccacaagt
     1681 aagaaaagca aaatttgtat cctgtacctg atgaataaag taagttcaag tata
//
