LOCUS       NM_001379203            1269 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 47, member E (Fam47e),
            transcript variant 6, mRNA.
ACCESSION   NM_001379203 XM_030254639
VERSION     NM_001379203.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1269)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1269)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1269)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123850.3.
            
            On Mar 25, 2020 this sequence version replaced XM_030254639.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR2680379.173017.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC123850.3         141550-141723
            175-319             AC123850.3         144582-144726
            320-421             AC123850.3         148485-148586
            422-502             AC123850.3         149617-149697
            503-1269            AC123850.3         160529-161295
FEATURES             Location/Qualifiers
     source          1..1269
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.09 cM"
     gene            1..1269
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="family with sequence similarity 47, member E"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
     exon            1..174
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..601
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="isoform 6 is encoded by transcript variant 6"
                     /codon_start=1
                     /product="protein FAM47E isoform 6"
                     /protein_id="NP_001366132.1"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
                     /translation="MLSCIQPLPTLHFLCIIREHLACDCLPRCLSPSCIAEATQRPKK
                     TLISRSGQWLCEEKSSKVDSLYKDRLLHDDVHRGVTDFCHWAEDLGSSAIEEEFVLQQ
                     FDIGYQTRRSCDALLRLRLNQDKLFINRPPSLREHCGHWSEPRSSGRAFLEKIYAEEK
                     NKSENIKAPKKLTQTEKNPGSR"
     exon            175..319
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            320..421
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            422..502
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            503..1269
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1245..1250
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="hexamer: AATAAA"
     polyA_site      1269
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="major polyA site"
ORIGIN      
        1 gggcctgggc tcagtgtcac ttcagcagag agactctctc tgtagaaatt ggatgctgtc
       61 ctgcatccag ccgcttccca ccttacattt tctttgcatc atccgtgagc acctggcatg
      121 tgattgtctg cctcgatgtc tctctccatc ctgcatagcc gaagccacgc aaaggcctaa
      181 gaagacgctg atctcacgtt caggccagtg gctttgtgaa gaaaagtcaa gcaaagtgga
      241 ttcactctat aaagacagac tcctccatga tgacgtacac agaggagtca ccgacttctg
      301 ccactgggcc gaggaccttg gaagctctgc cattgaggaa gagttcgtcc tgcagcagtt
      361 tgacatcggc tatcagacta gacgcagctg tgatgcgctt ctcaggctga ggctgaacca
      421 ggacaaactc ttcatcaata gaccaccttc cctgcgagaa cactgtgggc actggagtga
      481 acctcggtcc tctggaagag cattccttga gaagatatat gcggaggaga aaaataaatc
      541 tgaaaatatt aaggctccta aaaaactcac gcaaacagag aagaatcccg ggagcagatg
      601 agtcggcttt gattgacagc atccttggat actgccccat tagtttaatt aataagtaga
      661 atatagcagt gccctccgtg aaggcttcaa cctggcagca tctacaaata taaaactgaa
      721 cacaaatgtc tttctaaaca gctttttaaa ggctttaggg tttttttgta gtatttttag
      781 ttatgtacag ctgtgtatgt ctgcatgtgg gtaggtgcac acaagtctag gagccttcag
      841 aagcctgaag cgttgaatgc cctggagccg cagttacaga gggttgtgag ccaccatgtg
      901 ggtgctggga actgaacctt ggtcctctcg acgaacagtg agctgtcccg atggctgatc
      961 catctctcca gcctccactg atcaatgttt tgtttgcttg tttgtttggt ttgggggttt
     1021 ggccttcttt agggagagtc ttgctatgtg gcctaggctg acctctaatt agtcatcccc
     1081 ctgtgttagc ctctcagggt ctagagttgc agctctgcac caacacacct ggtgcacaaa
     1141 ataatacatt ttgtatattt accaactatg ggctcaatat tcgtgtgtag tcctctcacg
     1201 ctttcgtgtt atgaagatgc cataaatgat tgatttcttg taaaaataaa atcataggca
     1261 aagtcacaa
//
