LOCUS       NM_001379201             953 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 47, member E (Fam47e),
            transcript variant 4, mRNA.
ACCESSION   NM_001379201
VERSION     NM_001379201.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 953)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 953)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123850.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.936233.1,
                                           SRR7652917.848985.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               AC123850.3         125061-125160
            101-437             AC123850.3         132234-132570
            438-571             AC123850.3         135941-136074
            572-953             AC123850.3         144582-144963
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 47.09 cM"
     gene            1..953
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="family with sequence similarity 47, member E"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
     exon            1..100
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..725
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="isoform 4 is encoded by transcript variant 4"
                     /codon_start=1
                     /product="protein FAM47E isoform 4"
                     /protein_id="NP_001366130.1"
                     /db_xref="GeneID:384198"
                     /db_xref="MGI:MGI:2686227"
                     /translation="MAECGQRLQPTTLAPRLLRERQNCGWYLGNLPPKRFIRRNRLTC
                     QGFLNSRHWVFVKEDNFRKDCPPHQSPKDAFLPLIHRGAPSATPEKRQSTLLKGATLL
                     SKLSKAGKAFLEDVEAEAAQHPLTLYPQLTEALPAELLLQVLEVLDPERKLEDVWAYC
                     QDTRKPMKEPTELVGKRSSQERPPKKTLISRSGQWLCEEKSSKVDSLYKDRLLHDDVH
                     RGVTDFCHWAEDLVS"
     exon            101..437
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            438..571
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     exon            572..953
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /inference="alignment:Splign:2.1.0"
     regulatory      937..942
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="hexamer: AATATA"
     polyA_site      953
                     /gene="Fam47e"
                     /gene_synonym="C730043O17; Gm1381"
                     /note="major polyA site"
ORIGIN      
        1 gccacacaag actgggcagt gccatggcgg agtgtgggca gcggctccag cccacgaccc
       61 tggctcctag actgctgagg gagcgccaga actgcgggtg gtacctcggg aacctgcctc
      121 ccaagcgttt cataaggcgg aaccggctga catgccaggg cttcttgaac agccggcact
      181 gggtgtttgt gaaagaggat aacttcagga aagactgccc cccgcaccag agccccaagg
      241 atgcctttct acctcttatt catcgcggag cccccagtgc taccccagag aagaggcaga
      301 gcacactgct caagggggca acgctgttgt ctaagctttc gaaagctggg aaggcattcc
      361 tggaggatgt ggaagctgag gcggctcagc acccgctgac tctctaccca caacttacag
      421 aagctctgcc tgctgagctc ttattgcagg tgctggaggt actggaccct gagaggaagc
      481 tggaggatgt gtgggcttat tgccaggata ccaggaagcc aatgaaggaa cccacagagc
      541 ttgtaggaaa acgctcttcc caagaacgcc cgcctaagaa gacgctgatc tcacgttcag
      601 gccagtggct ttgtgaagaa aagtcaagca aagtggattc actctataaa gacagactcc
      661 tccatgatga cgtacacaga ggagtcaccg acttctgcca ctgggccgag gaccttgtaa
      721 gttagcagtg acacctaaag ttaccctcaa gagtcaagct cagaggctgg agagatggct
      781 tagtggttaa gagcaccaac tgctcttcca gaggtcctga gttcagttcc cagcaaccac
      841 atggtggctc acaaaccatg gtggctacaa tgagatcaga tgccgtcttc tggtgtgtct
      901 gaagacagag actgtgctca caacatgaaa taaataaata tatctttaat aaa
//
