LOCUS       NM_138607               1383 bp    mRNA    linear   ROD 18-MAR-2025
DEFINITION  Mus musculus family with sequence similarity 50, member A (Fam50a),
            mRNA.
ACCESSION   NM_138607
VERSION     NM_138607.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Wang,W., Xing,J., Zhang,X., Liu,H., Liu,X., Jiang,H., Xu,C.,
            Zhao,X. and Hu,Z.
  TITLE     Control of ciliary transcriptional programs during spermatogenesis
            by antagonistic transcription factors
  JOURNAL   Elife 13, 94754 (2025)
   PUBMED   40009443
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1383)
  AUTHORS   Kim,Y., Hur,S.W., Jeong,B.C., Oh,S.H., Hwang,Y.C., Kim,S.H. and
            Koh,J.T.
  TITLE     The Fam50a positively regulates ameloblast differentiation via
            interacting with Runx2
  JOURNAL   J Cell Physiol 233 (2), 1512-1522 (2018)
   PUBMED   28574578
  REMARK    GeneRIF: Fam50a might be a new positive regulator of ameloblast
            differentiation, increasing binding affinity of Runx2 to Ambn
            promoter by physically interacting with Runx2.
REFERENCE   3  (bases 1 to 1383)
  AUTHORS   Sedlacek,Z., Munstermann,E., Dhorne-Pollet,S., Otto,C., Bock,D.,
            Schutz,G. and Poustka,A.
  TITLE     Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of
            an ancient functional retroposon differentially expressed in testis
  JOURNAL   Genomics 61 (2), 125-132 (1999)
   PUBMED   10534398
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK008402.1 and Y18505.1.
            
            On Oct 27, 2009 this sequence version replaced NM_138607.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y18505.1, AK008402.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               AK008402.1         2-294
            294-701             Y18505.1           259-666
            702-1082            AK008402.1         703-1083
            1083-1383           Y18505.1           1048-1348
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.98 cM"
     gene            1..1383
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /note="family with sequence similarity 50, member A"
                     /db_xref="GeneID:108160"
                     /db_xref="MGI:MGI:1351626"
     exon            1..293
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..1202
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /note="protein XAP-5"
                     /codon_start=1
                     /product="protein FAM50A"
                     /protein_id="NP_613073.2"
                     /db_xref="CCDS:CCDS41021.1"
                     /db_xref="GeneID:108160"
                     /db_xref="MGI:MGI:1351626"
                     /translation="MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSN
                     IDKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQLKLE
                     KLREKERKKEAKRKISSLSFTLEEEEEGVEEEEEMAMYEEELEREEITTKKKKLGKNP
                     DVDTSFLPDRDREEEENRLREELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMK
                     KGNTMQQFLQKALEILRKDFSELRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKS
                     GPLFNFDVHDDVRLLSDATVEKDESHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWD
                     KYTIR"
     exon            294..378
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            379..478
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            479..624
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            625..701
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            702..768
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            769..830
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            831..907
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            908..962
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1011
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1082
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1193
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1383
                     /gene="Fam50a"
                     /gene_synonym="D0HXS9928E; XAP-5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcagctgac taaattgccg ccgccactgc cgtcgccgtc gcctccacga cttctccaag
       61 caaaagtcac tgttgccgct gtcgtcgctg ccaacgccgc cgctgccgct gccgctgccg
      121 ctgccgctgc cgctgcctcc gctgaaaccg ccactgcctt cgctgaaacc gctgctgcca
      181 ccatggccca gtacaagggc gctgcaagcg aggcgggacg cgccatgcac ctaatgaaga
      241 agagggagaa gcagcgtgag caaatggagc agatgaagca gaggattgca gaggagaaca
      301 taatgaaatc taacattgac aagaaattct ctgcacacta tgatgctgtg gaagcagagc
      361 tcaagtccag tactgtgggt cttgtgactc tgaatgacat gaaggccaaa caggaggcac
      421 tggtgaagga gcgagagaaa cagctggcaa aaaaggagca gtcaaaggag ctacagctga
      481 aactagagaa gcttcgagag aaggagcgca agaaggaggc caagcggaag atctccagcc
      541 tgtccttcac cttggaggaa gaggaggagg gagttgaaga ggaggaagag atggctatgt
      601 acgaggagga actggagagg gaagagatca ccacaaagaa aaagaaattg gggaagaacc
      661 ctgatgtgga cacaagcttc ttgcctgacc gggaccggga ggaggaggag aatcggcttc
      721 gggaagagct gcgccaggag tgggaagcca agcaggaaaa aatcaagagt gaagagattg
      781 aaatcacctt tagttactgg gatggctctg ggcaccggcg cacagttaag atgaagaaag
      841 gcaacacgat gcagcagttc ctacagaaag cactagagat cttgcggaaa gacttcagtg
      901 aactcaggtc agcaggggtg gaacagctca tgtacatcaa ggaggattta atcatccccc
      961 atcatcacag cttctatgac ttcatcgtta ccaaggcacg aggaaaaagt gggccactct
     1021 tcaacttcga cgttcatgat gatgtacgac tgctcagtga tgccactgtg gagaaggatg
     1081 agtcacatgc aggcaaagta gtgctaagga gctggtatga gaagaacaag cacatttttc
     1141 ctgccagtcg ctgggagccc tatgacccag aaaagaaatg ggacaagtac acgatccggt
     1201 gagcatccaa aagtggacat gaccttggct ctccccagcg tgcctccatg tctccagggc
     1261 tcaggtgacc atgccagagc cctctgtgag gatggtagtt gctattcctt gacctgatgt
     1321 tatcattact gattttccct tttacaataa aaaagtccac atgttggagc tggagtgcct
     1381 gca
//
