LOCUS       NM_001379208            1175 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 47, member E (Fam47e),
            transcript variant 11, mRNA.
ACCESSION   NM_001379208 XM_011249504
VERSION     NM_001379208.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1175)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1175)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123850.3.
            
            On Mar 25, 2020 this sequence version replaced XM_011249504.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189682.165843.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC123850.3         141550-141723
            175-330             AC123850.3         155269-155424
            331-408             AC123850.3         157529-157606
            409-1175            AC123850.3         160529-161295
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.09 cM"
     gene            1..1175
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="family with sequence similarity 47, member E"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
     exon            1..174
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..507
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="isoform 11 is encoded by transcript variant 11"
                     /codon_start=1
                     /product="protein FAM47E isoform 11"
                     /protein_id="NP_001366137.1"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
                     /translation="MSLSILHSRSHAKNPQKPKRVKMRYGAWYLNTSLWKRQRADEPL
                     VDPMVSHKAQDSTFKEQLQEQGELLAGLRGTAAFKDFILSRGYRMPRFLEKIYAEEKN
                     KSENIKAPKKLTQTEKNPGSR"
     exon            175..330
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            331..408
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            409..1175
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1151..1156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="hexamer: AATAAA"
     polyA_site      1175
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="major polyA site"
ORIGIN      
        1 gggcctgggc tcagtgtcac ttcagcagag agactctctc tgtagaaatt ggatgctgtc
       61 ctgcatccag ccgcttccca ccttacattt tctttgcatc atccgtgagc acctggcatg
      121 tgattgtctg cctcgatgtc tctctccatc ctgcatagcc gaagccacgc aaagaatcct
      181 cagaagccga agcgggtaaa gatgaggtac ggagcctggt acctgaacac cagcttgtgg
      241 aagaggcaaa gagcggatga acctctggtc gaccccatgg tctcacacaa agctcaagat
      301 tcaaccttta aagagcagct tcaggagcag ggggagctgc ttgcaggcct gcgagggaca
      361 gcagccttta aggacttcat tctaagcagg ggctacagga tgcccaggtt ccttgagaag
      421 atatatgcgg aggagaaaaa taaatctgaa aatattaagg ctcctaaaaa actcacgcaa
      481 acagagaaga atcccgggag cagatgagtc ggctttgatt gacagcatcc ttggatactg
      541 ccccattagt ttaattaata agtagaatat agcagtgccc tccgtgaagg cttcaacctg
      601 gcagcatcta caaatataaa actgaacaca aatgtctttc taaacagctt tttaaaggct
      661 ttagggtttt tttgtagtat ttttagttat gtacagctgt gtatgtctgc atgtgggtag
      721 gtgcacacaa gtctaggagc cttcagaagc ctgaagcgtt gaatgccctg gagccgcagt
      781 tacagagggt tgtgagccac catgtgggtg ctgggaactg aaccttggtc ctctcgacga
      841 acagtgagct gtcccgatgg ctgatccatc tctccagcct ccactgatca atgttttgtt
      901 tgcttgtttg tttggtttgg gggtttggcc ttctttaggg agagtcttgc tatgtggcct
      961 aggctgacct ctaattagtc atccccctgt gttagcctct cagggtctag agttgcagct
     1021 ctgcaccaac acacctggtg cacaaaataa tacattttgt atatttacca actatgggct
     1081 caatattcgt gtgtagtcct ctcacgcttt cgtgttatga agatgccata aatgattgat
     1141 ttcttgtaaa aataaaatca taggcaaagt cacaa
//
