LOCUS       NM_001400577            1086 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 47, member E (Fam47e),
            transcript variant 15, mRNA.
ACCESSION   NM_001400577
VERSION     NM_001400577.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1086)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1086)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1086)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123850.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189682.11942.1, DV648863.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC123850.3         141550-141723
            175-319             AC123850.3         144582-144726
            320-1086            AC123850.3         160529-161295
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.09 cM"
     gene            1..1086
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="family with sequence similarity 47, member E"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
     exon            1..174
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..418
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="isoform 14 is encoded by transcript variant 15"
                     /codon_start=1
                     /product="protein FAM47E isoform 14"
                     /protein_id="NP_001387506.1"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
                     /translation="MLSCIQPLPTLHFLCIIREHLACDCLPRCLSPSCIAEATQRPKK
                     TLISRSGQWLCEEKSSKVDSLYKDRLLHDDVHRGVTDFCHWAEDLFLEKIYAEEKNKS
                     ENIKAPKKLTQTEKNPGSR"
     exon            175..319
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            320..1086
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1062..1067
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="hexamer: AATAAA"
     polyA_site      1086
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="major polyA site"
ORIGIN      
        1 gggcctgggc tcagtgtcac ttcagcagag agactctctc tgtagaaatt ggatgctgtc
       61 ctgcatccag ccgcttccca ccttacattt tctttgcatc atccgtgagc acctggcatg
      121 tgattgtctg cctcgatgtc tctctccatc ctgcatagcc gaagccacgc aaaggcctaa
      181 gaagacgctg atctcacgtt caggccagtg gctttgtgaa gaaaagtcaa gcaaagtgga
      241 ttcactctat aaagacagac tcctccatga tgacgtacac agaggagtca ccgacttctg
      301 ccactgggcc gaggaccttt tccttgagaa gatatatgcg gaggagaaaa ataaatctga
      361 aaatattaag gctcctaaaa aactcacgca aacagagaag aatcccggga gcagatgagt
      421 cggctttgat tgacagcatc cttggatact gccccattag tttaattaat aagtagaata
      481 tagcagtgcc ctccgtgaag gcttcaacct ggcagcatct acaaatataa aactgaacac
      541 aaatgtcttt ctaaacagct ttttaaaggc tttagggttt ttttgtagta tttttagtta
      601 tgtacagctg tgtatgtctg catgtgggta ggtgcacaca agtctaggag ccttcagaag
      661 cctgaagcgt tgaatgccct ggagccgcag ttacagaggg ttgtgagcca ccatgtgggt
      721 gctgggaact gaaccttggt cctctcgacg aacagtgagc tgtcccgatg gctgatccat
      781 ctctccagcc tccactgatc aatgttttgt ttgcttgttt gtttggtttg ggggtttggc
      841 cttctttagg gagagtcttg ctatgtggcc taggctgacc tctaattagt catccccctg
      901 tgttagcctc tcagggtcta gagttgcagc tctgcaccaa cacacctggt gcacaaaata
      961 atacattttg tatatttacc aactatgggc tcaatattcg tgtgtagtcc tctcacgctt
     1021 tcgtgttatg aagatgccat aaatgattga tttcttgtaa aaataaaatc ataggcaaag
     1081 tcacaa
//
