LOCUS       NM_026455               3165 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus family with sequence similarity 32, member A (Fam32a),
            mRNA.
ACCESSION   NM_026455
VERSION     NM_026455.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3165)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3165)
  AUTHORS   Chen,X., Zhang,H., Aravindakshan,J.P., Gotlieb,W.H. and Sairam,M.R.
  TITLE     Anti-proliferative and pro-apoptotic actions of a novel human and
            mouse ovarian tumor-associated gene OTAG-12: downregulation,
            alternative splicing and drug sensitization
  JOURNAL   Oncogene 30 (25), 2874-2887 (2011)
   PUBMED   21339736
  REMARK    GeneRIF: study showed that hOTAG-12b increases mRNAs of
            pro-apoptotic genes such as BAD, GADD45alpha and CIEDB, while
            inhibiting anti-apoptotic NAIP and Akt1 expression, suggesting that
            hOTAG-12b-induced apoptosis might be p53-independent
REFERENCE   3  (bases 1 to 3165)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158898.7.
            
            On Feb 8, 2019 this sequence version replaced NM_026455.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011922.1, SRR1660825.66718.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AC158898.7         40107-40222         c
            117-258             AC158898.7         39885-40026         c
            259-312             AC158898.7         37986-38039         c
            313-3165            AC158898.7         34933-37785         c
FEATURES             Location/Qualifiers
     source          1..3165
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.9 cM"
     gene            1..3165
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="family with sequence similarity 32, member A"
                     /db_xref="GeneID:67922"
                     /db_xref="MGI:MGI:1915172"
     exon            1..116
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..381
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="ovarian tumor associated gene-12"
                     /codon_start=1
                     /product="protein FAM32A"
                     /protein_id="NP_080731.1"
                     /db_xref="CCDS:CCDS52595.1"
                     /db_xref="GeneID:67922"
                     /db_xref="MGI:MGI:1915172"
                     /translation="MEAYEQVQKGPLKLKGVAELGVTKRKKKKKDKDKAKMLEAMGTS
                     KKSEEEKRRCLDKRTPAQAAFEKMQEKRQMERILKKASKTHKQRVEDFNRHLDTLTEH
                     YDIPKVSWTK"
     exon            117..258
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /inference="alignment:Splign:2.1.0"
     exon            259..312
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /inference="alignment:Splign:2.1.0"
     exon            313..3165
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1135..1140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="hexamer: AATAAA"
     polyA_site      1154
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="major polyA site"
     regulatory      1543..1548
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="hexamer: AATATA"
     polyA_site      1566
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
     polyA_site      1597
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
     regulatory      1885..1890
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="hexamer: AATAAA"
     polyA_site      1908
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
     regulatory      2141..2146
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
                     /note="hexamer: ATTAAA"
     polyA_site      2161
                     /gene="Fam32a"
                     /gene_synonym="2510049I19Rik; OTAG-12; Otag12"
ORIGIN      
        1 aggaagtgtg gcggagttcc cggggcacgg cttgcgagcg ctatggaggc ctacgagcaa
       61 gtccagaagg gccccctgaa gctgaaaggc gtggcagagc tcggcgtgac aaagcggaag
