LOCUS       NM_175382               1270 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 72, member A (Fam72a),
            mRNA.
ACCESSION   NM_175382
VERSION     NM_175382.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1270)
  AUTHORS   Rogier,M., Moritz,J., Robert,I., Lescale,C., Heyer,V., Abello,A.,
            Martin,O., Capitani,K., Thomas,M., Thomas-Claudepierre,A.S.,
            Laffleur,B., Jouan,F., Pinaud,E., Tarte,K., Cogne,M.,
            Conticello,S.G., Soutoglou,E., Deriano,L. and Reina-San-Martin,B.
  TITLE     Fam72a enforces error-prone DNA repair during antibody
            diversification
  JOURNAL   Nature 600 (7888), 329-333 (2021)
   PUBMED   34819671
  REMARK    GeneRIF: Fam72a enforces error-prone DNA repair during antibody
            diversification.
REFERENCE   3  (bases 1 to 1270)
  AUTHORS   Feng,Y., Li,C., Stewart,J.A., Barbulescu,P., Seija Desivo,N.,
            Alvarez-Quilon,A., Pezo,R.C., Perera,M.L.W., Chan,K., Tong,A.H.Y.,
            Mohamad-Ramshan,R., Berru,M., Nakib,D., Li,G., Kardar,G.A.,
            Carlyle,J.R., Moffat,J., Durocher,D., Di Noia,J.M., Bhagwat,A.S.
            and Martin,A.
  TITLE     FAM72A antagonizes UNG2 to promote mutagenic repair during antibody
            maturation
  JOURNAL   Nature 600 (7888), 324-328 (2021)
   PUBMED   34819670
  REMARK    GeneRIF: FAM72A antagonizes UNG2 to promote mutagenic repair during
            antibody maturation.
REFERENCE   4  (bases 1 to 1270)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1270)
  AUTHORS   Nehar,S., Mishra,M. and Heese,K.
  TITLE     Identification and characterisation of the novel amyloid-beta
            peptide-induced protein p17
  JOURNAL   FEBS Lett 583 (19), 3247-3253 (2009)
   PUBMED   19755123
REFERENCE   6  (bases 1 to 1270)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 1270)
  AUTHORS   Charles,C.H., Abler,A.S. and Lau,L.F.
  TITLE     cDNA sequence of a growth factor-inducible immediate early gene and
            characterization of its encoded protein
  JOURNAL   Oncogene 7 (1), 187-190 (1992)
   PUBMED   1741163
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120217.13.
            
            On Oct 20, 2022 this sequence version replaced NM_175382.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC106123.1, AK041641.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-866               AC120217.13        32896-33761
            867-944             AC120217.13        35563-35640
            945-1069            AC120217.13        38718-38842
            1070-1270           AC120217.13        43744-43944
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 56.99 cM"
     gene            1..1270
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /note="family with sequence similarity 72, member A"
                     /db_xref="GeneID:108900"
                     /db_xref="MGI:MGI:1919669"
     exon            1..866
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /inference="alignment:Splign:2.1.0"
     CDS             715..1164
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /codon_start=1
                     /product="protein FAM72A"
                     /protein_id="NP_780591.1"
                     /db_xref="CCDS:CCDS15270.1"
                     /db_xref="GeneID:108900"
                     /db_xref="MGI:MGI:1919669"
                     /translation="MSTNNCTFKDRCVSILCCKFCKQVLSSRGMKAVLLADTDIDLFS
                     TDIPPTNTVDFIGRCYFTGICKCKLKDIACLKCGNIVGYHVIVPCSSCLLSCNNGHFW
                     MFHSQAVYGINRLDATGVNLLLWGNLPETEECTDEETLEISAEEYIR"
     exon            867..944
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1069
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1270
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1240..1245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /note="hexamer: AGTAAA"
     polyA_site      1270
                     /gene="Fam72a"
                     /gene_synonym="2700049P18Rik; P17"
                     /note="major polyA site"
ORIGIN      
        1 gcaaaacccg gcgtgttcgc tgactgactg cagcgcgaac tgagcctatt ccgaggcttc
       61 tcccctccac ctcgctacac cgctgctcac ttcggagcga ccgctgtgga agagacctta
      121 cgggttacgg gccgcaagtg cgagagctcg gccgggagag gacgccgaga gccgtggtgc
      181 aagggagaaa gcccacgggc gagctccgag aagagggagc gggacggggc cagagcccgc
      241 gtggaaaggg ctgaggggcg ttgaatccta cgaagaagcc gcgtggagct gagcaagaat
      301 tggagcgctc tgcgggcgga gctcgcgctg ggagtggtca gagaggcgag gctttaaagg
      361 gaagaagccc gctgggaact gggaaatcgc ccaattccgg agccggggtc ggagctgaag
      421 agtagaagat tcttgaagac cagagaaagt taaacctgtt gcggaagttt cccttcaact
      481 ccacttgtct ctccccacct tgaactccat ttcccttccc tccccaagtc aaaaggaagt
      541 aaaatttgct cttcctactc aataaatact aagtttccct ttccaccagg aaaataggac
      601 tctcttccca gttttagagc gtagagaacg agaggccttc cgtcttgatt gttagcctga
      661 ggaaatcaaa gtttcccctt tcaaaattct gcacctcttt caacgtggga cgctatgtct
      721 accaacaact gtactttcaa agaccgatgc gtatccatcc tgtgttgcaa attctgtaaa
      781 caagttctca gctctagggg aatgaaggct gttttgctgg ctgatactga catagacctt
      841 ttctctacag acatccctcc taccaacaca gtggatttca ttggaagatg ctatttcaca
      901 ggaatctgca aatgtaaact gaaggacatc gcatgtttga aatgtgggaa cattgtaggc
      961 taccacgtaa ttgttccatg tagttcctgc cttctttcct gcaacaatgg acacttctgg
     1021 atgtttcaca gtcaggcggt ttatggtata aacagactag atgccactgg tgtaaacctc
     1081 ctactttggg gcaatttgcc agagacagaa gaatgtacag atgaagaaac gctagagatt
     1141 tcagcagaag agtatattcg atgaaagaat tatgatgtat atgaagtatt ttataatttt
     1201 tctatttaaa gtatttaatt ggtaaatttt aacattgcta gtaaagattt gccggtggtt
     1261 taaaatgcca
//