      121 aagaagaaga aagacaaaga caaggccaag atgctggagg ccatggggac gagcaagaag
      181 agcgaggagg agaaaaggcg ctgcctggac aagcgcacgc cggcgcaggc agccttcgaa
      241 aagatgcagg agaagcggca aatggaaaga atcctgaaga aggcatcaaa aacccacaaa
      301 cagagagtgg aggacttcaa ccgacacctg gatacactca ctgagcacta tgacattccc
      361 aaagtcagct ggaccaagta acctgcccct ggtgcaaaaa ggcagaaggc caggttgaca
      421 gtgttttgtc ttgtccctcc gtgttttcta gaatgtttta cacctggctg gtgaatctgc
      481 tgagaccagg ttttctgaga cttgattaaa gtcagggtgt cctttcactg ggttttggtt
      541 ttggggtagt tccctttcct gtttggacag caacattgta gattgatatg ctgaggtcat
      601 ttctgggtga aggccttgga aggatggccc ccctcccacc cccattgcgg catctgtctt
      661 cacttacacc acaatgccag gacagaaagc tcacgtggac caccacagaa gttcccacag
      721 tgctgctcta ttttgggcca cctggacatc agattgcatc tgcaacacca cctgaagcaa
      781 gagtgggaca caggacacag gtctgcagca catagcctgt cccacagtcc accctgtaga
      841 ctgccatggc agatgttgct aatctccgtt ctcagtgatg gcacctgagt ttttaagtat
      901 gtggcatgtg gcataagccg ggttggcatt cctggtctaa ggagaccaaa tgctagacgt
      961 ggcccaggca gagtgccagc agacatggtg tagtggtgca gatgctgcag agctgtggca
     1021 tctgagggac taaggggacc acttgaagag tttctgcaca cgctgttgag agatgcagct
     1081 ccttttgcca tagatactga aagaatgaca aatccgtgga gctgacatgt ctggaataaa
     1141 gtgaatacca gttatggagt gtgaatgttg tctgtcctgg ctgtccatca cagggacacc
     1201 tttccattct cgtccctgaa gaatgaagaa tgcactccaa ctcagcttgt gagacttggc
     1261 tgcaagtgat tttacccact gagctgtgtc acagtcaggt ggactgtgtt cacacctgag
     1321 ggagatggtg tgtgcatacc ttgtctcaag tgtttagaat ctttgtggat ttggggattt
     1381 ttccagattt ggggaatagg gaacacaatg atttttgtaa tatgtaatga ggtgttgcag
     1441 tgactgtcac agatttgcat acatttgatt tctgttcgat ttgctcctgt gcacatagcc
     1501 taaagtcata ttaatttttt tctgtcttcg aacatagcat acaatataca cagtcttttt
     1561 gaagaacttt gtgcgtgaaa cagatatatg agatttactt gtttggggtt ttttgtttga
     1621 cttggagcgg ggttggagac atggggttgg ctgtcctgaa acactatgta gaccaagcta
     1681 ttagattctc ttccttctgt ctctggagtg ctagaattga aggcatgcac taccatgccc
     1741 ttttttgctt cctttaccta ggttctatag ctcaggctgc caatccatag cctgaagacc
     1801 taagttcaag tcccaggatc cacatgctgg aagaagagaa ctgattccca caaattatcc
     1861 tttgaactca tacacaatac acacaataaa tatttaaaca aaaagtaagg aggagccggg
     1921 tgtggtggca cacgccttta atcccagcac tcgggaggca gaggcaggcg gatttctgag
     1981 ttcgaggcca gcctggtcta caaagtgaat tcgaggacaa ccagggctac acagtctcaa
     2041 aaccctgtct cgaaaaaccc aaaaaggggg gggggataag aaggaaatgg gctaatatga
     2101 tcaaaataca aaatattaca tgtatggaag tggcagagaa attaaaaaaa tttatactgg
     2161 gtcttactag ataactctgg ctggcctgga atacagatct gcctgcctct gccttccaag
     2221 tgctactaat atttttaagt tatgtgtcca tgtgggtgtg tatacgtgag tgcaggtgtc
     2281 cacagaggcc agaggagtca aatcacctgg aactggagta acaggcagtt gtgacgcacc
     2341 agatacagtg ttgggaacaa tttggagaga gctcagtggt tacgagtgaa tactggcctg
     2401 gagagatggc tcagtggtta agaacactag ctgctctttc agagatcctg tggctcacaa
     2461 ctatttataa tgggatctga tgtcattgtc tggcatgcag ctatacatgc acatagagga
     2521 ctgatataaa tattttctaa aaaaaaaaat actgctgcag tcctaaaaaa ctgaaggggc
     2581 tgggtggggg ggggagcgga gctcttgcta cccaaactga aaacctgggt ttgatatctg
     2641 gtacctacat gatggagaaa gctgacccct gccactcttc ctctgacctc cctattgaag
     2701 aatgaaaaat tactggcctc ttgtaagaac atgaattttt tacctcggag cccaccccct
     2761 cccatctaga gattgttctc ggaacactcc taaacttttc accccaaaac tcctcaccct
     2821 aaagttcgaa aaaactgttc caagaacatt tttgagataa aggcctcctg acgtagattc
     2881 cttgatagga catgactcct tagttaccta gattcctttg gcagaactcc ctagtgatgt
     2941 aaacttgtac ttttcctgcc cagttctccc cctttgagtt ttactatata agcctgtgaa
     3001 aaattttggc tgactgtcga gactcctcta ccctgtgcta aggtgtatga gtttcgaccc
     3061 cagagctctg tgtgctttca tgttgctgct ttatttcgac cccagagctc tggtctgtgt
     3121 gctttcatgt cgctgcttta ttaaatctta ccttctacat tttat
//
